Facilitates the calculation of 40 different insulin sensitivity indices based on fasting, oral glucose tolerance test (OGTT), lipid (adipose), tracer (palmitate and glycerol rate), and DXA (fat mass) measurement values. Enables easy and accurate assessment of insulin sensitivity, critical for understanding and managing metabolic disorders like diabetes and obesity. Indices calculated are described in Gastaldelli (2022) <doi:10.1002/oby.23503>, Suleman (2024) <doi:10.1210/clinem/dgae275>, and Lorenzo (2010) <doi:10.1210/jc.2010-1144>.

This package contains several tools to treat imaging flow cytometry data from ImageStream® and FlowSight® cytometers ('Amnis® Cytek®'). Provides an easy and simple way to read and write .fcs, .rif, .cif and .daf files. Information such as masks, features, regions and populations set within these files can be retrieved for each single cell. In addition, raw data such as images stored can also be accessed. Users, may hopefully increase their productivity thanks to dedicated functions to extract, visualize, manipulate and export IFC data. Toy data example can be installed through the IFCdata package of approximately 32 MB, which is available in a drat repository <https://gitdemont.github.io/IFCdata/>. See file COPYRIGHTS and file AUTHORS for a list of copyright holders and authors.

This package provides functions to Interact with the ICES Data Submission Utility (DATSU) <https://datsu.ices.dk/web/index.aspx>.

This package provides user-friendly and configurable print debugging via a single function, ic(). Wrap an expression in ic() to print the expression, its value and (where available) its source location. Debugging output can be toggled globally without modifying code.

This package provides functions to download, clean, and structure open data from the Brazilian Federal Revenue (Receita Federal do Brasil - RFB) regarding Personal Income Tax (IRPF) statements. Includes a data dictionary and categorized metadata for several sections such as assets, rights, debts, and income brackets. More information about the data source can be found at <https://dados.gov.br/dados/conjuntos-dados/grandes-nmeros-do-imposto-de-renda-da-pessoa-fsica>.

This package provides functionality to perform a likelihood-free method for estimating the parameters of complex models that results in a simulated sample from the posterior distribution of model parameters given targets. The method begins with a accept/reject approximate bayes computation (ABC) step applied to a sample of points from the prior distribution of model parameters. Accepted points result in model predictions that are within the initially specified tolerance intervals around the target points. The sample is iteratively updated by drawing additional points from a mixture of multivariate normal distributions, accepting points within tolerance intervals. As the algorithm proceeds, the acceptance intervals are narrowed. The algorithm returns a set of points and sampling weights that account for the adaptive sampling scheme. For more details see Rutter, Ozik, DeYoreo, and Collier (2018) <arXiv:1804.02090>.

Includes a collection of shiny applications to demonstrate or to explore fundamental item response theory (IRT) concepts such as estimation, scoring, and multidimensional IRT models.

Four datasets are provided here from the Intendo game Super Jetroid'. It is data from the 2015 year of operation and it comprises a revenue table ('all_revenue'), a daily users table ('users_daily'), a user summary table ('user_summary'), and a table with data on all user sessions ('all_sessions'). These core datasets come in different sizes, and, each of them has a variant that was intentionally made faulty (totally riddled with errors and inconsistencies). This suite of tables is useful for testing with packages that focus on data validation and data documentation.

Simulation of segments shared identical-by-descent (IBD) by pedigree members. Using sex specific recombination rates along the human genome (Halldorsson et al. (2019) <doi:10.1126/science.aau1043>), phased chromosomes are simulated for all pedigree members. Applications include calculation of realised relatedness coefficients and IBD segment distributions. ibdsim2 is part of the pedsuite collection of packages for pedigree analysis. A detailed presentation of the pedsuite', including a separate chapter on ibdsim2', is available in the book Pedigree analysis in R (Vigeland, 2021, ISBN:9780128244302). A Shiny app for visualising and comparing IBD distributions is available at <https://magnusdv.shinyapps.io/ibdsim2-shiny/>.

The Importance Index (I.I.) can determine the loss and solution sources for a system in certain knowledge areas (e.g., agronomy), when production (e.g., fruits) is known (Demolin-Leite, 2021). Events (e.g., agricultural pest) can have different magnitudes (numerical measurements), frequencies, and distributions (aggregate, random, or regular) of event occurrence, and I.I. bases in this triplet (Demolin-Leite, 2021) <https://cjascience.com/index.php/CJAS/article/view/1009/1319>. Usually, the higher the magnitude and frequency of aggregated distribution, the greater the problem or the solution (e.g., natural enemies versus pests) for the system (Demolin-Leite, 2021). However, the final production of the system is not always known or is difficult to determine (e.g., degraded area recovery). A derivation of the I.I. is the percentage of Importance Index-Production Unknown (% I.I.-PU) that can detect the loss or solution sources, when production is unknown for the system (Demolin-Leite, 2024) <DOI:10.1590/1519-6984.253218>.

Mining informative genes with certain biological meanings are important for clinical diagnosis of disease and discovery of disease mechanisms in plants and animals. This process involves identification of relevant genes and removal of redundant genes as much as possible from a whole gene set. This package selects the informative genes related to a specific trait using gene expression dataset. These trait specific genes are considered as informative genes. This package returns the informative gene set from the high dimensional gene expression data using a combination of methods SVM and MRMR (for feature selection) with bootstrapping procedure.

Evaluating if values of vectors are within different open/closed intervals (`x %[]% c(a, b)`), or if two closed intervals overlap (`c(a1, b1) %[]o[]% c(a2, b2)`). Operators for negation and directional relations also implemented.

This package provides methods for testing the equality of dependent intraclass correlation coefficients (ICCs) estimated using linear mixed-effects models. Several of the implemented approaches are based on the work of Donner and Zou (2002) <doi:10.1111/1467-9884.00324>.

The Iterative Cumulative Sum of Squares (ICSS) algorithm by Inclan/Tiao (1994) <https://www.jstor.org/stable/2290916> detects multiple change points, i.e. structural break points, in the variance of a sequence of independent observations. For series of moderate size (i.e. 200 observations and beyond), the ICSS algorithm offers results comparable to those obtained by a Bayesian approach or by likelihood ration tests, without the heavy computational burden required by these approaches.

Semiparametric regression models on the cumulative incidence function for interval-censored competing risks data as described in Bakoyannis, Yu, & Yiannoutsos (2017) /doi10.1002/sim.7350 and the models with missing event types as described in Park, Bakoyannis, Zhang, & Yiannoutsos (2021) \doi10.1093/biostatistics/kxaa052. The proportional subdistribution hazards model (Fine-Gray model), the proportional odds model, and other models that belong to the class of semiparametric generalized odds rate transformation models.

This package provides utilities to retrieve and manage ICD-10 code descriptions from Excel files. Supports vectors, data frame columns, and association rule outputs (e.g., arules objects) that require mapping to ICD-10 descriptions. Designed to simplify processing of healthcare datasets.

This package provides a joint mixture model has been developed by Majumdar et al. (2025) <doi:10.48550/arXiv.2412.17511> that integrates information from gene expression data and methylation data at the modelling stage to capture their inherent dependency structure, enabling simultaneous identification of differentially methylated cytosine-guanine dinucleotide (CpG) sites and differentially expressed genes. The model leverages a joint likelihood function that accounts for the nested structure in the data, with parameter estimation performed using an expectation-maximisation algorithm.

This package provides tools for estimating incidence from biomarker data in cross- sectional surveys, and for calibrating tests for recent infection. Implements and extends the method of Kassanjee et al. (2012) <doi:10.1097/EDE.0b013e3182576c07>.

This package provides a collection of Irucka Embry's miscellaneous USGS data sets (USGS Parameter codes with fixed values, USGS global time zone codes, and US Air Force Global Engineering Weather Data). Irucka created these data sets while a Cherokee Nation Technology Solutions (CNTS) United States Geological Survey (USGS) Contractor and/or USGS employee.

Programmatic access to NSIDC's sea ice concentration CDR <https://nsidc.org/data/g02202> via ERDAPP server and Sea Ice index <https://nsidc.org/data/g02135>. Supports caching results and optional fixes for some inconsistencies of the raw files.

We provide the collection of data-sets used in the book An Introduction to Statistical Learning with Applications in R'.

This package provides a novel machine learning method for plant viruses diagnostic using genome sequencing data. This package includes three different machine learning models, random forest, XGBoost, and elastic net, to train and predict mapped genome samples. Mappability profile and unreliable regions are introduced to the algorithm, and users can build a mappability profile from scratch with functions included in the package. Plotting mapped sample coverage information is provided.

Nicely formatted frequency tables and contingency tables (1-way, 2-way, 3-way and 4-way tables), that can easily be exported to HTML or Office documents. Designed to work with pipes.

Two functions for running and then post-estimating an Interrupted Time Series Analysis model. This is a solution for running time series analyses on temporally short data. See English (2019) The its.analysis R package - Modelling short time series data <https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3398189> for an overview of the method.