This package provides Shiny widgets and theme that support a Library Computer Access/Retrieval System (LCARS) aesthetic for Shiny apps. The package also includes functions for adding a minimal LCARS theme to static ggplot2 graphs. More details about LCARS can be found at <https://en.wikipedia.org/wiki/LCARS>.

Identifying latent genetic interactions in genome-wide association studies using the Latent Interaction Testing (LIT) framework. LIT is a flexible kernel-based approach that leverages information across multiple traits to detect latent genetic interactions without specifying or observing the interacting variable (e.g., environment). LIT accepts standard PLINK files as inputs to analyze large genome-wide association studies.

Fits and tests logistic joinpoint models.

Extracts and creates an analysis pipeline for the JSON data files from Brain Sense sessions using Medtronic's Deep Brain Stimulation surgery electrode implants.

Back-end connections to LattE (<https://www.math.ucdavis.edu/~latte/>) for counting lattice points and integration inside convex polytopes and 4ti2 (<http://www.4ti2.de/>) for algebraic, geometric, and combinatorial problems on linear spaces and front-end tools facilitating their use in the R ecosystem.

Fits structural equation modeling via penalized likelihood.

R interface for working with nanometer scale secondary ion mass spectrometry (NanoSIMS) data exported from Look at NanoSIMS.

Estimate haplotypic or composite pairwise linkage disequilibrium (LD) in polyploids, using either genotypes or genotype likelihoods. Support is provided to estimate the popular measures of LD: the LD coefficient D, the standardized LD coefficient D', and the Pearson correlation coefficient r. All estimates are returned with corresponding standard errors. These estimates and standard errors can then be used for shrinkage estimation. The main functions are ldfast(), ldest(), mldest(), sldest(), plot.lddf(), format_lddf(), and ldshrink(). Details of the methods are available in Gerard (2021a) <doi:10.1111/1755-0998.13349> and Gerard (2021b) <doi:10.1038/s41437-021-00462-5>.

This package provides methods for the interpolation of large spatial datasets. This package uses a basis function approach that provides a surface fitting method that can approximate standard spatial data models. Using a large number of basis functions allows for estimates that can come close to interpolating the observations (a spatial model with a small nugget variance.) Moreover, the covariance model for this method can approximate the Matern covariance family but also allows for a multi-resolution model and supports efficient computation of the profile likelihood for estimating covariance parameters. This is accomplished through compactly supported basis functions and a Markov random field model for the basis coefficients. These features lead to sparse matrices for the computations and this package makes of the R spam package for sparse linear algebra. An extension of this version over previous ones ( < 5.4 ) is the support for different geometries besides a rectangular domain. The Markov random field approach combined with a basis function representation makes the implementation of different geometries simple where only a few specific R functions need to be added with most of the computation and evaluation done by generic routines that have been tuned to be efficient. One benefit of this package's model/approach is the facility to do unconditional and conditional simulation of the field for large numbers of arbitrary points. There is also the flexibility for estimating non-stationary covariances and also the case when the observations are a linear combination (e.g. an integral) of the spatial process. Included are generic methods for prediction, standard errors for prediction, plotting of the estimated surface and conditional and unconditional simulation. See the LatticeKrigRPackage GitHub repository for a vignette of this package. Development of this package was supported in part by the National Science Foundation Grant 1417857 and the National Center for Atmospheric Research.

This package provides a bunch of algorithms based on linear programming for estimating, under the homogeneity hypothesis, RxC ecological contingency tables (or vote transition matrices) using mainly aggregate data (from voting units). References: Pavà a and Romero (2024) <doi:10.1177/00491241221092725>. Pavà a and Romero (2024) <doi:10.1093/jrsssa/qnae013>. Pavà a (2023) <doi:10.1007/s43545-023-00658-y>. Pavà a (2024) <doi:10.1080/0022250X.2024.2423943>. Pavà a (2024) <doi:10.1177/07591063241277064>. Pavà a and Penadés (2024). A bottom-up approach for ecological inference. Romero, Pavà a, Martà n and Romero (2020) <doi:10.1080/02664763.2020.1804842>. Acknowledgements: The authors wish to thank Consellerà a de Educación, Cultura, Universidades y Empleo, Generalitat Valenciana (grants AICO/2021/257, CIAICO/2023/031) and MICIU/AEI/10.13039/501100011033/FEDER, UE (grant PID2021-128228NB-I00) for supporting this research.

Lights Out is a puzzle game consisting of a grid of lights that are either on or off. Pressing any light will toggle it and its adjacent lights. The goal of the game is to switch all the lights off. This package provides an interface to play the game on different board sizes, both through the command line or with a visual application. Puzzles can also be solved using the automatic solver included. View a demo online at <https://daattali.com/shiny/lightsout/>.

Automated analysis and modeling of longitudinal omics data (e.g. breath metabolomics') using generalized spline mixed effect models. Including automated filtering of noise parameters and determination of breakpoints.

Plots empty Lexis grids, adds lifelines and highlights certain areas of the grid, like cohorts and age groups.

The Length-Biased Power Garima distribution for computes the probability density, the cumulative density distribution and the quantile function of the distribution, and generates sample values with random variables based on Kittipong and Sirinapa(2021)<DOI: 10.14456/sjst-psu.2021.89>.

Insieme di funzioni di supporto al volume "Laboratorio di Statistica con R", Iacus-Masarotto, MacGraw-Hill Italia, 2006. This package contains sets of functions defined in "Laboratorio di Statistica con R", Iacus-Masarotto, MacGraw-Hill Italia, 2006. Function names and docs are in italian as well.

The log4r package is meant to provide a fast, lightweight, object-oriented approach to logging in R based on the widely-emulated log4j system and etymology.

This package provides a collection of colour palettes inspired by some of our dearest butterfly species. This package provides continuous and categorical palettes, including some colour blind friendly options.

Mixture modelling of one-dimensional data using combinations of left-truncated Gamma, Weibull, and Lognormal Distributions. Blostein, Martin & Miljkovic, Tatjana. (2019) <doi:10.1016/j.insmatheco.2018.12.001>.

"Learning with Subset Stacking" is a supervised learning algorithm that is based on training many local estimators on subsets of a given dataset, and then passing their predictions to a global estimator. You can find the details about LESS in our manuscript at <arXiv:2112.06251>.

Estimation of Latent Order Logistic (LOLOG) Models for Networks. LOLOGs are a flexible and fully general class of statistical graph models. This package provides functions for performing MOM, GMM and variational inference. Visual diagnostics and goodness of fit metrics are provided. See Fellows (2018) <doi:10.48550/arXiv.1804.04583> for a detailed description of the methods.

Simplex optimization algorithms as firstly proposed by Spendley et al. (1962) <doi:10.1080/00401706.1962.10490033> and later modified by Nelder and Mead (1965) <doi:10.1093/comjnl/7.4.308> for laboratory and manufacturing processes. The package also provides tools for graphical representation of the simplexes and some example response surfaces that are useful in illustrating the optimization process.

Calculate point estimates of and valid confidence intervals for longitudinal summaries of nonparametric, algorithm-agnostic variable importance measures. For more details, see Williamson et al. (2024) <doi:10.48550/arXiv.2311.01638>.

This package provides a Low Rank Correction Variational Bayesian algorithm for high-dimensional multi-source heterogeneous quantile linear models. More details have been written up in a paper submitted to the journal Statistics in Medicine, and the details of variational Bayesian methods can be found in Ray and Szabo (2021) <doi:10.1080/01621459.2020.1847121>. It simultaneously performs parameter estimation and variable selection. The algorithm supports two model settings: (1) local models, where variable selection is only applied to homogeneous coefficients, and (2) global models, where variable selection is also performed on heterogeneous coefficients. Two forms of parameter estimation are output: one is the standard variational Bayesian estimation, and the other is the variational Bayesian estimation corrected with low-rank adjustment.

Estimates a lognormal-Pareto mixture by means of the Expectation-Conditional-Maximization-Either algorithm and by maximizing the profile likelihood function. A likelihood ratio test for discriminating between lognormal and Pareto tail is also implemented. See Bee, M. (2022) <doi:10.1007/s11634-022-00497-4>.