MerfishData is an ExperimentHub package that serves publicly available datasets obtained with Multiplexed Error-Robust Fluorescence in situ Hybridization (MERFISH). MERFISH is a massively multiplexed single-molecule imaging technology capable of simultaneously measuring the copy number and spatial distribution of hundreds to tens of thousands of RNA species in individual cells. The scope of the package is to provide MERFISH data for benchmarking and analysis.

# NetActivity enables to compute gene set scores from previously trained sparsely-connected autoencoders. The package contains a function to prepare the data (`prepareSummarizedExperiment`) and a function to compute the gene set scores (`computeGeneSetScores`). The package `NetActivityData` contains different pre-trained models to be directly applied to the data. Alternatively, the users might use the package to compute gene set scores using custom models.

This package provides functions for creating, modifying, and displaying bitmaps including printing them in the terminal. There is a special emphasis on monochrome bitmap fonts and their glyphs as well as colored pixel art/sprites. Provides native read/write support for the hex and yaff bitmap font formats and if monobit <https://github.com/robhagemans/monobit> is installed can also read/write several additional bitmap font formats.

This package provides a modified boxplot with a new fence coefficient determined by Lin et al. (2025). The traditional fence coefficient k=1.5 in Tukey's boxplot is replaced by a coefficient based on Chauvenet's criterion, as described in their formula (9). The new boxplot can be implemented in base R with function chau_boxplot(), and in ggplot2 with function geom_chau_boxplot().

Functionality to perform adaptive multi-wave sampling for efficient chart validation. Code allows one to define strata, adaptively sample using several types of confidence bounds for the quantity of interest (Lai's confidence bands, Bayesian credible intervals, normal confidence intervals), and sampling strategies (random sampling, stratified random sampling, Neyman's sampling, see Neyman (1934) <doi:10.2307/2342192> and Neyman (1938) <doi:10.1080/01621459.1938.10503378>).

This package provides methods for computing and visualizing wildfire ignition exposure and directional vulnerability that are published in a series of scientific publications are automated by the functions in this package. See Beverly et al. (2010) <doi:10.1071/WF09071>, Beverly et al. (2021) <doi:10.1007/s10980-020-01173-8>, and Beverly and Forbes (2023) <doi:10.1007/s11069-023-05885-3> for background and methodology.

Geographically Dependent Individual Level Models (GDILMs) within the Susceptible-Exposed-Infectious-Recovered-Susceptible (SEIRS) framework are applied to model infectious disease transmission, incorporating reinfection dynamics. This package employs a likelihood based Monte Carlo Expectation Conditional Maximization (MCECM) algorithm for estimating model parameters. It also provides tools for GDILM fitting, parameter estimation, AIC calculation on real pandemic data, and simulation studies customized to user-defined model settings.

Nonparametric density estimation for (hyper)spherical data by means of a parametrically guided kernel estimator (adaptation of the method of Hjort and Glad (1995) <doi:10.1214/aos/1176324627> to the spherical setting). The package also allows the data-driven selection of the smoothing parameter and the representation of the estimated density for circular and spherical data. Estimators of the density without guide can also be obtained.

Offers a comprehensive approach for analysing stratified 2x2 contingency tables. It facilitates the calculation of odds ratios, 95% confidence intervals, and conducts chi-squared, Cochran-Mantel-Haenszel, Mantel-Haenszel, and Breslow-Day-Tarone tests. The package is particularly useful in fields like epidemiology and social sciences where stratified analysis is essential. The package also provides interpretative insights into the results, aiding in the understanding of statistical outcomes.

Reliability and agreement analyses often have limited software support. Therefore, this package was created to make agreement and reliability analyses easier for the average researcher. The functions within this package include simple tests of agreement, agreement analysis for nested and replicate data, and provide robust analyses of reliability. In addition, this package contains a set of functions to help when planning studies looking to assess measurement agreement.

Presents a series of molecular and genetic routines in the R environment with the aim of assisting in analytical pipelines before and after the use of asreml or another library to perform analyses such as Genomic Selection or Genome-Wide Association Analyses. Methods and examples are described in Gezan, Oliveira, Galli, and Murray (2022) <https://asreml.kb.vsni.co.uk/wp-content/uploads/sites/3/ASRgenomics_Manual.pdf>.

Downloads wrangled Colombian socioeconomic, geospatial,population and climate data from DANE <https://www.dane.gov.co/> (National Administrative Department of Statistics) and IDEAM (Institute of Hydrology, Meteorology and Environmental Studies). It solves the problem of Colombian data being issued in different web pages and sources by using functions that allow the user to select the desired database and download it without having to do the exhausting acquisition process.

Creation and selection of (Advanced) Coupled Matrix and Tensor Factorization (ACMTF) and ACMTF-Regression (ACMTF-R) models. Selection of the optimal number of components can be done using ACMTF_modelSelection() and ACMTFR_modelSelection()'. The CMTF and ACMTF methods were originally described by Acar et al., 2011 <doi:10.48550/arXiv.1105.3422> and Acar et al., 2014 <doi:10.1186/1471-2105-15-239>, respectively.

Apply tests of multiple comparisons based on studentized midrange and range distributions. The tests are: Tukey Midrange ('TM test), Student-Newman-Keuls Midrange ('SNKM test), Means Grouping Midrange ('MGM test) and Means Grouping Range ('MGR test). The first two tests were published by Batista and Ferreira (2020) <doi:10.1590/1413-7054202044008020>. The last two were published by Batista and Ferreira (2023) <doi:10.28951/bjb.v41i4.640>.

Creativity research involves the need to score open-ended problems. Usually done by humans, automatic scoring using AI becomes more and more accurate. This package provides a simple interface to the Open Scoring API <https://openscoring.du.edu/docs>, leading creativity scoring technology by Organiscak et al. (2023) <doi:10.1016/j.tsc.2023.101356>. With it, you can score your own data directly from an R script.

This package provides seamless access to the QGIS (<https://qgis.org>) processing toolbox using the standalone qgis_process command-line utility. Both native and third-party (plugin) processing providers are supported. Beside referring data sources from file, also common objects from sf', terra and stars are supported. The native processing algorithms are documented by QGIS.org (2024) <https://docs.qgis.org/latest/en/docs/user_manual/processing_algs/>.

This package provides methods for managing under- and over-enrollment in Simon's Two-Stage Design are offered by providing adaptive threshold adjustments and sample size recalibration. It also includes post-inference analysis tools to support clinical trial design and evaluation. The package is designed to enhance flexibility and accuracy in trial design, ensuring better outcomes in oncology and other clinical studies. Yunhe Liu, Haitao Pan (2024). Submitted.

This package provides tools for working with Type S (Sign) and Type M (Magnitude) errors, as proposed in Gelman and Tuerlinckx (2000) <doi:10.1007/s001800000040> and Gelman & Carlin (2014) <doi:10.1177/1745691614551642>. In addition to simply calculating the probability of Type S/M error, the package includes functions for calculating these errors across a variety of effect sizes for comparison, and recommended sample size given "tolerances" for Type S/M errors. To improve the speed of these calculations, closed forms solutions for the probability of a Type S/M error from Lu, Qiu, and Deng (2018) <doi:10.1111/bmsp.12132> are implemented. As of 1.0.0, this includes support only for simple research designs. See the package vignette for a fuller exposition on how Type S/M errors arise in research, and how to analyze them using the type of design analysis proposed in the above papers.

The cfToolsData package supplies the data for the cfTools package. It contains two pre-trained deep neural network (DNN) models for the cfSort function. Additionally, it includes the shape parameters of beta distribution characterizing methylation markers associated with four tumor types for the CancerDetector function, as well as the parameters characterizing methylation markers specific to 29 primary human tissue types for the cfDeconvolve function.

This package contains the data for the paper by L. David et al. in PNAS 2006 (PMID 16569694): 8 CEL files of Affymetrix genechips, an ExpressionSet object with the raw feature data, a probe annotation data structure for the chip and the yeast genome annotation (GFF file) that was used. In addition, some custom-written analysis functions are provided, as well as R scripts in the scripts directory.

Rank results by confident effect sizes, while maintaining False Discovery Rate and False Coverage-statement Rate control. Topconfects is an alternative presentation of TREAT results with improved usability, eliminating p-values and instead providing confidence bounds. The main application is differential gene expression analysis, providing genes ranked in order of confident log2 fold change, but it can be applied to any collection of effect sizes with associated standard errors.

LLVM is a compiler infrastructure designed for compile-time, link-time, runtime, and idle-time optimization of programs from arbitrary programming languages. It currently supports compilation of C and C++ programs, using front-ends derived from GCC 4.0.1. A new front-end for the C family of languages is in development. The compiler infrastructure includes mirror sets of programming tools as well as libraries with equivalent functionality.

Adaptive and Robust Transfer Learning (ART) is a flexible framework for transfer learning that integrates information from auxiliary data sources to improve model performance on primary tasks. It is designed to be robust against negative transfer by including the non-transfer model in the candidate pool, ensuring stable performance even when auxiliary datasets are less informative. See the paper, Wang, Wu, and Ye (2023) <doi:10.1002/sta4.582>.

This package provides a set of tools for evaluating clustering robustness using proportion of ambiguously clustered pairs (Senbabaoglu et al. (2014) <doi:10.1038/srep06207>), as well as similarity across methods and method stability using element-centric clustering comparison (Gates et al. (2019) <doi:10.1038/s41598-019-44892-y>). Additionally, this package enables stability-based parameter assessment for graph-based clustering pipelines typical in single-cell data analysis.