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Perform association tests using generalized linear mixed models (GLMMs) in genome-wide association studies (GWAS) and sequencing association studies. First, GMMAT fits a GLMM with covariate adjustment and random effects to account for population structure and familial or cryptic relatedness. For GWAS, GMMAT performs score tests for each genetic variant as proposed in Chen et al. (2016) <DOI:10.1016/j.ajhg.2016.02.012>. For candidate gene studies, GMMAT can also perform Wald tests to get the effect size estimate for each genetic variant. For rare variant analysis from sequencing association studies, GMMAT performs the variant Set Mixed Model Association Tests (SMMAT) as proposed in Chen et al. (2019) <DOI:10.1016/j.ajhg.2018.12.012>, including the burden test, the sequence kernel association test (SKAT), SKAT-O and an efficient hybrid test of the burden test and SKAT, based on user-defined variant sets.
Automated General-to-Specific (GETS) modelling of the mean and variance of a regression, and indicator saturation methods for detecting and testing for structural breaks in the mean, see Pretis, Reade and Sucarrat (2018) <doi:10.18637/jss.v086.i03> for an overview of the package. In advanced use, the estimator and diagnostics tests can be fully user-specified, see Sucarrat (2021) <doi:10.32614/RJ-2021-024>.
This package provides ggplot2 equivalents of fixest::coefplot() and fixest::iplot(), for producing nice coefficient plots and interaction plots. Enables some additional functionality and convenience features, including grouped multi-'fixest object faceting and programmatic updates to existing plots (e.g., themes and aesthetics).
Selective Sweep can be calculated by five significant Population Genetics Statistics such as "Pi", "Wattersons_theta", "Tajima_D", "Kelly_ZnS" and "Omega" Statistics in specified chromosomal region. It has been developed by using the concept of "Kern" and "Schrider" (2018)<doi:10.1534/g3.118.200262>.
This package implements a flexible nonlinear modelling framework for nonstationary generalized extreme value analysis in hydroclimatology following Cannon (2010) <doi:10.1002/hyp.7506>.
This package provides basic distribution functions for a generalized logistic distribution proposed by Rathie and Swamee (2006) <https://www.rroij.com/open-access/on-new-generalized-logistic-distributions-and-applicationsbarreto-fhs-mota-jma-and-rathie-pn-.pdf>. It also has an interactive RStudio plot for better guessing dynamically of initial values for ease of included optimization and simulating.
This package provides functions for survey data including svydesign objects from the survey package that call ggplot2 to make bar charts, histograms, boxplots, and hexplots of survey data.
Helper to add insets based on geom_sf() from ggplot2'. This package gives you a drop-in replacement for geom_sf() that supports adding a zoomed inset map without having to create and embed a separate plot.
This package provides a ggplot2 extension that enables robust image grobs in panels and theme elements.
This package provides a collection of enhancements to ggplot2', with a focus on creating Universally Designed, accessible graphs easily and quickly.
Maximum likelihood estimation, random values generation, density computation and other functions for the exponential-Poisson generalised exponential-Poisson and Poisson-exponential distributions. References include: Rodrigues G. C., Louzada F. and Ramos P. L. (2018). "Poisson-exponential distribution: different methods of estimation". Journal of Applied Statistics, 45(1): 128--144. <doi:10.1080/02664763.2016.1268571>. Louzada F., Ramos, P. L. and Ferreira, H. P. (2020). "Exponential-Poisson distribution: estimation and applications to rainfall and aircraft data with zero occurrence". Communications in Statistics--Simulation and Computation, 49(4): 1024--1043. <doi:10.1080/03610918.2018.1491988>. Barreto-Souza W. and Cribari-Neto F. (2009). "A generalization of the exponential-Poisson distribution". Statistics and Probability Letters, 79(24): 2493--2500. <doi:10.1016/j.spl.2009.09.003>.
This package provides function to apply "Group sequential enrichment design incorporating subgroup selection" (GSED) method proposed by Magnusson and Turnbull (2013) <doi:10.1002/sim.5738>.
An implementation of Gini-based weighting approaches in constructing composite indicators, providing functionalities for normalization, aggregation, and ranking comparison.
Simulating composite endpoints with recurrent and terminal events under staggered entry, and for constructing one- and two-sample group sequential test statistics and monitoring boundaries based on the mean frequency function. Details will be available in an upcoming publication.
This package provides multiple palettes based on pride flags with tailored themes.
This package provides a high performance interface to the Global Biodiversity Information Facility, GBIF'. In contrast to rgbif', which can access small subsets of GBIF data through web-based queries to a central server, gbifdb provides enhanced performance for R users performing large-scale analyses on servers and cloud computing providers, providing full support for arbitrary SQL or dplyr operations on the complete GBIF data tables (now over 1 billion records, and over a terabyte in size). gbifdb accesses a copy of the GBIF data in parquet format, which is already readily available in commercial computing clouds such as the Amazon Open Data portal and the Microsoft Planetary Computer, or can be accessed directly without downloading, or downloaded to any server with suitable bandwidth and storage space. The high-performance techniques for local and remote access are described in <https://duckdb.org/why_duckdb> and <https://arrow.apache.org/docs/r/articles/fs.html> respectively.
Splits date and time of day components from continuous datetime objects, then plots them using grammar of graphics ('ggplot2'). Plots can also be decorated with solar cycle information (e.g., sunset, sunrise, etc.). This is useful for visualising data that are associated with the solar cycle.
Implementation of a common set of punctual solutions for Cooperative Game Theory.
Convert general transit feed specification (GTFS) data to global positioning system (GPS) records in data.table format. It also has some functions to subset GTFS data in time and space and to convert both representations to simple feature format.
Given exposure and survival time series as well as parameter values, GUTS allows for the fast calculation of the survival probabilities as well as the logarithm of the corresponding likelihood (see Albert, C., Vogel, S. and Ashauer, R. (2016) <doi:10.1371/journal.pcbi.1004978>).
Represents generalized geometric ellipsoids with the "(U,D)" representation. It allows degenerate and/or unbounded ellipsoids, together with methods for linear and duality transformations, and for plotting. Thus ellipsoids are naturally extended to include lines, hyperplanes, points, cylinders, etc. This permits exploration of a variety to statistical issues that can be visualized using ellipsoids as discussed by Friendly, Fox & Monette (2013), Elliptical Insights: Understanding Statistical Methods Through Elliptical Geometry <doi:10.1214/12-STS402>.
Regression using GMDH algorithms from Prof. Alexey G. Ivakhnenko. Group Method of Data Handling (GMDH), or polynomial neural networks, is a family of inductive algorithms that performs gradually complicated polynomial models and selecting the best solution by an external criterion. In other words, inductive GMDH algorithms give possibility finding automatically interrelations in data, and selecting an optimal structure of model or network. The package includes GMDH Combinatorial, GMDH MIA (Multilayered Iterative Algorithm), GMDH GIA (Generalized Iterative Algorithm) and GMDH Combinatorial with Active Neurons.
Dependency-free, ultra fast calculation of geodesic distances. Includes the reference nanometre-accuracy geodesic distances of Karney (2013) <doi:10.1007/s00190-012-0578-z>, as used by the sf package, as well as Haversine and Vincenty distances. Default distance measure is the "Mapbox cheap ruler" which is generally more accurate than Haversine or Vincenty for distances out to a few hundred kilometres, and is considerably faster. The main function accepts one or two inputs in almost any generic rectangular form, and returns either matrices of pairwise distances, or vectors of sequential distances.
Estimates grid type bivariate copula functions, calculates some association measures and provides several copula graphics.