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Simply and efficiently simulates (i) variants from reference genomes and (ii) reads from both Illumina <https://www.illumina.com/> and Pacific Biosciences (PacBio) <https://www.pacb.com/> platforms. It can either read reference genomes from FASTA files or simulate new ones. Genomic variants can be simulated using summary statistics, phylogenies, Variant Call Format (VCF) files, and coalescent simulationsâ the latter of which can include selection, recombination, and demographic fluctuations. jackalope can simulate single, paired-end, or mate-pair Illumina reads, as well as PacBio reads. These simulations include sequencing errors, mapping qualities, multiplexing, and optical/polymerase chain reaction (PCR) duplicates. Simulating Illumina sequencing is based on ART by Huang et al. (2012) <doi:10.1093/bioinformatics/btr708>. PacBio sequencing simulation is based on SimLoRD by Stöcker et al. (2016) <doi:10.1093/bioinformatics/btw286>. All outputs can be written to standard file formats.
The jscore() function in the package calculates the J-Score metric between two clustering assignments. The score is designed to address some problems with existing common metrics such as problem of matching. The details of J-score is described in Ahmadinejad and Liu. (2021) <arXiv:2109.01306>.
Procedures for joint detection of changes in both expectation and variance in univariate sequences. Performs a statistical test of the null hypothesis of the absence of change points. In case of rejection performs an algorithm for change point detection. Reference - Bivariate change point detection - joint detection of changes in expectation and variance, Scandinavian Journal of Statistics, DOI 10.1111/sjos.12547.
Fit survival data and perform dynamic prediction under joint frailty-copula models for tumour progression and death. Likelihood-based methods are employed for estimating model parameters, where the baseline hazard functions are modeled by the cubic M-spline or the Weibull model. The methods are applicable for meta-analytic data containing individual-patient information from several studies. Survival outcomes need information on both terminal event time (e.g., time-to-death) and non-terminal event time (e.g., time-to-tumour progression). Methodologies were published in Emura et al. (2017) <doi:10.1177/0962280215604510>, Emura et al. (2018) <doi:10.1177/0962280216688032>, Emura et al. (2020) <doi:10.1177/0962280219892295>, Shinohara et al. (2020) <doi:10.1080/03610918.2020.1855449>, Wu et al. (2020) <doi:10.1007/s00180-020-00977-1>, and Emura et al. (2021) <doi:10.1177/09622802211046390>. See also the book of Emura et al. (2019) <doi:10.1007/978-981-13-3516-7>. Survival data from ovarian cancer patients are also available.
Shared parameter models for the joint modeling of longitudinal and time-to-event data.
Jointly estimates two-group means and covariances for matrix-variate data and calculates test statistics. This package implements the algorithms defined in Hornstein, Fan, Shedden, and Zhou (2018) <doi:10.1080/01621459.2018.1429275>.
This package provides tools for using the API of e-Stat (<https://www.e-stat.go.jp/>), a portal site for Japanese government statistics. Includes functions for automatic query generation, data collection and formatting.
An estimation method that can use computer simulations to approximate maximum-likelihood estimates even when the likelihood function can not be evaluated directly. It can be applied whenever it is feasible to conduct many simulations, but works best when the data is approximately Poisson distributed. It was originally designed for demographic inference in evolutionary biology (Naduvilezhath et al., 2011 <doi:10.1111/j.1365-294X.2011.05131.x>, Mathew et al., 2013 <doi:10.1002/ece3.722>). It has optional support for conducting coalescent simulation using the coala package.
Create regression tables from generalized linear model(GLM), generalized estimating equation(GEE), generalized linear mixed-effects model(GLMM), Cox proportional hazards model, survey-weighted generalized linear model(svyglm) and survey-weighted Cox model results for publication.
Generates interactive Jellyfish plots to visualize spatiotemporal tumor evolution by integrating sample and phylogenetic trees into a unified plot. This approach provides an intuitive way to analyze tumor heterogeneity and evolution over time and across anatomical locations. The Jellyfish plot visualization design was first introduced by Lahtinen, Lavikka, et al. (2023, <doi:10.1016/j.ccell.2023.04.017>). This package also supports visualizing ClonEvol results, a tool developed by Dang, et al. (2017, <doi:10.1093/annonc/mdx517>), for analyzing clonal evolution from multi-sample sequencing data. The clonevol package is not available on CRAN but can be installed from its GitHub repository (<https://github.com/hdng/clonevol>).
This package provides functions for grid square codes in Japan (<https://www.stat.go.jp/english/data/mesh/index.html>). Generates the grid square codes from longitude/latitude, geometries, and the grid square codes of different scales, and vice versa.
This package provides tools are provided to streamline Bayesian analyses in JAGS using the jagsUI package. Included are functions for extracting output in simpler format, functions for streamlining assessment of convergence, and functions for producing summary plots of output. Also included is a function that provides a simple template for running JAGS from R'. Referenced materials can be found at <DOI:10.1214/ss/1177011136>.
This package contains procedures to estimate the nine condensed Jacquard genetic identity coefficients (Jacquard, 1974) <doi:10.1007/978-3-642-88415-3> by constrained least squares (Graffelman et al., 2024) <doi:10.1101/2024.03.25.586682> and by the method of moments (Csuros, 2014) <doi:10.1016/j.tpb.2013.11.001>. These procedures require previous estimation of the allele frequencies. Functions are supplied that estimate relationship parameters that derive from the Jacquard coefficients, such as individual inbreeding coefficients and kinship coefficients.
The Impact Factor of a journal reported by Journal Citation Reports ('JCR') of Clarivate Analytics is provided. The impact factor is available for those journals only that were included Journal Citation Reports JCR'.
This package provides a modern, tidy interface to the Jira REST API for both Jira Cloud and Jira Server / Data Center. Authenticate once, query issues with the Jira Query Language (JQL), and retrieve projects, fields, dashboards and more as tibbles. Built on httr2 with automatic pagination, informative errors and support for API tokens and personal access tokens.
Customized R Markdown templates for authoring articles for Journal of Data Science.
Individual based simulations of hybridizing populations, where the accumulation of junctions is tracked. Furthermore, mathematical equations are provided to verify simulation outcomes. Both simulations and mathematical equations are based on Janzen (2018, <doi:10.1101/058107>) and Janzen (2022, <doi:10.1111/1755-0998.13519>).
Since the reference management software (such as Zotero', Mendeley') exports Bib file journal abbreviation is not detailed enough, the journalabbr package only abbreviates the journal field of Bib file, and then outputs a new Bib file for generating reference format with journal abbreviation on other software (such as texstudio'). The abbreviation table is from JabRef'. At the same time, Shiny application is provided to generate thebibliography', a reference format that can be directly used for latex paper writing based on Rmd files.
This package provides functions to justify alpha levels for statistical hypothesis tests by avoiding Lindley's paradox, or by minimizing or balancing error rates. For more information about the package please read the following: Maier & Lakens (2021) <doi:10.31234/osf.io/ts4r6>).
Proposes a coarse-to-fine optimization of a recommending system based on deep-neural networks using tensorflow'.
This package provides diagnostic tools for understanding and debugging data frame joins. Analyzes key columns before joining to detect duplicates, mismatches, encoding issues, and other common problems. Explains unexpected row count changes and provides safe join wrappers with cardinality enforcement. Concepts and diagnostics build on tidy data principles as described in Wickham (2014) <doi:10.18637/jss.v059.i10>.
Maximum likelihood estimation for the semiparametric joint modeling of survival and longitudinal data. Refer to the Journal of Statistical Software article: <doi:10.18637/jss.v093.i02>.
These functions calculate the taxonomic measures presented in Miranda-Esquivel (2016). The package introduces Jack-knife resampling in evolutionary distinctiveness prioritization analysis, as a way to evaluate the support of the ranking in area prioritization, and the persistence of a given area in a conservation analysis. The algorithm is described in: Miranda-Esquivel, D (2016) <DOI:10.1007/978-3-319-22461-9_11>.
This package provides a long-term forecast model called "Jubilee-Tectonic model" is implemented to forecast future returns of the U.S. stock market, Treasury yield, and gold price. The five-factor model forecasts the 10-year and 20-year future equity returns with high R-squared above 80 percent. It is based on linear growth and mean reversion characteristics in the U.S. stock market. This model also enhances the CAPE model by introducing the hypothesis that there are fault lines in the historical CAPE, which can be calibrated and corrected through statistical learning. In addition, it contains a module for business cycles, optimal interest rate, and recession forecasts.