It provides functions to design historical controlled trials with survival outcome by group sequential method. The options for interim look boundaries are efficacy only, efficacy & futility or futility only. It also provides the function to monitor the trial for any unplanned look. The package is based on Jianrong Wu, Xiaoping Xiong (2016) <doi:10.1002/pst.1756> and Jianrong Wu, Yimei Li (2020) <doi:10.1080/10543406.2019.1684305>.

An implementation of the nonnegative garrote method that incorporates hierarchical relationships among variables. The core function, HiGarrote(), offers an automated approach for analyzing experiments while respecting hierarchical structures among effects. For methodological details, refer to Yu and Joseph (2025) <doi:10.1080/00224065.2025.2513508>. This work is supported by U.S. National Science Foundation grant DMS-2310637.

Health Calculator helps to find different parameters like basal metabolic rate, body mass index etc. related to fitness and health of a person.

Build better balance in causal inference models. halfmoon helps you assess propensity score models for balance between groups using metrics like standardized mean differences and visualization techniques like mirrored histograms. halfmoon supports both weighting and matching techniques.

Discriminant analysis and data clustering methods for high dimensional data, based on the assumption that high-dimensional data live in different subspaces with low dimensionality proposing a new parametrization of the Gaussian mixture model which combines the ideas of dimension reduction and constraints on the model.

Conducts analyses for healthcare program evaluations or intervention studies. Calculates regression analyses for standard ordinary least squares (OLS or linear) or logistic models. Performs regression models used for causal modeling such as differences-in-differences (DID) and interrupted time series (ITS) models. Provides limited interpretations of model results and a ranking of variable importance in models. Performs propensity score models, top-coding of model outcome variables, and can return new data with the newly formed variables. Conducts Bayesian analysis summaries and graphs, decision curve analysis, and produces some Shewhart control charts. Also performs Cronbach's alpha for various scale items (e.g., survey questions). See Github URL for examples in the README file. For more details on the statistical methods, see Allen & Yen (1979, ISBN:0-8185-0283-5), Angrist & Pischke (2009, ISBN:9780691120355), Cohen (1988, ISBN:0-8058-0283-5), Gebski (2012) <doi:10.1017/S0950268812000179>, Gelman & Goodrich (2019) <doi:10.1080/00031305.2018.1549100>, Gelman & Hill (2007, ISBN:978-0-521-68689-1), Harrell (2015, ISBN:978-3-319-19424-0), Imbens & Rubin (2015, ISBN:978-0-521-88588-1), Kline (1999, ISBN:9780415211581), Kruschke (2014, ISBN:9780124058880), Linden (2015) <doi:10.1177/1536867X1501500208>, Merlo (2006) <doi:10.1136/jech.2004.029454>, Muthen & Satorra (1995) <doi:10.2307/271070>, Pitman (1993, ISBN:978-0-387-97974-8), Rabe-Hesketh & Skrondal (2008, ISBN:978-1-59718-040-5), Rosenbaum (2010, ISBN:978-1-4419-1212-1), Ryan (2011, ISBN:978-0-470-59074-4), and Vickers & Elkin (2006) <doi:10.1177/0272989X06295361>.

Raster based flood modelling internally using hyd1d', an R package to interpolate 1d water level and gauging data. The package computes flood extent and duration through strategies originally developed for INFORM', an ArcGIS'-based hydro-ecological modelling framework. It does not provide a full, physical hydraulic modelling algorithm, but a simplified, near real time GIS approach for flood extent and duration modelling. Computationally demanding annual flood durations have been computed already and data products were published by Weber (2022) <doi:10.1594/PANGAEA.948042>.

This package provides a unified interface for accessing diverse web-published hydrometric data sources across Canada, presenting users with consistent tabular output regardless of the underlying data source.

Harriet was Charles Darwin's pet tortoise (possibly). harrietr implements some function to manipulate distance matrices and phylogenetic trees to make it easier to plot with ggplot2 and to manipulate using tidyverse tools.

An algorithm for time series analysis that leverages hidden Markov models, cluster analysis, and mixture distributions to segment data, detect patterns and predict future sequences.

Pure set data visualization approaches are often limited in scalability due to the combinatorial explosion of distinct set families as the number of sets under investigation increases. hierarchicalSets applies a set centric hierarchical clustering of the sets under investigation and uses this hierarchy as a basis for a range of scalable visual representations. hierarchicalSets is especially well suited for collections of sets that describe comparable comparable entities as it relies on the sets to have a meaningful relational structure.

This package provides univariate and indexed (multivariate) nonparametric smoothed kernel estimators for the future conditional hazard rate function when time-dependent covariates are present, a bandwidth selector for the estimator's implementation and pointwise and uniform confidence bands. Methods used in the package refer to Bagkavos, Isakson, Mammen, Nielsen and Proust-Lima (2025) <doi:10.1093/biomet/asaf008>.

Implementation of selected high-dimensional statistical and econometric methods for estimation and inference. Efficient estimators and uniformly valid confidence intervals for various low-dimensional causal/ structural parameters are provided which appear in high-dimensional approximately sparse models. Including functions for fitting heteroscedastic robust Lasso regressions with non-Gaussian errors and for instrumental variable (IV) and treatment effect estimation in a high-dimensional setting. Moreover, the methods enable valid post-selection inference and rely on a theoretically grounded, data-driven choice of the penalty. Chernozhukov, Hansen, Spindler (2016) <arXiv:1603.01700>.

Returns a Hasse diagram of the layout structure (Bate and Chatfield (2016)) <doi:10.1080/00224065.2016.11918173> or the restricted layout structure (Bate and Chatfield (2016)) <doi:10.1080/00224065.2016.11918174> of an experimental design.

This package provides a collection of datasets and supporting functions accompanying Health Metrics and the Spread of Infectious Diseases by Federica Gazzelloni (2024). This package provides data for health metrics calculations, including Disability-Adjusted Life Years (DALYs), Years of Life Lost (YLLs), and Years Lived with Disability (YLDs), as well as additional tools for analyzing and visualizing health data. Federica Gazzelloni (2024) <doi:10.5281/zenodo.10818338>.

An S4 class and several functions which utilize internally stored datasets and gauging data enable 1d water level interpolation. The S4 class (WaterLevelDataFrame) structures the computation and visualisation of 1d water level information along the German federal waterways Elbe and Rhine. hyd1d delivers 1d water level data - extracted from the FLYS database - and validated gauging data - extracted from the hydrological database WISKI7 - package-internally. For computations near real time gauging data are queried externally from the PEGELONLINE REST API <https://pegelonline.wsv.de/webservice/dokuRestapi>.

The harmonic mean p-value (HMP) test combines p-values and corrects for multiple testing while controlling the strong-sense family-wise error rate. It is more powerful than common alternatives including Bonferroni and Simes procedures when combining large proportions of all the p-values, at the cost of slightly lower power when combining small proportions of all the p-values. It is more stringent than controlling the false discovery rate, and possesses theoretical robustness to positive correlations between tests and unequal weights. It is a multi-level test in the sense that a superset of one or more significant tests is certain to be significant and conversely when the superset is non-significant, the constituent tests are certain to be non-significant. It is based on MAMML (model averaging by mean maximum likelihood), a frequentist analogue to Bayesian model averaging, and is theoretically grounded in generalized central limit theorem. For detailed examples type vignette("harmonicmeanp") after installation. Version 3.0 addresses errors in versions 1.0 and 2.0 that led function p.hmp to control the familywise error rate only in the weak sense, rather than the strong sense as intended.

User-friendly and fast set of functions for estimating parameters of hierarchical Bayesian species distribution models (Latimer and others 2006 <doi:10.1890/04-0609>). Such models allow interpreting the observations (occurrence and abundance of a species) as a result of several hierarchical processes including ecological processes (habitat suitability, spatial dependence and anthropogenic disturbance) and observation processes (species detectability). Hierarchical species distribution models are essential for accurately characterizing the environmental response of species, predicting their probability of occurrence, and assessing uncertainty in the model results.

Input multiple versions of a source document, and receive HTML code for a highlighted version of the source document indicating the frequency of occurrence of phrases in the different versions. This method is described in Chapter 3 of Rogers (2024) <https://digitalcommons.unl.edu/dissertations/AAI31240449/>.

Vapor pressure, relative humidity, absolute humidity, specific humidity, and mixing ratio are commonly used water vapor measures in meteorology. This R package provides functions for calculating saturation vapor pressure (hPa), partial water vapor pressure (Pa), relative humidity (%), absolute humidity (kg/m^3), specific humidity (kg/kg), and mixing ratio (kg/kg) from temperature (K) and dew point (K). Conversion functions between humidity measures are also provided.

Cellular responses to perturbations are highly heterogeneous and depend largely on the initial state of cells. Connecting post-perturbation cells via cellular trajectories to untreated cells (e.g. by leveraging metabolic labeling information) enables exploitation of intercellular heterogeneity as a combined knock-down and overexpression screen to identify pathway modulators, termed Heterogeneity-seq (see Berg et al <doi:10.1101/2024.10.28.620481>). This package contains functions to generate cellular trajectories based on scSLAM-seq (single-cell, thiol-(SH)-linked alkylation of RNA for metabolic labelling sequencing) time courses, functions to identify pathway modulators and to visualize the results.

This package performs hypergraph-based setwise variable selection with false discovery rate control (Organ, Kenney & Gu, 2026, <doi:10.48550/arXiv.2606.20514>). The idea is, in addition to selecting individual predictors when there is sufficient evidence, to also test all pairs of predictors, and when there is insufficient evidence to be sure which is the true predictor, it will select possibly overlapping pairs, for which there is strong evidence that at least one is a true predictor. The method is designed to control a generalised false discovery rate, where discoveries are counted based on the number of independent sets. The function of this package is similar to the hypergraph.sizing package, but this package is optimised for faster computation in the case where we test all pairs of predictors. The package also includes functions for counting independent sets in a graph or hypergraph, either exactly or approximately. There is also a very limited function for isotonic regression, which is designed for fast computation in the specific case needed for hypergraph variable selection, rather than for general use.

Prints a user-supplied message alongside a small ASCII-art frog in one of several moods (default, sleepy, angry, party, ninja). Designed as a quirky alternative to print for adding visual flair to console output in scripts, demos, teaching materials, and command-line tools.

This package provides a set of routines to quickly download and import the HUGO Gene Nomenclature Committee (HGNC) data set on mapping of gene symbols to gene entries in other genomic databases or resources.