Some enhancements, extensions and additions to the facilities of the recommended MASS package that are useful mainly for teaching purposes, with more convenient default settings and user interfaces. Key functions from MASS are imported and re-exported to avoid masking conflicts. In addition we provide some additional functions mainly used to illustrate coding paradigms and techniques, such as Gramm-Schmidt orthogonalisation and generalised eigenvalue problems.

Econometric analysis of multiple-input-multiple-output production technologies with ray-based input distance functions as suggested by Price and Henningsen (2023): "A Ray-Based Input Distance Function to Model Zero-Valued Output Quantities: Derivation and an Empirical Application", Journal of Productivity Analysis 60, p. 179-188, <doi:10.1007/s11123-023-00684-1>.

Calculates exact hypothesis tests to compare a treatment and a reference group with respect to multiple binary endpoints. The tested null hypothesis is an identical multidimensional distribution of successes and failures in both groups. The alternative hypothesis is a larger success proportion in the treatment group in at least one endpoint. The tests are based on the multivariate permutation distribution of subjects between the two groups. For this permutation distribution, rejection regions are calculated that satisfy one of different possible optimization criteria. In particular, regions with maximal exhaustion of the nominal significance level, maximal power under a specified alternative or maximal number of elements can be found. Optimization is achieved by a branch-and-bound algorithm. By application of the closed testing principle, the global hypothesis tests are extended to multiple testing procedures.

This package provides a framework for multipurpose optimal resource allocation in survey sampling, extending the classical optimal allocation principles introduced by Tschuprow (1923) and Neyman (1934) to multidomain and multivariate allocation problems. The primary method mosalloc() allows for the consideration of precision and cost constraints at the subpopulation level while minimizing either a vector of sampling errors or survey costs across a broad range of optimal sample allocation problems. The approach supports both single- and multistage designs. For single-stage stratified random sampling, the mosallocSTRS() function offers a user- friendly interface. Sensitivity analysis is supported through the problem's dual variables, which are naturally obtained via the internal use of the Embedded Conic Solver from the ECOSolveR package. See Willems (2025, <doi:10.25353/ubtr-9200-484c-5c89>) for a detailed description of the theory behind MOSAlloc'.

This package provides functions for dimension reduction, using MAVE (Minimum Average Variance Estimation), OPG (Outer Product of Gradient) and KSIR (sliced inverse regression of kernel version). Methods for selecting the best dimension are also included. Xia (2002) <doi:10.1111/1467-9868.03411>; Xia (2007) <doi:10.1214/009053607000000352>; Wang (2008) <doi:10.1198/016214508000000418>.

Fast manipulation of symbolic multivariate polynomials using the Map class of the Standard Template Library. The package uses print and coercion methods from the mpoly package but offers speed improvements. It is comparable in speed to the spray package for sparse arrays, but retains the symbolic benefits of mpoly'. To cite the package in publications, use Hankin 2022 <doi:10.48550/ARXIV.2210.15991>. Uses disordR discipline.

This package provides a modeltime extension that implements time series ensemble forecasting methods including model averaging, weighted averaging, and stacking. These techniques are popular methods to improve forecast accuracy and stability.

Framework for the Item Response Theory analysis of dichotomous and ordinal polytomous outcomes under the assumption of within-item multidimensionality and discreteness of the latent traits. The fitting algorithms allow for missing responses and for different item parametrizations and are based on the Expectation-Maximization paradigm. Individual covariates affecting the class weights may be included in the new version together with possibility of constraints on all model parameters.

This package provides methods for color labeling, calculation of eigengenes, merging of closely related modules.

Density, distribution function, quantile function, and random generation function based on Salem, H. M. (2019)<doi:10.5539/mas.v13n2p54>. In addition, a numerical method for maximum likelihood estimation is provided.

Multivariable Fractional Polynomial algorithm for model-building. Fractional polynomials are used to represent curvature in regression models. A key reference is Royston and Altman, 1994.

This package contains basic tools for performing multiple-output quantile regression and computing regression quantile contours by means of directional regression quantiles. In the location case, one can thus obtain halfspace depth contours in two to six dimensions. Hallin, M., Paindaveine, D. and Å iman, M. (2010) Multivariate quantiles and multiple-output regression quantiles: from L1 optimization to halfspace depth. Annals of Statistics 38, 635-669 For more references about the method, see Help pages.

It provides functions to compute the values of different modifications of the Rand and Wallace indices. The indices are used to measure the stability or similarity of two partitions obtained on two different sets of units with a non-empty intercept. Splitting and merging of clusters can (depends on the selected index) have a different effect on the value of the indices. The indices are proposed in Cugmas and Ferligoj (2018) <http://ibmi.mf.uni-lj.si/mz/2018/no-1/Cugmas2018.pdf>.

Several classes for moment-based models are defined. The classes are defined for moment conditions derived from a single equation or a system of equations. The conditions can also be expressed as functions or formulas. Several methods are also offered to facilitate the development of different estimation techniques. The methods that are currently provided are the Generalized method of moments (Hansen 1982; <doi:10.2307/1912775>), for single equations and systems of equation, and the Generalized Empirical Likelihood (Smith 1997; <doi:10.1111/j.0013-0133.1997.174.x>, Kitamura 1997; <doi:10.1214/aos/1069362388>, Newey and Smith 2004; <doi:10.1111/j.1468-0262.2004.00482.x>, and Anatolyev 2005 <doi:10.1111/j.1468-0262.2005.00601.x>). Some work is being done to add tools to deal with weak and/or many instruments. This includes K-Class estimators (Limited Information Maximum Likelihood and Fuller), Anderson and Rubin statistic test, etc.

An open-source implementation of latent variable methods and multivariate modeling tools. The focus is on exploratory analyses using dimensionality reduction methods including low dimensional embedding, classical multivariate statistical tools, and tools for enhanced interpretation of machine learning methods (i.e. intelligible models to provide important information for end-users). Target domains include extension to dedicated applications e.g. for manufacturing process modeling, spectroscopic analyses, and data mining.

Describes spatial patterns of categorical raster data for any defined regular and irregular areas. Patterns are described quantitatively using built-in signatures based on co-occurrence matrices but also allows for any user-defined functions. It enables spatial analysis such as search, change detection, and clustering to be performed on spatial patterns (Nowosad (2021) <doi:10.1007/s10980-020-01135-0>).

This package contains the function mice.impute.midastouch(). Technically this function is to be run from within the mice package (van Buuren et al. 2011), type ??mice. It substitutes the method pmm within mice by midastouch'. The authors have shown that midastouch is superior to default pmm'. Many ideas are based on Siddique / Belin 2008's MIDAS.

Implementation of two tools to merge Hardware Event Monitors (HEMs) from different subexperiments. Hardware Reading and Merging (HRM), which uses order statistics to merge; and MUlti-Correlation HEM (MUCH) which merges using a multivariate normal distribution. The reference paper for HRM is: S. Vilardell, I. Serra, R. Santalla, E. Mezzetti, J. Abella and F. J. Cazorla, "HRM: Merging Hardware Event Monitors for Improved Timing Analysis of Complex MPSoCs," in IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, vol. 39, no. 11, pp. 3662-3673, Nov. 2020, <doi:10.1109/TCAD.2020.3013051>. For MUCH: S. Vilardell, I. Serra, E. Mezzetti, J. Abella, and F. J. Cazorla. 2021. "MUCH: exploiting pairwise hardware event monitor correlations for improved timing analysis of complex MPSoCs". In Proceedings of the 36th Annual ACM Symposium on Applied Computing (SAC 21). Association for Computing Machinery. <doi:10.1145/3412841.3441931>. This work has been supported by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement No. 772773).

This package provides a framework for analyzing broth microdilution assays in various 96-well plate designs, visualizing results and providing descriptive and (simple) inferential statistics (i.e. summary statistics and sign test). The functions are designed to add metadata to 8 x 12 tables of absorption values, creating a tidy data frame. Users can choose between clean-up procedures via function parameters (which covers most cases) or user prompts (in cases with complex experimental designs). Users can also choose between two validation methods, i.e. exclusion of absorbance values above a certain threshold or manual exclusion of samples. A function for visual inspection of samples with their absorption values over time for certain group combinations helps with the decision. In addition, the package includes functions to subtract the background absorption (usually at time T0) and to calculate the growth performance compared to a baseline. Samples can be visually inspected with their absorption values displayed across time points for specific group combinations. Core functions of this package (i.e. background subtraction, sample validation and statistics) were inspired by the manual calculations that were applied in Tewes and Muller (2020) <doi:10.1038/s41598-020-67600-7>.

This package provides methods to analyze micro-randomized trials (MRTs) with binary treatment options. Supports four types of analyses: (1) proximal causal excursion effects, including weighted and centered least squares (WCLS) for continuous proximal outcomes by Boruvka et al. (2018) <doi:10.1080/01621459.2017.1305274> and the estimator for marginal excursion effect (EMEE) for binary proximal outcomes by Qian et al. (2021) <doi:10.1093/biomet/asaa070>; (2) distal causal excursion effects (DCEE) for continuous distal outcomes using a two-stage estimator by Qian (2025) <doi:10.1093/biomtc/ujaf134>; (3) mediated causal excursion effects (MCEE) for continuous distal outcomes, estimating natural direct and indirect excursion effects in the presence of time-varying mediators by Qian (2025) <doi:10.48550/arXiv.2506.20027>; and (4) standardized proximal effect size estimation for continuous proximal outcomes, generalizing the approach in Luers et al. (2019) <doi:10.1007/s11121-017-0862-5> to allow adjustment for baseline and time-varying covariates for improved efficiency.

Generates DiagrammeR model diagrams for hierarchical linear mixed effects models. Details can be found in Linse (2026) <doi:10.6339/26-JDS1222>.

The Mutual Information Index (M) introduced to social science literature by Theil and Finizza (1971) <doi:10.1080/0022250X.1971.9989795> is a multigroup segregation measure that is highly decomposable and that according to Frankel and Volij (2011) <doi:10.1016/j.jet.2010.10.008> and Mora and Ruiz-Castillo (2011) <doi:10.1111/j.1467-9531.2011.01237.x> satisfies the Strong Unit Decomposability and Strong Group Decomposability properties. This package allows computing and decomposing the total index value into its "between" and "within" terms. These last terms can also be decomposed into their contributions, either by group or unit characteristics. The factors that produce each "within" term can also be displayed at the user's request. The results can be computed considering a variable or sets of variables that define separate clusters.

Implementation of commonly used p-value-based and parametric multiple testing procedures (computation of adjusted p-values and simultaneous confidence intervals) and parallel gatekeeping procedures based on the methodology presented in the book "Multiple Testing Problems in Pharmaceutical Statistics" (edited by Alex Dmitrienko, Ajit C. Tamhane and Frank Bretz) published by Chapman and Hall/CRC Press 2009.

The mycobacrvR package contains utilities to provide detailed information for B cell and T cell epitopes for predicted adhesins from various servers such as ABCpred, Bcepred, Bimas, Propred, NetMHC and IEDB. Please refer the URL below to download data files (data_mycobacrvR.zip) used in functions of this package.