This package provides a broad collection of datasets focused on health, biomechanics, and human motion. It includes clinical, physiological, and kinematic information from diverse sources, covering aspects such as surgery outcomes, vital signs, rheumatoid arthritis, osteoarthritis, accelerometry, gait analysis, motion sensing, and biomechanics experiments. Designed for researchers, analysts, and students, the package facilitates exploration and analysis of data related to health monitoring, physical activity, and rehabilitation.

The Hybrid design is a combination of model-assisted design (e.g., the modified Toxicity Probability Interval design) with dose-toxicity model-based design for phase I dose-finding studies. The hybrid design controls the overdosing toxicity well and leads to a recommended dose closer to the true maximum tolerated dose (MTD) due to its ability to calibrate for an intermediate dose. More details can be found in Liao et al. 2022 <doi:10.1002/ijc.34203>.

This package provides access to datasets published by Hlà daÄ státu <https://www.hlidacstatu.cz/>, a Czech watchdog, via their API.

This package provides functions and methods for organizing data in hypercubes (i.e., a multi-dimensional cube). Cubes are generated from molten data frames. Each cube can be manipulated with five operations: rotation (change.dimensionOrder()), dicing and slicing (add.selection(), remove.selection()), drilling down (add.aggregation()), and rolling up (remove.aggregation()).

Detection of haplotype patterns that include single nucleotide polymorphisms (SNPs) and non-contiguous haplotypes that are associated with a phenotype. Methods for implementing HTRX are described in Yang Y, Lawson DJ (2023) <doi:10.1093/bioadv/vbad038> and Barrie W, Yang Y, Irving-Pease E.K, et al (2024) <doi:10.1038/s41586-023-06618-z>.

This package provides a suite of routines for the hyperdirichlet distribution and reified Bradley-Terry; supersedes the hyperdirichlet package; uses disordR discipline <doi:10.48550/ARXIV.2210.03856>. To cite in publications please use Hankin 2017 <doi:10.32614/rj-2017-061>, and for Generalized Plackett-Luce likelihoods use Hankin 2024 <doi:10.18637/jss.v109.i08>.

This package provides methods for analysing and forecasting hierarchical and grouped time series. The available forecast methods include bottom-up, top-down, optimal combination reconciliation (Hyndman et al. 2011) <doi:10.1016/j.csda.2011.03.006>, and trace minimization reconciliation (Wickramasuriya et al. 2018) <doi:10.1080/01621459.2018.1448825>.

Hierarchical Modelling of Species Communities (HMSC) is a model-based approach for analyzing community ecological data. This package implements it in the Bayesian framework with Gibbs Markov chain Monte Carlo (MCMC) sampling (Tikhonov et al. (2020) <doi:10.1111/2041-210X.13345>).

Identification of recombination events, haplotype reconstruction, sire imputation and pedigree reconstruction using half-sib family SNP data.

Simple tools for converting columns to new data types. Intuitive functions for columns with missing values.

This package provides a protocol that facilitates the processing and analysis of Hydrogen-Deuterium Exchange Mass Spectrometry data using p-value statistics and Critical Interval analysis. It provides a pipeline for analyzing data from HDXExaminer (Sierra Analytics, Trajan Scientific), automating matching and comparison of protein states through Welch's T-test and the Critical Interval statistical framework. Additionally, it simplifies data export, generates PyMol scripts, and ensures calculations meet publication standards. HDXBoxeR assists in various aspects of hydrogen-deuterium exchange data analysis, including reprocessing data, calculating parameters, identifying significant peptides, generating plots, and facilitating comparison between protein states. For details check papers by Hageman and Weis (2019) <doi:10.1021/acs.analchem.9b01325> and Masson et al. (2019) <doi:10.1038/s41592-019-0459-y>. HDXBoxeR citation: Janowska et al. (2024) <doi:10.1093/bioinformatics/btae479>.

This package provides functions to access data from the US Department of Housing and Urban Development <https://www.huduser.gov/portal/dataset/fmr-api.html>.

Raster based flood modelling internally using hyd1d', an R package to interpolate 1d water level and gauging data. The package computes flood extent and duration through strategies originally developed for INFORM', an ArcGIS'-based hydro-ecological modelling framework. It does not provide a full, physical hydraulic modelling algorithm, but a simplified, near real time GIS approach for flood extent and duration modelling. Computationally demanding annual flood durations have been computed already and data products were published by Weber (2022) <doi:10.1594/PANGAEA.948042>.

Efficient implementation of penalized regression with hierarchical nested parametrization for grouped data. The package provides penalized regression methods that decompose subgroup specific effects into shared global effects, Major subgroup specific effects, and Minor subgroup specific effects, enabling structured borrowing of information across related clinical subgroups. Both lasso and hierarchical overlapping group lasso penalties are supported to encourage sparsity while respecting the nested subgroup structure. Efficient computation is achieved through a modified design matrix representation and a custom algorithm for overlapping group penalties.

The HMS (Hierarchic Memetic Strategy) is a composite global optimization strategy consisting of a multi-population evolutionary strategy and some auxiliary methods. The HMS makes use of a dynamically-evolving data structure that provides an organization among the component populations. It is a tree with a fixed maximal height and variable internal node degree. Each component population is governed by a particular evolutionary engine. This package provides a simple R implementation with examples of using different genetic algorithms as the population engines. References: J. Sawicki, M. Å oÅ , M. SmoÅ ka, J. Alvarez-Aramberri (2022) <doi:10.1007/s11047-020-09836-w>.

Apply an adaptation of the SuperFastHash algorithm to any R object. Hash whole R objects or, for vectors or lists, hash R objects to obtain a set of hash values that is stored in a structure equivalent to the input. See <http://www.azillionmonkeys.com/qed/hash.html> for a description of the hash algorithm.

This package provides a toolkit for the analysis and management of data for genes in the so-called "Human Leukocyte Antigen" (HLA) region. Functions extract reference data from the Anthony Nolan HLA Informatics Group/ImmunoGeneTics HLA GitHub repository (ANHIG/IMGTHLA) <https://github.com/ANHIG/IMGTHLA>, validate Genotype List (GL) Strings, convert between UNIFORMAT and GL String Code (GLSC) formats, translate HLA alleles and GLSCs across ImmunoPolymorphism Database (IPD) IMGT/HLA Database release versions, identify differences between pairs of alleles at a locus, generate customized, multi-position sequence alignments, trim and convert allele-names across nomenclature epochs, and extend existing data-analysis methods. Tran et al., (2025) <doi:10.1111/iji.70013>.

Fast, model-agnostic implementation of different H-statistics introduced by Jerome H. Friedman and Bogdan E. Popescu (2008) <doi:10.1214/07-AOAS148>. These statistics quantify interaction strength per feature, feature pair, and feature triple. The package supports multi-output predictions and can account for case weights. In addition, several variants of the original statistics are provided. The shape of the interactions can be explored through partial dependence plots or individual conditional expectation plots. DALEX explainers, meta learners ('mlr3', tidymodels', caret') and most other models work out-of-the-box.

Fitting hidden Markov models using automatic differentiation and Laplace approximation, allowing for fast inference and flexible covariate effects (including random effects and smoothing splines) on model parameters. The package is described by Michelot (2025) <doi:10.18637/jss.v114.i05>.

Test the significance of coefficients in high dimensional generalized linear models.

An implementation of the modelling and reporting features described in reference textbook and guidelines (Briggs, Andrew, et al. Decision Modelling for Health Economic Evaluation. Oxford Univ. Press, 2011; Siebert, U. et al. State-Transition Modeling. Medical Decision Making 32, 690-700 (2012).): deterministic and probabilistic sensitivity analysis, heterogeneity analysis, time dependency on state-time and model-time (semi-Markov and non-homogeneous Markov models), etc.

Calculates heat-stress indices from meteorological observations, including the physically based wet-bulb globe temperature model described by Liljegren et al. (2008) <doi:10.1080/15459620802310770>. The package provides an independently maintained R implementation with row-level diagnostics, configurable physical controls, and batch processing for the Liljegren method; it is not a bitwise-compatible port of the original program, and cross-implementation differences are expected.

This package provides functions for combining model outputs (e.g. predictions or estimates) from multiple models into an aggregated ensemble model output.

Estimates the parameters of infiltration and water retention models using the curve-fitting methods as shown in Omuto and Gumbe (2009) <doi:10.1016/j.cageo.2008.08.011>. The models considered are those that are commonly used in soil science. Version 2 of the package has new models for water retention characteristic curves.