This package provides a suite of tools for literature-based discovery in biomedical research. Provides functions for retrieving scientific articles from PubMed and other NCBI databases, extracting biomedical entities (diseases, drugs, genes, etc.), building co-occurrence networks, and applying various discovery models including ABC', AnC', LSI', and BITOLA'. The package also includes visualization tools for exploring discovered connections.

Simulate expected equilibrium length composition, yield-per-recruit, and the spawning potential ratio (SPR) using the length-based SPR (LBSPR) model. Fit the LBSPR model to length data to estimate selectivity, relative apical fishing mortality, and the spawning potential ratio for data-limited fisheries. See Hordyk et al (2016) <doi:10.1139/cjfas-2015-0422> for more information about the LBSPR assessment method.

Functionalities for calculating the local score and calculating statistical relevance (p-value) to find a local Score in a sequence of given distribution (D. Robelin, S. Déjean, S. Mercier (2025) <doi:10.24072/pcjournal.650> ; S. Mercier and J.-J. Daudin (2001) <https://hal.science/hal-00714174/>) ; S. Karlin and S. Altschul (1990) <https://pmc.ncbi.nlm.nih.gov/articles/PMC53667/> ; S. Mercier, D. Cellier and F. Charlot (2003) <https://hal.science/hal-00937529v1/> ; A. Lagnoux, S. Mercier and P. Valois (2017) <doi:10.1093/bioinformatics/btw699> ).

This package provides tools for model specification in the latent variable framework (add-on to the lava package). The package contains three main functionalities: Wald tests/F-tests with improved control of the type 1 error in small samples, adjustment for multiple comparisons when searching for local dependencies, and adjustment for multiple comparisons when doing inference for multiple latent variable models.

This package provides a framework to load text and excel files through a shiny graphical interface. It allows renaming, transforming, ordering and removing variables. It includes basic exploratory methods such as the mean, median, mode, normality test, histogram and correlation.

Parse various reflectance/transmittance/absorbance spectra file formats to extract spectral data and metadata, as described in Gruson, White & Maia (2019) <doi:10.21105/joss.01857>. Among other formats, it can import files from Avantes <https://www.avantes.com/>, CRAIC <https://www.microspectra.com/>, and OceanOptics'/'OceanInsight <https://www.oceanoptics.com/> brands.

An implementation of the Input-Output model developed by Wassily Leontief that represents the interdependencies between different sectors of a national economy or different regional economies.

Temporary and permanent message queues for R. Built on top of SQLite databases. SQLite provides locking, and makes it possible to detect crashed consumers. Crashed jobs can be automatically marked as "failed", or put in the queue again, potentially a limited number of times.

Print vectors (and data frames) of floating point numbers using a non-scientific format optimized for human readers. Vectors of numbers are rounded using significant digits, aligned at the decimal point, and all zeros trailing the decimal point are dropped. See: Wright (2016). Lucid: An R Package for Pretty-Printing Floating Point Numbers. In JSM Proceedings, Statistical Computing Section. Alexandria, VA: American Statistical Association. 2270-2279.

This package implements a Gibbs sampler to do linear regression with multiple covariates, multiple responses, Gaussian measurement errors on covariates and responses, Gaussian intrinsic scatter, and a covariate prior distribution which is given by either a Gaussian mixture of specified size or a Dirichlet process with a Gaussian base distribution. Described further in Mantz (2016) <DOI:10.1093/mnras/stv3008>.

Select statistically similar research groups by backward selection using various robust algorithms, including a heuristic based on linear discriminant analysis, multiple heuristics based on the test statistic, and parallelized exhaustive search.

In Latent Space Item Response Models, subjects and items are embedded in a multidimensional Euclidean latent space. As such, interactions among persons, items, and person-item combinations can be revealed that are unmodelled in more conventional item response theory models. This package implements the methods from Molenaar & Jeon (in press) and can be used to fit Latent Space Item Response Models to data using joint maximum likelihood estimation. The package can handle binary data, ordinal data, and data with mixed scales. The package incorporates facilities for data simulation, rotation of the latent space, and K-fold cross-validation to select the number of dimensions of the latent space.

Lazy read for drawings. A dplyr back end for data sources supported by GDAL vector drivers, that allows working with local or remote sources as if they are in-memory data frames. Basic features works with any drawing format ('GDAL vector data source') supported by the sf package.

An (upper) level set of a function is the set of inputs for which the function value is at or above a specified threshold. (Also called an excursion set). Applications of level sets include confidence or credible regions for parameters of statistical models, where the function is the likelihood or posterior density; regions where classification rules assign high probability to a given class; and scientific or engineering models where one is interested in input regions for which model output is above a threshold. This package maps out the boundary of a level set by finding its intersections with collections of 1-dimensional rays, generalizing a proposal by Kim and Lindsay (Statistica Sinica 21:923-948, 2011). Tools are provided to generate rays, find intersections, and visualize results. The package makes few assumptions about the studied function: it may be discontinuous, it may have a complicated feasible region, and the target level set may be non-convex or have multiple, disconnected parts. Vignettes describe package usage and show examples with two to five input space dimensions.

Generates quotes from Lero Lero', a database for meaningless sentences filled with corporate buzzwords, intended to be used as corporate lorem ipsum (see <http://www.lerolero.com/> for more information). Unfortunately, quotes are currently portuguese-only.

Estimate, fit and compare Structural Equation Models (SEM) and network models (Gaussian Graphical Models; GGM) using OpenMx. Allows for two possible generalizations to include GGMs in SEM: GGMs can be used between latent variables (latent network modeling; LNM) or between residuals (residual network modeling; RNM). For details, see Epskamp, Rhemtulla and Borsboom (2017) <doi:10.1007/s11336-017-9557-x>.

This package provides a collection of tools intended to make introductory statistics easier to teach, including wrappers for common hypothesis tests and basic data manipulation. It accompanies Navarro, D. J. (2015). Learning Statistics with R: A Tutorial for Psychology Students and Other Beginners, Version 0.6.

Time-dependent Receiver Operating Characteristic curves, Area Under the Curve, and Net Reclassification Indexes for repeated measures. It is based on methods in Barbati and Farcomeni (2017) <doi:10.1007/s10260-017-0410-2>.

The Programme for International Student Assessment (PISA) is a global study conducted by the Organization for Economic Cooperation and Development (OECD) in member and non-member countries to assess educational systems by assessing 15-year-old school students academic performance in mathematics, science, and reading. This datasets contains information on their scores and other socioeconomic characteristics, information about their school and its infrastructure, as well as the countries that are taking part in the program.

Use of this package is deprecated. It has been renamed to LifeInsureR'.

This package provides a stochastic, spatially-explicit, demo-genetic model simulating the spread and evolution of a plant pathogen in a heterogeneous landscape to assess resistance deployment strategies. It is based on a spatial geometry for describing the landscape and allocation of different cultivars, a dispersal kernel for the dissemination of the pathogen, and a SEIR ('Susceptible-Exposed-Infectious-Removedâ ) structure with a discrete time step. It provides a useful tool to assess the performance of a wide range of deployment options with respect to their epidemiological, evolutionary and economic outcomes. Loup Rimbaud, Julien Papaïx, Jean-François Rey, Luke G Barrett, Peter H Thrall (2018) <doi:10.1371/journal.pcbi.1006067>.

Implementation of several phenotype-based family genetic risk scores with unified input data and data preparation functions to help facilitate the required data preparation and management. The implemented family genetic risk scores are the extended liability threshold model conditional on family history from Pedersen (2022) <doi:10.1016/j.ajhg.2022.01.009> and Pedersen (2023) <https://www.nature.com/articles/s41467-023-41210-z>, Pearson-Aitken Family Genetic Risk Scores from Krebs (2024) <doi:10.1016/j.ajhg.2024.09.009>, and family genetic risk score from Kendler (2021) <doi:10.1001/jamapsychiatry.2021.0336>.

This package provides a bioinformatics pipeline for performing taxonomic assignment of DNA metabarcoding sequence data while considering geographic location. A detailed tutorial is available at <https://urodelan.github.io/LocaTT_Tutorial/>. A manuscript describing these methods is in preparation.

The LIC criterion is to determine the most informative subsets so that the subset can retain most of the information contained in the complete data. The philosophy of the package is described in Guo G. (2022) <doi:10.1080/02664763.2022.2053949>.