This package provides tools for data analysis with multivariate Bayesian structural time series (MBSTS) models. Specifically, the package provides facilities for implementing general structural time series models, flexibly adding on different time series components (trend, season, cycle, and regression), simulating them, fitting them to multivariate correlated time series data, conducting feature selection on the regression component.

This package provides a lightweight, dependency-free data engine for R that provides a grammar for tabular and time-series manipulation. Built entirely on Base R, m61r offers a fluent, chainable API inspired by modern data tools while prioritizing memory efficiency and speed. It includes optimized versions of common data verbs such as filtering, mutation, grouped aggregation, and approximate temporal joins, making it an ideal choice for environments where external dependencies are restricted or where performance in pure R is required.

This package provides a set of functions, classes and methods for performing ABC and ABC/XYZ analyses, identifying overperforming, underperforming and constantly performing items, and plotting, analyzing as well as predicting the temporal development of items.

An R interface for the Java Machine Learning for Language Toolkit (mallet) <http://mallet.cs.umass.edu/> to estimate probabilistic topic models, such as Latent Dirichlet Allocation. We can use the R package to read textual data into mallet from R objects, run the Java implementation of mallet directly in R, and extract results as R objects. The Mallet toolkit has many functions, this wrapper focuses on the topic modeling sub-package written by David Mimno. The package uses the rJava package to connect to a JVM.

Computing the Mann-Whitney effect based on copula models. Estimation of the association parameter in survival copula models. A description of the underlying methods is described in Nakazono et al. (2024) <doi:10.3390/math12101453> and Nakazono et al. (accepted for publication in Statistical Papers).

This package provides a graphical user interface to apply an advanced method optimization algorithm to various sampling and analysis instruments. This includes generating experimental designs, uploading and viewing data, and performing various analyses to determine the optimal method. Details of the techniques used in this package are published in Gamble, Granger, & Mannion (2024) <doi:10.1021/acs.analchem.3c05763>.

Network meta-analysis and network meta-regression models for aggregate data, individual patient data, and mixtures of both individual and aggregate data using multilevel network meta-regression as described by Phillippo et al. (2020) <doi:10.1111/rssa.12579>. Models are estimated in a Bayesian framework using Stan'.

Identify and rank CpG DNA methylation conservation along the human genome. Specifically it includes bootstrapping methods to provide ranking which should adjust for the differences in length as without it short regions tend to get higher conservation scores.

Cancer cells accumulate DNA mutations as result of DNA damage and DNA repair processes. This computational framework is aimed at deciphering DNA mutational signatures operating in cancer. The framework includes modules that support raw data import and processing, mutational signature extraction, and results interpretation and visualization. The framework accepts widely used file formats storing information about DNA variants, such as Variant Call Format files. The framework performs Non-Negative Matrix Factorization to extract mutational signatures explaining the observed set of DNA mutations. Bootstrapping is performed as part of the analysis. The framework supports parallelization and is optimized for use on multi-core systems. The software was described by Fantini D et al (2020) <doi:10.1038/s41598-020-75062-0> and is based on a custom R-based implementation of the original MATLAB WTSI framework by Alexandrov LB et al (2013) <doi:10.1016/j.celrep.2012.12.008>.

This package provides modules as an organizational unit for source code. Modules enforce to be more rigorous when defining dependencies and have a local search path. They can be used as a sub unit within packages or in scripts.

Implement meta-analyses for simultaneously estimating individual means with shrinkage, isotonic regression and pretests. Include our original implementation of the isotonic regression via the pool-adjacent-violators algorithm (PAVA) algorithm. For the pretest estimator, the confidence interval for individual means are provided. Methodologies were published in Taketomi et al. (2021) <doi:10.3390/axioms10040267>, Taketomi et al. (2022) <doi:10.3390/a15010026>, Taketomi et al. (2023-) (under review).

Compute and select tuning parameters for the MRCE estimator proposed by Rothman, Levina, and Zhu (2010) <doi:10.1198/jcgs.2010.09188>. This estimator fits the multiple output linear regression model with a sparse estimator of the error precision matrix and a sparse estimator of the regression coefficient matrix.

This package provides a collection of functions for computations and visualizations of microbial pan-genomes.

Maximum likelihood Gaussian process modeling for univariate and multi-dimensional outputs with diagnostic plots following Santner et al (2003) <doi:10.1007/978-1-4757-3799-8>. Contact the maintainer for a package version that includes sensitivity analysis.

This package provides a complete toolkit to process the Munich ChronoType Questionnaire (MCTQ) for its three versions (standard, micro, and shift). MCTQ is a quantitative and validated tool to assess chronotypes using peoples sleep behavior, originally presented by Till Roenneberg, Anna Wirz-Justice, and Martha Merrow (2003, <doi:10.1177/0748730402239679>).

Calculates two sets of post-hoc variable importance measures for multivariate random forests. The first set of variable importance measures are given by the sum of mean split improvements for splits defined by feature j measured on user-defined examples (i.e., training or testing samples). The second set of importance measures are calculated on a per-outcome variable basis as the sum of mean absolute difference of node values for each split defined by feature j measured on user-defined examples (i.e., training or testing samples). The user can optionally threshold both sets of importance measures to include only splits that are statistically significant as measured using an F-test.

This package provides a set of tools for fitting Markov-modulated linear regression, where responses Y(t) are time-additive, and model operates in the external environment, which is described as a continuous time Markov chain with finite state space. Model is proposed by Alexander Andronov (2012) <arXiv:1901.09600v1> and algorithm of parameters estimation is based on eigenvalues and eigenvectors decomposition. Markov-switching regression models have the same idea of varying the regression parameters randomly in accordance with external environment. The difference is that for Markov-modulated linear regression model the external environment is described as a continuous-time homogeneous irreducible Markov chain with known parameters while switching models consider Markov chain as unobserved and estimation procedure involves estimation of transition matrix. These models have significant differences in terms of the analytical approach. Also, package provides a set of data simulation tools for Markov-modulated linear regression (for academical/research purposes). Research project No. 1.1.1.2/VIAA/1/16/075.

This package provides a compilation of more than 80 functions designed to quantitatively and visually evaluate prediction performance of regression (continuous variables) and classification (categorical variables) of point-forecast models (e.g. APSIM, DSSAT, DNDC, supervised Machine Learning). For regression, it includes functions to generate plots (scatter, tiles, density, & Bland-Altman plot), and to estimate error metrics (e.g. MBE, MAE, RMSE), error decomposition (e.g. lack of accuracy-precision), model efficiency (e.g. NSE, E1, KGE), indices of agreement (e.g. d, RAC), goodness of fit (e.g. r, R2), adjusted correlation coefficients (e.g. CCC, dcorr), symmetric regression coefficients (intercept, slope), and mean absolute scaled error (MASE) for time series predictions. For classification (binomial and multinomial), it offers functions to generate and plot confusion matrices, and to estimate performance metrics such as accuracy, precision, recall, specificity, F-score, Cohen's Kappa, G-mean, and many more. For more details visit the vignettes <https://adriancorrendo.github.io/metrica/>.

Generalized Additive Model for Location, Scale and Shape (GAMLSS) with zero inflated beta (BEZI) family for analysis of microbiome relative abundance data (with various options for data transformation/normalization to address compositional effects) and random effects meta-analysis models for meta-analysis pooling estimates across microbiome studies are implemented. Random Forest model to predict microbiome age based on relative abundances of shared bacterial genera with the Bangladesh data (Subramanian et al 2014), comparison of multiple diversity indexes using linear/linear mixed effect models and some data display/visualization are also implemented. The reference paper is published by Ho NT, Li F, Wang S, Kuhn L (2019) <doi:10.1186/s12859-019-2744-2> .

The monotone package contains a fast up-and-down-blocks implementation for the pool-adjacent-violators algorithm for simple linear ordered monotone regression, including two spin-off functions for unimodal and bivariate monotone regression (see <doi:10.18637/jss.v102.c01>).

This package provides a leadership-inference framework for multivariate time series. The framework for multiple-faction-leadership inference from coordinated activities or mFLICA uses a notion of a leader as an individual who initiates collective patterns that everyone in a group follows. Given a set of time series of individual activities, our goal is to identify periods of coordinated activity, find factions of coordination if more than one exist, as well as identify leaders of each faction. For each time step, the framework infers following relations between individual time series, then identifying a leader of each faction whom many individuals follow but it follows no one. A faction is defined as a group of individuals that everyone follows the same leader. mFLICA reports following relations, leaders of factions, and members of each faction for each time step. Please see Chainarong Amornbunchornvej and Tanya Berger-Wolf (2018) <doi:10.1137/1.9781611975321.62> for methodology and Chainarong Amornbunchornvej (2021) <doi:10.1016/j.softx.2021.100781> for software when referring to this package in publications.

Automatically estimate 11 effect size measures from a well-formatted dataset. Various other functions can help, for example, removing dependency between several effect sizes, or identifying differences between two datasets. This package is mainly designed to assist in conducting a systematic review with a meta-analysis but can be useful to any researcher interested in estimating an effect size.

This package provides a suite of tools for transforming an existing workflow into a self-documenting pipeline with very minimal upfront costs. Segments of the pipeline are specified in much the same way a Make rule is, by declaring an executable recipe (which might be an R script), along with the corresponding targets and dependencies. When the entire pipeline is run through, only those recipes that need to be executed will be. Meanwhile, execution metadata is captured behind the scenes for later inspection.

Describes spatial patterns of categorical raster data for any defined regular and irregular areas. Patterns are described quantitatively using built-in signatures based on co-occurrence matrices but also allows for any user-defined functions. It enables spatial analysis such as search, change detection, and clustering to be performed on spatial patterns (Nowosad (2021) <doi:10.1007/s10980-020-01135-0>).