r-anota2seq 1.34.0
Propagated dependencies: r-deseq2@1.52.0 r-edger@4.10.0 r-limma@3.68.3 r-multtest@2.68.0 r-qvalue@2.44.0 r-rcolorbrewer@1.1-3 r-summarizedexperiment@1.42.0
Channel: guix
Home page: https://bioconductor.org/packages/anota2seq
Licenses: GPL 3
Build system: r
Synopsis: Transcriptome-wide analysis of translational efficiency
Description:
The anota2seq package provides analysis of translational efficiency and differential expression analysis for polysome-profiling and ribosome-profiling studies (two or more sample classes) quantified by RNA sequencing or DNA-microarray. Polysome-profiling and ribosome-profiling typically generate data for two RNA sources, translated mRNA and total mRNA. Analysis of differential expression is used to estimate changes within each RNA source. Analysis of translational efficiency aims to identify changes in translation efficiency leading to altered protein levels that are independent of total mRNA levels or buffering, a mechanism regulating translational efficiency so that protein levels remain constant despite fluctuating total mRNA levels.
Total packages: 1