_            _    _        _         _
      /\ \         /\ \ /\ \     /\_\      / /\
      \_\ \       /  \ \\ \ \   / / /     / /  \
      /\__ \     / /\ \ \\ \ \_/ / /     / / /\ \__
     / /_ \ \   / / /\ \ \\ \___/ /     / / /\ \___\
    / / /\ \ \ / / /  \ \_\\ \ \_/      \ \ \ \/___/
   / / /  \/_// / /   / / / \ \ \        \ \ \
  / / /      / / /   / / /   \ \ \   _    \ \ \
 / / /      / / /___/ / /     \ \ \ /_/\__/ / /
/_/ /      / / /____\/ /       \ \_\\ \/___/ /
\_\/       \/_________/         \/_/ \_____\/
r-boinet 1.5.0
Propagated dependencies: r-tibble@3.3.0 r-shinydashboard@0.7.3 r-shinybs@0.61.1 r-shiny@1.11.1 r-rhandsontable@0.3.8 r-plotly@4.11.0 r-mfp@1.5.5.1 r-iso@0.0-21 r-gt@1.3.0 r-ggplot2@4.0.1 r-dt@0.34.0 r-copula@1.1-7
Channel: guix-cran
Location: guix-cran/packages/b.scm (guix-cran packages b)
Home page: https://cran.r-project.org/package=boinet
Licenses: Expat
Build system: r
Synopsis: Conduct Simulation Study of Bayesian Optimal Interval Design with BOIN-ET Family
Description:

Bayesian optimal interval based on both efficacy and toxicity outcomes (BOIN-ET) design is a model-assisted oncology phase I/II trial design, aiming to establish an optimal biological dose accounting for efficacy and toxicity in the framework of dose-finding. Some extensions of BOIN-ET design are also available to allow for time-to-event efficacy and toxicity outcomes based on cumulative and pending data (time-to-event BOIN-ET: TITE-BOIN-ET), ordinal graded efficacy and toxicity outcomes (generalized BOIN-ET: gBOIN-ET), and their combination (TITE-gBOIN-ET). boinet is a package to implement the BOIN-ET design family and supports the conduct of simulation studies to assess operating characteristics of BOIN-ET, TITE-BOIN-ET, gBOIN-ET, and TITE-gBOIN-ET, where users can choose design parameters in flexible and straightforward ways depending on their own application.

Total packages: 1