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r-crisprscore 1.14.0
Propagated dependencies: r-xvector@0.50.0 r-stringr@1.6.0 r-reticulate@1.44.1 r-randomforest@4.7-1.2 r-iranges@2.44.0 r-crisprscoredata@1.14.0 r-biostrings@2.78.0 r-biocgenerics@0.56.0 r-basilisk@1.22.0
Channel: guix-bioc
Location: guix-bioc/packages/c.scm (guix-bioc packages c)
Home page: https://github.com/crisprVerse/crisprScore/issues
Licenses: Expat
Synopsis: On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs
Description:

This package provides R wrappers of several on-target and off-target scoring methods for CRISPR guide RNAs (gRNAs). The following nucleases are supported: SpCas9, AsCas12a, enAsCas12a, and RfxCas13d (CasRx). The available on-target cutting efficiency scoring methods are RuleSet1, Azimuth, DeepHF, DeepCpf1, enPAM+GB, and CRISPRscan. Both the CFD and MIT scoring methods are available for off-target specificity prediction. The package also provides a Lindel-derived score to predict the probability of a gRNA to produce indels inducing a frameshift for the Cas9 nuclease. Note that DeepHF, DeepCpf1 and enPAM+GB are not available on Windows machines.

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