_            _    _        _         _
      /\ \         /\ \ /\ \     /\_\      / /\
      \_\ \       /  \ \\ \ \   / / /     / /  \
      /\__ \     / /\ \ \\ \ \_/ / /     / / /\ \__
     / /_ \ \   / / /\ \ \\ \___/ /     / / /\ \___\
    / / /\ \ \ / / /  \ \_\\ \ \_/      \ \ \ \/___/
   / / /  \/_// / /   / / / \ \ \        \ \ \
  / / /      / / /   / / /   \ \ \   _    \ \ \
 / / /      / / /___/ / /     \ \ \ /_/\__/ / /
/_/ /      / / /____\/ /       \ \_\\ \/___/ /
\_\/       \/_________/         \/_/ \_____\/
r-nonmem2rx 0.1.6
Propagated dependencies: r-xml2@1.3.6 r-rxode2@3.0.4 r-rcpp@1.0.13-1 r-qs@0.27.2 r-magrittr@2.0.3 r-lotri@1.0.0 r-ggplot2@3.5.1 r-ggforce@0.4.2 r-dparser@1.3.1-13 r-digest@0.6.37 r-data-table@1.16.2 r-crayon@1.5.3 r-cli@3.6.3 r-checkmate@2.3.2
Channel: guix-cran
Location: guix-cran/packages/n.scm (guix-cran packages n)
Home page: https://nlmixr2.github.io/nonmem2rx/
Licenses: GPL 3+
Synopsis: Converts 'NONMEM' Models to 'rxode2'
Description:

NONMEM has been a tool for running nonlinear mixed effects models since the 80s and is still used today (Bauer 2019 <doi:10.1002/psp4.12404>). This tool allows you to convert NONMEM models to rxode2 (Wang, Hallow and James (2016) <doi:10.1002/psp4.12052>) and with simple models nlmixr2 syntax (Fidler et al (2019) <doi:10.1002/psp4.12445>). The nlmixr2 syntax requires the residual specification to be included and it is not always translated. If available, the rxode2 model will read in the NONMEM data and compare the simulation for the population model ('PRED') individual model ('IPRED') and residual model ('IWRES') to immediately show how well the translation is performing. This saves the model development time for people who are creating an rxode2 model manually. Additionally, this package reads in all the information to allow simulation with uncertainty (that is the number of observations, the number of subjects, and the covariance matrix) with a rxode2 model. This is complementary to the babelmixr2 package that translates nlmixr2 models to NONMEM and can convert the objects converted from nonmem2rx to a full nlmixr2 fit.

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