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r-segregatr 0.4.0
Propagated dependencies: r-pedtools@2.8.0 r-pedprobr@0.9.5
Channel: guix-cran
Location: guix-cran/packages/s.scm (guix-cran packages s)
Home page: https://github.com/magnusdv/segregatr
Licenses: GPL 3
Synopsis: Segregation Analysis for Variant Interpretation
Description:

An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>. This implementation supports custom penetrance values and liability classes, and allows visualisations and robustness analysis as presented in Ratajska et al. (2023) <doi:10.1002/mgg3.2107>. See also the online app shinyseg', <https://chrcarrizosa.shinyapps.io/shinyseg>, which offers interactive segregation analysis with many additional features (Carrizosa et al. (2024) <doi:10.1093/bioinformatics/btae201>).

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