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This package provides R bindings to OpenSSL libssl and libcrypto, plus custom SSH pubkey parsers. It supports RSA, DSA and NIST curves P-256, P-384 and P-521. Cryptographic signatures can either be created and verified manually or via x509 certificates. AES block cipher is used in CBC mode for symmetric encryption; RSA for asymmetric (public key) encryption. High-level envelope functions combine RSA and AES for encrypting arbitrary sized data. Other utilities include key generators, hash functions (md5, sha1, sha256, etc), base64 encoder, a secure random number generator, and bignum math methods for manually performing crypto calculations on large multibyte integers.
This package provides some easy-to-use functions to extract and visualize the output of multivariate data analyses, including PCA (Principal Component Analysis), CA (Correspondence Analysis), MCA (Multiple Correspondence Analysis), FAMD (Factor Analysis of Mixed Data), MFA (Multiple Factor Analysis) and HMFA (Hierarchical Multiple Factor Analysis) functions from different R packages. It contains also functions for simplifying some clustering analysis steps and provides ggplot2-based elegant data visualization.
This library lets you place an exclusive or shared lock on a file using the appropriate system call provided by the underlying operating system.
This package provides tools for the analysis and visualization of bilateral asymmetry in parasitic infections.
This package provides for uniform handling of R's different time-based data classes by extending zoo, maximizing native format information preservation and allowing for user-level customization and extension, while simplifying cross-class interoperability.
This package provides color palettes. They are checked for colorblind accessibility from hue, saturation, and lightness value scaling using the Chroma.js Color Palette Helper. See https://gka.github.io/palettes.
This package lets you easily use Bootstrap icons inside Shiny apps and R Markdown documents. More generally, icons can be inserted in any htmltools document through inline SVG.
This package provides p-values in type I, II or III anova and summary tables for lmer model fits via Satterthwaite's degrees of freedom method. A Kenward-Roger method is also available via the pbkrtest package. Model selection methods include step, drop1 and anova-like tables for random effects (ranova). Methods for Least-Square means (LS-means) and tests of linear contrasts of fixed effects are also available.
This package provides a collection of HTML, JavaScript, and CSS assets that dynamically generate beautiful documentation from a Swagger compliant API.
This package provides a reticulate wrapper for the Python package anndata. It provides a scalable way of keeping track of data and learned annotations. It is used to read from and write to the h5ad file format.
This package provides the header files for a stripped-down version of the plog header-only C++ logging library, and a method to log to R's standard error stream.
The nls.lm function provides an R interface to lmder and lmdif from the MINPACK library, for solving nonlinear least-squares problems by a modification of the Levenberg-Marquardt algorithm, with support for lower and upper parameter bounds. The implementation can be used via nls-like calls using the nlsLM function.
The tidy modeling "verse" is a collection of packages for modeling and statistical analysis that share the underlying design philosophy, grammar, and data structures of the tidyverse.
This R package provides access to the code and data sets published by the statistics blog FiveThirtyEight.
This package provides statistical tools for Bayesian structure learning in undirected graphical models for continuous, discrete, and mixed data. It uses a trans-dimensional Markov Chain Monte Carlo (MCMC) approach based on a continuous-time birth-death process.
This package provides a syntax highlighter for R code based on the results of the R parser. It supports rendering in HTML and LaTeX markup. It includes a custom Sweave driver performing syntax highlighting of R code chunks.
This package provides a method to test genetic linkage with covariates by regression methods with response IBD sharing for relative pairs. Account for correlations of IBD statistics and covariates for relative pairs within the same pedigree.
This package provides datasets associated with the gap package. Currently, it includes an example data for regional association plot (CDKN), an example data for a genomewide association meta-analysis (OPG), data in studies of Parkinson's diease (PD), ALHD2 markers and alcoholism (aldh2), APOE/APOC1 markers and Schizophrenia (apoeapoc), cystic fibrosis (cf), a Olink/INF panel (inf1), Manhattan plots with (hr1420, mhtdata) and without (w4) gene annotations.
This package provides a wrapper around the C++ library polylabel from Mapbox, providing an efficient routine for finding the approximate pole of inaccessibility of a polygon, which usually serves as an excellent candidate for labeling of a polygon.
This package provides a new object oriented programming system designed to be a successor to S3 and S4. It includes formal class, generic, and method specification, and a limited form of multiple dispatch. It has been designed and implemented collaboratively by the R Consortium Object-Oriented Programming Working Group, which includes representatives from R-Core, Bioconductor, Posit/tidyverse, and the wider R community.
This package offers an implementation of the Abnormal blood profile score (ABPS). The ABPS is a part of the Athlete biological passport program of the World anti-doping agency, which combines several blood parameters into a single score in order to detect blood doping. The package also contains functions to calculate other scores used in anti-doping programs, such as the ratio of hemoglobin to reticulocytes (OFF-score), as well as example data.
This package provides a mutation analysis tool that discovers cancer driver genes with frequent mutations in protein signalling sites such as post-translational modifications (phosphorylation, ubiquitination, etc). The Poisson generalized linear regression model identifies genes where cancer mutations in signalling sites are more frequent than expected from the sequence of the entire gene. Integration of mutations with signalling information helps find new driver genes and propose candidate mechanisms to known drivers.
This package includes functions for processing GeoJson objects relying on RFC 7946. The geojson encoding is based on json11, a tiny JSON library for C++11. Furthermore, the source code is exported in R through the Rcpp and RcppArmadillo packages.
Regression methods to quantify the relation between two measurement methods are provided by this package. In particular it addresses regression problems with errors in both variables and without repeated measurements. It implements the CLSI recommendations (see J. A. Budd et al. (2018, https://clsi.org/standards/products/method-evaluation/documents/ep09/) for analytical method comparison and bias estimation using patient samples. Furthermore, algorithms for Theil-Sen and equivariant Passing-Bablok estimators are implemented, see F. Dufey (2020, <doi:10.1515/ijb-2019-0157>) and J. Raymaekers and F. Dufey (2022, <arXiv:2202:08060>). A comprehensive overview over the implemented methods and references can be found in the manual pages mcr-package and mcreg.