Various estimators of causal effects based on inverse probability weighting, doubly robust estimation, and double machine learning. Specifically, the package includes methods for estimating average treatment effects, direct and indirect effects in causal mediation analysis, and dynamic treatment effects. The models refer to studies of Froelich (2007) <doi:10.1016/j.jeconom.2006.06.004>, Huber (2012) <doi:10.3102/1076998611411917>, Huber (2014) <doi:10.1080/07474938.2013.806197>, Huber (2014) <doi:10.1002/jae.2341>, Froelich and Huber (2017) <doi:10.1111/rssb.12232>, Hsu, Huber, Lee, and Lettry (2020) <doi:10.1002/jae.2765>, and others.

This package provides a framework that facilitates spatio-temporal analysis of climate dynamics through exploring and measuring different dimensions of climate change in space and time.

Copernicus Digital Elevation Model datasets (DEM) of 90 and 30 meters resolution using the awscli command line tool. The Copernicus (DEM) is included in the Registry of Open Data on AWS (Amazon Web Services) and represents the surface of the Earth including buildings, infrastructure and vegetation.

Based on Dutta et al. (2018) <doi:10.1016/j.jempfin.2018.02.004>, this package provides their standardized test for abnormal returns in long-horizon event studies. The methods used improve the major weaknesses of size, power, and robustness of long-run statistical tests described in Kothari/Warner (2007) <doi:10.1016/B978-0-444-53265-7.50015-9>. Abnormal returns are weighted by their statistical precision (i.e., standard deviation), resulting in abnormal standardized returns. This procedure efficiently captures the heteroskedasticity problem. Clustering techniques following Cameron et al. (2011) <doi:10.1198/jbes.2010.07136> are adopted for computing cross-sectional correlation robust standard errors. The statistical tests in this package therefore accounts for potential biases arising from returns cross-sectional correlation, autocorrelation, and volatility clustering without power loss.

This package provides a fast, flexible and transparent framework to estimate context-specific word and short document embeddings using the a la carte embeddings approach developed by Khodak et al. (2018) <doi:10.48550/arXiv.1805.05388> and evaluate hypotheses about covariate effects on embeddings using the regression framework developed by Rodriguez et al. (2021)<doi:10.1017/S0003055422001228>. New version of the package applies a new estimator to measure the distance between word embeddings as described in Green et al. (2025) <doi:10.1017/pan.2024.22>.

Tests, utilities, and case studies for analyzing significance in clustered binary matched-pair data. The central function clust.bin.pair uses one of several tests to calculate a Chi-square statistic. Implemented are the tests Eliasziw (1991) <doi:10.1002/sim.4780101211>, Obuchowski (1998) <doi:10.1002/(SICI)1097-0258(19980715)17:13%3C1495::AID-SIM863%3E3.0.CO;2-I>, Durkalski (2003) <doi:10.1002/sim.1438>, and Yang (2010) <doi:10.1002/bimj.201000035> with McNemar (1947) <doi:10.1007/BF02295996> included for comparison. The utility functions nested.to.contingency and paired.to.contingency convert data between various useful formats. Thyroids and psychiatry are the canonical datasets from Obuchowski and Petryshen (1989) <doi:10.1016/0165-1781(89)90196-0> respectively.

This package provides a spatiotemperal data object in a relational data structure to separate the recording of time variant/ invariant variables. See the Journal of Statistical Software reference: <doi:10.18637/jss.v110.i07>.

Use three methods to estimate parameters from a mediation analysis with a binary misclassified mediator. These methods correct for the problem of "label switching" using Youden's J criteria. A detailed description of the analysis methods is available in Webb and Wells (2024), "Effect estimation in the presence of a misclassified binary mediator" <doi:10.48550/arXiv.2407.06970>.

The COVID Symptom Study is a non-commercial project that uses a free mobile app to facilitate real-time data collection of symptoms, exposures, and risk factors related to COVID19. The package allows easy access to summary statistics data from COVID Symptom Study Sweden.

Extends the functionality of base R lists and provides specialized data structures deque', set', dict', and dict.table', the latter to extend the data.table package.

Perform sparse estimation of a Gaussian graphical model (GGM) with node aggregation through variable clustering. Currently, the package implements the clusterpath estimator of the Gaussian graphical model (CGGM) (Touw, Alfons, Groenen & Wilms, 2025; <doi:10.48550/arXiv.2407.00644>).

Generate random numbers from the Cryptographically Secure Pseudorandom Number Generator (CSPRNG) provided by the underlying operating system. System CSPRNGs are seeded internally by the OS with entropy it gathers from the system hardware. The following system functions are used: arc4random_buf() on macOS and BSD; BCryptgenRandom() on Windows; Sys_getrandom() on Linux.

Tests on properties of space-time covariance functions. Tests on symmetry, separability and for assessing different forms of non-separability are available. Moreover tests on some classes of covariance functions, such that the classes of product-sum models, Gneiting models and integrated product models have been provided. It is the companion R package to the papers of Cappello, C., De Iaco, S., Posa, D., 2018, Testing the type of non-separability and some classes of space-time covariance function models <doi:10.1007/s00477-017-1472-2> and Cappello, C., De Iaco, S., Posa, D., 2020, covatest: an R package for selecting a class of space-time covariance functions <doi:10.18637/jss.v094.i01>.

Estimate bivariate common mean vector under copula models with known correlation. In the current version, available copulas are the Clayton, Gumbel, Frank, Farlie-Gumbel-Morgenstern (FGM), and normal copulas. See Shih et al. (2019) <doi:10.1080/02331888.2019.1581782> and Shih et al. (2021) <under review> for details under the FGM and general copulas, respectively.

This package provides tools for the fitting and cross validation of exact conditional logistic regression models with lasso and elastic net penalties. Uses cyclic coordinate descent and warm starts to compute the entire path efficiently.

This package implements algorithms for analyzing Cayley graphs of permutation groups, with a focus on the TopSpin puzzle and similar permutation-based combinatorial puzzles. Provides methods for cycle detection, state space exploration, and finding optimal operation sequences in permutation groups generated by shift and reverse operations.

Calculate confidence and consistency that measure the goodness-of-fit and transferability of predictive/potential distribution models (including species distribution models) as described by Somodi & Bede-Fazekas et al. (2024) <doi:10.1016/j.ecolmodel.2024.110667>.

This package contains the R functions needed to perform Cluster-Of-Clusters Analysis (COCA) and Consensus Clustering (CC). For further details please see Cabassi and Kirk (2020) <doi:10.1093/bioinformatics/btaa593>.

Plot confidence interval from the objects of statistical tests such as t.test(), var.test(), cor.test(), prop.test() and fisher.test() ('htest class), Tukey test [TukeyHSD()], Dunnett test [glht() in multcomp package], logistic regression [glm()], and Tukey or Games-Howell test [posthocTGH() in userfriendlyscience package]. Users are able to set the styles of lines and points. This package contains the function to calculate odds ratios and their confidence intervals from the result of logistic regression.

This package provides a new method for interpretable heterogeneous treatment effects characterization in terms of decision rules via an extensive exploration of heterogeneity patterns by an ensemble-of-trees approach, enforcing high stability in the discovery. It relies on a two-stage pseudo-outcome regression, and it is supported by theoretical convergence guarantees. Bargagli-Stoffi, F. J., Cadei, R., Lee, K., & Dominici, F. (2023) Causal rule ensemble: Interpretable Discovery and Inference of Heterogeneous Treatment Effects. arXiv preprint <doi:10.48550/arXiv.2009.09036>.

Provide step by step guided tours of Shiny applications.

Calculates power for assessment of intermediate biomarker responses as correlates of risk in the active treatment group in clinical efficacy trials, as described in Gilbert, Janes, and Huang, Power/Sample Size Calculations for Assessing Correlates of Risk in Clinical Efficacy Trials (2016, Statistics in Medicine). The methods differ from past approaches by accounting for the level of clinical treatment efficacy overall and in biomarker response subgroups, which enables the correlates of risk results to be interpreted in terms of potential correlates of efficacy/protection. The methods also account for inter-individual variability of the observed biomarker response that is not biologically relevant (e.g., due to technical measurement error of the laboratory assay used to measure the biomarker response), which is important because power to detect a specified correlate of risk effect size is heavily affected by the biomarker's measurement error. The methods can be used for a general binary clinical endpoint model with a univariate dichotomous, trichotomous, or continuous biomarker response measured in active treatment recipients at a fixed timepoint after randomization, with either case-cohort Bernoulli sampling or case-control without-replacement sampling of the biomarker (a baseline biomarker is handled as a trivial special case). In a specified two-group trial design, the computeN() function can initially be used for calculating additional requisite design parameters pertaining to the target population of active treatment recipients observed to be at risk at the biomarker sampling timepoint. Subsequently, the power calculation employs an inverse probability weighted logistic regression model fitted by the tps() function in the osDesign package. Power results as well as the relationship between the correlate of risk effect size and treatment efficacy can be visualized using various plotting functions. To link power calculations for detecting a correlate of risk and a correlate of treatment efficacy, a baseline immunogenicity predictor (BIP) can be simulated according to a specified classification rule (for dichotomous or trichotomous BIPs) or correlation with the biomarker response (for continuous BIPs), then outputted along with biomarker response data under assignment to treatment, and clinical endpoint data for both treatment and placebo groups.

Interact with Condor from R via SSH connection. Files are first uploaded from user machine to submitter machine, and the job is then submitted from the submitter machine to Condor'. Functions are provided to submit, list, and download Condor jobs from R. Condor is an open source high-throughput computing software framework for distributed parallelization of computationally intensive tasks.

This package performs a series of offline and/or online change-point detection algorithms for 1) univariate mean: <doi:10.1214/20-EJS1710>, <arXiv:2006.03283>; 2) univariate polynomials: <doi:10.1214/21-EJS1963>; 3) univariate and multivariate nonparametric settings: <doi:10.1214/21-EJS1809>, <doi:10.1109/TIT.2021.3130330>; 4) high-dimensional covariances: <doi:10.3150/20-BEJ1249>; 5) high-dimensional networks with and without missing values: <doi:10.1214/20-AOS1953>, <arXiv:2101.05477>, <arXiv:2110.06450>; 6) high-dimensional linear regression models: <arXiv:2010.10410>, <arXiv:2207.12453>; 7) high-dimensional vector autoregressive models: <arXiv:1909.06359>; 8) high-dimensional self exciting point processes: <arXiv:2006.03572>; 9) dependent dynamic nonparametric random dot product graphs: <arXiv:1911.07494>; 10) univariate mean against adversarial attacks: <arXiv:2105.10417>.