Computes a confidence interval for a specified linear combination of the regression parameters in a linear regression model with iid normal errors with known variance when there is uncertain prior information that a distinct specified linear combination of the regression parameters takes a given value. This confidence interval, found by numerical nonlinear constrained optimization, has the required minimum coverage and utilizes this uncertain prior information through desirable expected length properties. This confidence interval has the following three practical applications. Firstly, if the error variance has been accurately estimated from previous data then it may be treated as being effectively known. Secondly, for sufficiently large (dimension of the response vector) minus (dimension of regression parameter vector), greater than or equal to 30 (say), if we replace the assumed known value of the error variance by its usual estimator in the formula for the confidence interval then the resulting interval has, to a very good approximation, the same coverage probability and expected length properties as when the error variance is known. Thirdly, some more complicated models can be approximated by the linear regression model with error variance known when certain unknown parameters are replaced by estimates. This confidence interval is described in Mainzer, R. and Kabaila, P. (2019) <doi:10.32614/RJ-2019-026>, and is a member of the family of confidence intervals proposed by Kabaila, P. and Giri, K. (2009) <doi:10.1016/j.jspi.2009.03.018>.

Estimation of changepoints using an "S-curve" approximation. Formation of confidence intervals for changepoint locations and magnitudes. Both abrupt and gradual changes can be modeled.

Solves optimal pairing and matching problems using linear assignment algorithms. Provides implementations of the Hungarian method (Kuhn 1955) <doi:10.1002/nav.3800020109>, Jonker-Volgenant shortest path algorithm (Jonker and Volgenant 1987) <doi:10.1007/BF02278710>, Auction algorithm (Bertsekas 1988) <doi:10.1007/BF02186476>, cost-scaling (Goldberg and Kennedy 1995) <doi:10.1007/BF01585996>, scaling algorithms (Gabow and Tarjan 1989) <doi:10.1137/0218069>, push-relabel (Goldberg and Tarjan 1988) <doi:10.1145/48014.61051>, and Sinkhorn entropy-regularized transport (Cuturi 2013) <doi:10.48550/arxiv.1306.0895>. Designed for matching plots, sites, samples, or any pairwise optimization problem. Supports rectangular matrices, forbidden assignments, data frame inputs, batch solving, k-best solutions, and pixel-level image morphing for visualization. Includes automatic preprocessing with variable health checks, multiple scaling methods (standardized, range, robust), greedy matching algorithms, and comprehensive balance diagnostics for assessing match quality using standardized differences and distribution comparisons.

Generates synthetic data distributions to enable testing various modelling techniques in ways that real data does not allow. Noise can be added in a controlled manner such that the data seems real. This methodology is generic and therefore benefits both the academic and industrial research.

Statistical summary of STRUCTURE output. STRUCTURE is a K-means clustering method for inferring population structure and assigning individuals to populations using genetic data. Pritchard JK, Stephens M, Donnelly PJ (2000) <DOI:10.1093/genetics/155.2.945>. <https://web.stanford.edu/group/pritchardlab/structure.html>.

This package provides tools for downloading, reading and analyzing the COVID19 National Household Sample Survey - PNAD COVID19, a household survey from Brazilian Institute of Geography and Statistics - IBGE. The data must be downloaded from the official website <https://www.ibge.gov.br/>. Further analysis must be made using package survey'.

Hansen's (1995) Covariate-Augmented Dickey-Fuller (CADF) test. The only required argument is y, the Tx1 time series to be tested. If no stationary covariate X is passed to the procedure, then an ordinary ADF test is performed. The p-values of the test are computed using the procedure illustrated in Lupi (2009).

Statistical downscaling and bias correction of climate predictions. It includes implementations of commonly used methods such as Analogs, Linear Regression, Logistic Regression, and Bias Correction techniques, as well as interpolation functions for regridding and point-based applications. It facilitates the production of high-resolution and local-scale climate information from coarse-scale predictions, which is essential for impact analyses. The package can be applied in a wide range of sectors and studies, including agriculture, water management, energy, heatwaves, and other climate-sensitive applications. The package was developed within the framework of the European Union Horizon Europe projects Impetus4Change (101081555) and ASPECT (101081460), the Wellcome Trust supported HARMONIZE project (224694/Z/21/Z), and the Spanish national project BOREAS (PID2022-140673OA-I00). Implements the methods described in Duzenli et al. (2024) <doi:10.5194/egusphere-egu24-19420>.

This package provides a minimum set of functions to perform compositional data analysis using the log-ratio approach introduced by John Aitchison (1982). Main functions have been implemented in c++ for better performance.

Summarise and visualise the characteristics of patients in data mapped to the Observational Medical Outcomes Partnership (OMOP) common data model (CDM).

Computerized tomography (CT) can be used to assess certain wood properties when wood disks or logs are scanned. Wood density profiles (i.e. variations of wood density from pith to bark) can yield important information used for studies in forest resource assessment, wood quality and dendrochronology studies. The first step consists in transforming grey values from the scan images to density values. The packages then proposes a unique method to automatically locate the pith by combining an adapted Hough Transform method and a one-dimensional edge detector. Tree ring profiles (average ring density, earlywood and latewood density, ring width and percent latewood for each ring) are then obtained.

Can take in images in either .jpg, .jpeg, or .png format and creates a colour palette of the most frequent colours used in the image. Also provides some custom colour palettes.

This package provides a framework for modeling relationships between functional traits and both quantitative and qualitative environmental variables at the community level. It includes tools for trait binning, likelihood-based environmental estimation, model evaluation, fossil projection into modern ecometric space, and result visualization. For more details see Vermillion et al. (2018) <doi:10.1007/978-3-319-94265-0_17>, Polly et al. (2011) <doi:10.1098/rspb.2010.2233> and Polly and Head (2015) <doi:10.1017/S1089332600002953>.

Calculate the distribution of costs for the installation of an elevator based on the different distribution rules.

This package performs survival analysis using general non-linear models. Risk models can be the sum or product of terms. Each term is the product of exponential/linear functions of covariates. Additionally sub-terms can be defined as a sum of exponential, linear threshold, and step functions. Cox Proportional hazards <https://en.wikipedia.org/wiki/Proportional_hazards_model>, Poisson <https://en.wikipedia.org/wiki/Poisson_regression>, and Fine-Gray competing risks <https://www.publichealth.columbia.edu/research/population-health-methods/competing-risk-analysis> regression are supported. This work was sponsored by NASA Grants 80NSSC19M0161 and 80NSSC23M0129 through a subcontract from the National Council on Radiation Protection and Measurements (NCRP). The computing for this project was performed on the Beocat Research Cluster at Kansas State University, which is funded in part by NSF grants CNS-1006860, EPS-1006860, EPS-0919443, ACI-1440548, CHE-1726332, and NIH P20GM113109.

The Core Microbiome refers to the group of microorganisms that are consistently present in a particular environment, habitat, or host species. These microorganisms play a crucial role in the functioning and stability of that ecosystem. Identifying these microorganisms can contribute to the emerging field of personalized medicine. The CoreMicrobiomeR is designed to facilitate the identification, statistical testing, and visualization of this group of microorganisms.This package offers three key functions to analyze and visualize microbial community data. This package has been developed based on the research papers published by Pereira et al.(2018) <doi:10.1186/s12864-018-4637-6> and Beule L, Karlovsky P. (2020) <doi:10.7717/peerj.9593>.

Defines classes and methods to cross-validate various binary classification algorithms used for "class prediction" problems.

Design, workflow and statistical analysis of Cluster Randomised Trials of (health) interventions where there may be spillover between the arms (see <https://thomasasmith.github.io/index.html>).

This package provides different datasets parsed from Drugbank <https://www.drugbank.ca/covid-19> database using dbparser package. It is a smaller version from dbdataset package. It contains only information about COVID-19 possible treatment.

Detection of change-points for variance of heteroscedastic Gaussian variables with piecewise constant variance function. Adelfio, G. (2012), Change-point detection for variance piecewise constant models, Communications in Statistics, Simulation and Computation, 41:4, 437-448, <doi:10.1080/03610918.2011.592248>.

Reads and writes CSV with selected conventions. Uses the same generic function for reading and writing to promote consistent formats.

This package provides functions to analyze coarse data. Specifically, it contains functions to (1) fit parametric accelerated failure time models to interval-censored survival time data, and (2) estimate the case-fatality ratio in scenarios with under-reporting. This package's development was motivated by applications to infectious disease: in particular, problems with estimating the incubation period and the case fatality ratio of a given disease. Sample data files are included in the package. See Reich et al. (2009) <doi:10.1002/sim.3659>, Reich et al. (2012) <doi:10.1111/j.1541-0420.2011.01709.x>, and Lessler et al. (2009) <doi:10.1016/S1473-3099(09)70069-6>.

This package provides efficient implementation of the Cross-Covariance Isolate Detect (CCID) methodology for the estimation of the number and location of multiple change-points in the second-order (cross-covariance or network) structure of multivariate, possibly high-dimensional time series. The method is motivated by the detection of change points in functional connectivity networks for functional magnetic resonance imaging (fMRI), electroencephalography (EEG), magentoencephalography (MEG) and electrocorticography (ECoG) data. The main routines in the package have been extensively tested on fMRI data. For details on the CCID methodology, please see Anastasiou et al (2022), Cross-covariance isolate detect: A new change-point method for estimating dynamic functional connectivity. Medical Image Analysis, Volume 75.

This package contains some commonly used categorical variable encoders, such as LabelEncoder and OneHotEncoder'. Inspired by the encoders implemented in Python sklearn.preprocessing package (see <http://scikit-learn.org/stable/modules/preprocessing.html>).