Analyzes spatial transcriptomic data using cells-by-genes and cell location matrices to find gene pairs that coordinate their expression between spatially adjacent cells. It enables quantitative analysis and graphical assessment of these cross-expression patterns. See Sarwar et al. (2025) <doi:10.1101/2024.09.17.613579> and <https://github.com/gillislab/CrossExpression/> for more details.

Routines for the graphical representation of correlation matrices by means of correlograms, MDS maps and biplots obtained by PCA, PFA or WALS (weighted alternating least squares); See Graffelman & De Leeuw (2023) <doi: 10.1080/00031305.2023.2186952>.

Many correlation coefficient related functions are offered, such as correlations, partial correlations and hypothesis testing using asymptotic tests and computer intensive methods (bootstrap and permutation). References include Mardia K.V., Kent J.T. and Bibby J.M. (1979). "Multivariate Analysis". ISBN: 978-0124712522. London: Academic Press and Owen A. B. (2001). "Empirical likelihood". Chapman and Hall/CRC Press. ISBN: 9781584880714.

Function using lemmatization to classify educational programs according to the CINE(Classification International Normalized of Education) for Peru.

Fast application of Continuous Wavelet Transformation ('CWT') on time series with special attention to spectroscopy. It is written using data.table and C++ language and in some functions it is possible to use parallel processing to speed-up the computation over samples. Currently, only the second derivative of a Gaussian wavelet function is implemented.

This package provides color palettes based on crayon colors since the early 1900s. Colors are based on various crayon colors, sets, and promotional palettes, most of which can be found at <https://en.wikipedia.org/wiki/List_of_Crayola_crayon_colors>. All palettes are discrete palettes and are not necessarily color-blind friendly. Provides scales for ggplot2 for discrete coloring.

Seek the significant cutoff value for a continuous variable, which will be transformed into a classification, for linear regression, logistic regression, logrank analysis and cox regression. First of all, all combinations will be gotten by combn() function. Then n.per argument, abbreviated of total number percentage, will be used to remove the combination of smaller data group. In logistic, Cox regression and logrank analysis, we will also use p.per argument, patient percentage, to filter the lower proportion of patients in each group. Finally, p value in regression results will be used to get the significant combinations and output relevant parameters. In this package, there is no limit to the number of cutoff points, which can be 1, 2, 3 or more. Still, we provide 2 methods, typical Bonferroni and Duglas G (1994) <doi: 10.1093/jnci/86.11.829>, to adjust the p value, Missing values will be deleted by na.omit() function before analysis.

This package provides a covariate-augmented overdispersed Poisson factor model is proposed to jointly perform a high-dimensional Poisson factor analysis and estimate a large coefficient matrix for overdispersed count data. More details can be referred to Liu et al. (2024) <doi:10.1093/biomtc/ujae031>.

Identification and network inference of genetic loci associated with correlation changes in quantitative traits (called correlated trait loci, CTLs). Arends et al. (2016) <doi:10.21105/joss.00087>.

Simulates parameterized single- and double-directional stem deformations in tree point clouds derived from terrestrial or mobile laser scanning, enabling the generation of realistic synthetic datasets for training and validating machine learning models in wood defect detection, quality assessment, and precision forestry. For more details see Pires (2025) <doi:10.54612/a.7hln0kr0ta>.

Users can declare causal models over binary nodes, update beliefs about causal types given data, and calculate arbitrary queries. Updating is implemented in stan'. See Humphreys and Jacobs, 2023, Integrated Inferences (<DOI: 10.1017/9781316718636>) and Pearl, 2009 Causality (<DOI:10.1017/CBO9780511803161>).

Estimation of changepoints using an "S-curve" approximation. Formation of confidence intervals for changepoint locations and magnitudes. Both abrupt and gradual changes can be modeled.

Reads Word documents containing incomplete bibliographic references and produces an updated file with standardized and complete references. The package provides functions to retrieve missing authors, titles, journal details, volume, issue, and page numbers. Digital object identifiers (DOIs) are retrieved using the CrossRef application programming interface (API) <https://api.crossref.org>, and references are formatted following DOI-based citation standards as described by Paskin (2010) <doi:10.1000/182> and the citation.doi.org service <https://citation.doi.org>. The package is intended to simplify reference preparation for scientific journal submissions.

Calculate various cardiovascular disease risk scores from the Framingham Heart Study (FHS), the American College of Cardiology (ACC), and the American Heart Association (AHA) as described in Dâ agostino, et al (2008) <doi:10.1161/circulationaha.107.699579>, Goff, et al (2013) <doi:10.1161/01.cir.0000437741.48606.98>, and Mclelland, et al (2015) <doi:10.1016/j.jacc.2015.08.035>, and Khan, et al (2024) <doi:10.1161/CIRCULATIONAHA.123.067626>.

This package performs adjustments of a user-supplied independence loglikelihood function using a robust sandwich estimator of the parameter covariance matrix, based on the methodology in Chandler and Bate (2007) <doi:10.1093/biomet/asm015>. This can be used for cluster correlated data when interest lies in the parameters of the marginal distributions or for performing inferences that are robust to certain types of model misspecification. Functions for profiling the adjusted loglikelihoods are also provided, as are functions for calculating and plotting confidence intervals, for single model parameters, and confidence regions, for pairs of model parameters. Nested models can be compared using an adjusted likelihood ratio test.

Common API for filtering data stored in different data models. Provides multiple filter types and reproducible R code. Works standalone or with shinyCohortBuilder as the GUI for interactive Shiny apps.

This package provides a programmatic interface to the Chromosome Counts Database (<https://ccdb.tau.ac.il/>), Rice et al. (2014) <doi:10.1111/nph.13191>. This package is part of the ROpenSci suite (<https://ropensci.org>).

This package provides a set of state-of-the-art probabilistic modeling approaches to derive estimates of individual customer lifetime values (CLV). Commonly, probabilistic approaches focus on modelling 3 processes, i.e. individuals attrition, transaction, and spending process. Latent customer attrition models, which are also known as "buy-'til-you-die models", model the attrition as well as the transaction process. They are used to make inferences and predictions about transactional patterns of individual customers such as their future purchase behavior. Moreover, these models have also been used to predict individualsâ long-term engagement in activities such as playing an online game or posting to a social media platform. The spending process is usually modelled by a separate probabilistic model. Combining these results yields in lifetime values estimates for individual customers. This package includes fast and accurate implementations of various probabilistic models for non-contractual settings (e.g., grocery purchases or hotel visits). All implementations support time-invariant covariates, which can be used to control for e.g., socio-demographics. If such an extension has been proposed in literature, we further provide the possibility to control for time-varying covariates to control for e.g., seasonal patterns. Currently, the package includes the following latent attrition models to model individuals attrition and transaction process: [1] Pareto/NBD model (Pareto/Negative-Binomial-Distribution), [2] the Extended Pareto/NBD model (Pareto/Negative-Binomial-Distribution with time-varying covariates), [3] the BG/NBD model (Beta-Gamma/Negative-Binomial-Distribution) and the [4] GGom/NBD (Gamma-Gompertz/Negative-Binomial-Distribution). Further, we provide an implementation of the Gamma/Gamma model to model the spending process of individuals.

Run computer experiments using the adaptive composite grid algorithm with a Gaussian process model. The algorithm works best when running an experiment that can evaluate thousands of points from a deterministic computer simulation. This package is an implementation of a forthcoming paper by Plumlee, Erickson, Ankenman, et al. For a preprint of the paper, contact the maintainer of this package.

Evaluation for density and distribution function of convolution of gamma distributions in R. Two related exact methods and one approximate method are implemented with efficient algorithm and C++ code. A quick guide for choosing correct method and usage of this package is given in package vignette. For the detail of methods used in this package, we refer the user to Mathai(1982)<doi:10.1007/BF02481056>, Moschopoulos(1984)<doi:10.1007/BF02481123>, Barnabani(2017)<doi:10.1080/03610918.2014.963612>, Hu et al.(2020)<doi:10.1007/s00180-019-00924-9>.

This package provides functions to work with data frames to prepare data for further analysis. The functions for imputation, encoding, partitioning, and other manipulation can produce log files to keep track of process.

This package provides a dashboard supports the usage of cromwell'. Cromwell is a scientific workflow engine for command line users. This package utilizes cromwell REST APIs and provides these convenient functions: timing diagrams for running workflows, cromwell engine status, a tabular workflow list. For more information about cromwell', visit <http://cromwell.readthedocs.io>.

This package implements the chain binomial model for analysis of infectious disease data. Contains functions for calculating probabilities of the final size of infectious disease outbreaks using the method from D. Ludwig (1975) <doi:10.1016/0025-5564(75)90119-4> and for outbreaks that are not concluded, from Lindstrøm et al. (2024) <doi:10.48550/arXiv.2403.03948>. The package also contains methods for estimation and regression analysis of secondary attack rates.

Determining the value of Stirling numbers of 1st kind and 2nd kind,references: Bóna,Miklós(2017,ISBN 9789813148840).