Nonparametric estimator of the cumulative incidences of competing risks under double truncation. The estimator generalizes the Efron-Petrosian NPMLE (Non-Parametric Maximun Likelihood Estimator) to the competing risks setting. Efron, B. and Petrosian, V. (1999) <doi:10.2307/2669997>.

This package provides a fully native R deep learning framework for constructing, training, evaluating, and inspecting Deep Dynamic Ensemble Self Organizing Neural Networks at research scale. The core engine is an object oriented R6 class-based implementation with explicit control over layer layout, dimensional flow, forward propagation, back propagation, and transparent optimizer state updates. The framework does not rely on external deep learning back ends, enabling direct inspection of model state, reproducible numerical behavior, and fine grained architectural control without requiring compiled dependencies or graphics processing unit specific run times. Users can define dimension agnostic single layer or deep multi-layer networks without hard coded architecture limits, with per layer configuration vectors for activation functions, derivatives, dropout behavior, and initialization strategies automatically aligned to network depth through controlled replication or truncation. Reproducible workflows can be executed through high level helpers for fit, run, and predict across binary classification, multi-class classification, and regression modes. Training pipelines support optional self organization, adaptive learning rate behavior, and structured ensemble orchestration in which candidate models are evaluated under user specified performance metrics and selectively promoted or pruned to refine a primary ensemble, enabling controlled ensemble evolution over successive runs. Ensemble evaluation includes fused prediction strategies in which member outputs may be combined through weighted averaging, arithmetic averaging, or voting mechanisms to generate consolidated metrics for research level comparison and reproducible per-seed assessment. The framework supports multiple optimization approaches, including stochastic gradient descent, adaptive moment estimation, and look ahead methods, alongside configurable regularization controls such as L1, L2, and mixed penalties with separate weight and bias update logic. Evaluation features provide threshold tuning, relevance scoring, receiver operating characteristic and precision recall curve generation, area under curve computation, regression error diagnostics, and report ready metric outputs. The package also includes artifact path management, debug state utilities, structured run level metadata persistence capturing seeds, configuration states, thresholds, metrics, ensemble transitions, fused evaluation artifacts, and model identifiers, as well as reproducible scripts and vignettes documenting end to end experiments. Kingma and Ba (2015) <doi:10.48550/arXiv.1412.6980> "Adam: A Method for Stochastic Optimization". Hinton et al. (2012) <https://www.cs.toronto.edu/~tijmen/csc321/slides/lecture_slides_lec6.pdf> "Neural Networks for Machine Learning (RMSprop lecture notes)". Duchi et al. (2011) <https://jmlr.org/papers/v12/duchi11a.html> "Adaptive Subgradient Methods for Online Learning and Stochastic Optimization". Zeiler (2012) <doi:10.48550/arXiv.1212.5701> "ADADELTA: An Adaptive Learning Rate Method". Zhang et al. (2019) <doi:10.48550/arXiv.1907.08610> "Lookahead Optimizer: k steps forward, 1 step back". You et al. (2019) <doi:10.48550/arXiv.1904.00962> "Large Batch Optimization for Deep Learning: Training BERT in 76 minutes (LAMB)". McMahan et al. (2013) <https://research.google.com/pubs/archive/41159.pdf> "Ad Click Prediction: a View from the Trenches (FTRL-Proximal)". Klambauer et al. (2017) <https://proceedings.neurips.cc/paper/6698-self-normalizing-neural-networks.pdf> "Self-Normalizing Neural Networks (SELU)". Maas et al. (2013) <https://ai.stanford.edu/~amaas/papers/relu_hybrid_icml2013_final.pdf> "Rectifier Nonlinearities Improve Neural Network Acoustic Models (Leaky ReLU / rectifiers)".

Measurement and partitioning of diversity, based on Tsallis entropy, following Marcon and Herault (2015) <doi:10.18637/jss.v067.i08>. divent provides functions to estimate alpha, beta and gamma diversity of communities, including phylogenetic and functional diversity.

This package provides a system for combining two diagnostic tests using various approaches that include statistical and machine-learning-based methodologies. These approaches are divided into four groups: linear combination methods, non-linear combination methods, mathematical operators, and machine learning algorithms. See the <https://biotools.erciyes.edu.tr/dtComb/> website for more information, documentation, and examples.

This package provides various tools for analysing density profiles obtained by resistance drilling. It can load individual or multiple files and trim the starting and ending part of each density profile. Tools are also provided to trim profiles manually, to remove the trend from measurements using several methods, to plot the profiles and to detect tree rings automatically. Written with a focus on forestry use of resistance drilling in standing trees.

Identification of causal effects from arbitrary observational and experimental probability distributions via do-calculus and standard probability manipulations using a search-based algorithm by Tikka, Hyttinen and Karvanen (2021) <doi:10.18637/jss.v099.i05>. Allows for the presence of mechanisms related to selection bias (Bareinboim and Tian, 2015) <doi:10.1609/aaai.v29i1.9679>, transportability (Bareinboim and Pearl, 2014) <http://ftp.cs.ucla.edu/pub/stat_ser/r443.pdf>, missing data (Mohan, Pearl, and Tian, 2013) <http://ftp.cs.ucla.edu/pub/stat_ser/r410.pdf>) and arbitrary combinations of these. Also supports identification in the presence of context-specific independence (CSI) relations through labeled directed acyclic graphs (LDAG). For details on CSIs see (Corander et al., 2019) <doi:10.1016/j.apal.2019.04.004>.

This package provides a Bayesian framework for parameter inference in differential equations. This approach offers a rigorous methodology for parameter inference as well as modeling the link between unobservable model states and parameters, and observable quantities. Provides templates for the DE model, the observation model and data likelihood, and the model parameters and their prior distributions. A Markov chain Monte Carlo (MCMC) procedure processes these inputs to estimate the posterior distributions of the parameters and any derived quantities, including the model trajectories. Further functionality is provided to facilitate MCMC diagnostics and the visualisation of the posterior distributions of model parameters and trajectories.

The DImodels package is suitable for analysing data from biodiversity and ecosystem function studies using the Diversity-Interactions (DI) modelling approach introduced by Kirwan et al. (2009) <doi:10.1890/08-1684.1>. Suitable data will contain proportions for each species and a community-level response variable, and may also include additional factors, such as blocks or treatments. The package can perform data manipulation tasks, such as computing pairwise interactions (the DI_data() function), can perform an automated model selection process (the autoDI() function) and has the flexibility to fit a wide range of user-defined DI models (the DI() function).

The distributed online expectation maximization algorithms are used to solve parameters of Poisson mixture models. The philosophy of the package is described in Guo, G. (2022) <doi:10.1080/02664763.2022.2053949>.

This package performs calculations with tree taper (or stem profile) equations, including model fitting. The package implements the methods from Garcà a, O. (2015) "Dynamic modelling of tree form" <http://mcfns.net/index.php/Journal/article/view/MCFNS7.1_2>. The models are parsimonious, describe well the tree bole shape over its full length, and are consistent with wood formation mechanisms through time.

This package provides functions designed to connect disease-related differential proteins and co-expression network. It provides the basic statics analysis included t test, ANOVA analysis. The network construction is not offered by the package, you can used WGCNA package which you can learn in Peter et al. (2008) <doi:10.1186/1471-2105-9-559>. It also provides module analysis included PCA analysis, two enrichment analysis, Planner maximally filtered graph extraction and hub analysis.

S4-classes and methods for distributions.

This package provides wrapper of various machine learning models. In applied machine learning, there is a strong belief that we need to strike a balance between interpretability and accuracy. However, in field of the interpretable machine learning, there are more and more new ideas for explaining black-box models, that are implemented in R'. DALEXtra creates DALEX Biecek (2018) <doi:10.48550/arXiv.1806.08915> explainer for many type of models including those created using python scikit-learn and keras libraries, and java h2o library. Important part of the package is Champion-Challenger analysis and innovative approach to model performance across subsets of test data presented in Funnel Plot.

Dynamic stochastic block model that combines a stochastic block model (SBM) for its static part with independent Markov chains for the evolution of the nodes groups through time, developed in Matias and Miele (2016) <doi:10.1111/rssb.12200>.

There are many different formats dates are commonly represented with: the order of day, month, or year can differ, different separators ("-", "/", or whitespace) can be used, months can be numerical, names, or abbreviations and year given as two digits or four. datefixR takes dates in all these different formats and converts them to R's built-in date class. If datefixR cannot standardize a date, such as because it is too malformed, then the user is told which date cannot be standardized and the corresponding ID for the row. datefixR also allows the imputation of missing days and months with user-controlled behavior.

Fast C++ implementation of Dynamic Time Warping for time series dissimilarity analysis, with applications in environmental monitoring and sensor data analysis, climate science, signal processing and pattern recognition, and financial data analysis. Built upon the ideas presented in Benito and Birks (2020) <doi:10.1111/ecog.04895>, provides tools for analyzing time series of varying lengths and structures, including irregular multivariate time series. Key features include individual variable contribution analysis, restricted permutation tests for statistical significance, and imputation of missing data via GAMs. Additionally, the package provides an ample set of tools to prepare and manage time series data.

Time series analysis of network connectivity. Detects and visualizes change points between networks. Methods included in the package are discussed in depth in Baek, C., Gates, K. M., Leinwand, B., Pipiras, V. (2021) "Two sample tests for high-dimensional auto-covariances" <doi:10.1016/j.csda.2020.107067> and Baek, C., Gampe, M., Leinwand B., Lindquist K., Hopfinger J. and Gates K. (2023) â Detecting functional connectivity changes in fMRI dataâ <doi:10.1007/s11336-023-09908-7>.

Double constrained correspondence analysis (dc-CA) analyzes (multi-)trait (multi-)environment ecological data by using the vegan package and native R code. Throughout the two step algorithm of ter Braak et al. (2018) is used. This algorithm combines and extends community- (sample-) and species-level analyses, i.e. the usual community weighted means (CWM)-based regression analysis and the species-level analysis of species-niche centroids (SNC)-based regression analysis. The two steps use canonical correspondence analysis to regress the abundance data on to the traits and (weighted) redundancy analysis to regress the CWM of the orthonormalized traits on to the environmental predictors. The function dc_CA() has an option to divide the abundance data of a site by the site total, giving equal site weights. This division has the advantage that the multivariate analysis corresponds with an unweighted (multi-trait) community-level analysis, instead of being weighted. The first step of the algorithm uses vegan::cca(). The second step uses wrda() but vegan::rda() if the site weights are equal. This version has a predict() function. For details see ter Braak et al. 2018 <doi:10.1007/s10651-017-0395-x>. and ter Braak & van Rossum 2025 <doi:10.1016/j.ecoinf.2025.103143>.

Provide a Dens-based method for estimating functional connection in large scale brain networks using partial correlation.

This package contains a function called dmur() which accepts four parameters like possible values, probabilities of the values, selling cost and preparation cost. The dmur() function generates various numeric decision parameters like MEMV (Maximum (optimum) expected monitory value), best choice, EPPI (Expected profit with perfect information), EVPI (Expected value of the perfect information), EOL (Expected opportunity loss), which facilitate effective decision-making.

Diagnostics for linear L1 regression (also known as LAD - Least Absolute Deviations), including: estimation, confidence intervals, tests of hypotheses, measures of leverage, methods of diagnostics for L1 regression, special diagnostics graphs and measures of leverage. The algorithms are based in Dielman (2005) <doi:10.1080/0094965042000223680>, Elian et al. (2000) <doi:10.1080/03610920008832518> and Dodge (1997) <doi:10.1006/jmva.1997.1666>. This package builds on the quantreg package, which is a well-established package for tuning quantile regression models. There are also tests to verify if the errors have a Laplace distribution based on the work of Puig and Stephens (2000) <doi:10.2307/1270952>.

The recovery of visual sensitivity in a dark environment is known as dark adaptation. In a clinical or research setting the recovery is typically measured after a dazzling flash of light and can be described by the Mahroo, Lamb and Pugh (MLP) model of dark adaptation. The functions in this package take dark adaptation data and use nonlinear regression to find the parameters of the model that best describe the data. They do this by firstly, generating rapid initial objective estimates of data adaptation parameters, then a multi-start algorithm is used to reduce the possibility of a local minimum. There is also a bootstrap method to calculate parameter confidence intervals. The functions rely upon a dark list or object. This object is created as the first step in the workflow and parts of the object are updated as it is processed.

This package implements a generalized linear model approach for detecting differentially expressed genes across treatment groups in count data. The package supports both quasi-Poisson and negative binomial models to handle over-dispersion, ensuring robust identification of differential expression. It allows for the inclusion of treatment effects and gene-wise covariates, as well as normalization factors for accurate scaling across samples. Additionally, it incorporates statistical significance testing with options for p-value adjustment and log2 fold range thresholds, making it suitable for RNA-seq analysis as described in by Xu et al., (2024) <doi:10.1371/journal.pone.0300565>.

This package provides methods for valuation of life insurance premiums and reserves (including variable-benefit and fractional coverage) based on "Actuarial Mathematics" by Bowers, H.U. Gerber, J.C. Hickman, D.A. Jones and C.J. Nesbitt (1997, ISBN: 978-0938959465), "Actuarial Mathematics for Life Contingent Risks" by Dickson, David C. M., Hardy, Mary R. and Waters, Howard R (2009) <doi:10.1017/CBO9780511800146> and "Life Contingencies" by Jordan, C. W (1952) <doi:10.1017/S002026810005410X>. It also contains functions for equivalent interest and discount rate calculation, present and future values of annuities, and loan amortization schedule.