Simulation models (apps) of various within-host immune response scenarios. The purpose of the package is to help individuals learn about within-host infection and immune response modeling from a dynamical systems perspective. All apps include explanations of the underlying models and instructions on what to do with the models.

This package provides novel dendroclimatological methods, primarily used by the Tree-ring research community. There are four core functions. The first one is daily_response(), which finds the optimal sequence of days that are related to one or more tree-ring proxy records. Similar function is daily_response_seascorr(), which implements partial correlations in the analysis of daily response functions. For the enthusiast of monthly data, there is monthly_response() function. The last core function is compare_methods(), which effectively compares several linear and nonlinear regression algorithms on the task of climate reconstruction.

This package provides various tools for analysing density profiles obtained by resistance drilling. It can load individual or multiple files and trim the starting and ending part of each density profile. Tools are also provided to trim profiles manually, to remove the trend from measurements using several methods, to plot the profiles and to detect tree rings automatically. Written with a focus on forestry use of resistance drilling in standing trees.

Probability mass function, distribution function, quantile function, random generation and estimation for the skew discrete Laplace distributions.

This package provides a Bayesian clustering method for replicated time series or replicated measurements from multiple experimental conditions, e.g., time-course gene expression data. It estimates the number of clusters directly from the data using a Dirichlet-process prior. See Fu, A. Q., Russell, S., Bray, S. and Tavare, S. (2013) Bayesian clustering of replicated time-course gene expression data with weak signals. The Annals of Applied Statistics. 7(3) 1334-1361. <doi:10.1214/13-AOAS650>.

Package including an interactive Shiny application for plotting common univariate distributions.

We provide three distance metrics for measuring the separation between two clusters in high-dimensional spaces. The first metric is the centroid distance, which calculates the Euclidean distance between the centers of the two groups. The second is a ridge Mahalanobis distance, which incorporates a ridge correction constant, alpha, to ensure that the covariance matrix is invertible. The third metric is the maximal data piling distance, which computes the orthogonal distance between the affine spaces spanned by each class. These three distances are asymptotically interconnected and are applicable in tasks such as discrimination, clustering, and outlier detection in high-dimensional settings.

This package provides Python-based extensions to enhance data analytics workflows, particularly for tasks involving data preprocessing and predictive modeling. Includes tools for data sampling, transformation, feature selection, balancing strategies (e.g., SMOTE), and model construction. These capabilities leverage Python libraries via the reticulate interface, enabling seamless integration with a broader machine learning ecosystem. Supports instance selection and hybrid workflows that combine R and Python functionalities for flexible and reproducible analytical pipelines. The architecture is inspired by the Experiment Lines approach, which promotes modularity, extensibility, and interoperability across tools. More information on Experiment Lines is available in Ogasawara et al. (2009) <doi:10.1007/978-3-642-02279-1_20>.

This package provides a comprehensive toolkit for analyzing microscopy data output from QuPath software. Provides functionality for automated data processing, metadata extraction, and statistical analysis of imaging results. The methodology implemented in this package is based on Labrosse et al. (2024) <doi:10.1016/j.xpro.2024.103274> "Protocol for quantifying drug sensitivity in 3D patient-derived ovarian cancer models", which describes the complete workflow for drug sensitivity analysis in patient-derived cancer models.

This package performs cluster analysis using an ensemble clustering framework, Chiu & Talhouk (2018) <doi:10.1186/s12859-017-1996-y>. Results from a diverse set of algorithms are pooled together using methods such as majority voting, K-Modes, LinkCluE, and CSPA. There are options to compare cluster assignments across algorithms using internal and external indices, visualizations such as heatmaps, and significance testing for the existence of clusters.

Simultaneously detect the number and locations of change points in piecewise linear models under stationary Gaussian noise allowing autocorrelated random noise. The core idea is to transform the problem of detecting change points into the detection of local extrema (local maxima and local minima)through kernel smoothing and differentiation of the data sequence, see Cheng et al. (2020) <doi:10.1214/20-EJS1751>. A low-computational and fast algorithm call dSTEM is introduced to detect change points based on the STEM algorithm in D. Cheng and A. Schwartzman (2017) <doi:10.1214/16-AOS1458>.

The DWD provides gridded radar data for Germany in binary format. dwdradar reads these files and enables a fast conversion into numerical format.

Mapping, spatial analysis, and statistical modeling of microdata from sources such as the Demographic and Health Surveys <https://www.dhsprogram.com/> and Integrated Public Use Microdata Series <https://www.ipums.org/>. It can also be extended to other datasets. The package supports spatial correlation index construction and visualization, along with empirical Bayes approximation of regression coefficients in a multistage setup. The main functionality is repeated regression â for example, if we have to run regression for n groups, the group ID should be vertically composed into the variable for the parameter `location_var`. It can perform various kinds of regression, such as Generalized Regression Models, logit, probit, and more. Additionally, it can incorporate interaction effects. The key benefit of the package is its ability to store the regression results performed repeatedly on a dataset by the group ID, along with respective p-values and map those estimates.

This is an R implementation of Fast and Scalable Learning of Sparse Changes in High-Dimensional Gaussian Graphical Model Structure (DIFFEE). The DIFFEE algorithm can be used to fast estimate the differential network between two related datasets. For instance, it can identify differential gene network from datasets of case and control. By performing data-driven network inference from two high-dimensional data sets, this tool can help users effectively translate two aggregated data blocks into knowledge of the changes among entities between two Gaussian Graphical Model. Please run demo(diffeeDemo) to learn the basic functions provided by this package. For further details, please read the original paper: Beilun Wang, Arshdeep Sekhon, Yanjun Qi (2018) <arXiv:1710.11223>.

Various methods for the identification of trend and seasonal components in time series (TS) are provided. Among them is a data-driven locally weighted regression approach with automatically selected bandwidth for equidistant short-memory time series. The approach is a combination / extension of the algorithms by Feng (2013) <doi:10.1080/02664763.2012.740626> and Feng, Y., Gries, T., and Fritz, M. (2020) <doi:10.1080/10485252.2020.1759598> and a brief description of this new method is provided in the package documentation. Furthermore, the package allows its users to apply the base model of the Berlin procedure, version 4.1, as described in Speth (2004) <https://www.destatis.de/DE/Methoden/Saisonbereinigung/BV41-methodenbericht-Heft3_2004.pdf?__blob=publicationFile>. Permission to include this procedure was kindly provided by the Federal Statistical Office of Germany.

Interactive R tutorials and datasets for the textbook Field (2026), "Discovering Statistics Using R and RStudio", <https://www.discovr.rocks/>. Interactive tutorials cover general workflow in R and RStudio', summarizing data, visualizing data, fitting models and bias, correlation, the general linear model (GLM), moderation, mediation, missing values, comparing means using the GLM (analysis of variance), comparing adjusted means (analysis of covariance), factorial designs, multilevel models, repeated measures designs, growth models, exploratory factor analysis (EFA), loglinear analysis, and logistic regression. There are no functions, only datasets and interactive tutorials.

Estimators of Difference-in-Differences based on de Chaisemartin and D'Haultfoeuille.

Data quality assessments guided by a data quality framework introduced by Schmidt and colleagues, 2021 <doi:10.1186/s12874-021-01252-7> target the data quality dimensions integrity, completeness, consistency, and accuracy. The scope of applicable functions rests on the availability of extensive metadata which can be provided in spreadsheet tables. Either standardized (e.g. as html5 reports) or individually tailored reports can be generated. For an introduction into the specification of corresponding metadata, please refer to the package website <https://dataquality.qihs.uni-greifswald.de/VIN_Annotation_of_Metadata.html>.

The Dirichlet Laplace shrinkage prior in Bayesian linear regression and variable selection, featuring: utility functions in implementing Dirichlet-Laplace priors such as visualization; scalability in Bayesian linear regression; penalized credible regions for variable selection.

Estimates a variety of Dynamic Conditional Correlation (DCC) models. More in detail, the dccmidas package allows the estimation of the corrected DCC (cDCC) of Aielli (2013) <doi:10.1080/07350015.2013.771027>, the DCC-MIDAS of Colacito et al. (2011) <doi:10.1016/j.jeconom.2011.02.013>, the Asymmetric DCC of Cappiello et al. <doi:10.1093/jjfinec/nbl005>, and the Dynamic Equicorrelation (DECO) of Engle and Kelly (2012) <doi:10.1080/07350015.2011.652048>. dccmidas offers the possibility of including standard GARCH <doi:10.1016/0304-4076(86)90063-1>, GARCH-MIDAS <doi:10.1162/REST_a_00300> and Double Asymmetric GARCH-MIDAS <doi:10.1016/j.econmod.2018.07.025> models in the univariate estimation. Moreover, also the scalar and diagonal BEKK <doi:10.1017/S0266466600009063> models can be estimated. Finally, the package calculates also the var-cov matrix under two non-parametric models: the Moving Covariance and the RiskMetrics specifications.

The DYMO package provides tools for multi-feature time-series forecasting using a Dynamic Mode Decomposition (DMD) model combined with conformal predictive sampling for uncertainty quantification.

DataSHIELD is an infrastructure and series of R packages that enables the remote and non-disclosive analysis of sensitive research data. This package is the DataSHIELD interface implementation for Opal', which is the data integration application for biobanks by OBiBa'. Participant data, once collected from any data source, must be integrated and stored in a central data repository under a uniform model. Opal is such a central repository. It can import, process, validate, query, analyze, report, and export data. Opal is the reference implementation of the DataSHIELD infrastructure.

Create disposable R packages for testing. You can create, install and load multiple R packages with a single function call, and then unload, uninstall and destroy them with another function call. This is handy when testing how some R code or an R package behaves with respect to other packages.

The set of teacher/class lessons is completed with a column that allocates a day to each lesson, so that the distribution of lessons by day, by class, and by teacher is as uniform as possible. <https://vlad.bazon.net/>.