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An implementation of multiple-locus association mapping on a genome-wide scale. Eagle can handle inbred and outbred study populations, populations of arbitrary unknown complexity, and data larger than the memory capacity of the computer. Since Eagle is based on linear mixed models, it is best suited to the analysis of data on continuous traits. However, it can tolerate non-normal data. Eagle reports, as its findings, the best set of snp in strongest association with a trait. For users unfamiliar with R, to perform an analysis, run OpenGUI()'. This opens a web browser to the menu-driven user interface for the input of data, and for performing genome-wide analysis.
This package provides a framework to simulate ecosystem dynamics through ordinary differential equations (ODEs). You create an ODE model, tells ecode to explore its behaviour, and perform numerical simulations on the model. ecode also allows you to fit model parameters by machine learning algorithms. Potential users include researchers who are interested in the dynamics of ecological community and biogeochemical cycles.
Read in and analyze functions for education survey and assessment data from the National Center for Education Statistics (NCES) <https://nces.ed.gov/>, including National Assessment of Educational Progress (NAEP) data <https://nces.ed.gov/nationsreportcard/> and data from the International Assessment Database: Organisation for Economic Co-operation and Development (OECD) <https://www.oecd.org/>, including Programme for International Student Assessment (PISA), Teaching and Learning International Survey (TALIS), Programme for the International Assessment of Adult Competencies (PIAAC), and International Association for the Evaluation of Educational Achievement (IEA) <https://www.iea.nl/>, including Trends in International Mathematics and Science Study (TIMSS), TIMSS Advanced, Progress in International Reading Literacy Study (PIRLS), International Civic and Citizenship Study (ICCS), International Computer and Information Literacy Study (ICILS), and Civic Education Study (CivEd).
This package provides convenience functions for researching experiences including user, customer, patient, employee, and other human experiences. It provides a suite of tools to simplify data exploration such as benchmarking, comparing groups, and checking for differences. The outputs translate statistical approaches in applied experience research to human readable output.
Predicts enrollment and events assumed enrollment and treatment-specific time-to-event models, and calculates test statistics for time-to-event data with cured population based on the simulation.Methods for prediction event in the existence of cured population are as described in : Chen, Tai-Tsang(2016) <doi:10.1186/s12874-016-0117-3>.
Pacote para análise de delineamentos experimentais (DIC, DBC e DQL), experimentos em esquema fatorial duplo (em DIC e DBC), experimentos em parcelas subdivididas (em DIC e DBC), experimentos em esquema fatorial duplo com um tratamento adicional (em DIC e DBC), experimentos em fatorial triplo (em DIC e DBC) e experimentos em esquema fatorial triplo com um tratamento adicional (em DIC e DBC), fazendo analise de variancia e comparacao de multiplas medias (para tratamentos qualitativos), ou ajustando modelos de regressao ate a terceira potencia (para tratamentos quantitativos); analise de residuos (Ferreira, Cavalcanti and Nogueira, 2014) <doi:10.4236/am.2014.519280>.
Allows calculating global scores for characteristics of visual stimuli as assessed by human raters. Stimuli are presented as sequence of pairwise comparisons ('contests'), during each of which a rater expresses preference for one stimulus over the other (forced choice). The algorithm for calculating global scores is based on Elo rating, which updates individual scores after each single pairwise contest. Elo rating is widely used to rank chess players according to their performance. Its core feature is that dyadic contests with expected outcomes lead to smaller changes of participants scores than outcomes that were unexpected. As such, Elo rating is an efficient tool to rate individual stimuli when a large number of such stimuli are paired against each other in the context of experiments where the goal is to rank stimuli according to some characteristic of interest. Clark et al (2018) <doi:10.1371/journal.pone.0190393> provide details.
This package provides a system for calculating the optimal sampling effort, based on the ideas of "Ecological cost-benefit optimization" as developed by A. Underwood (1997, ISBN 0 521 55696 1). Data is obtained from simulated ecological communities with prep_data() which formats and arranges the initial data, and then the optimization follows the following procedure of four functions: (1) prep_data() takes the original dataset and creates simulated sets that can be used as a basis for estimating statistical power and type II error. (2) sim_beta() is used to estimate the statistical power for the different sampling efforts specified by the user. (3) sim_cbo() calculates then the optimal sampling effort, based on the statistical power and the sampling costs. Additionally, (4) scompvar() calculates the variation components necessary for (5) Underwood_cbo() to calculate the optimal combination of number of sites and samples depending on either an economic budget or on a desired statistical accuracy. Lastly, (6) plot_power() helps the user visualize the results of sim_beta().
Offers a set of functions to easily download and clean Brazilian electoral data from the Superior Electoral Court and CepespData websites. Among other features, the package retrieves data on local and federal elections for all positions (city councilor, mayor, state deputy, federal deputy, governor, and president) aggregated by state, city, and electoral zones.
This package performs parallel analysis (Timmerman & Lorenzo-Seva, 2011 <doi:10.1037/a0023353>) and hull method (Lorenzo-Seva, Timmerman, & Kiers, 2011 <doi:10.1080/00273171.2011.564527>) for assessing the dimensionality of a set of variables using minimum rank factor analysis (see ten Berge & Kiers, 1991 <doi:10.1007/BF02294464> for more information). The package also includes the option to compute minimum rank factor analysis by itself, as well as the greater lower bound calculation.
The basic use of this package is with 3 sequential functions. First to generate a cell mean matrix. In case of a repeated measurements design also generate correlation and covariance matrices. This is followed by iterative experiment simulation. Finally, power is calculated from the simulated data. Features that may be considered in the model are interaction, measure correlation, non-normal and unbalanced designs distributions.
Compute energy landscapes using a digital elevation model and body mass of animals.
This data management package provides some helper classes for publicly available data sources (HMD, DESTATIS) in Demography. Similar to ideas developed in the Bioconductor project <https://bioconductor.org> we strive to encapsulate data in easy to use S4 objects. If original data is provided in a text file, the resulting S4 object contains all information from that text file. But the information is somehow structured (header, footer, etc). Further the classes provide methods to make a subset for selected calendar years or selected regions. The resulting subset objects still contain the original header and footer information.
Reliable and rapid ethnicity annotation from whole exome and targeted sequencing data.
Multivariate modeling of data after deflation of interfering effects. EF Mosleth et al. (2021) <doi:10.1038/s41598-021-82388-w> and EF Mosleth et al. (2020) <doi:10.1016/B978-0-12-409547-2.14882-6>.
This package provides a small set of functions for managing R environments, with defaults designed to encourage usage patterns that scale well to larger code bases. It provides: import_from(), a flexible way to assign bindings that defaults to the current environment; include(), a vectorized alternative to base::source() that also default to the current environment; and attach_eval() and attach_source(), a way to evaluate expressions in attached environments. Together, these (and other) functions pair to provide a robust alternative to base::library() and base::source().
In personalized medicine, one wants to know, for a given patient and his or her outcome for a predictor (pre-treatment variable), how likely it is that a treatment will be more beneficial than an alternative treatment. This package allows for the quantification of the predictive causal association (i.e., the association between the predictor variable and the individual causal effect of the treatment) and related metrics. Part of this software has been developed using funding provided from the European Union's 7th Framework Programme for research, technological development and demonstration under Grant Agreement no 602552.
Fit the hierarchical and non-hierarchical Bayesian measurement models proposed by Bullock, Imai, and Shapiro (2011) <DOI:10.1093/pan/mpr031> to analyze endorsement experiments. Endorsement experiments are a survey methodology for eliciting truthful responses to sensitive questions. This methodology is helpful when measuring support for socially sensitive political actors such as militant groups. The model is fitted with a Markov chain Monte Carlo algorithm and produces the output containing draws from the posterior distribution.
Elastic net regression models are controlled by two parameters, lambda, a measure of shrinkage, and alpha, a metric defining the model's location on the spectrum between ridge and lasso regression. glmnet provides tools for selecting lambda via cross validation but no automated methods for selection of alpha. Elastic Net SearcheR automates the simultaneous selection of both lambda and alpha. Developed, in part, with support by NICHD R03 HD094912.
Efficiently impute large scale matrix with missing values via its unbiased low-rank matrix approximation. Our main approach is Hard-Impute algorithm proposed in <https://www.jmlr.org/papers/v11/mazumder10a.html>, which achieves highly computational advantage by truncated singular-value decomposition.
This package provides methods for fitting various extreme value distributions with parameters of generalised additive model (GAM) form are provided. For details of distributions see Coles, S.G. (2001) <doi:10.1007/978-1-4471-3675-0>, GAMs see Wood, S.N. (2017) <doi:10.1201/9781315370279>, and the fitting approach see Wood, S.N., Pya, N. & Safken, B. (2016) <doi:10.1080/01621459.2016.1180986>. Details of how evgam works and various examples are given in Youngman, B.D. (2022) <doi:10.18637/jss.v103.i03>.
Streamlines common steps for working with animal tracking data, from raw telemetry points to summaries, interactive maps, and home range estimates. Designed to be beginner-friendly, it enables rapid exploration of spatial and movement data with minimal wrangling, providing a unified workflow for importing, summarizing, and visualizing, and analyzing animal movement datasets.
This package implements the conditional estimation procedure of Lee, Sun, Sun and Taylor (2016) <doi:10.1214/15-AOS1371>. This procedure allows hypothesis testing on the mean of a normal random vector subject to linear constraints.
User friendly interface based on the R package gstat to fit exponential parametric models to empirical semi-variograms in order to model the spatial correlation structure of health data. Geo-located health outcomes of survey participants may be used to model spatial effects on health in an ego-centred approach. The package contains a range of functions to help explore the spatial structure of the data as well as visualize the fit of exponential models for various metaparameter combinations with respect to the number of lag intervals and maximal distance. Furthermore, the outcome of interest can be adjusted for covariates by fitting a linear regression in a preliminary step before the semi-variogram fitting process.