This package provides tools for studying genotype-phenotype maps for bi-allelic loci underlying quantitative phenotypes. The 0.1 version is released in connection with the publication of Gjuvsland et al (2013) and implements basic line plots and the monotonicity measures for GP maps presented in the paper. Reference: Gjuvsland AB, Wang Y, Plahte E and Omholt SW (2013) Monotonicity is a key feature of genotype-phenotype maps. Frontier in Genetics 4:216 <doi:10.3389/fgene.2013.00216>.

This package provides functionality to create customizable volcano plots for visualizing differential gene expression analysis results. The package offers options to highlight genes of interest, adjust significance thresholds, customize colors, and add informative labels. Designed specifically for RNA-seq data analysis workflows.

Triangular and trapezoidal fuzzy numbers are used to study fuzzy logic, fuzzy reasoning and approximating, fuzzy regression models, etc. This package builds the generating function for triangular and trapezoidal fuzzy numbers based on Souliotis et al. (2022)<doi:10.3390/math10183350>. They proposed a method for the construction of fuzzy numbers via a cumulative distribution function based on the possibility theory.

Mapping tools that convert place names to coordinates on the fly. These ggplot2 extensions make maps from a data frame where one of the columns contains place names, without having to directly work with the underlying geospatial data and tools. The corresponding map data must be registered with cartographer either by the user or by another package.

Create network-style visualizations of pairwise relationships using custom edge glyphs built on top of ggplot2'. The package supports both statistical and non-statistical data and allows users to represent directed relationships. This enables clear, publication-ready graphics for exploring and communicating relational structures in a wide range of domains. The method was first used in Abu-Akel et al. (2021) <doi:10.1371/journal.pone.0245100>. Code is released under the MIT License; included datasets are licensed under the Creative Commons Attribution 4.0 International (CC BY 4.0).

Datasets analysed in the book Antony Unwin (2024, ISBN:978-0367674007) "Getting (more out of) Graphics".

Reference datasets commonly used in the geosciences. These include standard atomic weights of the elements, a periodic table, a list of minerals including their abbreviations and chemistry, geochemical data of reservoirs (primitive mantle, continental crust, mantle, basalts, etc.), decay constants and isotopic ratios frequently used in geochronology, color codes of the chronostratigraphic chart. In addition, the package provides functions for basic queries of atomic weights, the list of minerals, and chronostratigraphic chart colors. All datasets are fully referenced, and a BibTeX file containing the references is included.

This package provides a set of high efficient functions to decode identifiers of National Football League players.

Likelihood inference in Gaussian copula marginal regression models.

This package provides a framework to assist creation of marine ecosystem models, generating either R or C++ code which can then be optimised using the TMB package and standard R tools. Principally designed to reproduce gadget2 models in TMB', but can be extended beyond gadget2's capabilities. Kasper Kristensen, Anders Nielsen, Casper W. Berg, Hans Skaug, Bradley M. Bell (2016) <doi:10.18637/jss.v070.i05> "TMB: Automatic Differentiation and Laplace Approximation.". Begley, J., & Howell, D. (2004) <https://files01.core.ac.uk/download/pdf/225936648.pdf> "An overview of Gadget, the globally applicable area-disaggregated general ecosystem toolbox. ICES.".

We provide an efficient implementation for two-step multi-source transfer learning algorithms in high-dimensional generalized linear models (GLMs). The elastic-net penalized GLM with three popular families, including linear, logistic and Poisson regression models, can be fitted. To avoid negative transfer, a transferable source detection algorithm is proposed. We also provides visualization for the transferable source detection results. The details of methods can be found in "Tian, Y., & Feng, Y. (2023). Transfer learning under high-dimensional generalized linear models. Journal of the American Statistical Association, 118(544), 2684-2697.".

This package provides a genetic algorithm for finding variable subsets in high dimensional data with high prediction performance. The genetic algorithm can use ordinary least squares (OLS) regression models or partial least squares (PLS) regression models to evaluate the prediction power of variable subsets. By supporting different cross-validation schemes, the user can fine-tune the tradeoff between speed and quality of the solution.

Datos de nombres inscritos en Chile entre 1920 y 2021, de acuerdo al Servicio de Registro Civil. English: Chilean baby names registered from 1920 to 2021 by the Civil Registry Service.

Estimation of the variogram through trimmed mean, radial basis functions (optimization, prediction and cross-validation), summary statistics from cross-validation, pocket plot, and design of optimal sampling networks through sequential and simultaneous points methods.

Set of functions for step-wise generation of (weighted) graphs. Aimed for research in the field of single- and multi-objective combinatorial optimization. Graphs are generated adding nodes, edges and weights. Each step may be repeated multiple times with different predefined and custom generators resulting in high flexibility regarding the graph topology and structure of edge weights.

Toolbox for various enrichment analysis methods and quantification of uncertainty of gene sets, Schmid et al. (2016) <doi:10.1093/bioinformatics/btw030>.

Estimates statistically significant marker combination values within which one immunologically distinctive group (i.e., disease case) is more associated than another group (i.e., healthy control), successively, using various combinations (i.e., "gates") of markers to examine features of cells that may be different between groups. For a two-group comparison, the gateR package uses the spatial relative risk function estimated using the sparr package. Details about the sparr package methods can be found in the tutorial: Davies et al. (2018) <doi:10.1002/sim.7577>. Details about kernel density estimation can be found in J. F. Bithell (1990) <doi:10.1002/sim.4780090616>. More information about relative risk functions using kernel density estimation can be found in J. F. Bithell (1991) <doi:10.1002/sim.4780101112>.

This package provides functions for the g-and-k and generalised g-and-h distributions.

Several Goodness-of-Fit (GoF) tests for Copulae are provided. A new hybrid test, Zhang et al. (2016) <doi:10.1016/j.jeconom.2016.02.017> is implemented which supports all of the individual tests in the package, e.g. Genest et al. (2009) <doi:10.1016/j.insmatheco.2007.10.005>. Estimation methods for the margins are provided and all the tests support parameter estimation and predefined values. The parameters are estimated by pseudo maximum likelihood but if it fails the estimation switches automatically to inversion of Kendall's tau. For reproducibility of results, the functions support the definition of seeds. Also all the tests support automatized parallelization of the bootstrapping tasks. The package provides an interface to perform new GoF tests by submitting the test statistic.

Providing various equations to calculate Gini coefficients. The methods used in this package can be referenced from Brown MC (1994) <doi: 10.1016/0277-9536(94)90189-9>.

Gene-Ranking Analysis of Pathway Expression (GRAPE) is a tool for summarizing the consensus behavior of biological pathways in the form of a template, and for quantifying the extent to which individual samples deviate from the template. GRAPE templates are based only on the relative rankings of the genes within the pathway and can be used for classification of tissue types or disease subtypes. GRAPE can be used to represent gene-expression samples as vectors of pathway scores, where each pathway score indicates the departure from a given collection of reference samples. The resulting pathway- space representation can be used as the feature set for various applications, including survival analysis and drug-response prediction. Users of GRAPE should use the following citation: Klein MI, Stern DF, and Zhao H. GRAPE: A pathway template method to characterize tissue-specific functionality from gene expression profiles. BMC Bioinformatics, 18:317 (June 2017).

Allows for easy creation of diagnostic plots for a variety of model objects using the Grammar of Graphics. Provides functionality for both individual diagnostic plots and an array of four standard diagnostic plots.

This package provides functions to compute various germination indices such as germinability, median germination time, mean germination time, mean germination rate, speed of germination, Timson's index, germination value, coefficient of uniformity of germination, uncertainty of germination process, synchrony of germination etc. from germination count data. Includes functions for fitting cumulative seed germination curves using four-parameter hill function and computation of associated parameters. See the vignette for more, including full list of citations for the methods implemented.

We implement various classical tests for the composite hypothesis of testing the fit to the family of gamma distributions as the Kolmogorov-Smirnov test, the Cramer-von Mises test, the Anderson Darling test and the Watson test. For each test a parametric bootstrap procedure is implemented, as considered in Henze, Meintanis & Ebner (2012) <doi:10.1080/03610926.2010.542851>. The recent procedures presented in Henze, Meintanis & Ebner (2012) <doi:10.1080/03610926.2010.542851> and Betsch & Ebner (2019) <doi:10.1007/s00184-019-00708-7> are implemented. Estimation of parameters of the gamma law are implemented using the method of Bhattacharya (2001) <doi:10.1080/00949650108812100>.