This package implements continuous-time hidden Markov models (HMMs) to infer identity-by-descent (IBD) segments shared by two individuals from their single-nucleotide polymorphism (SNP) genotypes. Provides posterior probabilities at each marker (forward-backward algorithm), prediction of IBD segments (Viterbi algorithm), and functions for visualising results. Supports both autosomal data and X-chromosomal data.

Simplifies the generation of customized R Markdown PDF templates. A template may include an individual logo, typography, geometry or color scheme. The package provides a skeleton with detailed instructions for customizations. The skeleton can be modified by changing defaults in the YAML header, by adding additional LaTeX commands or by applying dynamic adjustments in R. Individual corporate design elements, such as a title page, can be added as R functions that produce LaTeX code.

We provide the collection of data-sets used in the book An Introduction to Statistical Learning with Applications in R, Second Edition'. These include many data-sets that we used in the first edition (some with minor changes), and some new datasets.

An R implementation of Matthew Thomas's Python library inteq'. First, this solves Fredholm integral equations of the first kind ($f(s) = \int_a^b K(s, y) g(y) dy$) using methods described by Twomey (1963) <doi:10.1145/321150.321157>. Second, this solves Volterra integral equations of the first kind ($f(s) = \int_0^s K(s,y) g(t) dt$) using methods from Betto and Thomas (2021) <doi:10.48550/arXiv.2106.08496>. Third, this solves Voltera integral equations of the second kind ($g(s) = f(s) + \int_a^s K(s,y) g(y) dy$) using methods from Linz (1969) <doi:10.1137/0706034>.

Survival analysis of interval-censored data with proportional hazards, and an explicit smooth estimate of the baseline log-hazard with P-splines.

Multivariate Expectation-Maximization (EM) based imputation framework that offers several different algorithms. These include regularisation methods like Lasso and Ridge regression, tree-based models and dimensionality reduction methods like PCA and PLS.

Improve optical character recognition by binarizing images. The package focuses primarily on local adaptive thresholding algorithms. In English, this means that it has the ability to turn a color or gray scale image into a black and white image. This is particularly useful as a preprocessing step for optical character recognition or handwritten text recognition.

This package provides tools to download, process, and analyze data from the International Monetary Fund's World Economic Outlook (WEO) database <https://www.imf.org/en/Publications/SPROLLs/world-economic-outlook-databases>. Functions support downloading complete WEO releases, accessing specific economic indicators for selected countries, and listing available data.

This package provides functions to help with analysis of longitudinal data featuring irregular observation times, where the observation times may be associated with the outcome process. There are functions to quantify the degree of irregularity, fit inverse-intensity weighted Generalized Estimating Equations (Lin H, Scharfstein DO, Rosenheck RA (2004) <doi:10.1111/j.1467-9868.2004.b5543.x>), perform multiple outputation (Pullenayegum EM (2016) <doi:10.1002/sim.6829>) and fit semi-parametric joint models (Liang Y (2009) <doi: 10.1111/j.1541-0420.2008.01104.x>).

General purpose TIFF file I/O for R users. Currently the only such package with read and write support for TIFF files with floating point (real-numbered) pixels, and the only package that can correctly import TIFF files that were saved from ImageJ and write TIFF files than can be correctly read by ImageJ <https://imagej.net/ij/>. Also supports text image I/O.

Data from the United States Center for Medicare and Medicaid Services (CMS) is included in this package. There are ICD-9 and ICD-10 diagnostic and procedure codes, and lists of the chapter and sub-chapter headings and the ranges of ICD codes they encompass. There are also two sample datasets. These data are used by the icd package for finding comorbidities.

Computes bootstrapped Monte Carlo estimate of p value of Kolmogorov-Smirnov (KS) test and likelihood ratio test for zero-inflated count data, based on the work of Aldirawi et al. (2019) <doi:10.1109/BHI.2019.8834661>. With the package, user can also find tools to simulate random deviates from zero inflated or hurdle models and obtain maximum likelihood estimate of unknown parameters in these models.

This package performs Invariant Coordinate Selection (ICS) (Tyler, Critchley, Duembgen and Oja (2009) <doi:10.1111/j.1467-9868.2009.00706.x>) and especially ICS for multivariate outlier detection with application to quality control (Archimbaud, Nordhausen, Ruiz-Gazen (2018) <doi:10.1016/j.csda.2018.06.011>) using a shiny app.

This package provides convenient access to the German modification of the International Classification of Diagnoses, 10th revision (ICD-10-GM). It provides functionality to aid in the identification, specification and historisation of ICD-10 codes. Its intended use is the analysis of routinely collected data in the context of epidemiology, medical research and health services research. The underlying metadata are released by the German Institute for Medical Documentation and Information <https://www.dimdi.de>, and are redistributed in accordance with their license.

Advanced fuzzy logic based techniques are implemented to compute the similarity among different objects or items. Typically, application areas consist of transforming raw data into the corresponding advanced fuzzy logic representation and determining the similarity between two objects using advanced fuzzy similarity techniques in various fields of research, such as text classification, pattern recognition, software projects, decision-making, medical diagnosis, and market prediction. Functions are designed to compute the membership, non-membership, hesitant-membership, indeterminacy-membership, and refusal-membership for the input matrices. Furthermore, it also includes a large number of advanced fuzzy logic based similarity measure functions to compute the Intuitionistic fuzzy similarity (IFS), Pythagorean fuzzy similarity (PFS), and Spherical fuzzy similarity (SFS) between two objects or items based on their fuzzy relationships. It also includes working examples for each function with sample data sets.

Paquete creado con el fin de facilitar el cálculo y distribución del à ndice Socio Material Territorial (ISMT), elaborado por el Observatorio de Ciudades UC. La metodologà a completa está disponible en "ISMT" (<https://ideocuc-ocuc.hub.arcgis.com/datasets/6ed956450cfc4293b7d90df3ce3474e4/about>) [Observatorio de Ciudades UC (2019)]. || Package created to facilitate the calculation and distribution of the Socio-Material Territorial Index by Observatorio de Ciudades UC. The full methodology is available at "ISMT" (<https://ideocuc-ocuc.hub.arcgis.com/datasets/6ed956450cfc4293b7d90df3ce3474e4/about>) [Observatorio de Ciudades UC (2019)].

This package provides a collection of Item Response Theory (IRT) and Computerized Adaptive Testing (CAT) functions that are used in psychometrics.

Computes and tests individual (species, phylogenetic and functional) diversity-area relationships, i.e., how species-, phylogenetic- and functional-diversity varies with spatial scale around the individuals of some species in a community. See applications of these methods in Wiegand et al. (2007) <doi:10.1073/pnas.0705621104> or Chacon-Labella et al. (2016) <doi:10.1007/s00442-016-3547-z>.

This package provides implementation of various correlation coefficients of common use in Information Retrieval. In particular, it includes Kendall (1970, isbn:0852641990) tau coefficient as well as tau_a and tau_b for the treatment of ties. It also includes Yilmaz et al. (2008) <doi:10.1145/1390334.1390435> tauAP correlation coefficient, and versions tauAP_a and tauAP_b developed by Urbano and Marrero (2017) <doi:10.1145/3121050.3121106> to cope with ties.

An implementation of the "FAST-9" corner detection algorithm explained in the paper FASTER and better: A machine learning approach to corner detection by Rosten E., Porter R. and Drummond T. (2008), available at <doi:10.48550/arXiv.0810.2434>. The package allows to detect corners in digital images.

Implementation of Tyler, Critchley, Duembgen and Oja's (JRSS B, 2009, <doi:10.1111/j.1467-9868.2009.00706.x>) and Oja, Sirkia and Eriksson's (AJS, 2006, <https://www.ajs.or.at/index.php/ajs/article/view/vol35,%20no2%263%20-%207>) method of two different scatter matrices to obtain an invariant coordinate system or independent components, depending on the underlying assumptions.

Pre-processing and basic analytical tasks for working with Eurostat's symmetric inputâ output tables, and basic inputâ output economics calculations. Part of rOpenGov <https://ropengov.github.io/> for open source open government initiatives.

This package provides a multivariate Gaussian mixture model framework to integrate multiple types of genomic data and allow modeling of inter-data-type correlations for association analysis. IMIX can be implemented to test whether a disease is associated with genes in multiple genomic data types, such as DNA methylation, copy number variation, gene expression, etc. It can also study the integration of multiple pathways. IMIX uses the summary statistics of association test outputs and conduct integration analysis for two or three types of genomics data. IMIX features statistically-principled model selection, global FDR control and computational efficiency. Details are described in Ziqiao Wang and Peng Wei (2020) <doi:10.1093/bioinformatics/btaa1001>.

Interactive plots for R.