This package provides a fragmentation spectra detection pipeline for high-throughput LC/HRMS data processing using peaklists generated by the IDSL.IPA workflow <doi:10.1021/acs.jproteome.2c00120>. The IDSL.CSA package can deconvolute fragmentation spectra from Composite Spectra Analysis (CSA), Data Dependent Acquisition (DDA) analysis, and various Data-Independent Acquisition (DIA) methods such as MS^E, All-Ion Fragmentation (AIF) and SWATH-MS analysis. The IDSL.CSA package was introduced in <doi:10.1021/acs.analchem.3c00376>.

This package provides a set of tools for writing documents according to Geneva Graduate Institute conventions and regulations. The most common use is for writing and compiling theses or thesis chapters, as drafts or for examination with correct preamble formatting. However, the package also offers users to create HTML presentation slides with xaringan', complete problem sets, format posters, and, for course instructors, prepare a syllabus. The package includes additional functions for institutional color palettes, an institutional ggplot theme, a function for counting manuscript words, and a bibliographical analysis toolkit.

This package provides API access to the <http://imdbapi.net> which maintains metadata about movies, games and television shows through a public API.

It provides a general framework to analyse dependence between point processes in time. It includes parametric and non-parametric tests to study independence, and functions for generating and analysing different types of dependence.

This package provides a set of functions for the modeling of data derived from the Minidisc Infiltrometer device. It calculates cumulative infiltration and square root of time. Also, it calculates the A parameter based on soil physical properties.

Implementation of Isolation kernel (Qin et al. (2019) <doi:10.1609/aaai.v33i01.33014755>).

As a sequel to iNEXT', the iNEXT.beta3D package provides functions to compute standardized taxonomic, phylogenetic, and functional diversity (3D) estimates with a common sample size (for alpha and gamma diversity) or sample coverage (for alpha, beta, gamma diversity as well as dissimilarity or turnover indices). Hill numbers and their generalizations are used to quantify 3D and to make multiplicative decomposition (gamma = alpha x beta). The package also features size- and coverage-based rarefaction and extrapolation sampling curves to facilitate rigorous comparison of beta diversity across datasets. See Chao et al. (2023) <doi:10.1002/ecm.1588> for more details.

This package implements the Information Matrix test for regression models following Cameron, A. C., & Trivedi, P. K. (1990) <https://cameron.econ.ucdavis.edu/research/imtest_impliedalternatives_ucdwp372.pdf> Decomposes the test into components for heteroscedasticity, skewness, and kurtosis to diagnose specific forms of misspecification. Provides both overall and component-wise statistics for model assessment.

Identify Cancer Dysfunctional Sub-pathway by integrating gene expression, DNA methylation and copy number variation, and pathway topological information. 1)We firstly calculate the gene risk scores by integrating three kinds of data: DNA methylation, copy number variation, and gene expression. 2)Secondly, we perform a greedy search algorithm to identify the key dysfunctional sub-pathways within the pathways for which the discriminative scores were locally maximal. 3)Finally, the permutation test was used to calculate statistical significance level for these key dysfunctional sub-pathways.

Functionality required to efficiently use R with IBM(R) Db2(R) Warehouse offerings (formerly IBM dashDB(R)) and IBM Db2 for z/OS(R) in conjunction with IBM Db2 Analytics Accelerator for z/OS. Many basic and complex R operations are pushed down into the database, which removes the main memory boundary of R and allows to make full use of parallel processing in the underlying database. For executing R-functions in a multi-node environment in parallel the idaTApply() function requires the SparkR package (<https://spark.apache.org/docs/latest/sparkr.html>). The optional ggplot2 package is needed for the plot.idaLm() function only.

Easily implement the checking of WHOIS information for a particular domain. IP2WHOIS supports the query for 1113 Top-level Domains(TLDs) and 634 Country Code Top-level Domains(ccTLDs). To get started with a free API key, you may sign up at here <https://www.ip2whois.com/register>.

Implementation of some Individual Based Models (IBMs, sensu Grimm and Railsback 2005) and methods to create new ones, particularly for population dynamics models (reproduction, mortality and movement). The basic operations for the simulations are implemented in Rcpp for speed.

Empirical Bayes variable selection via ICM/M algorithm for normal, binary logistic, and Cox's regression. The basic problem is to fit high-dimensional regression which sparse coefficients. This package allows incorporating the Ising prior to capture structure of predictors in the modeling process. More information can be found in the papers listed in the URL below.

Develops a General Equilibrium (GE) Model, which estimates key variables such as wages, the number of residents and workers, the prices of the floor space, and its distribution between commercial and residential use, as in Ahlfeldt et al., (2015) <doi:10.3982/ECTA10876>. By doing so, the model allows understanding the economic influence of different urban policies.

This package provides a pair of functions for getting and setting the IEEE rounding mode for floating point computations.

This package performs exploratory data analysis and variable screening for binary classification models using weight-of-evidence (WOE) and information value (IV). In order to make the package as efficient as possible, aggregations are done in data.table and creation of WOE vectors can be distributed across multiple cores. The package also supports exploration for uplift models (NWOE and NIV).

Integrated B-spline function.

This package performs hypothesis testing using the interval estimates (e.g., confidence intervals). The non-overlapping interval estimates indicates the statistical significance. References to these procedures can be found at Noguchi and Marmolejo-Ramos (2016) <doi:10.1080/00031305.2016.1200487>, Bonett and Seier (2003) <doi:10.1198/0003130032323>, and Lemm (2006) <doi:10.1300/J082v51n02_05>.

This package provides functions to analyse missing value mechanisms and to impute data sets in the context of bottom-up MS-based proteomics.

This package implements an algorithm for fitting a generative model with an intractable likelihood using only box constraints on the parameters. The implemented algorithm consists of two phases. The first phase (global search) aims to identify the region containing the best solution, while the second phase (local search) refines this solution using a trust-region version of the Fisher scoring method to solve a quasi-likelihood equation. See Guido Masarotto (2025) <doi:10.48550/arXiv.2511.08180> for the details of the algorithm and supporting results.

This package implements Interpretable Boosted Linear Models (IBLMs). These combine a conventional generalized linear model (GLM) with a machine learning component, such as XGBoost. The package also provides tools within for explaining and analyzing these models. For more details see Gawlowski and Wang (2025) <https://ifoa-adswp.github.io/IBLM/reference/figures/iblm_paper.pdf>.

After testing for biased treatment assignment in an observational study using an unaffected outcome, the sensitivity analysis is constrained to be compatible with that test. The package uses the optimization software gurobi obtainable from <https://www.gurobi.com/>, together with its associated R package, also called gurobi; see: <https://www.gurobi.com/documentation/7.0/refman/installing_the_r_package.html>. The method is a substantial computational and practical enhancement of a concept introduced in Rosenbaum (1992) Detecting bias with confidence in observational studies Biometrika, 79(2), 367-374 <doi:10.1093/biomet/79.2.367>.

Display a 2D-matrix data as a interactive zoomable gray-scale image viewer, providing tools for manual data inspection. The viewer window shows cursor guiding lines and a corresponding data slices for both axes at the current cursor position. A tool-bar allows adjusting image display brightness/contrast through WebGL filters and performing basic high-pass/low-pass filtering.

Data sets, functions and scripts with examples to implement autoregressive models for irregularly observed time series. The models available in this package are the irregular autoregressive model (Eyheramendy et al.(2018) <doi:10.1093/mnras/sty2487>), the complex irregular autoregressive model (Elorrieta et al.(2019) <doi:10.1051/0004-6361/201935560>) and the bivariate irregular autoregressive model (Elorrieta et al.(2021) <doi:10.1093/mnras/stab1216>).