Helper functions to build SQL statements for dbGetQuery or dbSendQuery under program control. They are intended to increase speed of coding and to reduce coding errors. Arguments are carefully checked, in particular SQL identifiers such as names of tables or columns. More patterns will be added as required.

Obtain least-squares means for linear, generalized linear, and mixed models. Compute contrasts or linear functions of least-squares means, and comparisons of slopes. Plots and compact letter displays. Least-squares means were proposed in Harvey, W (1960) "Least-squares analysis of data with unequal subclass numbers", Tech Report ARS-20-8, USDA National Agricultural Library, and discussed further in Searle, Speed, and Milliken (1980) "Population marginal means in the linear model: An alternative to least squares means", The American Statistician 34(4), 216-221 <doi:10.1080/00031305.1980.10483031>. NOTE: lsmeans now relies primarily on code in the emmeans package. lsmeans will be archived in the near future.

An implementation of estimating the Latent Unknown Clusters By Integrating Multi-omics Data (LUCID) model (Peng (2019) <doi:10.1093/bioinformatics/btz667>). LUCID conducts integrated clustering using exposures, omics information (and outcome information as an option). This package implements three different integration strategies for multi-omics data analysis within the LUCID framework: LUCID early integration (the original LUCID model), LUCID in parallel (intermediate integration), and LUCID in serial (late integration). Automated model selection for each LUCID model is available to obtain the optimal number of latent clusters, and an integrated imputation approach is implemented to handle sporadic and list-wise missingness in multi-omics data. Lasso-type regularity for exposure and omics features were added. S3 methods for summary and plotting functions were fixed. Fixed minor bugs.

This package provides a graphical user interface with an integrated diagrammer for latent variable models from the lavaan package. It offers two core functions: first, lavaangui() launches a web application that allows users to specify models by drawing path diagrams, fitting them, assessing model fit, and more; second, plot_lavaan() creates interactive path diagrams from models specified in lavaan'. Karch (2024) <doi: 10.1080/10705511.2024.2420678> contains a tutorial.

Various opportunities to evaluate the effects of including one or more control variable(s) in structural equation models onto model-implied variances, covariances, and parameter estimates. The derivation of the methodology employed in this package can be obtained from Blötner (2023) <doi:10.31234/osf.io/dy79z>.

Identification of equilibrium locations in location games (Hotelling (1929) <doi:10.2307/2224214>). In these games, two competing actors place customer-serving units in two locations simultaneously. Customers make the decision to visit the location that is closest to them. The functions in this package include Prim algorithm (Prim (1957) <doi:10.1002/j.1538-7305.1957.tb01515.x>) to find the minimum spanning tree connecting all network vertices, an implementation of Dijkstra algorithm (Dijkstra (1959) <doi:10.1007/BF01386390>) to find the shortest distance and path between any two vertices, a self-developed algorithm using elimination of purely dominated strategies to find the equilibrium, and several plotting functions.

Label-free bottom-up proteomics expression data is often affected by data heterogeneity and missing values. Normalization and missing value imputation are commonly used techniques to address these issues and make the dataset suitable for further downstream analysis. This package provides an optimal combination of normalization and imputation methods for the dataset. The package utilizes three normalization methods and three imputation methods.The statistical evaluation measures named pooled co-efficient of variance, pooled estimate of variance and pooled median absolute deviation are used for selecting the best combination of normalization and imputation method for the given dataset. The user can also visualize the results by using various plots available in this package. The user can also perform the differential expression analysis between two sample groups with the function included in this package. The chosen three normalization methods, three imputation methods and three evaluation measures were chosen for this study based on the research papers published by Välikangas et al. (2016) <doi:10.1093/bib/bbw095>, Jin et al. (2021) <doi:10.1038/s41598-021-81279-4> and Srivastava et al. (2023) <doi:10.2174/1574893618666230223150253>.This work has published by Sakthivel et al. (2025) <doi:10.1021/acs.jproteome.4c00552>.

Data used as examples in the loon package.

Helps to render interlinear glossed linguistic examples in html rmarkdown documents and then semi-automatically compiles the list of glosses at the end of the document. It also provides a database of linguistic glosses.

Density, distribution function, quantile function and random generation for the L-Logistic distribution with parameters m and phi. The parameter m is the median of the distribution.

Palettes generated from limnology based field and laboratory photos. Palettes can be used to generate color values to be used in any functions that calls for a color (i.e. ggplot(), plot(), flextable(), etc.).

Fit relationship-based and customized mixed-effects models with complex variance-covariance structures using the lme4 machinery. The core computational algorithms are implemented using the Eigen C++ library for numerical linear algebra and RcppEigen glue'.

L-systems or Lindenmayer systems are parallel rewriting systems which can be used to simulate biological forms and certain kinds of fractals. Briefly, in an L-system a series of symbols in a string are replaced iteratively according to rules to give a more complex string. Eventually, the symbols are translated into turtle graphics for plotting. Wikipedia has a very good introduction: en.wikipedia.org/wiki/L-system This package provides basic functions for exploring L-systems.

Consider linear regression model Y = Xb + error where the distribution function of errors is unknown, but errors are independent and symmetrically distributed. The package contains a function named LRMDE which takes Y and X as input and returns minimum distance estimator of parameter b in the model.

Nonparametric methods for landmark prediction of long-term survival outcomes, incorporating covariate and short-term event information. The package supports the construction of flexible varying-coefficient models that use discrete covariates, as well as multiple continuous covariates. The goal is to improve prediction accuracy when censored short-term events are available as predictors, using robust nonparametric procedures that do not require correct model specification and avoid restrictive parametric assumptions found in alternative methods. More information on these methods can be found in Parast et al. 2012 <doi:10.1080/01621459.2012.721281>, Parast et al. 2011 <doi:10.1002/bimj.201000150>, and Parast and Cai 2013 <doi:10.1002/sim.5776>. A tutorial for this package is available here: <https://www.laylaparast.com/landpred>.

This package provides a complete framework for frequency analysis is provided by LMoFit'. It has functions related to the determination of sample L-moments as in Hosking, J.R.M. (1990) <doi:10.1111/j.2517-6161.1990.tb01775.x>, the fitting of various distributions as in Zaghloul et al. (2020) <doi:10.1016/j.advwatres.2020.103720> and Hosking, J.R.M. (2019) <https://CRAN.R-project.org/package=lmom>, besides plotting and manipulating L-space diagrams as in Papalexiou, S.M. & Koutsoyiannis, D. (2016) <doi:10.1016/j.advwatres.2016.05.005> for two-shape parametric distributions on the L-moment ratio diagram. Additionally, the quantile, probability density, and cumulative probability functions of various distributions are provided in a user-friendly manner.

The goal of LCMSQA is to make it easy to check the quality of liquid chromatograph/mass spectrometry (LC/MS) experiments using a shiny application. This package provides interactive data visualizations for quality control (QC) samples, including total ion current chromatogram (TIC), base peak chromatogram (BPC), mass spectrum, extracted ion chromatogram (XIC), and feature detection results from internal standards or known metabolites.

An HTML widget that randomly tours 2D projections of numerical data. A random walk through projections of the data is shown. The user can manipulate the plot to use specified axes, or turn on Guided Tour mode to find an informative projection of the data. Groups within the data can be hidden or shown, as can particular axes. Points can be brushed, and the selection can be linked to other widgets using crosstalk. The underlying method to produce the random walk and projection pursuit uses Langevin dynamics. The widget can be used from within R, or included in a self-contained R Markdown or Quarto document or presentation, or used in a Shiny app.

Set of tools for mapping of categorical response variables based on principal component analysis (pca) and multidimensional unfolding (mdu).

Code generator for robust dependency-free Shiny applications in the form of packages. It includes numerous convenience functions to create modules, include utility functions to create common Bootstrap elements, setup a project from the ground-up, and much more.

Fast implementations to compute the genetic covariance matrix, the Jaccard similarity matrix, the s-matrix (the weighted Jaccard similarity matrix), and the (classic or robust) genomic relationship matrix of a (dense or sparse) input matrix (see Hahn, Lutz, Hecker, Prokopenko, Cho, Silverman, Weiss, and Lange (2020) <doi:10.1002/gepi.22356>). Full support for sparse matrices from the R-package Matrix'. Additionally, an implementation of the power method (von Mises iteration) to compute the largest eigenvector of a matrix is included, a function to perform an automated full run of global and local correlations in population stratification data, a function to compute sliding windows, and a function to invert minor alleles and to select those variants/loci exceeding a minimal cutoff value. New functionality in locStra allows one to extract the k leading eigenvectors of the genetic covariance matrix, Jaccard similarity matrix, s-matrix, and genomic relationship matrix via fast PCA without actually computing the similarity matrices. The fast PCA to compute the k leading eigenvectors can now also be run directly from bed'+'bim'+'fam files.

LineUp is an interactive technique designed to create, visualize and explore rankings of items based on a set of heterogeneous attributes. This is a htmlwidget wrapper around the JavaScript library LineUp.js'. It is designed to be used in R Shiny apps and R Markddown files. Due to an outdated webkit version of RStudio it won't work in the integrated viewer.

An efficient procedure for feature selection for generalized linear models with L0 penalty, including linear, logistic, Poisson, gamma, inverse Gaussian regression. Adaptive ridge algorithms are used to fit the models.

This package provides a bunch of algorithms based on linear programming for estimating, under the homogeneity hypothesis, RxC ecological contingency tables (or vote transition matrices) using mainly aggregate data (from voting units). References: Pavà a and Romero (2024) <doi:10.1177/00491241221092725>. Pavà a and Romero (2024) <doi:10.1093/jrsssa/qnae013>. Pavà a (2023) <doi:10.1007/s43545-023-00658-y>. Pavà a (2024) <doi:10.1080/0022250X.2024.2423943>. Pavà a (2024) <doi:10.1177/07591063241277064>. Pavà a and Penadés (2024). A bottom-up approach for ecological inference. Romero, Pavà a, Martà n and Romero (2020) <doi:10.1080/02664763.2020.1804842>. Acknowledgements: The authors wish to thank Consellerà a de Educación, Cultura, Universidades y Empleo, Generalitat Valenciana (grants AICO/2021/257, CIAICO/2023/031) and MICIU/AEI/10.13039/501100011033/FEDER, UE (grant PID2021-128228NB-I00) for supporting this research.