The goal of MRMCbinary is to compare the performance of diagnostic tests (i.e., sensitivity and specificity) for binary outcomes in multi-reader multi-case (MRMC) studies. It is based on conditional logistic regression and Cochranâ s Q test (or McNemarâ s test when the number of modalities is equal to 2).

Offers automation tools to parallelize Mplus operations when using R for data generation. It facilitates streamlined integration between Mplus and R', allowing users to run and manage multiple Mplus models simultaneously and efficiently in R'.

Regression methods to quantify the relation between two measurement methods are provided by this package. In particular it addresses regression problems with errors in both variables and without repeated measurements. It implements the Clinical Laboratory Standard International (CLSI) recommendations (see J. A. Budd et al. (2018, <https://clsi.org/standards/products/method-evaluation/documents/ep09/>) for analytical method comparison and bias estimation using patient samples. Furthermore, algorithms for Theil-Sen and equivariant Passing-Bablok estimators are implemented, see F. Dufey (2020, <doi:10.1515/ijb-2019-0157>) and J. Raymaekers and F. Dufey (2022, <arXiv:2202:08060>). Further the robust M-Deming and MM-Deming (experimental) are available, see G. Pioda (2021, <arXiv:2105:04628>). A comprehensive overview over the implemented methods and references can be found in the manual pages mcrPioda-package and mcreg'.

Provide a sample size calculator for micro-randomized trials (MRTs) based on methodology developed in Sample Size Calculations for Micro-randomized Trials in mHealth by Liao et al. (2016) <DOI:10.1002/sim.6847>.

Calculates mean cumulative count (MCC) to estimate the expected cumulative number of recurrent events per person over time in the presence of competing risks and censoring. Implements both the Dong-Yasui equation method and sum of cumulative incidence method described in Dong, et al. (2015) <doi:10.1093/aje/kwu289>. Supports inverse probability weighting for causal inference as outlined in Gaber, et al. (2023) <doi:10.1093/aje/kwad031>. Provides S3 methods for printing, summarizing, plotting, and extracting results. Handles grouped analyses and integrates with ggplot2 <https://ggplot2.tidyverse.org/> for visualization.

This package provides functions for multivariate and propensity score matching and for finding optimal balance based on a genetic search algorithm. A variety of univariate and multivariate metrics to determine if balance has been obtained are also provided. For details, see the paper by Jasjeet Sekhon (2007, <doi:10.18637/jss.v042.i07>).

This package performs the execution of the main procedures of multiple comparisons in the literature, Scott-Knott (1974) <http://www.jstor.org/stable/2529204>, Batista (2016) <http://repositorio.ufla.br/jspui/handle/1/11466>, including graphic representations and export to different extensions of its results. An additional part of the package is the presence of the performance evaluation of the tests (Type I error per experiment and the power). This will assist the user in making the decision for the chosen test.

Micro simulation model to reproduce natural history of cervical cancer and cost-effectiveness evaluation of prevention strategies. See Georgalis L, de Sanjose S, Esnaola M, Bosch F X, Diaz M (2016) <doi:10.1097/CEJ.0000000000000202> for more details.

Fit the most popular human mortality laws', and construct full and abridge life tables given various input indices. A mortality law is a parametric function that describes the dying-out process of individuals in a population during a significant portion of their life spans. For a comprehensive review of the most important mortality laws see Tabeau (2001) <doi:10.1007/0-306-47562-6_1>. Practical functions for downloading data from various human mortality databases are provided as well.

High-performance MongoDB client based on mongo-c-driver and jsonlite'. Includes support for aggregation, indexing, map-reduce, streaming, encryption, enterprise authentication, and GridFS. The online user manual provides an overview of the available methods in the package: <https://jeroen.github.io/mongolite/>.

This package provides methods for performing genetic risk prediction from genotype data. You can use it to perform risk prediction for individuals, or for families with missing data.

Normally building a GODB is fairly complicated, involving downloading multiple database files and using these to build e.g. a mySQL database. Accessing this database is also complicated, involving an intimate knowledge of the database in order to construct reliable queries. Here we have a more modest goal, generating GOGOA3, which is a stripped down version of the GODB that was originally restricted to human genes as designated by the HUGO Gene Nomenclature Committee (HGNC) (see <https://geneontology.org/>). I have now added about two dozen additional species, namely all species represented on the Gene Ontology download page <https://current.geneontology.org/products/pages/downloads.html>. This covers most of the model organisms that are commonly used in bio-medical and basic research (assuming that anyone still has a grant to do such research). This can be built in a matter of seconds from 2 easily downloaded files (see <https://current.geneontology.org/products/pages/downloads.html> and <https://geneontology.org/docs/download-ontology/>), and it can be queried by e.g. w<-which(GOGOA3[,"HGNC"] %in% hgncList) where GOGOA3 is a matrix representing the minimalist GODB and hgncList is a list of gene identifiers. This database will be used in my upcoming package GoMiner which is based on my previous publication (see Zeeberg, B.R., Feng, W., Wang, G. et al. (2003)<doi:10.1186/gb-2003-4-4-r28>). Relevant .RData files are available from GitHub (<https://github.com/barryzee/GO/tree/main/databases>).

You can use the set of wrappers for analytical schemata to reduce the effort in writing machine-readable data. The set of all-in-one wrappers will cover widely used functions from data analysis packages.

This package provides R6 objects to perform parallelized hyperparameter optimization and cross-validation. Hyperparameter optimization can be performed with Bayesian optimization (via rBayesianOptimization <https://cran.r-project.org/package=rBayesianOptimization>) and grid search. The optimized hyperparameters can be validated using k-fold cross-validation. Alternatively, hyperparameter optimization and validation can be performed with nested cross-validation. While mlexperiments focuses on core wrappers for machine learning experiments, additional learner algorithms can be supplemented by inheriting from the provided learner base class.

Estimation and inference for multiple kink quantile regression for longitudinal data and the i.i.d data. A bootstrap restarting iterative segmented quantile algorithm is proposed to estimate the multiple kink quantile regression model conditional on a given number of change points. The number of kinks is also allowed to be unknown. In such case, the backward elimination algorithm and the bootstrap restarting iterative segmented quantile algorithm are combined to select the number of change points based on a quantile BIC. For longitudinal data, we also develop the GEE estimator to incorporate the within-subject correlations. A score-type based test statistic is also developed for testing the existence of kink effect. The package is based on the paper, ``Wei Zhong, Chuang Wan and Wenyang Zhang (2022). Estimation and inference for multikink quantile regression, JBES and ``Chuang Wan, Wei Zhong, Wenyang Zhang and Changliang Zou (2022). Multi-kink quantile regression for longitudinal data with application to progesterone data analysis, Biometrics".

Automatic marking of R assignments for students and teachers based on testthat test suites.

This package provides a collection of functions for the analysis of archaeological mortality data (on the topic see e.g. Chamberlain 2006 <https://books.google.de/books?id=nG5FoO_becAC&lpg=PA27&ots=LG0b_xrx6O&dq=life%20table%20archaeology&pg=PA27#v=onepage&q&f=false>). It takes demographic data in different formats and displays the result in a standard life table as well as plots the relevant indices (percentage of deaths, survivorship, probability of death, life expectancy, percentage of population). It also checks for possible biases in the age structure and applies corrections to life tables.

This package provides an extension of the shadow-test approach to computerized adaptive testing (CAT) implemented in the TestDesign package for the assessment framework involving multiple tests administered periodically throughout the year. This framework is referred to as the Multiple Administrations Adaptive Testing (MAAT) and supports multiple item pools vertically scaled and multiple phases (stages) of CAT within each test. Between phases and tests, transitioning from one item pool (and associated constraints) to another is allowed as deemed necessary to enhance the quality of measurement.

This package implements the Multi-view Aggregated Two-Sample (MATES) test, a powerful nonparametric method for testing equality of two multivariate distributions. The method constructs multiple graph-based statistics from various perspectives (views) including different distance metrics, graph types (nearest neighbor graphs, minimum spanning trees, and robust nearest neighbor graphs), and weighting schemes. These statistics are then aggregated through a quadratic form to achieve improved statistical power. The package provides both asymptotic closed-form inference and permutation-based testing procedures. For methodological details, see Cai and others (2026+) <doi:10.48550/arXiv.2412.16684>.

We introduce a generalized factor model designed to jointly analyze high-dimensional multi-modality data from multiple studies by extracting study-shared and specified factors. Our factor models account for heterogeneous noises and overdispersion among modality variables with augmented covariates. We propose an efficient and speedy variational estimation procedure for estimating model parameters, along with a novel criterion for selecting the optimal number of factors. More details can be referred to Liu et al. (2025) <doi:10.48550/arXiv.2507.09889>.

Simulates Multidimensional Adaptive Testing using the multidimensional three-parameter logistic model as described in Segall (1996) <doi:10.1007/BF02294343>, van der Linden (1999) <doi:10.3102/10769986024004398>, Reckase (2009) <doi:10.1007/978-0-387-89976-3>, and Mulder & van der Linden (2009) <doi:10.1007/s11336-008-9097-5>.

Analyses the stability and structural behaviour of export and import patterns across multiple countries using a Markov chain modelling framework. Constructs transition probability matrices to quantify changes in trade shares between successive periods, thereby capturing persistence, structural shifts, and inter-country interdependence in trade performance. By iteratively generating expected trade distributions over time, the approach facilitates assessment of stability, long-run equilibrium tendencies, and comparative dynamics in longitudinal trade data, providing a rigorous tool for empirical analysis of exportâ import behaviour. Methodological foundations follow standard Markov chain theory as described in Gagniuc (2017) <Doi:10.1002/9781119387596>.

This package provides a set of evolutionary algorithms to solve many-objective optimization. Hybridization between the algorithms are also facilitated. Available algorithms are: SMS-EMOA <doi:10.1016/j.ejor.2006.08.008> NSGA-III <doi:10.1109/TEVC.2013.2281535> MO-CMA-ES <doi:10.1145/1830483.1830573> The following many-objective benchmark problems are also provided: DTLZ1'-'DTLZ4 from Deb, et al. (2001) <doi:10.1007/1-84628-137-7_6> and WFG4'-'WFG9 from Huband, et al. (2005) <doi:10.1109/TEVC.2005.861417>.

Tokenize text into morphemes. The morphemepiece algorithm uses a lookup table to determine the morpheme breakdown of words, and falls back on a modified wordpiece tokenization algorithm for words not found in the lookup table.