This is an EM algorithm based method for imputation of missing values in multivariate normal time series. The imputation algorithm accounts for both spatial and temporal correlation structures. Temporal patterns can be modeled using an ARIMA(p,d,q), optionally with seasonal components, a non-parametric cubic spline or generalized additive models with exogenous covariates. This algorithm is specially tailored for climate data with missing measurements from several monitors along a given region.

Implementation of Warnes & Raftery's MCGibbsit run-length and convergence diagnostic for a set of (not-necessarily independent) Markov Chain Monte Carlo (MCMC) samplers. It combines the quantile estimate error-bounding approach of the Raftery and Lewis MCMC run length diagnostic `gibbsit` with the between verses within chain approach of the Gelman and Rubin MCMC convergence diagnostic.

Makes it possible to create an internally consistent repository consisting of selected packages from CRAN-like repositories. The user specifies a set of desired packages, and miniCRAN recursively reads the dependency tree for these packages, then downloads only this subset. The user can then install packages from this repository directly, rather than from CRAN. This is useful in production settings, e.g. server behind a firewall, or remote locations with slow (or zero) Internet access.

Fifteen tools for bioinformatics processing and analysis of major histocompatibility complex (MHC) data. The functions are tailored for amplicon data sets that have been filtered using the dada2 method (for more information on dada2, visit <https://benjjneb.github.io/dada2/> ), but even other types of data sets can be analyzed. The ReplMatch() function matches replicates in data sets in order to evaluate genotyping success. The GetReplTable() and GetReplStats() functions perform such an evaluation. The CreateFas() function creates a fasta file with all the sequences in the data set. The CreateSamplesFas() function creates individual fasta files for each sample in the data set. The DistCalc() function calculates Grantham, Sandberg, or p-distances from pairwise comparisons of all sequences in a data set, and mean distances of all pairwise comparisons within each sample in a data set. The function additionally outputs five tables with physico-chemical z-descriptor values (based on Sandberg et al. 1998) for each amino acid position in all sequences in the data set. These tables may be useful for further downstream analyses, such as estimation of MHC supertypes. The BootKmeans() function is a wrapper for the kmeans() function of the stats package, which allows for bootstrapping. Bootstrapping k-estimates may be desirable in data sets, where e.g. BIC- vs. k-values do not produce clear inflection points ("elbows"). BootKmeans() performs multiple runs of kmeans() and estimates optimal k-values based on a user-defined threshold of BIC reduction. The method is an automated and bootstrapped version of visually inspecting elbow plots of BIC- vs. k-values. The ClusterMatch() function is a tool for evaluating whether different k-means() clustering models identify similar clusters, and summarize bootstrap model stats as means for different estimated values of k. It is designed to take files produced by the BootKmeans() function as input, but other data can be analyzed if the descriptions of the required data formats are observed carefully. The PapaDiv() function compares parent pairs in the data set and calculate their joint MHC diversity, taking into account sequence variants that occur in both parents. The HpltFind() function infers putative haplotypes from families in the data set. The GetHpltTable() and GetHpltStats() functions evaluate the accuracy of the haplotype inference. The CreateHpltOccTable() function creates a binary (logical) haplotype-sequence occurrence matrix from the output of HpltFind(), for easy overview of which sequences are present in which haplotypes. The HpltMatch() function compares haplotypes to help identify overlapping and potentially identical types. The NestTablesXL() function translates the output from HpltFind() to an Excel workbook, that provides a convenient overview for evaluation and curating of the inferred putative haplotypes.

Inference of a multi-states birth-death model from a phylogeny, comprising a number of states N, birth and death rates for each state and on which edges each state appears. Inference is done using a hybrid approach: states are progressively added in a greedy approach. For a fixed number of states N the best model is selected via maximum likelihood. Reference: J. Barido-Sottani, T. G. Vaughan and T. Stadler (2018) <doi:10.1098/rsif.2018.0512>.

Analyses species distribution models and evaluates their performance. It includes functions for variation partitioning, extracting variable importance, computing several metrics of model discrimination and calibration performance, optimizing prediction thresholds based on a number of criteria, performing multivariate environmental similarity surface (MESS) analysis, and displaying various analytical plots. Initially described in Barbosa et al. (2013) <doi:10.1111/ddi.12100>.

This package implements a computational framework to predict microbial community-based metabolic profiles with O2PLS model. It provides procedures of model training and prediction. Paired microbiome and metabolome data are needed for modeling, and the trained model can be applied to predict metabolites of analogous environments using new microbial feature abundances.

Modeling microstructures of human tooth dentin and horizontal serial-sectioning of the dentin. Corresponding age range of dentin serial sections, that is used in stable isotope analyses, can be calculated by using this package.

Routines for assessing multivariate normality. Implements three Wald's type chi-squared tests; non-parametric Anderson-Darling and Cramer-von Mises tests; Doornik-Hansen test, Royston test and Henze-Zirkler test.

Characterization of a mid-summer drought (MSD) with precipitation based statistics. The MSD is a phenomenon of decreased rainfall during a typical rainy season. It is a feature of rainfall in much of Central America and is also found in other locations, typically those with a Mediterranean climate. Details on the metrics are in Maurer et al. (2022) <doi:10.5194/hess-26-1425-2022>.

Extract, transform and load MITRE standards. This package gives you an approach to cybersecurity data sets. All data sets are build on runtime downloading raw data from MITRE public services. MITRE <https://www.mitre.org/> is a government-funded research organization based in Bedford and McLean. Current version includes most used standards as data frames. It also provide a list of nodes and edges with all relationships.

Computationally efficient functions to provide direct likelihood-based inference for partially-observed multivariate birth-death processes. Such processes range from a simple Yule model to the complex susceptible-infectious-removed model in disease dynamics. Efficient likelihood evaluation facilitates maximum likelihood estimation and Bayesian inference.

This package provides a way to estimate and test marginal mediation effects for zero-inflated compositional mediators. Estimates of Natural Indirect Effect (NIE), Natural Direct Effect (NDE) of each taxon, as well as their standard errors and confident intervals, were provided as outputs. Zeros will not be imputed during analysis. See Wu et al. (2022) <doi:10.3390/genes13061049>.

Computing package for Multidimensional Poverty Index (MPI) using Alkire-Foster method. Given N individuals, each person has D indicators of deprivation, the package compute MPI value to represent the degree of poverty in a population. The inputs are 1) an N by D matrix, which has the element (i,j) represents whether an individual i is deprived in an indicator j (1 is deprived and 0 is not deprived), and 2) the deprivation threshold. The main output is the MPI value, which has the range between zero and one. MPI value is approaching one if almost all people are deprived in all indicators, and it is approaching zero if almost no people are deprived in any indicator. Please see Alkire S., Chatterjee, M., Conconi, A., Seth, S. and Ana Vaz (2014) <doi:10.35648/20.500.12413/11781/ii039> for The Alkire-Foster methodology.

This package provides a framework to perform soft clustering using simplex-structured matrix factorisation (SSMF). The package contains a set of functions for determining the optimal number of prototypes, the optimal algorithmic parameters, the estimation confidence intervals and the diversity of clusters. Abdolali, Maryam & Gillis, Nicolas (2020) <doi:10.1137/20M1354982>.

Prediction of behaviour from movement characteristics using observation and random forest for the analyses of movement data in ecology. From movement information (speed, bearing...) the model predicts the observed behaviour (movement, foraging...) using random forest. The model can then extrapolate behavioural information to movement data without direct observation of behaviours. The specificity of this method relies on the derivation of multiple predictor variables from the movement data over a range of temporal windows. This procedure allows to capture as much information as possible on the changes and variations of movement and ensures the use of the random forest algorithm to its best capacity. The method is very generic, applicable to any set of data providing movement data together with observation of behaviour.

Data-driven approach for Exploratory Factor Analysis (EFA) that uses Model Implied Instrumental Variables (MIIVs). The method starts with a one factor model and arrives at a suggested model with enhanced interpretability that allows cross-loadings and correlated errors.

This package implements two versions of the algorithm namely: stochastic and batch. The package determines also the best number of clusters and offers to the user the best clustering scheme from different results.

This package implements the generalization of the Shapiro-Wilk test for multivariate normality proposed by Villasenor-Alva and Gonzalez-Estrada (2009).

Implementation of a framework for cluster analysis with selection of the final number of clusters and an optional variable selection procedure. The package is designed to integrate the results of multiple imputed datasets while accounting for the uncertainty that the imputations introduce in the final results. In addition, the package can also be used for a cluster analysis of the complete cases of a single dataset. The package also includes specific methods to summarize and plot the results. The methods are described in Basagana et al. (2013) <doi:10.1093/aje/kws289>.

This package provides a comprehensive range of facilities to perform umbrella reviews with stratification of the evidence in R. The package accomplishes this aim by building on three core functions that: (i) automatically perform all required calculations in an umbrella review (including but not limited to meta-analyses), (ii) stratify evidence according to various classification criteria, and (iii) generate a visual representation of the results. Note that if you are not familiar with R, the core features of this package are available from a web browser (<https://www.metaumbrella.org/>).

This package provides a collection of functions for conducting meta-analysis using a structural equation modeling (SEM) approach via the OpenMx and lavaan packages. It also implements various procedures to perform meta-analytic structural equation modeling on the correlation and covariance matrices, see Cheung (2015) <doi:10.3389/fpsyg.2014.01521>.

This package provides a lightweight package designed to facilitate statistical simulations through functional programming. It centralizes the simulation process into a single higher-order function, enhancing manageability and usability without adding overhead from external dependencies. The package includes ready-to-use functions for common simulation targets. A detailed example can be found on <https://github.com/ielbadisy/mcstatsim>.

Use standard genomics file format (BED) and a table of orthologs to illustrate synteny conservation at the genome-wide scale. Significantly conserved linkage groups are identified as described in Simakov et al. (2020) <doi:10.1038/s41559-020-1156-z> and displayed on an Oxford Grid (Edwards (1991) <doi:10.1111/j.1469-1809.1991.tb00394.x>) or a chord diagram as in Simakov et al. (2022) <doi:10.1126/sciadv.abi5884>. The package provides a function that uses a network-based greedy algorithm to find communities (Clauset et al. (2004) <doi:10.1103/PhysRevE.70.066111>) and so automatically order the chromosomes on the plot to improve interpretability.