This package performs the trimmed k-means clustering algorithm with lower memory use. It also provides a number of utility functions such as BIC calculations.

This package implements the multivariate classification methods of Alexander Alexandrovich Lyubishchev (1890-1972), as described in his 1943 manuscript Programma obshchey sistematiki Lyubishchev (1943) <https://www.zin.ru/animalia/coleoptera/rus/lyubis05.htm> and published in Lubischew (1962) <https://www.jstor.org/stable/2527894>. Provides divergence_coefficient() for measuring separation between groups on continuous features, scatter_ellipse() for fitting covariance ellipses per class, transgression() for detecting ellipse overlap, and classify() for Bayesian posterior classification. These methods predate and are more general than the binary-character similarity coefficients of Sokal and Sneath (1963) that appear in other R packages.

Assess the proportion of treatment effect explained by a longitudinal surrogate marker as described in Agniel D and Parast L (2021) <doi:10.1111/biom.13310>; and estimate the treatment effect on a longitudinal surrogate marker as described in Wang et al. (2025) <doi:10.1093/biomtc/ujaf104>. A tutorial for this package can be found at <https://www.laylaparast.com/longsurr>.

This package implements Expectation/Conditional Maximization Either (ECME), rapidly converging algorithms, and Bayesian inference for linear mixed models following Schafer (1998), "Some Improved Procedures for Linear Mixed Models", Department of Statistics, The Pennsylvania State University.

Convert Leaf Area Index (LAI) from the Normalized Difference Vegetation Index (NDVI) using available equations from literature. Detailed description of conversion equations in Bajocco et al. 2022 <doi:10.3390/rs14153554>.

Calculates cost surfaces based on slope to be used when modelling pathways and movement potential within a landscape (Lewis, 2021) <doi:10.1007/s10816-021-09522-w>.

The leaflet JavaScript library provides many plugins some of which are available in the core leaflet package, but there are many more. It is not possible to support them all in the core leaflet package. This package serves as an add-on to the leaflet package by providing extra functionality via leaflet plugins.

Simplify the loading matrix in factor models using the l1 criterion as proposed in Freyaldenhoven (2025) <doi:10.21799/frbp.wp.2020.25>. Given a data matrix, find the rotation of the loading matrix with the smallest l1-norm and/or test for the presence of local factors with main function local_factors().

This package provides histograms, boxplots and dotplots as alternatives to scatterplots of data when plotting fitted logistic regressions.

Local Polynomial Regression with Ridging.

This package creates a consensus genetic map by merging linkage maps from different populations. The software uses linear programming (LP) to efficiently minimize the mean absolute error between the consensus map and the linkage maps. This minimization is performed subject to linear inequality constraints that ensure the ordering of the markers in the linkage maps is preserved. When marker order is inconsistent between linkage maps, a minimum set of ordinal constraints is deleted to resolve the conflicts.

Large language model agents as governed research instruments, built on LLMR'. The package supports designed conversations and factorial experiments with declared tools and budgets. Each run produces an inspectable record that can be archived and checked.

This package provides a method for detecting multiple change points in high-dimensional time series, targeting dense or spatially clustered signals. See Li et al. (2023) "L2 Inference for Change Points in High-Dimensional Time Series via a Two-Way MOSUM". arXiv preprint <arXiv:2208.13074>.

This package provides tools for detecting and correcting sample mix-ups between two sets of measurements, such as between gene expression data on two tissues. This is a revised version of the lineup package, to be more general and not tied to the qtl package.

This package provides a flexible approach, inspired by cosinor regression, for differential analysis of rhythmic transcriptome data. See Singer and Hughey (2018) <doi:10.1177/0748730418813785>.

Estimate treatment-specific precision matrices (networks) from longitudinal high-dimensional normal data. The corresponding random effects are also estimated. It is motivated by the analysis of omics data in clinical trials where the longitudinal omics data becomes increasingly common. It includes both one-stage models (without treatment) and two-stage models (with one treatment). For details of the algorithms, please check the materials on its GitHub repo. If you have any questions, feel free to contact the maintainers through the email below.

Facilitates access to the Comparative Legislators Database (CLD). The CLD includes political, sociodemographic, career, online presence, public attention, and visual information for over 67,000 contemporary and historical politicians from 16 countries.

Transforms away factors with many levels prior to doing an OLS. Useful for estimating linear models with multiple group fixed effects, and for estimating linear models which uses factors with many levels as pure control variables. See Gaure (2013) <doi:10.1016/j.csda.2013.03.024> Includes support for instrumental variables, conditional F statistics for weak instruments, robust and multi-way clustered standard errors, as well as limited mobility bias correction (Gaure 2014 <doi:10.1002/sta4.68>). Since version 3.0, it provides dedicated functions to estimate Poisson models.

Error in a binary dependent variable, also known as misclassification, has not drawn much attention in psychology. Ignoring misclassification in logistic regression can result in misleading parameter estimates and statistical inference. This package conducts logistic regression analysis with misspecification in outcome variables.

This package contains different algorithms and construction methods for optimal Latin hypercube designs (LHDs) with flexible sizes. Our package is comprehensive since it is capable of generating maximin distance LHDs, maximum projection LHDs, and orthogonal and nearly orthogonal LHDs. Detailed comparisons and summary of all the algorithms and construction methods in this package can be found at Hongzhi Wang, Qian Xiao and Abhyuday Mandal (2021) <doi:10.48550/arXiv.2010.09154>. This package is particularly useful in the area of Design and Analysis of Experiments (DAE). More specifically, design of computer experiments.

This package provides a modular end-to-end framework for dynamic risk prediction based on time-to-event and longitudinal data. This allows flexible specifications for the longitudinal and survival sub-models. The landmaRk package enables reproducible benchmarks of different model choices, including cross-validation to assess out-of-sample predictive performance. Methods are described in Velasco-Pardo, Constantine-Cooke, Lees and Vallejos (2026, manuscript under preparation) Landmarking with Latent Class Mixed Models for Dynamic Prediction of Time-to-event Data with Heterogeneous Biomarker Trajectories'.

This package provides a system for fitting Logistic Curve by Rhodes Method. Method for fitting logistic curve by Rhodes Method is described in A.M.Gun,M.K.Gupta and B.Dasgupta(2019,ISBN:81-87567-81-3).

Given a postulated model and a set of data, the comparison density is estimated and the deviance test is implemented in order to assess if the data distribution deviates significantly from the postulated model. Finally, the results are summarized in a CD-plot as described in Algeri S. (2019) <arXiv:1906.06615>.

Linear dimension reduction subspaces can be uniquely defined using orthogonal projection matrices. This package provides tools to compute distances between such subspaces and to compute the average subspace. For details see Liski, E.Nordhausen K., Oja H., Ruiz-Gazen A. (2016) Combining Linear Dimension Reduction Subspaces <doi:10.1007/978-81-322-3643-6_7>.