Implementation of Multidimensional Top Scoring method for creativity assessment proposed in Boris Forthmann, Maciej Karwowski, Roger E. Beaty (2023) <doi:10.1037/aca0000571>.

This package provides a collection of functions for conducting meta-analysis using a structural equation modeling (SEM) approach via the OpenMx and lavaan packages. It also implements various procedures to perform meta-analytic structural equation modeling on the correlation and covariance matrices, see Cheung (2015) <doi:10.3389/fpsyg.2014.01521>.

This package provides a flexible framework for estimating the variance-covariance matrix of estimated parameters. Estimation relies on unbiased estimating functions to compute the empirical sandwich variance. (i.e., M-estimation in the vein of Tsiatis et al. (2019) <doi:10.1201/9780429192692>.

This package implements an Integer Programming-based method for optimising genetic gain in polyclonal selection, where the goal is to select a group of genotypes that jointly meet multi-trait selection criteria. The method uses predictors of genotypic effects obtained from the fitting of mixed models. Its application is demonstrated with grapevine data, but is applicable to other species and breeding contexts. For more details see Surgy et al. (2025) <doi:10.1007/s00122-025-04885-0>.

Identify and rank CpG DNA methylation conservation along the human genome. Specifically it includes bootstrapping methods to provide ranking which should adjust for the differences in length as without it short regions tend to get higher conservation scores.

This package provides a latent variable model based on factor analytic and mixture of experts models, designed to infer food intake from multiple biomarkers data. The model is framed within a Bayesian hierarchical framework, which provides flexibility to adapt to different biomarker distributions and facilitates inference on food intake from biomarker data alone, along with the associated uncertainty. Details are in D'Angelo, et al. (2020) <arXiv:2006.02995>.

This package provides a tool to simulate salmon metapopulations and apply financial portfolio optimization concepts. The package accompanies the paper Anderson et al. (2015) <doi:10.1101/2022.03.24.485545>.

This package implements the Mittag-Leffler function, distribution, random variate generation, and estimation. Based on the Laplace-Inversion algorithm by Garrappa, R. (2015) <doi:10.1137/140971191>.

This package provides a container for data used by the mapindia package. The data used by mapindia has been extracted into this package so that the file size of the mapindia package can be reduced considerably. The data in this package will be updated when latest data is available.

Hypothesis tests for multivariate data. Tests for one and two mean vectors, multivariate analysis of variance, tests for one, two or more covariance matrices. References include: Mardia K.V., Kent J.T. and Bibby J.M. (1979). Multivariate Analysis. ISBN: 978-0124712522. London: Academic Press.

An implementation of the Super Learner prediction algorithm from van der Laan, Polley, and Hubbard (2007) <doi:10.2202/1544-6115.1309 using the mlr3 framework.

This package provides a set of functions to calculate solar irradiance and insolation on Mars horizontal and inclined surfaces. Based on NASA Technical Memoranda 102299, 103623, 105216, 106321, and 106700, i.e. the canonical Mars solar radiation papers.

This package provides a way to estimate and test marginal mediation effects for zero-inflated compositional mediators. Estimates of Natural Indirect Effect (NIE), Natural Direct Effect (NDE) of each taxon, as well as their standard errors and confident intervals, were provided as outputs. Zeros will not be imputed during analysis. See Wu et al. (2022) <doi:10.3390/genes13061049>.

This package provides an extension of the shadow-test approach to computerized adaptive testing (CAT) implemented in the TestDesign package for the assessment framework involving multiple tests administered periodically throughout the year. This framework is referred to as the Multiple Administrations Adaptive Testing (MAAT) and supports multiple item pools vertically scaled and multiple phases (stages) of CAT within each test. Between phases and tests, transitioning from one item pool (and associated constraints) to another is allowed as deemed necessary to enhance the quality of measurement.

Quantify the causal effect of a binary exposure on a binary outcome with adjustment for multiple biases. The functions can simultaneously adjust for any combination of uncontrolled confounding, exposure/outcome misclassification, and selection bias. The underlying method generalizes the concept of combining inverse probability of selection weighting with predictive value weighting. Simultaneous multi-bias analysis can be used to enhance the validity and transparency of real-world evidence obtained from observational, longitudinal studies. Based on the work from Paul Brendel, Aracelis Torres, and Onyebuchi Arah (2023) <doi:10.1093/ije/dyad001>.

Find dark genes. These genes are often disregarded due to no detected mutation or differential expression, but are important in coordinating the functionality in cancer networks.

The sample mean and standard deviation are two commonly used statistics in meta-analyses, but some trials use other summary statistics such as the median and quartiles to report the results. Therefore, researchers need to transform those information back to the sample mean and standard deviation. This package implemented sample mean estimators by Luo et al. (2016) <arXiv:1505.05687>, sample standard deviation estimators by Wan et al. (2014) <arXiv:1407.8038>, and the best linear unbiased estimators (BLUEs) of location and scale parameters by Yang et al. (2018, submitted) based on sample quantiles derived summaries in a meta-analysis.

Framework for the Item Response Theory analysis of dichotomous and ordinal polytomous outcomes under the assumption of within-item multidimensionality and discreteness of the latent traits. The fitting algorithms allow for missing responses and for different item parametrizations and are based on the Expectation-Maximization paradigm. Individual covariates affecting the class weights may be included in the new version together with possibility of constraints on all model parameters.

This package provides a generalization of principal component analysis for integrative analysis. The method finds principal components that describe single matrices or that are common to several matrices. The solutions are sparse. Rank of solutions is automatically selected using cross validation. The method is described in Kallus et al. (2019) <doi:10.48550/arXiv.1911.04927>.

Distance between multivariate generalised Gaussian distributions, as presented by N. Bouhlel and A. Dziri (2019) <doi:10.1109/LSP.2019.2915000>. Manipulation of multivariate generalised Gaussian distributions (methods presented by Gomez, Gomez-Villegas and Marin (1998) <doi:10.1080/03610929808832115> and Pascal, Bombrun, Tourneret and Berthoumieu (2013) <doi:10.1109/TSP.2013.2282909>).

This package provides functionality for estimating cross-sectional network structures representing partial correlations while accounting for missing data. Networks are estimated via neighborhood selection or regularization, with model selection guided by information criteria. Missing data can be handled primarily via multiple imputation or a maximum likelihood-based approach, as demonstrated by Nehler and Schultze (2025a) <doi:10.31234/osf.io/qpj35> and Nehler and Schultze (2025b) <doi:10.1080/00273171.2025.2503833>. Deletion-based approaches are also available but play a secondary role.

Many tools for making, modifying, marking, measuring, and motifs and memberships of many different types of networks. All functions operate with matrices, edge lists, and igraph', network', and tidygraph objects, on directed, multiplex, multimodal, signed, and other networks. The package includes functions for importing and exporting, creating and generating networks, modifying networks and node and tie attributes, and describing networks with sensible defaults.

Researchers often have expectations about the relations between means of different groups or standardized regression coefficients; using informative hypothesis testing to incorporate these expectations into the analysis through order constraints increases statistical power Vanbrabant and Rosseel (2020) <doi:10.4324/9780429273872-14>. Another valuable tool, the Bayes factor, can evaluate evidence for multiple hypotheses without concerns about multiple testing, and can be used in Bayesian updating Hoijtink, Mulder, van Lissa & Gu (2019) <doi:10.1037/met0000201>. The bain R package enables informative hypothesis testing using the Bayes factor. The mmibain package provides shiny web applications based on bain'. The RepliCrisis() function launches a shiny card game to simulate the evaluation of replication studies while the mmibain() function launches a shiny application to fit Bayesian informative hypotheses evaluation models from bain'.

This package implements methods for post-hoc analysis and visualisation of benchmark experiments, for mlr3 and beyond.