This package contains functions to query and visualize the Neuroimaging features associated with genetically regulated gene expression (GReX). The primary utility, neuroimaGene(), relies on a list of user-defined genes and returns a table of neuroimaging features (NIDPs) associated with each gene. This resource is designed to assist in the interpretation of genome-wide and transcriptome-wide association studies that evaluate brain related traits. Bledsoe (2024) <doi:10.1016/j.ajhg.2024.06.002>. In addition there are several visualization functions that generate summary plots and 2-dimensional visualizations of regional brain measures. Mowinckel (2020).

Tidied data from the ASA 2006 data expo, as well as a number of useful other related data sets.

This package implements the non-asymptotically valid and asymptotically exact confidence intervals in two cases: estimation of the mean, and estimation of (a linear combination of) the coefficients in a linear regression model, following (Derumigny, Girard and Guyonvarch, 2025) <doi:10.48550/arXiv.2507.16776>.

Implementation of the NetCutter algorithm described in Müller and Mancuso (2008) <doi:10.1371/journal.pone.0003178>. The package identifies co-occurring terms in a list of containers. For example, it may be used to detect genes that co-occur across genomes.

This package provides a navigation menu to enable pipe-friendly data processing for hierarchical data structures. By activating the menu items, you can perform operations on each item while maintaining the overall structure in attributes.

This package provides a system for writing hierarchical statistical models largely compatible with BUGS and JAGS', writing nimbleFunctions to operate models and do basic R-style math, and compiling both models and nimbleFunctions via custom-generated C++. NIMBLE includes default methods for MCMC, Laplace Approximation, deterministic nested approximations, Monte Carlo Expectation Maximization, and some other tools. The nimbleFunction system makes it easy to do things like implement new MCMC samplers from R, customize the assignment of samplers to different parts of a model from R, and compile the new samplers automatically via C++ alongside the samplers NIMBLE provides. NIMBLE extends the BUGS'/'JAGS language by making it extensible: New distributions and functions can be added, including as calls to external compiled code. Although most people think of MCMC as the main goal of the BUGS'/'JAGS language for writing models, one can use NIMBLE for writing arbitrary other kinds of model-generic algorithms as well. A full User Manual is available at <https://r-nimble.org>.

We fit inverse probability weighting estimator and the augmented inverse probability weighting for non-monotone missing at random data.

This package provides automated methods for generating initial parameter estimates in population pharmacokinetic modeling. The pipeline integrates adaptive single-point methods, naive pooled graphic approaches, noncompartmental analysis methods, and parameter sweeping across pharmacokinetic models. It estimates residual unexplained variability using either data-driven or fixed-fraction approaches and assigns pragmatic initial values for inter-individual variability. These strategies are designed to improve model robustness and convergence in nlmixr2 workflows. For more details see Huang Z, Fidler M, Lan M, Cheng IL, Kloprogge F, Standing JF (2025) <doi:10.1007/s10928-025-10000-z>.

Package to select best model among several linear and nonlinear models. The main function uses the gnls() function from the nlme package to fit the data to nine regression models, named: "linear", "quadratic", "cubic", "logistic", "exponential", "power", "monod", "haldane", "logit".

This package provides access to the Native Status Resolver (NSR) <https://github.com/ojalaquellueva/nsr> API through R. The user supplies plant taxonomic names and political divisions and the package returns information about their likely native status (e.g., native, non-native,endemic), along with information on how those decisions were made.

This package implements the routines to compare the survival curves with recurrent events, including the estimations of survival curves. The first model is a model for recurrent event, when the data are correlated or not correlated. It was proposed by Wang and Chang (1999) <doi:10.2307/2669690>. In the independent case, the survival function can be estimated by the generalization of the limit product model of Pena (2001) <doi:10.1198/016214501753381922>.

Motivated by changing administrative boundaries over time, the nuts package can convert European regional data with NUTS codes between versions (2006, 2010, 2013, 2016 and 2021) and levels (NUTS 1, NUTS 2 and NUTS 3). The package uses spatial interpolation as in Lam (1983) <doi:10.1559/152304083783914958> based on granular (100m x 100m) area, population and land use data provided by the European Commission's Joint Research Center.

This package provides a nomogram can not be easily applied, because it is difficult to calculate the points or even the survival probability. The package, including a function of nomogramEx(), is to extract the polynomial equations to calculate the points of each variable, and the survival probability corresponding to the total points.

This package contains functions useful for debugging, set operations on vectors, and UTC date and time functionality. It adds a few vector manipulation verbs to purrr and dplyr packages. It can also generate an R file to install and update packages to simplify deployment into production. The functions were developed at the data science firm Numeract LLC and are used in several packages and projects.

This package provides a software package to perform Wombling, or boundary analysis, using the nimble Bayesian hierarchical modeling environment. Wombling is used widely to track regions of rapid change within the spatial reference domain. Specific functions in the package implement Gaussian process models for point-referenced spatial data followed by predictive inference on rates of change over curves using line integrals. We demonstrate model based Bayesian inference using posterior distributions featuring simple analytic forms while offering uncertainty quantification over curves. For more details on wombling please see, Banerjee and Gelfand (2006) <doi:10.1198/016214506000000041> and Halder, Banerjee and Dey (2024) <doi:10.1080/01621459.2023.2177166>.

Designed to create interactive and visually compelling network maps using R Shiny. It allows users to quickly analyze CSV files and visualize complex relationships, structures, and connections within data by leveraging powerful network analysis libraries and dynamic web interfaces.

Empirical statistical analysis, visualization and simulation of diffusion and contagion processes on networks. The package implements algorithms for calculating network diffusion statistics such as transmission rate, hazard rates, exposure models, network threshold levels, infectiousness (contagion), and susceptibility. The package is inspired by work published in Valente, et al., (2015) <DOI:10.1016/j.socscimed.2015.10.001>; Valente (1995) <ISBN: 9781881303213>, Myers (2000) <DOI:10.1086/303110>, Iyengar and others (2011) <DOI:10.1287/mksc.1100.0566>, Burt (1987) <DOI:10.1086/228667>; among others.

It provides a framework and a fast and simple way for researchers to evaluate methods (particularly some data-driven methods or their own methods) and then select a best one for data normalization in the gene expression analysis, based on the consistency of metrics and the consistency of datasets. Zhenfeng Wu, Weixiang Liu, Xiufeng Jin, Deshui Yu, Hua Wang, Gustavo Glusman, Max Robinson, Lin Liu, Jishou Ruan and Shan Gao (2018) <doi:10.1101/251140>.

Allow users to obtain basketball statistics for the Australian basketball league NBL'<https://nbl.com.au/>. Stats include play-by-play, shooting locations, results and box scores for teams and players.

Validate, format and compare identification numbers used in Brazil. These numbers are used to identify individuals (CPF), vehicles (RENAVAN), companies (CNPJ) and etc. Functions to format, validate and compare these numbers have been implemented in a vectorized way in order to speed up validations and comparisons in big datasets.

Estimates of coefficients of lasso penalized linear regression and generalized linear models subject to non-negativity constraints on the parameters using multiplicative iterative algorithm. Entire regularization path for a sequence of lambda values can be obtained. Functions are available for creating plots of regularization path, cross validation and estimating coefficients at a given lambda value. There is also provision for obtaining standard error of coefficient estimates.

We solve non linear least squares problems with optional equality and/or inequality constraints. Non linear iterations are globalized with back-tracking method. Linear problems are solved by dense QR decomposition from LAPACK which can limit the size of treated problems. On the other side, we avoid condition number degradation which happens in classical quadratic programming approach. Inequality constraints treatment on each non linear iteration is based on NNLS method (by Lawson and Hanson). We provide an original function lsi_ln for solving linear least squares problem with inequality constraints in least norm sens. Thus if Jacobian of the problem is rank deficient a solution still can be provided. However, truncation errors are probable in this case. Equality constraints are treated by using a basis of Null-space. User defined function calculating residuals must return a list having residual vector (not their squared sum) and Jacobian. If Jacobian is not in the returned list, package numDeriv is used to calculated finite difference version of Jacobian. The NLSIC method was fist published in Sokol et al. (2012) <doi:10.1093/bioinformatics/btr716>.

Calculate various functions needed for design and monitoring clinical trials with negative binomial endpoint with variable follow-up. This version has a few changes compared to the previous version 1.0.0, including (1) correct a typo in Type 1 censoring, mtbnull=bnull and (2) restructure the code to account for shape parameter equal to zero, i.e. Poisson scenario.

This package provides functions to query databases and notes in Notion', using the official REST API. To learn more about the functionality of the Notion API, see <https://developers.notion.com/>.