This package provides utilities for processing of Oxy-Bisulfite microarray data (e.g. via the Illumina Infinium platform, <http://www.illumina.com>) with tandem arrays, one using conventional bisulfite conversion, the other using oxy-bisulfite conversion.

This package provides a single function options.ifunset(...) is contained herewith, which allows the user to set a global option ONLY if it is not already set. By this token, for package maintainers this function can be used in preference to the standard options(...) function, making provision for THEIR end user to place options(...) directives within their .Rprofile file, which will not be overridden at the point when a package is loaded.

Sequential outlier identification for Gaussian mixture models using the distribution of Mahalanobis distances. The optimal number of outliers is chosen based on the dissimilarity between the theoretical and observed distributions of the scaled squared sample Mahalanobis distances. Also includes an extension for Gaussian linear cluster-weighted models using the distribution of studentized residuals. Doherty, McNicholas, and White (2025) <doi:10.48550/arXiv.2505.11668>.

An interface for interacting with OSF (<https://osf.io>). osfr enables you to access open research materials and data, or create and manage your own private or public projects.

Distance based bipartite matching using minimum cost flow, oriented to matching of treatment and control groups in observational studies ('Hansen and Klopfer 2006 <doi:10.1198/106186006X137047>). Routines are provided to generate distances from generalised linear models (propensity score matching), formulas giving variables on which to limit matched distances, stratified or exact matching directives, or calipers, alone or in combination.

The openFDA API facilitates access to Federal Drug Agency (FDA) data on drugs, devices, foodstuffs, tobacco, and more with httr2'. This package makes the API easily accessible, returning objects which the user can convert to JSON data and parse. Kass-Hout TA, Xu Z, Mohebbi M et al. (2016) <doi:10.1093/jamia/ocv153>.

The log-rank test is performed to assess the survival outcomes between two group. When there is no proper control group or obtaining such data is cumbersome, one sample log-rank test can be applied. This package performs one sample log-rank test as described in Finkelstein et al. (2003)<doi:10.1093/jnci/djt227> and variation of the test for small sample sizes which is detailed in FD Liddell (1984)<doi:10.1136/jech.38.1.85> paper. Visualization function in the package generates Kaplan-Meier Curve comparing survival curve of the general population against that of the population of interest.

Medication adherence, defined as medication-taking behavior that aligns with the agreed-upon treatment protocol, is critical for realizing the benefits of prescription medications. Medication adherence can be assessed using electronic adherence monitoring devices (EAMDs), pill bottles or boxes that contain a computer chip that records the date and time of each opening (or â actuationâ ). Before researchers can use EAMD data, they must apply a series of decision rules to transform actuation data into adherence data. The purpose of this R package ('oncmap') is to transform EAMD actuations in the form of a raw .csv file, information about the patient, regimen, and non-monitored periods into two daily adherence values -- Dose Taken and Correct Dose Taken.

Calculates ordinated diet breadth with some plotting functions.

We provide an R interface to OpenML.org which is an online machine learning platform where researchers can access open data, download and upload data sets, share their machine learning tasks and experiments and organize them online to work and collaborate with other researchers. The R interface allows to query for data sets with specific properties, and allows the downloading and uploading of data sets, tasks, flows and runs. See <https://www.openml.org/guide/api> for more information.

Subsampling based variable selection for low dimensional generalized linear models. The methods repeatedly subsample the data minimizing an information criterion (AIC/BIC) over a sequence of nested models for each subsample. Marinela Capanu, Mihai Giurcanu, Colin B Begg, Mithat Gonen, Subsampling based variable selection for generalized linear models.

The online principal component regression method can process the online data set. OPCreg implements the online principal component regression method, which is specifically designed to process online datasets efficiently. This method is particularly useful for handling large-scale, streaming data where traditional batch processing methods may be computationally infeasible.The philosophy of the package is described in Guo (2025) <doi:10.1016/j.physa.2024.130308>.

This package provides a visualization tool for multivariate data. This package maintains the original functionality of a radar chart and avoids potential misuse of its connected regions, with newly added features to better assist multi-criteria decision-making.

Oblique random survival forests incorporate linear combinations of input variables into random survival forests (Ishwaran, 2008 <DOI:10.1214/08-AOAS169>). Regularized Cox proportional hazard models (Simon, 2016 <DOI:10.18637/jss.v039.i05>) are used to identify optimal linear combinations of input variables.

Estimates one-inflated positive Poisson (OIPP) and one-inflated zero-truncated negative binomial (OIZTNB) regression models. A suite of ancillary statistical tools are also provided, including: estimation of positive Poisson (PP) and zero-truncated negative binomial (ZTNB) models; marginal effects and their standard errors; diagnostic likelihood ratio and Wald tests; plotting; predicted counts and expected responses; and random variate generation. The models and tools, as well as four applications, are shown in Godwin, R. T. (2024). "One-inflated zero-truncated count regression models" arXiv preprint <doi:10.48550/arXiv.2402.02272>.

Model mixed integer linear programs in an algebraic way directly in R. The model is solver-independent and thus offers the possibility to solve a model with different solvers. It currently only supports linear constraints and objective functions. See the ompr website <https://dirkschumacher.github.io/ompr/> for more information, documentation and examples.

Package for estimating the parameters of a nonlinear function using iterated linearization via Taylor series. Method is based on KubÃ¡Ä ek (2000) ISBN: 80-244-0093-6. The algorithm is a generalization of the procedure given in Köning, R., Wimmer, G. and Witkovský, V. (2014) <doi:10.1088/0957-0233/25/11/115001>.

Distributed reproducible computing framework, adopting ideas from git, docker and other software. By defining a lightweight interface around the inputs and outputs of an analysis, a lot of the repetitive work for reproducible research can be automated. We define a simple format for organising and describing work that facilitates collaborative reproducible research and acknowledges that all analyses are run multiple times over their lifespans.

Plotting toolbox for 2D oceanographic data (satellite data, sea surface temperature, chlorophyll, ocean fronts & bathymetry). Recognized classes and formats include netcdf, Raster, .nc and .gz files.

This package provides a database management tool built as a shiny application. Connect to various databases to send queries, upload files, preview tables, and more.

Optimal Subset Cardinality Regression (OSCAR) models offer regularized linear regression using the L0-pseudonorm, conventionally known as the number of non-zero coefficients. The package estimates an optimal subset of features using the L0-penalization via cross-validation, bootstrapping and visual diagnostics. Effective Fortran implementations are offered along the package for finding optima for the DC-decomposition, which is used for transforming the discrete L0-regularized optimization problem into a continuous non-convex optimization task. These optimization modules include DBDC ('Double Bundle method for nonsmooth DC optimization as described in Joki et al. (2018) <doi:10.1137/16M1115733>) and LMBM ('Limited Memory Bundle Method for large-scale nonsmooth optimization as in Haarala et al. (2004) <doi:10.1080/10556780410001689225>). The OSCAR models are comprehensively exemplified in Halkola et al. (2023) <doi:10.1371/journal.pcbi.1010333>). Multiple regression model families are supported: Cox, logistic, and Gaussian.

Maximum homogeneity clustering algorithm for one-dimensional data described in W. D. Fisher (1958) <doi:10.1080/01621459.1958.10501479> via dynamic programming.

Solver for linear, quadratic, and rational programs with linear, quadratic, and rational constraints. A unified interface to different R packages is provided. Optimization problems are transformed into equivalent formulations and solved by the respective package. For example, quadratic programming problems with linear, quadratic and rational constraints can be solved by augmented Lagrangian minimization using package alabama', or by sequential quadratic programming using solver slsqp'. Alternatively, they can be reformulated as optimization problems with second order cone constraints and solved with package cccp'.

This package provides implementations of some of the most important outlier detection algorithms. Includes a tutorial mode option that shows a description of each algorithm and provides a step-by-step execution explanation of how it identifies outliers from the given data with the specified input parameters. References include the works of Azzedine Boukerche, Lining Zheng, and Omar Alfandi (2020) <doi:10.1145/3381028>, Abir Smiti (2020) <doi:10.1016/j.cosrev.2020.100306>, and Xiaogang Su, Chih-Ling Tsai (2011) <doi:10.1002/widm.19>.