This package provides methods for performing genetic risk prediction from genotype data. You can use it to perform risk prediction for individuals, or for families with missing data.

This package provides a new approach to detect change points based on smoothing and multiple testing, which is for long data sequence modeled as piecewise constant functions plus stationary Gaussian noise, see Dan Cheng and Armin Schwartzman (2015) <arXiv:1504.06384>.

The MIMS-unit algorithm is developed to compute Monitor Independent Movement Summary Unit, a measurement to summarize raw accelerometer data while ensuring harmonized results across different devices. It also includes scripts to reproduce results in the related publication (John, D., Tang. Q., Albinali, F. and Intille, S. (2019) <doi:10.1123/jmpb.2018-0068>).

This package provides a procedure for comparing multivariate samples associated with different groups. It uses principal component analysis to convert multivariate observations into a set of linearly uncorrelated statistical measures, which are then compared using a number of statistical methods. The procedure is independent of the distributional properties of samples and automatically selects features that best explain their differences, avoiding manual selection of specific points or summary statistics. It is appropriate for comparing samples of time series, images, spectrometric measures or similar multivariate observations. This package is described in Fachada et al. (2016) <doi:10.32614/RJ-2016-055>.

This package provides a number of testthat tests that can be used to verify that tidy(), glance() and augment() methods meet consistent specifications. This allows methods for the same generic to be spread across multiple packages, since all of those packages can make the same guarantees to users about returned objects.

This package implements order selection for Vector Autoregressive (VAR) models using the Mean Square Information Criterion (MIC). Unlike standard methods such as AIC and BIC, MIC is likelihood-free. This method consistently estimates VAR order and has robust performance under model misspecification. For more details, see Hellstern and Shojaie (2025) <doi:10.48550/arXiv.2511.19761>.

Supports Bayesian models with full and partial (hence arbitrary) dependencies between random variables. Discrete and continuous variables are supported, and conditional joint probabilities and probability densities are estimated using Kernel Density Estimation (KDE). The full general form, which implements an extension to Bayes theorem, as well as the simple form, which is just a Bayesian network, both support regression through segmentation and KDE and estimation of probability or relative likelihood of discrete or continuous target random variables. This package also provides true statistical distance measures based on Bayesian models. Furthermore, these measures can be facilitated on neighborhood searches, and to estimate the similarity and distance between data points. Related work is by Bayes (1763) <doi:10.1098/rstl.1763.0053> and by Scutari (2010) <doi:10.18637/jss.v035.i03>.

Clean the MS/MS spectrum, calculate spectral entropy, unweighted entropy similarity, and entropy similarity for mass spectrometry data. The entropy similarity is a novel similarity measure for MS/MS spectra which outperform the widely used dot product similarity in compound identification. For more details, please refer to the paper: Yuanyue Li et al. (2021) "Spectral entropy outperforms MS/MS dot product similarity for small-molecule compound identification" <doi:10.1038/s41592-021-01331-z>.

Allows the user to generate a friendly user interface for emails sending. The user can choose from the most popular free email services ('Gmail', Outlook', Yahoo') and his default email application. The package is a wrapper for the Mailtoui JavaScript library. See <https://mailtoui.com/#menu> for more information.

Several robust estimators for linear regression and variable selection are provided. Included are Maximum tangent likelihood estimator by Qin, et al., (2017), arXiv preprint <doi:10.48550/arXiv.1708.05439>, least absolute deviance estimator and Huber regression. The penalized version of each of these estimator incorporates L1 penalty function, i.e., LASSO and Adaptive Lasso. They are able to produce consistent estimates for both fixed and high-dimensional settings.

Sends supported R objects to the Mellio web app and creates polished, editable statistical tables in R'. The mellio_open interface handles common hypothesis tests, model objects, model comparisons, descriptive summaries, tabular data, plots, and image files. The melliotab interface formats data frames, model summaries, correlation matrices, and side-by-side comparison tables with APA-style numeric formatting, confidence intervals, table notes, and optional significance markers. Manual table helpers can copy or save melliotab output as HTML', LaTeX', or Markdown when file-based handoff is needed. Payloads include package-version metadata to support reproducible reporting and software citation.

Computes mutual information matrices from continuous, categorical and survival variables, as well as feature selection with minimum redundancy, maximum relevance (mRMR) and a new ensemble mRMR technique. Published in De Jay et al. (2013) <doi:10.1093/bioinformatics/btt383>.

Estimating wind speed from trajectories of individually tracked birds using a maximum likelihood approach.

This package provides graph-constrained regression methods in which regularization parameters are selected automatically via estimation of equivalent Linear Mixed Model formulation. riPEER (ridgified Partially Empirical Eigenvectors for Regression) method employs a penalty term being a linear combination of graph-originated and ridge-originated penalty terms, whose two regularization parameters are ML estimators from corresponding Linear Mixed Model solution; a graph-originated penalty term allows imposing similarity between coefficients based on graph information given whereas additional ridge-originated penalty term facilitates parameters estimation: it reduces computational issues arising from singularity in a graph-originated penalty matrix and yields plausible results in situations when graph information is not informative. riPEERc (ridgified Partially Empirical Eigenvectors for Regression with constant) method utilizes addition of a diagonal matrix multiplied by a predefined (small) scalar to handle the non-invertibility of a graph Laplacian matrix. vrPEER (variable reducted PEER) method performs variable-reduction procedure to handle the non-invertibility of a graph Laplacian matrix.

Given a set of data points, a clustering is defined as a disjoint partition where each pair of sets in a partition has no overlapping elements. This package provides 25 methods that play a role somewhat similar to distance or metric that measures similarity of two clusterings - or partitions. For a more detailed description, see Meila, M. (2005) <doi:10.1145/1102351.1102424>.

Fit Maximum Entropy Optimality Theory models to data sets, generate the predictions made by such models for novel data, and compare the fit of different models using a variety of metrics. The package is described in Mayer, C., Tan, A., Zuraw, K. (in press) <https://sites.socsci.uci.edu/~cjmayer/papers/cmayer_et_al_maxent_ot_accepted.pdf>.

This package provides tools to generate random landscape graphs, evaluate species occurrence in dynamic landscapes, simulate future landscape occupation and evaluate range expansion when new empty patches are available (e.g. as a result of climate change). References: Mestre, F., Canovas, F., Pita, R., Mira, A., Beja, P. (2016) <doi:10.1016/j.envsoft.2016.03.007>; Mestre, F., Risk, B., Mira, A., Beja, P., Pita, R. (2017) <doi:10.1016/j.ecolmodel.2017.06.013>; Mestre, F., Pita, R., Mira, A., Beja, P. (2020) <doi:10.1186/s12898-019-0273-5>.

This package creates and runs Bayesian mixing models to analyze biological tracer data (i.e. stable isotopes, fatty acids), which estimate the proportions of source (prey) contributions to a mixture (consumer). MixSIAR is not one model, but a framework that allows a user to create a mixing model based on their data structure and research questions, via options for fixed/ random effects, source data types, priors, and error terms. MixSIAR incorporates several years of advances since MixSIR and SIAR'.

Find common entities detected in both positive and negative ionization mode, delete this entity in the less sensible mode and combine both matrices.

Function ModEstM() is the only one of this package, it estimates the modes of an empirical univariate distribution. It relies on the stats::density() function, even for input control. Due to very good performance of the density estimation, computation time is not an issue. The multiple modes are handled using dplyr::group_by(). For conditions and rates of convergences, see Eddy (1980) <doi:10.1214/aos/1176345080>.

Two method new of multigroup and simulation of data. The first technique called multigroup PCA (mgPCA) this multivariate exploration approach that has the idea of considering the structure of groups and / or different types of variables. On the other hand, the second multivariate technique called Multigroup Dimensionality Reduction (MDR) it is another multivariate exploration method that is based on projections. In addition, a method called Single Dimension Exploration (SDE) was incorporated for to analyze the exploration of the data. It could help us in a better way to observe the behavior of the multigroup data with certain variables of interest.

This package provides tools for phase-type distributions including the following variants: continuous, discrete, multivariate, in-homogeneous, right-censored, and regression. Methods for functional evaluation, simulation and estimation using the expectation-maximization (EM) algorithm are provided for all models. The methods of this package are based on the following references. Asmussen, S., Nerman, O., & Olsson, M. (1996). Fitting phase-type distributions via the EM algorithm, Olsson, M. (1996). Estimation of phase-type distributions from censored data, Albrecher, H., & Bladt, M. (2019) <doi:10.1017/jpr.2019.60>, Albrecher, H., Bladt, M., & Yslas, J. (2022) <doi:10.1111/sjos.12505>, Albrecher, H., Bladt, M., Bladt, M., & Yslas, J. (2022) <doi:10.1016/j.insmatheco.2022.08.001>, Bladt, M., & Yslas, J. (2022) <doi:10.1080/03461238.2022.2097019>, Bladt, M. (2022) <doi:10.1017/asb.2021.40>, Bladt, M. (2023) <doi:10.1080/10920277.2023.2167833>, Albrecher, H., Bladt, M., & Mueller, A. (2023) <doi:10.1515/demo-2022-0153>, Bladt, M. & Yslas, J. (2023) <doi:10.1016/j.insmatheco.2023.02.008>.

This package provides a unified and consistent S3 interface for training and predicting with a variety of machine learning models in R. The package wraps popular algorithms (e.g., from glmnet', lightgbm', ranger', e1071', and caret') under a common workflow based on simple wrap_*() and predict() functions, allowing users to switch between models without changing their code structure. It supports both classification and regression tasks and facilitates rapid experimentation, benchmarking, and comparison of models. By abstracting away package-specific APIs while preserving flexibility in parameter specification, the package streamlines machine learning workflows and promotes reproducibility.

This package provides a novel mediation analysis approach to address zero-inflated mediators containing true zeros and false zeros. See Jiang et al (2023) "A Novel Causal Mediation Analysis Approach for Zero-Inflated Mediators" <arXiv:2301.10064> for more details.