Simple interface routines to facilitate the handling of network objects with complex intertemporal data. This is a part of the "statnet" suite of packages for network analysis.

In shotgun proteomics, shared peptides (i.e., peptides that might originate from different proteins sharing homology, from different proteoforms due to alternative mRNA splicing, post-translational modifications, proteolytic cleavages, and/or allelic variants) represent a major source of ambiguity in protein identifications. The net4pg package allows to assess and handle ambiguity of protein identifications. It implements methods for two main applications. First, it allows to represent and quantify ambiguity of protein identifications by means of graph connected components (CCs). In graph theory, CCs are defined as the largest subgraphs in which any two vertices are connected to each other by a path and not connected to any other of the vertices in the supergraph. Here, proteins sharing one or more peptides are thus gathered in the same CC (multi-protein CC), while unambiguous protein identifications constitute CCs with a single protein vertex (single-protein CCs). Therefore, the proportion of single-protein CCs and the size of multi-protein CCs can be used to measure the level of ambiguity of protein identifications. The package implements a strategy to efficiently calculate graph connected components on large datasets and allows to visually inspect them. Secondly, the net4pg package allows to exploit the increasing availability of matched transcriptomic and proteomic datasets to reduce ambiguity of protein identifications. More precisely, it implement a transcriptome-based filtering strategy fundamentally consisting in the removal of those proteins whose corresponding transcript is not expressed in the sample-matched transcriptome. The underlying assumption is that, according to the central dogma of biology, there can be no proteins without the corresponding transcript. Most importantly, the package allows to visually inspect the effect of the filtering on protein identifications and quantify ambiguity before and after filtering by means of graph connected components. As such, it constitutes a reproducible and transparent method to exploit transcriptome information to enhance protein identifications. All methods implemented in the net4pg package are fully described in Fancello and Burger (2022) <doi:10.1186/s13059-022-02701-2>.

Performing drug response analyses and IC50 estimations using n-Parameter logistic regression. Can also be applied to proliferation analyses.

Probabilistic time series forecasting via Natural Gradient Boosting for Probabilistic Prediction.

This package implements statistical tools for analyzing, simulating, and computing properties of the New Topp-Leone Kumaraswamy Inverse Exponential (NTLKwIEx) distribution. See Atchadé M, Otodji T, and Djibril A (2024) <doi:10.1063/5.0179458> and Atchadé M, Otodji T, Djibril A, and N'bouké M (2023) <doi:10.1515/phys-2023-0151> for details.

Several methods have been developed to integrate structural equation modeling techniques with network data analysis to examine the relationship between network and non-network data. Both node-based and edge-based information can be extracted from the network data to be used as observed variables in structural equation modeling. To facilitate the application of these methods, model specification can be performed in the familiar syntax of the lavaan package, ensuring ease of use for researchers. Technical details and examples can be found at <https://bigsem.psychstat.org>.

Illustrate graphically the most common Null Hypothesis Significance Testing procedures. More specifically, this package provides functions to plot Chi-Squared, F, t (one- and two-tailed) and z (one- and two-tailed) tests, by plotting the probability density under the null hypothesis as a function of the different test statistic values. Although highly flexible (color theme, fonts, etc.), only the minimal number of arguments (observed test statistic, degrees of freedom) are necessary for a clear and useful graph to be plotted, with the observed test statistic and the p value, as well as their corresponding value labels. The axes are automatically scaled to present the relevant part and the overall shape of the probability density function. This package is especially intended for education purposes, as it provides a helpful support to help explain the Null Hypothesis Significance Testing process, its use and/or shortcomings.

The ntfy (pronounce: notify) service is a simple HTTP-based pub-sub notification service. It allows you to send notifications to your phone or desktop via scripts from any computer, entirely without signup, cost or setup. It's also open source if you want to run your own. Visit <https://ntfy.sh> for more details.

This package provides standardized access to a range of re-scaling methods for numerical vectors and time-series features calculated within the theft ecosystem.

Nonparametric maximum likelihood estimation or Gaussian quadrature for overdispersed generalized linear models and variance component models.

Utility to retrieve data from the National Health and Nutrition Examination Survey (NHANES) website <https://www.cdc.gov/nchs/nhanes/>.

Automated population pharmacokinetic modeling framework for data-driven initialisation, model evaluation, and metaheuristic optimization. Supports genetic algorithms, ant colony optimization, tabu search, and stepwise procedures for automated model selection and parameter estimation within the nlmixr2 ecosystem.

Adding updates (version or bullet points) to the NEWS.md file.

This package provides utility functions, distributions, and fitting methods for Bayesian Spatial Capture-Recapture (SCR) and Open Population Spatial Capture-Recapture (OPSCR) modelling using the nimble package (de Valpine et al. 2017 <doi:10.1080/10618600.2016.1172487 >). Development of the package was motivated primarily by the need for flexible and efficient analysis of large-scale SCR data (Bischof et al. 2020 <doi:10.1073/pnas.2011383117 >). Computational methods and techniques implemented in nimbleSCR include those discussed in Turek et al. 2021 <doi:10.1002/ecs2.3385>; among others. For a recent application of nimbleSCR, see Milleret et al. (2021) <doi:10.1098/rsbl.2021.0128>.

Social network analysis has become an essential tool in the study of complex systems. NetExplorer allows to visualize and explore complex systems. It is based on d3js library that brings 1) Graphical user interface; 2) Circular, linear, multilayer and force Layout; 3) Network live exploration and 4) SVG exportation.

Nonparametric Tests for Main Effects, Simple Effects and Interaction Effect with Censored Data and Two Factorial Influencing Variables.

Th-U-Pb electron microprobe age dating of monazite, as originally described in <doi:10.1016/0009-2541(96)00024-1>.

Conduct inference on the sample average treatment effect for a matched (observational) dataset with a continuous treatment. Equipped with calipered non-bipartite matching, bias-corrected sample average treatment effect estimation, and covariate-adjusted variance estimation. Matching, estimation, and inference methods are described in Frazier, Heng and Zhou (2024) <doi:10.48550/arXiv.2409.11701>.

Features tools for the network data analysis and community detection. Provides multiple methods for fitting, model selection and goodness-of-fit testing in degree-corrected stochastic blocks models. Most of the computations are fast and scalable for sparse networks, esp. for Poisson versions of the models. Implements the following: Amini, Chen, Bickel and Levina (2013) <doi:10.1214/13-AOS1138> Bickel and Sarkar (2015) <doi:10.1111/rssb.12117> Lei (2016) <doi:10.1214/15-AOS1370> Wang and Bickel (2017) <doi:10.1214/16-AOS1457> Zhang and Amini (2020) <arXiv:2012.15047> Le and Levina (2022) <doi:10.1214/21-EJS1971>.

National Statistical Office of Mongolia (NSO) is the national statistical service and an organization of Mongolian government. NSO provides open access to official data via its API <http://opendata.1212.mn/en/doc>. The package NSO1212 has functions for accessing the API service. The functions are compatible with the API v2.0 and get data sets and its detailed informations from the API.

Uses a modified lifting algorithm on which it builds the nondecimated lifting transform. It has applications in wavelet shrinkage.

Linear regression model and generalized linear models with nonparametric network effects on network-linked observations. The model is originally proposed by Le and Li (2022) <doi:10.48550/arXiv.2007.00803> and is assumed on observations that are connected by a network or similar relational data structure. A more recent work by Wang, Le and Li (2024) <doi:10.48550/arXiv.2410.01163> further extends the framework to generalized linear models. All these models are implemented in the current package. The model does not assume that the relational data or network structure to be precisely observed; thus, the method is provably robust to a certain level of perturbation of the network structure. The package contains the estimation and inference function for the model.

This package provides measures to describe and manipulate one-mode, two-mode, multiplex, and multilevel networks using matrix algebra. Implements functions for network centrality, cohesive subgroups, structural holes, similarity measures, path distances, signed networks, and random network generation. Supports ego-centric and whole-network analyses, including dyadic and triadic census, structural balance, and bipartite projections. Key references: Bonacich (1972) <doi:10.1080/0022250X.1972.9989806>, Breiger (1974) <doi:10.2307/2576011>, Kivelä et al. (2014) <doi:10.1093/comnet/cnu016>, Espinosa-Rada et al. (2024) <doi:10.1016/j.socnet.2023.11.008>.

Different inference procedures are proposed in the literature to correct for selection bias that might be introduced with non-random selection mechanisms. A class of methods to correct for selection bias is to apply a statistical model to predict the units not in the sample (super-population modeling). Other studies use calibration or Statistical Matching (statistically match nonprobability and probability samples). To date, the more relevant methods are weighting by Propensity Score Adjustment (PSA). The Propensity Score Adjustment method was originally developed to construct weights by estimating response probabilities and using them in Horvitzâ Thompson type estimators. This method is usually used by combining a non-probability sample with a reference sample to construct propensity models for the non-probability sample. Calibration can be used in a posterior way to adding information of auxiliary variables. Propensity scores in PSA are usually estimated using logistic regression models. Machine learning classification algorithms can be used as alternatives for logistic regression as a technique to estimate propensities. The package NonProbEst implements some of these methods and thus provides a wide options to work with data coming from a non-probabilistic sample.