The nflverse is a set of packages dedicated to data of the National Football League. This package is designed to make it easy to install and load multiple nflverse packages in a single step. Learn more about the nflverse at <https://nflverse.nflverse.com/>.

Imputation for both missing covariates and censored observations (optional) for survival data with missing covariates by the nearest neighbor based multiple imputation algorithm as described in Hsu et al. (2006) <doi:10.1002/sim.2452>, and Hsu and Yu (2018) <doi: 10.1177/0962280218772592>. Note that the current version can only impute for a situation with one missing covariate.

Allele frequency databases for 50 forensic short tandem repeat (STR) markers, covering Norway and several broader regional populations: Europe, Africa, South America, West Asia, Middle Asia, and East Asia. Developed and maintained for use at the Department of Forensic Sciences, Oslo, Norway.

Facilitates nonresponse bias analysis (NRBA) for survey data. Such data may arise from a complex sampling design with features such as stratification, clustering, or unequal probabilities of selection. Multiple types of analyses may be conducted: comparisons of response rates across subgroups; comparisons of estimates before and after weighting adjustments; comparisons of sample-based estimates to external population totals; tests of systematic differences in covariate means between respondents and full samples; tests of independence between response status and covariates; and modeling of outcomes and response status as a function of covariates. Extensive documentation and references are provided for each type of analysis. Krenzke, Van de Kerckhove, and Mohadjer (2005) <http://www.asasrms.org/Proceedings/y2005/files/JSM2005-000572.pdf> and Lohr and Riddles (2016) <https://www150.statcan.gc.ca/n1/en/pub/12-001-x/2016002/article/14677-eng.pdf?st=q7PyNsGR> provide an overview of the methods implemented in this package.

Subsampling methods for big data under different models and assumptions. Starting with linear regression and leading to Generalised Linear Models, softmax regression, and quantile regression. Specifically, the model-robust subsampling method proposed in Mahendran, A., Thompson, H., and McGree, J. M. (2023) <doi:10.1007/s00362-023-01446-9>, where multiple models can describe the big data, and the subsampling framework for potentially misspecified Generalised Linear Models in Mahendran, A., Thompson, H., and McGree, J. M. (2025) <doi:10.48550/arXiv.2510.05902>.

Includes functions and examples to compute NEAT, the Network Enrichment Analysis Test described in Signorelli et al. (2016, <DOI:10.1186/s12859-016-1203-6>).

Omics data come in different forms: gene expression, methylation, copy number, protein measurements and more. NCutYX allows clustering of variables, of samples, and both variables and samples (biclustering), while incorporating the dependencies across multiple types of Omics data. (SJ Teran Hidalgo et al (2017), <doi:10.1186/s12864-017-3990-1>).

Interface to the National Weather Service operational hydrology models, Sacramento Soil Moisture Accounting (SAC-SMA), Snow Accumulation and Ablation (SNOW17). Also provides an interface to the unit hydrograph routing model (UH), consumptive use (CONSUSE) and channel loss/gain modules (CHANLOSS). The Fortran code used in this package is considered "legacy" and is not supported officially by NWS, but it should not have any significant differences from current operational models.

Simulate DNA sequences for the node substitution model. In the node substitution model, substitutions accumulate additionally during a speciation event, providing a potential mechanistic explanation for substitution rate variation. This package provides tools to simulate such a process, simulate a reference process with only substitutions along the branches, and provides tools to infer phylogenies from alignments. More information can be found in Janzen (2021) <doi:10.1093/sysbio/syab085>.

Cross-Entropy optimisation of unconstrained deterministic and noisy functions illustrated in Rubinstein and Kroese (2004, ISBN: 978-1-4419-1940-3) through a highly flexible and customisable function which allows user to define custom variable domains, sampling distributions, updating and smoothing rules, and stopping criteria. Several built-in methods and settings make the package very easy-to-use under standard optimisation problems.

Nonparametric methods for smoothing regression function data with change-points, utilizing range kernels for iterative and anisotropic smoothing methods. For further details, see the paper by John R.J. Thompson (2024) <doi:10.1080/02664763.2024.2352759>.

The intent here is to enable the simulation of plays/drives and evaluate game-play strategies in the National Football League (NFL). Built-in strategies include going for it on fourth down and varying the proportion of passing/rushing plays during a drive. The user should be familiar with nflscrapR data before trying to write his/her own strategies. This work is inspired by a blog post by Mike Lopez, currently the Director of Data and Analytics at the NFL, Lopez (2019) <https://statsbylopez.netlify.app/post/resampling-nfl-drives/>.

Cleans and Normalizes FLUOstar DBF and DAT Files obtained from liposome flux assays. Users should verify extended usage of the package on files from other assay types.

Implementation of a probabilistic method to calculate nicheROVER (_niche_ _r_egion and niche _over_lap) metrics using multidimensional niche indicator data (e.g., stable isotopes, environmental variables, etc.). The niche region is defined as the joint probability density function of the multidimensional niche indicators at a user-defined probability alpha (e.g., 95%). Uncertainty is accounted for in a Bayesian framework, and the method can be extended to three or more indicator dimensions. It provides directional estimates of niche overlap, accounts for species-specific distributions in multivariate niche space, and produces unique and consistent bivariate projections of the multivariate niche region. The article by Swanson et al. (2015) <doi:10.1890/14-0235.1> provides a detailed description of the methodology. See the package vignette for a worked example using fish stable isotope data.

This package provides a number of statistical tests have been proposed to compare two survival curves, including the difference in (or ratio of) t-year survival, difference in (or ratio of) p-th percentile survival, difference in (or ratio of) restricted mean survival time, and the weighted log-rank test. Despite the multitude of options, the convention in survival studies is to assume proportional hazards and to use the unweighted log-rank test for design and analysis. This package provides sample size and power calculation for all of the above statistical tests with allowance for flexible accrual, censoring, and survival (eg. Weibull, piecewise-exponential, mixture cure). It is the companion R package to the paper by Yung and Liu (2020) <doi:10.1111/biom.13196>. Specific to the weighted log-rank test, users may specify which approximations they wish to use to estimate the large-sample mean and variance. The default option has been shown to provide substantial improvement over the conventional sample size and power equations based on Schoenfeld (1981) <doi:10.1093/biomet/68.1.316>.

Instant access to harmonized National Health and Nutrition Examination Survey (NHANES) data spanning 1999-2023. Retrieve pre-processed datasets from reliable cloud storage with automatic type reconciliation and integrated search tools for variables and datasets. Simplifies NHANES data workflows by handling cycle management and maintaining data consistency across survey waves. Data is sourced from <https://www.cdc.gov/nchs/nhanes/>.

This package provides utility functions, distributions, and fitting methods for Bayesian Spatial Capture-Recapture (SCR) and Open Population Spatial Capture-Recapture (OPSCR) modelling using the nimble package (de Valpine et al. 2017 <doi:10.1080/10618600.2016.1172487 >). Development of the package was motivated primarily by the need for flexible and efficient analysis of large-scale SCR data (Bischof et al. 2020 <doi:10.1073/pnas.2011383117 >). Computational methods and techniques implemented in nimbleSCR include those discussed in Turek et al. 2021 <doi:10.1002/ecs2.3385>; among others. For a recent application of nimbleSCR, see Milleret et al. (2021) <doi:10.1098/rsbl.2021.0128>.

This package provides several direct search optimization algorithms based on the simplex method. The provided algorithms are direct search algorithms, i.e. algorithms which do not use the derivative of the cost function. They are based on the update of a simplex. The following algorithms are available: the fixed shape simplex method of Spendley, Hext and Himsworth (unconstrained optimization with a fixed shape simplex, 1962) <doi:10.1080/00401706.1962.10490033>, the variable shape simplex method of Nelder and Mead (unconstrained optimization with a variable shape simplex made, 1965) <doi:10.1093/comjnl/7.4.308>, and Box's complex method (constrained optimization with a variable shape simplex, 1965) <doi: 10.1093/comjnl/8.1.42>.

Extends the classical Newman studentized range statistic in various ways that can be applied to genome-scale transcriptomic or other expression data.

Computes analytical critical points for nonlinear growth models from known parameter values.

This package provides automated methods for generating initial parameter estimates in population pharmacokinetic modeling. The pipeline integrates adaptive single-point methods, naive pooled graphic approaches, noncompartmental analysis methods, and parameter sweeping across pharmacokinetic models. It estimates residual unexplained variability using either data-driven or fixed-fraction approaches and assigns pragmatic initial values for inter-individual variability. These strategies are designed to improve model robustness and convergence in nlmixr2 workflows. For more details see Huang Z, Fidler M, Lan M, Cheng IL, Kloprogge F, Standing JF (2025) <doi:10.1007/s10928-025-10000-z>.

This package provides methods for Neutrosophic Analysis of Variance (NANOVA) for split-plot and strip-plot experimental designs using interval-valued observations. The package computes neutrosophic sums of squares, mean squares, interval-valued F-statistics, significance tests, and Least Significant Difference (LSD) based multiple comparisons for main plot, sub plot, horizontal factor, vertical factor, and interaction effects. For crisp data, users may provide identical lower and upper response values to obtain results equivalent to classical analysis of variance. The basic idea of neutrosophic statistics is obtained from Smarandache (2014) <https://fs.unm.edu/NeutrosophicStatistics.pdf>, while the analysis procedures implemented in this package are newly developed.

This package implements the nonparametric causality-in-quantiles test (in mean or variance), returning a test object with an S3 plot() method. The current implementation uses one lag of each series (first-order Granger causality setup). Methodology is based on Balcilar, Gupta, and Pierdzioch (2016a) <doi:10.1016/j.resourpol.2016.04.004> and Balcilar et al. (2016) <doi:10.1007/s11079-016-9388-x>.

This package implements the high-dimensional clustering technique Thresholding After Random Projections (n-TARP). Provides functionality to iteratively decompose larger datasets using contextual variables or within-cluster sum of squares. See Tarun & Boutin (2018) <doi:10.48550/arXiv.1806.05297> and Tarun & Boutin (2018) <doi:10.4231/R74B2ZJV> for the original method and applications.