This package provides definitions of core classes and methods used by analytic pipelines that query the OMOP (Observational Medical Outcomes Partnership) common data model.

This package provides details such as Morphine Equivalent Dose (MED), brand name and opioid content which are calculated of all oral opioids authorized for sale by Health Canada and the FDA based on their Drug Identification Number (DIN) or National Drug Code (NDC). MEDs are calculated based on recommendations by Canadian Institute for Health Information (CIHI) and Von Korff et al (2008) and information obtained from Health Canada's Drug Product Database's monthly data dump or FDA Daily database for Canadian and US databases respectively. Please note in no way should output from this package be a substitute for medical advise. All medications should only be consumed on prescription from a licensed healthcare provider.

This package provides a framework for the optimization of breeding programs via optimum contribution selection and mate allocation. An easy to use set of function for computation of optimum contributions of selection candidates, and of the population genetic parameters to be optimized. These parameters can be estimated using pedigree or genotype information, and include kinships, kinships at native haplotype segments, and breed composition of crossbred individuals. They are suitable for managing genetic diversity, removing introgressed genetic material, and accelerating genetic gain. Additionally, functions are provided for computing genetic contributions from ancestors, inbreeding coefficients, the native effective size, the native genome equivalent, pedigree completeness, and for preparing and plotting pedigrees. The methods are described in:\n Wellmann, R., and Pfeiffer, I. (2009) <doi:10.1017/S0016672309000202>.\n Wellmann, R., and Bennewitz, J. (2011) <doi:10.2527/jas.2010-3709>.\n Wellmann, R., Hartwig, S., Bennewitz, J. (2012) <doi:10.1186/1297-9686-44-34>.\n de Cara, M. A. R., Villanueva, B., Toro, M. A., Fernandez, J. (2013) <doi:10.1111/mec.12560>.\n Wellmann, R., Bennewitz, J., Meuwissen, T.H.E. (2014) <doi:10.1017/S0016672314000196>.\n Wellmann, R. (2019) <doi:10.1186/s12859-018-2450-5>.

This package provides functions for detecting outliers in datasets using statistical methods. The package supports identification of anomalous observations in numerical data and is intended for use in data cleaning, exploratory data analysis, and preprocessing workflows.

This package provides tools for easy exploration of the world ocean atlas of the US agency National Oceanic and Atmospheric Administration (NOAA). It includes functions to extract NetCDF data from the repository and code to visualize several physical and chemical parameters of the ocean. A Shiny app further allows interactive exploration of the data. The methods for data collecting and quality checks are described in several papers, which can be found here: <https://www.ncei.noaa.gov/products/world-ocean-atlas>.

Data used in compiling the Handbook of UK Urban Tree Allometric Equations and Size Characteristics (Fennel 2024). The data include measurements of height, crown radius and diameter at breast height (DBH) for UK urban trees. For more details see Fennell (2024) Handbook of UK Urban Tree Allometric Equations and Size Characteristics (Version 1.4). <doi:10.13140/RG.2.2.28745.04961>.

This package provides a method for the quantitative prediction using omics data. This package provides functions to construct the quantitative prediction model using omics data.

The client streamlines access to the services provided by <https://api.openrouteservice.org>. It allows you to painlessly query for directions, isochrones, time-distance matrices, geocoding, elevation, points of interest, and more.

Interface with the One Health VBD (vector-borne disease) Hub <https://vbdhub.org/> and related repositories (VectorByte <https://www.vectorbyte.org>, GBIF <https://www.gbif.org> and AREAdata <https://pearselab.github.io/areadata/>) directly to find, download, and subset vector-borne disease data.

Computes odds ratios and 95% confidence intervals from a generalized linear model object. It also computes model significance with the chi-squared statistic and p-value and it computes model fit using a contingency table to determine the percent of observations for which the model correctly predicts the value of the outcome. Calculates model sensitivity and specificity.

This is a tool to find the optimal rerandomization threshold in non-sequential experiments. We offer three procedures based on assumptions made on the residuals distribution: (1) normality assumed (2) excess kurtosis assumed (3) entire distribution assumed. Illustrations are included. Also included is a routine to unbiasedly estimate Frobenius norms of variance-covariance matrices. Details of the method can be found in "Optimal Rerandomization via a Criterion that Provides Insurance Against Failed Experiments" Adam Kapelner, Abba M. Krieger, Michael Sklar and David Azriel (2020) <arXiv:1905.03337>.

The Open University Learning Analytics Dataset (OULAD) is available from Kuzilek et al. (2017) <doi:10.1038/sdata.2017.171>. The ouladFormat package loads, cleans and formats the OULAD for data analysis (each row of the returned data set is an individual student). The packageâ s main function, combined_dataset(), allows the user to choose whether the returned data set includes assessment, demographics, virtual learning environment (VLE), or registration variables etc.

Calculate ocean wave height summary statistics and process data from bottom-mounted pressure sensor data loggers. Derived primarily from MATLAB functions provided by U. Neumeier at <http://neumeier.perso.ch/matlab/waves.html>. Wave number calculation based on the algorithm in Hunt, J. N. (1979, ISSN:0148-9895) "Direct Solution of Wave Dispersion Equation", American Society of Civil Engineers Journal of the Waterway, Port, Coastal, and Ocean Division, Vol 105, pp 457-459.

An optimized method for distribution-preserving class-proportional down-sampling of bio-medical data.

Construct and evaluate directed tree structures that model the process of occurrence of genetic alterations during carcinogenesis as described in Szabo, A. and Boucher, K (2002) <doi:10.1016/S0025-5564(02)00086-X>.

Design and analysis of confirmatory adaptive clinical trials using the optimal conditional error framework according to Brannath and Bauer (2004) <doi:10.1111/j.0006-341X.2004.00221.x>. An extension to the optimal conditional error function using interim estimates as described in Brannath and Dreher (2024) <doi:10.48550/arXiv.2402.00814> and functions to ensure that the resulting conditional error function is non-increasing are also available.

This package provides a database management tool built as a shiny application. Connect to various databases to send queries, upload files, preview tables, and more.

Build SVG components using element-based functions. With an svg object, we can modify its graphical elements with a suite of transform functions.

Create regression tables for publication. Currently supports lm', glm', survreg', and ivreg outputs.

The supplied code allows for the generation of discrete time series of oscillating species. General shapes can be selected by means of individual functions, which are widely customizable by means of function arguments. All code was developed in the Biological Information Processing Group at the BioQuant Center at Heidelberg University, Germany.

Native R tools for optimal binning workflows in predictive modeling. The package provides APIs for binary, multi-class and continuous targets, with multi-variable binning and scorecard workflows. Methods are informed by Navas-Palencia (2020) <doi:10.48550/arXiv.2001.08025> and Navas-Palencia (2021) <doi:10.48550/arXiv.2104.08619>.

The openFDA API facilitates access to Federal Drug Agency (FDA) data on drugs, devices, foodstuffs, tobacco, and more with httr2'. This package makes the API easily accessible, returning objects which the user can convert to JSON data and parse. Kass-Hout TA, Xu Z, Mohebbi M et al. (2016) <doi:10.1093/jamia/ocv153>.

Seamlessly build and manipulate graph structures, leveraging its high-performance methods for filtering, joining, and mutating data. Ensures that mutations and changes to the graph are performed in place, streamlining your workflow for optimal productivity.

This package provides functions for the design process of survey sampling, with specific tools for multi-wave and multi-phase designs. Perform optimum allocation using Neyman (1934) <doi:10.2307/2342192> or Wright (2012) <doi:10.1080/00031305.2012.733679> allocation, split strata based on quantiles or values of known variables, randomly select samples from strata, allocate sampling waves iteratively, and organize a complex survey design. Also includes a Shiny application for observing the effects of different strata splits. A paper on this package was published in the Journal of Statistical Software <doi:10.18637/jss.v114.i10>.