Design and implementation of Percentile-based Shewhart Control Charts for continuous data. Faraz (2019) <doi:10.1002/qre.2384>.

Density, distribution function, quantile function, and random generation function based on Kittipong Klinjan,Tipat Sottiwan and Sirinapa Aryuyuen (2024)<DOI:10.28919/cmbn/8833>.

Handle data from evolve and resequence experiments. Measured allele frequencies (e.g., from variants called from high-throughput sequencing data) are compared using an update of the PsiSeq algorithm (Earley, Eric and Corbin Jones (2011) <doi:10.1534/genetics.111.129445>). Functions for saving and loading important files are also included, as well as functions for basic data visualization.

This package provides a collection of methods for commonly undertaken analytical tasks, primarily developed for Public Health Scotland (PHS) analysts, but the package is also generally useful to others working in the healthcare space, particularly since it has functions for working with Community Health Index (CHI) numbers. The package can help to make data manipulation and analysis more efficient and reproducible.

This package provides a multiple testing procedure for testing several groups of hypotheses is implemented. Linear dependency among the hypotheses within the same group is modeled by using hidden Markov Models. It is noted that a smaller p value does not necessarily imply more significance due to the dependency. A typical application is to analyze genome wide association studies datasets, where SNPs from the same chromosome are treated as a group and exhibit strong linear genomic dependency. See Wei Z, Sun W, Wang K, Hakonarson H (2009) <doi:10.1093/bioinformatics/btp476> for more details.

Implementation of the Pearson distribution system, including full support for the (d,p,q,r)-family of functions for probability distributions and fitting via method of moments and maximum likelihood method.

This package provides a suite of non-parametric, visual tools for assessing differences in data structures for two datasets that contain different observations of the same variables. These tools are all based on Principal Component Analysis (PCA) and thus effectively address differences in the structures of the covariance matrices of the two datasets. The PCASDC tools consist of easy-to-use, intuitive plots that each focus on different aspects of the PCA decompositions. The cumulative eigenvalue (CE) plot describes differences in the variance components (eigenvalues) of the deconstructed covariance matrices. The angle plot presents the information loss when moving from the PCA decomposition of one dataset to the PCA decomposition of the other. The chroma plot describes the loading patterns of the two datasets, thereby presenting the relative weighting and importance of the variables from the original dataset.

This package provides data sets and functions for exploration of Pakistan Population Census 2023 (<https://www.pbs.gov.pk/>).

This package provides a shiny GUI that performs high dimensional cluster analysis. This tool performs data preparation, clustering and visualisation within a dynamic GUI. With interactive methods allowing the user to change settings all without having to to leave the GUI. An earlier version of this package was described in Laa and Valencia (2022) <doi:10.1140/epjp/s13360-021-02310-1>.

Estimate spatial autoregressive nonlinear probit models with and without autoregressive disturbances using partial maximum likelihood estimation. Estimation and inference regarding marginal effects is also possible. For more details see Bille and Leorato (2020) <doi:10.1080/07474938.2019.1682314>.

Streamlines the steps for adding colour scales and associated legends when working with base R graphics, especially for interactive use. Popular palettes are included and pretty legends produced when mapping a large variety of vector classes to a colour scale. An additional helper for adding axes and grid lines complements the base::plot() work flow.

Calculates an acceptance sampling plan, (sample size and acceptance number) based in MIL STD 105E, Dodge Romig and MIL STD 414 tables and procedures. The arguments for each function are related to lot size, inspection level and quality level. The specific plan operating curve (OC), is calculated by the binomial distribution.

This package provides propensity score weighting methods to control for confounding in causal inference with dichotomous treatments and continuous/binary outcomes. It includes the following functional modules: (1) visualization of the propensity score distribution in both treatment groups with mirror histogram, (2) covariate balance diagnosis, (3) propensity score model specification test, (4) weighted estimation of treatment effect, and (5) augmented estimation of treatment effect with outcome regression. The weighting methods include the inverse probability weight (IPW) for estimating the average treatment effect (ATE), the IPW for average treatment effect of the treated (ATT), the IPW for the average treatment effect of the controls (ATC), the matching weight (MW), the overlap weight (OVERLAP), and the trapezoidal weight (TRAPEZOIDAL). Sandwich variance estimation is provided to adjust for the sampling variability of the estimated propensity score. These methods are discussed by Hirano et al (2003) <DOI:10.1111/1468-0262.00442>, Lunceford and Davidian (2004) <DOI:10.1002/sim.1903>, Li and Greene (2013) <DOI:10.1515/ijb-2012-0030>, and Li et al (2016) <DOI:10.1080/01621459.2016.1260466>.

Includes functions implementing the conditionally optimal matching algorithm, which can be used to generate matched samples in designs with multiple groups. The algorithm is described in Nattino, Song and Lu (2022) <doi:10.1016/j.csda.2021.107364>.

Hybridization probes for target sequences can be made based on melting temperature value calculated by R package TmCalculator <https://CRAN.R-project.org/package=TmCalculator> and methods extended from Beliveau, B. J.,(2018) <doi:10.1073/pnas.1714530115>, and those hybridization probes can be used to capture specific target regions in fluorescence in situ hybridization and next generation sequence experiments.

This version of the permutational algorithm generates a dataset in which event and censoring times are conditional on an user-specified list of covariates, some or all of which are time-dependent.

An embedded proximal interior point quadratic programming solver, which can solve dense and sparse quadratic programs, described in Schwan, Jiang, Kuhn, and Jones (2023) <doi:10.48550/arXiv.2304.00290>. Combining an infeasible interior point method with the proximal method of multipliers, the algorithm can handle ill-conditioned convex quadratic programming problems without the need for linear independence of the constraints. The solver is written in header only C++ 14 leveraging the Eigen library for vectorized linear algebra. For small dense problems, vectorized instructions and cache locality can be exploited more efficiently. Allocation free problem updates and re-solves are also provided.

Can be used to carry out permutation based gene expression pathway analysis. This work was supported by a National Institute of Allergy and Infectious Disease/National Institutes of Health contract (No. HHSN272200900059C).

Estimates (and controls for) phylogenetic signal through phylogenetic eigenvectors regression (PVR) and phylogenetic signal-representation (PSR) curve, along with some plot utilities.

Create, transform, and summarize custom random variables with distribution functions (analogues of p*()', d*()', q*()', and r*() functions from base R). Two types of distributions are supported: "discrete" (random variable has finite number of output values) and "continuous" (infinite number of values in the form of continuous random variable). Functions for distribution transformations and summaries are available. Implemented approaches often emphasize approximate and numerical solutions: all distributions assume finite support and finite values of density function; some methods implemented with simulation techniques.

Download and generate summaries for the rodent, plant, ant, and weather data from the Portal Project. Portal is a long-term (and ongoing) experimental monitoring site in the Chihuahuan desert. The raw data files can be found at <https://github.com/weecology/portaldata>.

Jointly segment several ChIP-seq samples to find the peaks which are the same and different across samples. The fast approximate maximum Poisson likelihood algorithm is described in "PeakSegJoint: fast supervised peak detection via joint segmentation of multiple count data samples" <doi:10.48550/arXiv.1506.01286> by TD Hocking and G Bourque.

Weighted Deming regression, also known as errors-in-variable regression, is applied with suitable weights. Weights are modeled via a precision profile; thus the methods implemented here are referred to as precision profile weighted Deming (PWD) regression. The package covers two settings â one where the precision profiles are known either from external studies or from adequate replication of the X and Y readings, and one in which there is a plausible functional form for the precision profiles but the exact (unknown) function must be estimated from the (generally singlicate) readings. The function set includes tools for: estimated standard errors (via jackknifing); standardized-residual analysis function with regression diagnostic tools for normality, linearity and constant variance; and an outlier analysis identifying significant outliers for closer investigation. The following reference provides further information on mathematical derivations and applications. Hawkins, D.M., and J.J. Kraker (2026). Precision Profile Weighted Deming Regression for Methods Comparison'. The Journal of Applied Laboratory Medicine 11, 379-392 <doi:10.1093/jalm/jfaf183>.

Various functions for computing pseudo-observations for censored data regression. Computes pseudo-observations for modeling: competing risks based on the cumulative incidence function, survival function based on the restricted mean, survival function based on the Kaplan-Meier estimator see Klein et al. (2008) <doi:10.1016/j.cmpb.2007.11.017>.