Utilities for the Pareto, piecewise Pareto and generalized Pareto distribution that are useful for reinsurance pricing. In particular, the package provides a non-trivial algorithm that can be used to match the expected losses of a tower of reinsurance layers with a layer-independent collective risk model. The theoretical background of the matching algorithm and most other methods are described in Ulrich Riegel (2018) <doi:10.1007/s13385-018-0177-3>.

Gene-level variant association tests with disease status for pedigree data: kernel and burden association statistics.

Matches cases to controls based on genotype principal components (PC). In order to produce better results, matches are based on the weighted distance of PCs where the weights are equal to the % variance explained by that PC. A weighted Mahalanobis distance metric (Kidd et al. (1987) <DOI:10.1016/0031-3203(87)90066-5>) is used to determine matches.

Aims at detecting single nucleotide variation (SNV) and insertion/deletion (INDEL) in circulating tumor DNA (ctDNA), used as a surrogate marker for tumor, at each base position of an Next Generation Sequencing (NGS) analysis. Mutations are assessed by comparing the minor-allele frequency at each position to the measured PER in control samples.

Estimates when and where a model-guided treatment strategy may outperform a treat-all or treat-none approach by Monte Carlo simulation and evaluation of the Net Monetary Benefit. Details can be viewed in Parsons et al. (2023) <doi:10.21105/joss.05328>.

This package provides a multiway method to decompose a tensor (array) of any order, as a generalisation of SVD also supporting non-identity metrics and penalisations. 2-way SVD with these extensions is also available. The package includes also some other multiway methods: PCAn (Tucker-n) and PARAFAC/CANDECOMP with these extensions.

The rgl implementation of plot3D functions.

This package provides functions for causal structure learning and causal inference using graphical models. The main algorithms for causal structure learning are PC (for observational data without hidden variables), FCI and RFCI (for observational data with hidden variables), and GIES (for a mix of data from observational studies (i.e. observational data) and data from experiments involving interventions (i.e. interventional data) without hidden variables). For causal inference the IDA algorithm, the Generalized Backdoor Criterion (GBC), the Generalized Adjustment Criterion (GAC) and some related functions are implemented. Functions for incorporating background knowledge are provided.

Set of functions to polish content for Microsoft Word and PowerPoint into OOXML'. Polishing is the conversion of the R object into an OOXML representation of the object that can then be added to Word or PowerPoint files.

Identifies reference periods (months, fortnights, and weeks) in Brazil's quarterly PNADC (Pesquisa Nacional por Amostra de Domicilios Continua) survey data and computes calibrated weights for sub-quarterly analysis. The core algorithm uses IBGE (Instituto Brasileiro de Geografia e Estatistica) Parada Tecnica (technical break) rules combined with respondent birthdates to determine which temporal period each survey observation refers to. Period identification follows a nested hierarchy enforced by construction: fortnights require months, weeks require fortnights. Achieves approximately 97% monthly determination rate with the full series (2012-2025). Strict fortnight and week rates are approximately 9% and 3% respectively, as they cannot leverage cross-quarter panel aggregation. Experimental strategies (probabilistic assignment and UPA (Primary Sampling Unit) aggregation) further improve these determination rates. The package provides adaptive hierarchical weight calibration (4/2/1 cell levels for month/fortnight/week) with period-specific smoothing to produce survey weights calibrated to SIDRA (Sistema IBGE de Recuperacao Automatica) population totals. Also includes a SIDRA mensalization module that converts 86+ official rolling quarter series from the IBGE SIDRA API (Application Programming Interface) into exact monthly estimates, without requiring access to microdata. Hecksher (2020) <https://repositorio.ipea.gov.br/handle/11058/9859>.

Analyses and reports questionnaire and experiment data exported from PsyToolkit'. The package reads downloaded study folders, parses questionnaire structure, optionally merges demographic exports from CloudResearch or Prolific, and produces summary overviews of responses and completion times. It also provides helper functions to extract and aggregate experiment measures and survey variables, and to export results to spreadsheet files for further analysis and archiving. See Stoet (2017) <doi:10.1177/0098628316677643> for the PsyToolkit platform.

This package provides a power analysis tool for jointly testing the cause-1 cause-specific hazard and the any-cause hazard with competing risks data.

This package implements the Penalized Youden Index Estimator (PYE) and the Covariate-Adjusted Youden Index Estimator (covYI), providing a novel framework for feature and covariate selection and combination in high-dimensional binary classification problems. Methodologies are based on Salaroli and Pardo (2023) <doi:10.1016/j.chemolab.2023.104786> and an unpublished manuscript by Salaroli and Pardo (2026) under review.

Quantitative trait loci (QTL) analysis and exploration of meiotic patterns in autopolyploid bi-parental F1 populations. For all ploidy levels, identity-by-descent (IBD) probabilities can be estimated. Significance thresholds, exploring QTL allele effects and visualising results are provided. For more background and to reference the package see <doi:10.1093/bioinformatics/btab574>.

This package implements the algorithm of Christensen (2024) <doi:10.1214/22-BA1353> for estimating marginal likelihoods via permutation counting.

This package provides a coding assistant using Perplexity's Large Language Models <https://www.perplexity.ai/> API. A set of functions and RStudio add-ins that aim to help R developers.

An implementation of a hybrid method of person-oriented method and perturbation on the model. Pompom is the initials of the two methods. The hybrid method will provide a multivariate intraindividual variability metric (iRAM). The person-oriented method used in this package refers to uSEM (unified structural equation modeling, see Kim et al., 2007, Gates et al., 2010 and Gates et al., 2012 for details). Perturbation on the model was conducted according to impulse response analysis introduced in Lutkepohl (2007). Kim, J., Zhu, W., Chang, L., Bentler, P. M., & Ernst, T. (2007) <doi:10.1002/hbm.20259>. Gates, K. M., Molenaar, P. C. M., Hillary, F. G., Ram, N., & Rovine, M. J. (2010) <doi:10.1016/j.neuroimage.2009.12.117>. Gates, K. M., & Molenaar, P. C. M. (2012) <doi:10.1016/j.neuroimage.2012.06.026>. Lutkepohl, H. (2007, ISBN:3540262393).

Datetimes and timestamps are invariably an imprecise notation, with any partial representation implying some amount of uncertainty. To handle this, parttime provides classes for embedding partial missingness as a central part of its datetime classes. This central feature allows for more ergonomic use of datetimes for challenging datetime computation, including calculations of overlapping date ranges, imputations, and more thoughtful handling of ambiguity that arises from uncertain time zones. This package was developed first and foremost with pharmaceutical applications in mind, but aims to be agnostic to application to accommodate general use cases just as conveniently.

This package provides a set of Analysis Data Model (ADaM) datasets constructed by modifying the ADaM datasets in the pharmaverseadam package to meet J&J Innovative Medicine's standard data structure for Clinical and Statistical Programming.

It enables sparklyr to integrate with Spark Connect', and Databricks Connect by providing a wrapper over the PySpark python library.

Provision of a set of models and methods for use in the allocation and management of capital in financial portfolios.

This package implements the pcgen algorithm, which is a modified version of the standard pc-algorithm, with specific conditional independence tests and modified orientation rules. pcgen extends the approach of Valente et al. (2010) <doi:10.1534/genetics.109.112979> with reconstruction of direct genetic effects.

This package provides tools for downloading, reading and analyzing the Continuous National Household Sample Survey - PNADC, a household survey from Brazilian Institute of Geography and Statistics - IBGE. The data must be downloaded from the official website <https://www.ibge.gov.br/>. Further analysis must be made using package survey'.

This is a computational package designed to identify the most sensitive interactions within a network which must be estimated most accurately in order to produce qualitatively robust predictions to a press perturbation. This is accomplished by enumerating the number of sign switches (and their magnitude) in the net effects matrix when an edge experiences uncertainty. The package produces data and visualizations when uncertainty is associated to one or more edges in the network and according to a variety of distributions. The software requires the network to be described by a system of differential equations but only requires as input a numerical Jacobian matrix evaluated at an equilibrium point. This package is based on Koslicki, D., & Novak, M. (2017) <doi:10.1007/s00285-017-1163-0>.