An implementation of interpreted string literals. Based on the glue package by Hester & Bryan (2024) <doi:10.32614/CRAN.package.glue> but with a focus on efficiency and simplicity at a cost of flexibility.

Last.fm'<https://www.last.fm> is a music platform focussed on building a detailed profile of a users listening habits. It does this by scrobbling (recording) every track you listen to on other platforms ('spotify', youtube', soundcloud etc) and transferring them to your Last.fm database. This allows Last.fm to act as a complete record of your entire listening history. scrobbler provides helper functions to download and analyse your listening history in R.

The functions sp() and sp_seq() compute the support points in Mak and Joseph (2018) <DOI:10.1214/17-AOS1629>. Support points can be used as a representative sample of a desired distribution, or a representative reduction of a big dataset (e.g., an "optimal" thinning of Markov-chain Monte Carlo sample chains). This work was supported by USARO grant W911NF-14-1-0024 and NSF DMS grant 1712642.

Simulate survival times from standard parametric survival distributions (exponential, Weibull, Gompertz), 2-component mixture distributions, or a user-defined hazard, log hazard, cumulative hazard, or log cumulative hazard function. Baseline covariates can be included under a proportional hazards assumption. Time dependent effects (i.e. non-proportional hazards) can be included by interacting covariates with linear time or a user-defined function of time. Clustered event times are also accommodated. The 2-component mixture distributions can allow for a variety of flexible baseline hazard functions reflecting those seen in practice. If the user wishes to provide a user-defined hazard or log hazard function then this is possible, and the resulting cumulative hazard function does not need to have a closed-form solution. For details see the supporting paper <doi:10.18637/jss.v097.i03>. Note that this package is modelled on the survsim package available in the Stata software (see Crowther and Lambert (2012) <https://www.stata-journal.com/sjpdf.html?articlenum=st0275> or Crowther and Lambert (2013) <doi:10.1002/sim.5823>).

This package provides functionality to fit and simulate from stationary vine copula models for time series, see Nagler et al. (2022) <doi:10.1016/j.jeconom.2021.11.015>.

This package provides wrappers for common activity patterns in simmer trajectories.

This package implements methods for obtaining kernel density estimates subject to a variety of shape constraints (unimodality, bimodality, symmetry, tail monotonicity, bounds, and constraints on the number of inflection points). Enforcing constraints can eliminate unwanted waves or kinks in the estimate, which improves its subjective appearance and can also improve statistical performance. The main function scdensity() is very similar to the density() function in stats', allowing shape-restricted estimates to be obtained with little effort. The methods implemented in this package are described in Wolters and Braun (2017) <doi:10.1080/03610918.2017.1288247>, Wolters (2012) <doi:10.18637/jss.v047.i06>, and Hall and Huang (2002) <https://www3.stat.sinica.edu.tw/statistica/j12n4/j12n41/j12n41.htm>. See the scdensity() help for for full citations.

This package provides significance controlled variable selection algorithms with different directions (forward, backward, stepwise) based on diverse criteria (AIC, BIC, adjusted r-square, PRESS, or p-value). The algorithm selects a final model with only significant variables defined as those with significant p-values after multiple testing correction such as Bonferroni, False Discovery Rate, etc. See Zambom and Kim (2018) <doi:10.1002/sta4.210>.

Cluster-independent method based on topology structure of gene co-expression network for identifying feature gene sets, extracting cellular subpopulations, and elucidating intrinsic relationships among these subpopulations. Without prior cell clustering, SifiNet circumvents potential inaccuracies in clustering that may influence subsequent analyses. This method is introduced in Qi Gao, Zhicheng Ji, Liuyang Wang, Kouros Owzar, Qi-Jing Li, Cliburn Chan, Jichun Xie "SifiNet: a robust and accurate method to identify feature gene sets and annotate cells" (2024) <doi:10.1093/nar/gkae307>.

This package provides tools for the optimization of stratified sampling design. It determines a stratification of a sampling frame that minimizes sample cost while satisfying precision constraints in a multivariate and multidomain context. The approach relies on a genetic algorithm; each candidate partition of the frame is an individual whose fitness is evaluated via the Bethel-Chromy allocation to meet target precisions. Functions support analysis of optimization results, labeling of the frame with new strata, and drawing a sample according to the optimal allocation. Algorithmic components adapt code from the genalg package. See M. Ballin and G. Barcaroli (2020) "R package SamplingStrata: new developments and extension to Spatial Sampling" <doi:10.48550/arXiv.2004.09366>.

Generalized additive models under shape constraints on the component functions of the linear predictor. Models can include multiple shape-constrained (univariate and bivariate) and unconstrained terms. Routines of the package mgcv are used to set up the model matrix, print, and plot the results. Multiple smoothing parameter estimation by the Generalized Cross Validation or similar. See Pya and Wood (2015) <doi:10.1007/s11222-013-9448-7> for an overview. A broad selection of shape-constrained smoothers, linear functionals of smooths with shape constraints, and Gaussian models with AR1 residuals.

R implementation of S. Joe and F. Y. Kuo (2008) <DOI:10.1137/070709359>. The implementation is based on the data file new-joe-kuo-6.21201 <http://web.maths.unsw.edu.au/~fkuo/sobol/>.

Collection of shiny application styling that are the based on the GOV.UK Design System. See <https://design-system.service.gov.uk/components/> for details.

Enables deploying configuration file-based shiny apps with minimal programming for interactive exploration and analysis showcase of molecular expression data. For exploration, supports visualization of correlations between rows of an expression matrix and a table of observations, such as clinical measures, and comparison of changes in expression over time. For showcase, enables visualizing the results of differential expression from package such as limma', co-expression modules from WGCNA and lower dimensional projections.

This package contains a suite of functions for survival analysis in health economics. These can be used to run survival models under a frequentist (based on maximum likelihood) or a Bayesian approach (both based on Integrated Nested Laplace Approximation or Hamiltonian Monte Carlo). To run the Bayesian models, the user needs to install additional modules (packages), i.e. survHEinla and survHEhmc'. These can be installed from <https://giabaio.r-universe.dev/> using install.packages("survHEhmc", repos = c("https://giabaio.r-universe.dev", "https://cloud.r-project.org")) and install.packages("survHEinla", repos = c("https://giabaio.r-universe.dev", "https://cloud.r-project.org")) respectively. survHEinla is based on the package INLA, which is available for download at <https://inla.r-inla-download.org/R/stable/>. The user can specify a set of parametric models using a common notation and select the preferred mode of inference. The results can also be post-processed to produce probabilistic sensitivity analysis and can be used to export the output to an Excel file (e.g. for a Markov model, as often done by modellers and practitioners). <doi:10.18637/jss.v095.i14>.

This package implements estimators for structured covariance matrices in the presence of pairwise and spatial covariates. Metodiev, Perrot-Dockès, Ouadah, Fosdick, Robin, Latouche & Raftery (2025) <doi:10.48550/arXiv.2411.04520>.

Estimates a covariance matrix using Stein's isotonized covariance estimator, or a related estimator suggested by Haff.

This package provides tools which allow regression variables to be placed on similar scales, offering computational benefits as well as easing interpretation of regression output.

Simple utilities to design and generate density functions on bounded regions in space and space-time, and simulate independent, identically distributed data therefrom. See Davies & Lawson (2019) <doi:10.1080/00949655.2019.1575066> for example.

This package implements the routines and algorithms developed and analysed in "Multiple Systems Estimation for Sparse Capture Data: Inferential Challenges when there are Non-Overlapping Lists" Chan, L, Silverman, B. W., Vincent, K (2019) <arXiv:1902.05156>. This package explicitly handles situations where there are pairs of lists which have no observed individuals in common. It deals correctly with parameters whose estimated values can be considered as being negative infinity. It also addresses other possible issues of non-existence and non-identifiability of maximum likelihood estimates.

This package provides an easy-to-use module for adding a chat to a Shiny app. Allows users to send messages and view messages from other users. Messages can be stored in a database or a .rds file.

This package implements the algorithm described in Guo, H., and Li, J., "scSorter: assigning cells to known cell types according to known marker genes". Cluster cells to known cell types based on marker genes specified for each cell type.

Translates antibody levels measured in cross-sectional population samples into estimates of the frequency with which seroconversions (infections) occur in the sampled populations. Replaces the previous `seroincidence` package.

This package provides tools for analyzing spatial cell-cell interactions based on ligand-receptor pairs, including functions for local, regional, and global analysis using spatial transcriptomics data. Integrates with databases like CellChat <http://www.cellchat.org/>, CellPhoneDB <https://www.cellphonedb.org/>, Cellinker <https://www.rna-society.org/cellinker/index.html>, ICELLNET <https://github.com/soumelis-lab/ICELLNET>, and ConnectomeDB <https://humanconnectome.org/software/connectomedb/> to identify ligand-receptor pairs, visualize interactions through heatmaps, chord diagrams, and infer interactions on different spatial scales.