Holds functions developed by the University of Ottawa's SAiVE (Spatio-temporal Analysis of isotope Variations in the Environment) research group with the intention of facilitating the re-use of code, foster good code writing practices, and to allow others to benefit from the work done by the SAiVE group. Contributions are welcome via the GitHub repository <https://github.com/UO-SAiVE/SAiVE> by group members as well as non-members.

Synthesize numeric, categorical, mixed and time series data. Data circumstances including mixed (or zero-inflated) distributions and missing data patterns are reproduced in the synthetic data. A single parameter allows balancing between high-quality synthetic data that represents correlations of the original data and lower quality but more privacy safe synthetic data without correlations. Tuning can be done per variable or for the whole dataset.

SMAHP (pronounced as SOO-MAP) is a novel multi-omics framework for causal mediation analysis of high-dimensional proteogenomic data with survival outcomes. The full methodological details can be found in our recent preprint by Ahn S et al. (2025) <doi:10.48550/arXiv.2503.08606>.

It is a toolbox for Sequential Probability Ratio Tests (SPRT), Wald (1945) <doi:10.2134/agronj1947.00021962003900070011x>. SPRTs are applied to the data during the sampling process, ideally after each observation. At any stage, the test will return a decision to either continue sampling or terminate and accept one of the specified hypotheses. The seq_ttest() function performs one-sample, two-sample, and paired t-tests for testing one- and two-sided hypotheses (Schnuerch & Erdfelder (2019) <doi:10.1037/met0000234>). The seq_anova() function allows to perform a sequential one-way fixed effects ANOVA (Steinhilber et al. (2023) <doi:10.31234/osf.io/m64ne>). Learn more about the package by using vignettes "browseVignettes(package = "sprtt")" or go to the website <https://meikesteinhilber.github.io/sprtt/>.

Contemporary software commonly used to design stated preference experiments are expensive and the code is closed source. This is a free software package with an easy to use interface to make flexible stated preference experimental designs using state-of-the-art methods. For an overview of stated choice experimental design theory, see e.g., Rose, J. M. & Bliemer, M. C. J. (2014) in Hess S. & Daly. A. <doi:10.4337/9781781003152>. The package website can be accessed at <https://spdesign.edsandorf.me>. We acknowledge funding from the European Unionâ s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant INSPiRE (Grant agreement ID: 793163).

Fit Hawkes and log-Gaussian Cox process models with extensions. Introduced in Hawkes (1971) <doi:10.2307/2334319> a Hawkes process is a self-exciting temporal point process where the occurrence of an event immediately increases the chance of another. We extend this to consider self-inhibiting process and a non-homogeneous background rate. A log-Gaussian Cox process is a Poisson point process where the log-intensity is given by a Gaussian random field. We extend this to a joint likelihood formulation fitting a marked log-Gaussian Cox model. In addition, the package offers functionality to fit self-exciting spatiotemporal point processes. Models are fitted via maximum likelihood using TMB (Template Model Builder). Where included 1) random fields are assumed to be Gaussian and are integrated over using the Laplace approximation and 2) a stochastic partial differential equation model, introduced by Lindgren, Rue, and Lindström. (2011) <doi:10.1111/j.1467-9868.2011.00777.x>, is defined for the field(s).

This package provides tools to design experiments, compute Sobol sensitivity indices, and summarise stochastic responses inspired by the strategy described by Zhu and Sudret (2021) <doi:10.1016/j.ress.2021.107815>. Includes helpers to optimise toy models implemented in C++, visualise indices with uncertainty quantification, and derive reliability-oriented sensitivity measures based on failure probabilities. It is further detailed in Logosha, Maumy and Bertrand (2022) <doi:10.1063/5.0246026> and (2023) <doi:10.1063/5.0246024> or in Bertrand, Logosha and Maumy (2024) <https://hal.science/hal-05371803>, <https://hal.science/hal-05371795> and <https://hal.science/hal-05371798>.

Add significance marks to any R Boxplot, including a given significance niveau.

Processes amino acid alignments produced by the IPD-IMGT/HLA (Immuno Polymorphism-ImMunoGeneTics/Human Leukocyte Antigen) Database to identify user-defined amino acid residue motifs shared across HLA alleles, HLA alleles, or HLA haplotypes, and calculates frequencies based on HLA allele frequency data. SSHAARP (Searching Shared HLA Amino Acid Residue Prevalence) uses Generic Mapping Tools (GMT) software and the GMT R package to generate global frequency heat maps that illustrate the distribution of each user-defined map around the globe. SSHAARP analyzes the allele frequency data described by Solberg et al. (2008) <doi:10.1016/j.humimm.2008.05.001>, a global set of 497 population samples from 185 published datasets, representing 66,800 individuals total. Users may also specify their own datasets, but file conventions must follow the prebundled Solberg dataset, or the mock haplotype dataset.

Selection index is one of the efficient and acurrate method for selection of animals. This package is useful for construction of selection indices. It uses mixed and random model least squares analysis to estimate the heritability of traits and genetic correlation between traits. The package uses the sire model as it is considered as random effect. The genetic and phenotypic (co)variances along with the relative economic values are used to construct the selection index for any number of traits. It also estimates the accuracy of the index and the genetic gain expected for different traits. Fisher (1936) <doi:10.1111/j.1469-1809.1936.tb02137.x>.

This package provides a process-oriented and trajectory-based Discrete-Event Simulation (DES) package for R. It is designed as a generic yet powerful framework. The architecture encloses a robust and fast simulation core written in C++ with automatic monitoring capabilities. It provides a rich and flexible R API that revolves around the concept of trajectory, a common path in the simulation model for entities of the same type. Documentation about simmer is provided by several vignettes included in this package, via the paper by Ucar, Smeets & Azcorra (2019, <doi:10.18637/jss.v090.i02>), and the paper by Ucar, Hernández, Serrano & Azcorra (2018, <doi:10.1109/MCOM.2018.1700960>); see citation("simmer") for details.

Fast, wavelet-based Empirical Bayes shrinkage methods for signal denoising, including smoothing Poisson-distributed data and Gaussian-distributed data with possibly heteroskedastic error. The algorithms implement the methods described Z. Xing, P. Carbonetto & M. Stephens (2021) <https://jmlr.org/papers/v22/19-042.html>.

Data and functions to support Bayesian and frequentist inference and decision making for the Coursera Specialization "Statistics with R". See <https://github.com/StatsWithR/statsr> for more information.

This package implements survival-model-based imputation for censored laboratory measurements, including Tobit-type models with several distribution options. Suitable for data with values below detection or quantification limits, the package identifies the best-fitting distribution and produces realistic imputations that respect the censoring thresholds.

Permits determination of a set of optimal dynamic treatment regimes and sample size for a SMART design in the Bayesian setting with binary outcomes. Please see Artman (2020) <arXiv:2008.02341>.

Makes it possible to serve map tiles for web maps (e.g. leaflet) based on a function or a stars object without having to render them in advance. This enables parallelization of the rendering, separating the data source and visualization location and to provide web services.

Chooses subgroup specific optimal doses in a phase I dose finding clinical trial allowing for subgroup combination and simulates clinical trials under the subgroup specific time to event continual reassessment method. Chapple, A.G., Thall, P.F. (2018) <doi:10.1002/pst.1891>.

Send email using Sendgrid <https://sendgrid.com/> mail API(v3) <https://docs.sendgrid.com/api-reference/how-to-use-the-sendgrid-v3-api/authentication>.

Perform sensitivity analysis in structural equation modeling using meta-heuristic optimization methods (e.g., ant colony optimization and others). The references for the proposed methods are: (1) Leite, W., & Shen, Z., Marcoulides, K., Fish, C., & Harring, J. (2022). <doi:10.1080/10705511.2021.1881786> (2) Harring, J. R., McNeish, D. M., & Hancock, G. R. (2017) <doi:10.1080/10705511.2018.1506925>; (3) Fisk, C., Harring, J., Shen, Z., Leite, W., Suen, K., & Marcoulides, K. (2022). <doi:10.1177/00131644211073121>; (4) Socha, K., & Dorigo, M. (2008) <doi:10.1016/j.ejor.2006.06.046>. We also thank Dr. Krzysztof Socha for sharing his research on ant colony optimization algorithm with continuous domains and associated R code, which provided the base for the development of this package.

R bindings to SVD and eigensolvers (PROPACK, nuTRLan).

This is the implementation of the novel structural Bayesian information criterion by Zhou, 2020 (under review). In this method, the prior structure is modeled and incorporated into the Bayesian information criterion framework. Additionally, we also provide the implementation of a two-step algorithm to generate the candidate model pool.

Copula based Cox proportional hazards models for survival data subject to dependent censoring. This approach does not assume that the parameter defining the copula is known. The dependency parameter is estimated with other finite model parameters by maximizing a Pseudo likelihood function. The cumulative hazard function is estimated via estimating equations derived based on martingale ideas. Available copula functions include Frank, Gumbel and Normal copulas. Only Weibull and lognormal models are allowed for the censoring model, even though any parametric model that satisfies certain identifiability conditions could be used. Implemented methods are described in the article "Copula based Cox proportional hazards models for dependent censoring" by Deresa and Van Keilegom (2024) <doi:10.1080/01621459.2022.2161387>.

Process and summarize DAS data files. These files are typically, but do not have to be DAS <https://swfsc-publications.fisheries.noaa.gov/publications/TM/SWFSC/NOAA-TM-NMFS-SWFSC-305.PDF> data produced by the Southwest Fisheries Science Center (SWFSC) program WinCruz'. This package standardizes and streamlines basic DAS data processing, and includes a PDF with the DAS data format requirements expected by the package.

Explains the behavior of a time series by decomposing it into its trend, seasonality and residuals. It is built to perform very well in the presence of significant level shifts. It is designed to play well with any breakpoint algorithm and any smoothing algorithm. Currently defaults to lowess for smoothing and strucchange for breakpoint identification. The package is useful in areas such as trend analysis, time series decomposition, breakpoint identification and anomaly detection.