Simultaneous tests and confidence intervals are provided for one-way experimental designs with one or many normally distributed, primary response variables (endpoints). Differences (Hasler and Hothorn, 2011 <doi:10.2202/1557-4679.1258>) or ratios (Hasler and Hothorn, 2012 <doi:10.1080/19466315.2011.633868>) of means can be considered. Various contrasts can be chosen, unbalanced sample sizes are allowed as well as heterogeneous variances (Hasler and Hothorn, 2008 <doi:10.1002/bimj.200710466>) or covariance matrices (Hasler, 2014 <doi:10.1515/ijb-2012-0015>).

It offers functions for creating dashboard with Fomantic UI.

Scripts and exercises that use card shuffling to teach confidence interval comparisons for different estimators.

This package provides computational tools for estimating inverse regions and constructing the corresponding simultaneous outer and inner confidence regions. Acceptable input includes both one-dimensional and two-dimensional data for linear, logistic, functional, and spatial generalized least squares regression models. Functions are also available for constructing simultaneous confidence bands (SCBs) for these models. The definition of simultaneous confidence regions (SCRs) follows Sommerfeld et al. (2018) <doi:10.1080/01621459.2017.1341838>. Methods for estimating inverse regions, SCRs, and the nonparametric bootstrap are based on Ren et al. (2024) <doi:10.1093/jrsssc/qlae027>. Methods for constructing SCBs are described in Crainiceanu et al. (2024) <doi:10.1201/9781003278726> and Telschow et al. (2022) <doi:10.1016/j.jspi.2021.05.008>.

Estimates correlation coefficients with associated confidence limits for bivariate, partially censored survival times. Uses the iterative multiple imputation approach proposed by Schemper, Kaider, Wakounig and Heinze (2013) <doi:10.1002/sim.5874>. Provides a scatterplot function to visualize the bivariate distribution, either on the original time scale or as copula.

The implementation to perform the geometric spatial point analysis developed in Hernández & Solàs (2022) <doi:10.1007/s00180-022-01244-1>. It estimates the geometric goodness-of-fit index for a set of variables against a response one based on the sf package. The package has methods to print and plot the results.

This package provides a set of functions is provided for 1) the stratum lengths analysis along a chosen direction, 2) fast estimation of continuous lag spatial Markov chains model parameters and probability computing (also for large data sets), 3) transition probability maps and transiograms drawing, 4) simulation methods for categorical random fields. More details on the methodology are discussed in Sartore (2013) <doi:10.32614/RJ-2013-022> and Sartore et al. (2016) <doi:10.1016/j.cageo.2016.06.001>.

This package implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.

High dimensional survival data analysis with Markov Chain Monte Carlo(MCMC). Currently supports frailty data analysis. Allows for Weibull and Exponential distribution. Includes function for interval censored data.

Scale invariant version of the original PNN proposed by Specht (1990) <doi:10.1016/0893-6080(90)90049-q> with the added functionality of allowing for smoothing along multiple dimensions while accounting for covariances within the data set. It is written in the R statistical programming language. Given a data set with categorical variables, we use this algorithm to estimate the probabilities of a new observation vector belonging to a specific category. This type of neural network provides the benefits of fast training time relative to backpropagation and statistical generalization with only a small set of known observations.

Collect your data on digital marketing campaigns from Shopify Ads using the Windsor.ai API <https://windsor.ai/api-fields/>.

This package provides several datasets useful for processing and analysis of text in Turkish from an online shopping platform.

This package provides a set of Rmarkdown themes for creating scientific and professional documents. Simple interface with features to ease navigation across the page and sub-pages.

Maximum-likelihood estimation of the spatial autoregressive stochastic frontier model with individual fixed effects (removed by first differencing) and endogenous regressors handled through a Gaussian control function, as in Giannini (2025) <doi:10.1080/17421772.2024.2414962>. Returns coefficient estimates and standard errors, spatially-corrected technical (in)efficiency scores, and direct, indirect and total marginal impacts. Depends only on base R.

Turns remote file URLs into paths to durable managed local copies stored in a fixed subdirectory of platform-appropriate, package-specific user data directories. Matching copies are reused across R sessions and remain available for offline use. Supports optional ETag-based versions, content validation, and staged replacement that prevents failed downloads and files that fail a supplied validator from becoming managed local copies. Includes tools to inspect, conservatively prune, and explicitly remove retained copies.

Computes the optimal sample size for various 2-group designs (e.g., when comparing the means of two groups assuming equal variances, unequal variances, or comparing proportions) when the aim is to maximize the rewards over the full decision procedure of a) running a trial (with the computed sample size), and b) subsequently administering the winning treatment to the remaining N-n units in the population. Sample sizes and expected rewards for standard t- and z- tests are also provided.

Modeling spatial dependencies in dependent variables, extending traditional spatial regression approaches. It allows for the joint modeling of both the mean and the variance of the dependent variable, incorporating semiparametric effects in both models. Based on generalized additive models (GAM), the package enables the inclusion of non-parametric terms while maintaining the classical theoretical framework of spatial regression. Additionally, it implements the Generalized Spatial Autoregression (GSAR) model, which extends classical methods like logistic Spatial Autoregresive Models (SAR), probit Spatial Autoregresive Models (SAR), and Poisson Spatial Autoregresive Models (SAR), offering greater flexibility in modeling spatial dependencies and significantly improving computational efficiency and the statistical properties of the estimators. Related work includes: a) J.D. Toloza-Delgado, Melo O.O., Cruz N.A. (2024). "Joint spatial modeling of mean and non-homogeneous variance combining semiparametric SAR and GAMLSS models for hedonic prices". <doi:10.1016/j.spasta.2024.100864>. b) Cruz, N. A., Toloza-Delgado, J. D., Melo, O. O. (2024). "Generalized spatial autoregressive model". <doi:10.48550/arXiv.2412.00945>.

We develop a novel matrix factorization tool named scINSIGHT to jointly analyze multiple single-cell gene expression samples from biologically heterogeneous sources, such as different disease phases, treatment groups, or developmental stages. Given multiple gene expression samples from different biological conditions, scINSIGHT simultaneously identifies common and condition-specific gene modules and quantify their expression levels in each sample in a lower-dimensional space. With the factorized results, the inferred expression levels and memberships of common gene modules can be used to cluster cells and detect cell identities, and the condition-specific gene modules can help compare functional differences in transcriptomes from distinct conditions. Please also see Qian K, Fu SW, Li HW, Li WV (2022) <doi:10.1186/s13059-022-02649-3>.

This package provides functions to design and apply tests that are anytime valid. The functions can be used to design hypothesis tests in the prospective/randomised control trial setting or in the observational/retrospective setting. The resulting tests remain valid under both optional stopping and optional continuation. The current version includes safe t-tests and safe tests of two proportions. For details on the theory of safe tests, see Ly, A, Boehm, Grunwald, Ramdas and van Ravenzwaaij (2024). "Safe Anytime-Valid Inference: Practical maximally flexible sampling designs for experiments based on e-values" (<doi:10.31234/osf.io/h5vae>) and Grunwald, de Heide and Koolen (2024) "Safe Testing" (<doi:10.1093/jrsssb/qkae011>), for details on safe logrank tests see ter Schure, Perez-Ortiz, Ly and Grunwald (2024) "The Anytime-Valid Logrank Test: Error Control under Continuous Monitoring with Unlimited Horizon" (<doi:10.51387/24-NEJSDS65>), and Turner, Ly and Grunwald (2024) "Generic E-variables for exact sequential k-sample tests that allow for optional stopping" (<doi:10.1016/j.jspi.2023.106116>) for details on safe contingency table tests.

Starting from a given object representing a fitted model (within a certain set of model classes) whose (non-)linear predictor includes some ordered factor(s) among the explanatory variables, a new model is constructed and fitted where each named factor is replaced by a single numeric score, suitably chosen so that the new variable produces a fit comparable with the standard methodology based on a set of polynomial contrasts. Two variants of the present approach have been developed, one in each of the next references: Azzalini (2023) <doi:10.1002/sta4.624>, (2024) <doi:10.48550/arXiv.2406.15933>.

Models with skewâ normally distributed and thus asymmetric error terms, implementing the methods developed in Badunenko and Henderson (2023) "Production analysis with asymmetric noise" <doi:10.1007/s11123-023-00680-5>. The package provides tools to estimate regression models with skewâ normal error terms, allowing both the variance and skewness parameters to be heteroskedastic. It also includes a stochastic frontier framework that accommodates both i.i.d. and heteroskedastic inefficiency terms.

This package provides GIS and map utilities, plus additional modeling tools for developing cellular automata, dynamic raster models, and agent based models in SpaDES'. Included are various methods for spatial spreading, spatial agents, GIS operations, random map generation, and others. See ?SpaDES.tools for a categorized overview of these additional tools.

Hail is an open-source, general-purpose, python based data analysis tool with additional data types and methods for working with genomic data, see <https://hail.is/>. Hail is built to scale and has first-class support for multi-dimensional structured data, like the genomic data in a genome-wide association study (GWAS). Hail is exposed as a python library, using primitives for distributed queries and linear algebra implemented in scala', spark', and increasingly C++'. The sparkhail is an R extension using sparklyr package. The idea is to help R users to use hail functionalities with the well-know tidyverse syntax, see <https://www.tidyverse.org/>.

To calculate the standard error of measurement (SEM) to assess the observer variability (inter- and intra-observer variation). The methods used in this package are referenced from Zoran B. PopoviÄ (2017) <doi:10.21037/cdt.2017.03.12>.