This package provides a Tcl/Tk Graphical User Interface (GUI) to display images than can be zoomed and panned using the mouse and keyboard shortcuts. tkImgR read and write different image formats (PPM/PGM, PNG and GIF) using the standard Tcl/Tk distribution (>=8.6), but other formats (JPEG, TIFF, CR2) can be handled using the tkImg package for Tcl/Tk'.

Fit a threshold regression model for Interval Censored Data based on the first-hitting-time of a boundary by the sample path of a Wiener diffusion process. The threshold regression methodology is well suited to applications involving survival and time-to-event data.

This package provides functions for point and interval estimation in error-in-variables models via total least squares or generalized total least squares method. See Golub and Van Loan (1980) <doi:10.1137/0717073>, Gleser (1981) <https://www.jstor.org/stable/2240867>, Ivan Markovsky and Huffel (2007) <doi:10.1016/j.sigpro.2007.04.004> for more information.

Infer constant and stochastic, time-dependent parameters to consider intrinsic stochasticity of a dynamic model and/or to analyze model structure modifications that could reduce model deficits. The concept is based on inferring time-dependent parameters as stochastic processes in the form of Ornstein-Uhlenbeck processes jointly with inferring constant model parameters and parameters of the Ornstein-Uhlenbeck processes. The package also contains functions to sample from and calculate densities of Ornstein-Uhlenbeck processes. References: Tomassini, L., Reichert, P., Kuensch, H.-R. Buser, C., Knutti, R. and Borsuk, M.E. (2009), A smoothing algorithm for estimating stochastic, continuous-time model parameters and its application to a simple climate model, Journal of the Royal Statistical Society: Series C (Applied Statistics) 58, 679-704, <doi:10.1111/j.1467-9876.2009.00678.x> Reichert, P., and Mieleitner, J. (2009), Analyzing input and structural uncertainty of nonlinear dynamic models with stochastic, time-dependent parameters. Water Resources Research, 45, W10402, <doi:10.1029/2009WR007814> Reichert, P., Ammann, L. and Fenicia, F. (2021), Potential and challenges of investigating intrinsic uncertainty of hydrological models with time-dependent, stochastic parameters. Water Resources Research 57(8), e2020WR028311, <doi:10.1029/2020WR028311> Reichert, P. (2022), timedeppar: An R package for inferring stochastic, time-dependent model parameters, in preparation.

Tsallis distribution also known as the q-exponential family distribution. Provide distribution d, p, q, r functions, fitting and testing functions. Project initiated by Paul Higbie and based on Cosma Shalizi's code.

Fits temperature response models to rate measurements taken at different temperatures. Etienne Low-Decarie,Tobias G. Boatman, Noah Bennett,Will Passfield,Antonio Gavalas-Olea,Philipp Siegel, Richard J. Geider (2017) <doi:10.1002/ece3.3576> .

Computes various entropies of given time series. This is the initial version that includes ApEn() and SampEn() functions for calculating approximate entropy and sample entropy. Approximate entropy was proposed by S.M. Pincus in "Approximate entropy as a measure of system complexity", Proceedings of the National Academy of Sciences of the United States of America, 88, 2297-2301 (March 1991). Sample entropy was proposed by J. S. Richman and J. R. Moorman in "Physiological time-series analysis using approximate entropy and sample entropy", American Journal of Physiology, Heart and Circulatory Physiology, 278, 2039-2049 (June 2000). This package also contains FastApEn() and FastSampEn() functions for calculating fast approximate entropy and fast sample entropy. These are newly designed very fast algorithms, resulting from the modification of the original algorithms. The calculated values of these entropies are not the same as the original ones, but the entropy trend of the analyzed time series determines equally reliably. Their main advantage is their speed, which is up to a thousand times higher. A scientific article describing their properties has been submitted to The Journal of Supercomputing and in present time it is waiting for the acceptance.

This package implements a method for identifying subgroups with superior response relative to the overall sample.

This package provides tools for constructing and analyzing two-phase experimental designs under correlated error structures. Version 1.1.1 includes improved efficiency factor classification with tolerance control, updated plot visualizations, and improved clarity of the results. The conceptual framework and the term two-phase were introduced by McIntyre (1955) <doi:10.2307/3001770>).

This package implements simulated tests for the hypothesis that terminal digits are uniformly distributed (chi-squared goodness-of-fit) and the hypothesis that terminal digits are independent from preceding digits (several tests of independence for r x c contingency tables). Also, for a number of distributions, implements Monte Carlo simulations for type I errors and power for the test of independence.

An integrated suite of tools for creating, maintaining, and reusing FAIR (Findable, Accessible, Interoperable, Reusable) theories. Designed to support transparent and collaborative theory development, the package enables users to formalize theories, track changes with version control, assess pre-empirical coherence, and derive testable hypotheses. Aligning with open science principles and workflows, theorytools facilitates the systematic improvement of theoretical frameworks and enhances their discoverability and usability.

Tidy tools for NetCDF data sources. Explore the contents of a NetCDF source (file or URL) presented as variables organized by grid with a database-like interface. The hyper_filter() interactive function translates the filter value or index expressions to array-slicing form. No data is read until explicitly requested, as a data frame or list of arrays via hyper_tibble() or hyper_array().

An opinionated, tidyverse-native toolkit for intensive longitudinal data (ILD). Encodes time structure, enforces within-between decomposition, provides spacing-aware lags, and integrates diagnostics and visualization. Use ild_prepare(), ild_center(), ild_lag(), and related functions for a unified pipeline from raw EMA/diary data to interpretable models.

Plant ecologists often need to collect "traits" data about plant species which are often scattered among various databases: TR8 contains a set of tools which take care of automatically retrieving some of those functional traits data for plant species from publicly available databases (The Ecological Flora of the British Isles, LEDA traitbase, Ellenberg values for Italian Flora, Mycorrhizal intensity databases, BROT, PLANTS, Jepson Flora Project). The TR8 name, inspired by "car plates" jokes, was chosen since it both reminds of the main object of the package and is extremely short to type.

Computation of t-year survival probabilities and t-year risks with right censored survival data. The Kaplan-Meier estimator is used to provide estimates for data without competing risks and the Aalen-Johansen estimator is used when there are competing risks. Confidence intervals and p-values are obtained using either usual Wald-type inference or empirical likelihood inference, as described in Thomas and Grunkemeier (1975) <doi:10.1080/01621459.1975.10480315> and Blanche (2020) <doi:10.1007/s10985-018-09458-6>. Functions for both one-sample and two-sample inference are provided. Unlike Wald-type inference, empirical likelihood inference always leads to consistent conclusions, in terms of statistical significance, when comparing two risks (or survival probabilities) via either a ratio or a difference.

This package provides functions for estimating times of common ancestry and molecular clock rates of evolution using a variety of evolutionary models, parametric and nonparametric bootstrap confidence intervals, methods for detecting outlier lineages, root-to-tip regression, and a statistical test for selecting molecular clock models. For more details see Volz and Frost (2017) <doi:10.1093/ve/vex025>.

General framework to organize data, methods, and results used in reproducible scientific analyses. A TAF analysis consists of four scripts (data.R, model.R, output.R, report.R) that are run sequentially. Each script starts by reading files from a previous step and ends with writing out files for the next step. Convenience functions are provided to version control the required data and software, run analyses, clean residues from previous runs, manage files, manipulate tables, and produce figures. With a focus on stability and reproducible analyses, the TAF package comes with no dependencies. TAF forms a base layer for the icesTAF package and other scientific applications.

This package provides a toolkit of tidy data manipulation verbs with data.table as the backend. Combining the merits of syntax elegance from dplyr and computing performance from data.table', tidyfst intends to provide users with state-of-the-art data manipulation tools with least pain. This package is an extension of data.table'. While enjoying a tidy syntax, it also wraps combinations of efficient functions to facilitate frequently-used data operations.

Tri-hierarchical incomplete block design is defined as an arrangement of v treatments each replicated r times in a three system of blocks if, each block of the first system contains m_1 blocks of second system and each block of the second system contains m_2 blocks of the third system. Ignoring the first and second system of blocks, it leaves an incomplete block design with b_3 blocks of size k_3i units; ignoring first and third system of blocks, it leaves an incomplete block design with b_2 blocks each of size k_2i units and ignoring the second and third system of blocks, it leaves an incomplete block design with b_1 blocks each of size k_1 units. For dealing with experimental circumstances where there are three nested sources of variation, a tri-hierarchical incomplete block design can be adopted. Tri - hierarchical incomplete block designs can find application potential in obtaining mating-environmental designs for breeding trials. To know more about nested block designs one can refer Preece (1967) <doi:10.1093/biomet/54.3-4.479>. This package includes series1(), series2(), series3() and series4() functions. This package generates tri-hierarchical designs with six component designs under certain parameter restrictions.

This package provides functions to combine data.frames in ways that require additional effort in base R, and to add metadata (id, title, ...) that can be used for printing and xlsx export. The Tatoo_report class is provided as a convenient helper to write several such tables to a workbook, one table per worksheet. Tatoo is built on top of openxlsx', but intimate knowledge of that package is not required to use tatoo.

Likelihood-based estimation of mixed-effects transformation models using the Template Model Builder ('TMB', Kristensen et al., 2016) <doi:10.18637/jss.v070.i05>. The technical details of transformation models are given in Hothorn et al. (2018) <doi:10.1111/sjos.12291>. Likelihood contributions of exact, randomly censored (left, right, interval) and truncated observations are supported. The random effects are assumed to be normally distributed on the scale of the transformation function, the marginal likelihood is evaluated using the Laplace approximation, and the gradients are calculated with automatic differentiation (Tamasi & Hothorn, 2021) <doi:10.32614/RJ-2021-075>. Penalized smooth shift terms can be defined using the mgcv notation. Additive mixed-effects transformation models are described in Tamasi (2025) <doi:10.18637/jss.v114.i11>.

This package provides a tool for comprehensive transcriptomic data analysis, with a focus on transcript-level data preprocessing, expression profiling, differential expression analysis, and functional enrichment. It enables researchers to identify key biological processes, disease biomarkers, and gene regulatory mechanisms. TransProR is aimed at researchers and bioinformaticians working with RNA-Seq data, providing an intuitive framework for in-depth analysis and visualization of transcriptomic datasets. The package includes comprehensive documentation and usage examples to guide users through the entire analysis pipeline. The differential expression analysis methods incorporated in the package include limma (Ritchie et al., 2015, <doi:10.1093/nar/gkv007>; Smyth, 2005, <doi:10.1007/0-387-29362-0_23>), edgeR (Robinson et al., 2010, <doi:10.1093/bioinformatics/btp616>), DESeq2 (Love et al., 2014, <doi:10.1186/s13059-014-0550-8>), and Wilcoxon tests (Li et al., 2022, <doi:10.1186/s13059-022-02648-4>), providing flexible and robust approaches to RNA-Seq data analysis. For more information, refer to the package vignettes and related publications.

There are some experimental scenarios where each experimental unit receives a sequence of treatments across multiple periods, and treatment effects persist beyond the period of application. It focuses on the construction and calculation of the parametric value of the residual effect designs balanced for carryover effects, also referred to as crossover designs, change-over designs, or repeated measurements designs (Aggarwal and Jha, 2010<doi:10.1080/15598608.2010.10412013>). The primary objective of the package is to generate a new class of Balanced Ternary Residual Effect Designs (BTREDs), balanced for carryover effects tailored explicitly for situations where the number of periods is less than or equal to the number of treatments. In addition, the package provides four new classes of Partially Balanced Ternary Residual Effect Designs (PBTREDs), constructed using incomplete block designs, initial sequences, and rectangular association scheme. In addition, one extra function is included to help study the parametric properties of a given residual effect design.

This package creates some tables of clinical study. Table 1 is created by table1() to describe baseline characteristics, which is essential in every clinical study. Created by table2(), the function of Table 2 is to explore influence factors. And Table 3 created by table3() is able to make stratified analysis.