This package provides a system that provides a streamlined way of generating publication ready plots for known Single-Cell transcriptomics data in a â publication readyâ format. This is, the goal is to automatically generate plots with the highest quality possible, that can be used right away or with minimal modifications for a research article.

This package provides several Bayesian survival models for spatial/non-spatial survival data: proportional hazards (PH), accelerated failure time (AFT), proportional odds (PO), and accelerated hazards (AH), a super model that includes PH, AFT, PO and AH as special cases, Bayesian nonparametric nonproportional hazards (LDDPM), generalized accelerated failure time (GAFT), and spatially smoothed Polya tree density estimation. The spatial dependence is modeled via frailties under PH, AFT, PO, AH and GAFT, and via copulas under LDDPM and PH. Model choice is carried out via the logarithm of the pseudo marginal likelihood (LPML), the deviance information criterion (DIC), and the Watanabe-Akaike information criterion (WAIC). See Zhou, Hanson and Zhang (2020) <doi:10.18637/jss.v092.i09>.

This package implements different kinds of bootstraps to estimate sampling variation from survey data with complex designs. Includes the rescaled bootstrap described in Rust and Rao (1996) <doi:10.1177/096228029600500305> and Rao and Wu (1988) <doi:10.1080/01621459.1988.10478591>.

Fits singular linear models to longitudinal data. Singular linear models are useful when the number, or timing, of longitudinal observations may be informative about the observations themselves. They are described in Farewell (2010) <doi:10.1093/biomet/asp068>, and are extensions of the linear increments model <doi:10.1111/j.1467-9876.2007.00590.x> to general longitudinal data.

This package provides functionality to fit and simulate from stationary vine copula models for time series, see Nagler et al. (2022) <doi:10.1016/j.jeconom.2021.11.015>.

This package provides a pipeline for estimating the average treatment effect via semi-supervised learning. Outcome regression is fit with cross-fitting using various machine learning method or user customized function. Doubly robust ATE estimation leverages both labeled and unlabeled data under a semi-supervised missing-data framework. For more details see Hou et al. (2021) <doi:10.48550/arxiv.2110.12336>. A detailed vignette is included.

Fits, spatially predicts and temporally forecasts large amounts of space-time data using [1] Bayesian Gaussian Process (GP) Models, [2] Bayesian Auto-Regressive (AR) Models, and [3] Bayesian Gaussian Predictive Processes (GPP) based AR Models for spatio-temporal big-n problems. Bakar and Sahu (2015) <doi:10.18637/jss.v063.i15>.

Imbalanced training datasets impede many popular classifiers. To balance training data, a combination of oversampling minority classes and undersampling majority classes is useful. This package implements the SCUT (SMOTE and Cluster-based Undersampling Technique) algorithm as described in Agrawal et. al. (2015) <doi:10.5220/0005595502260234>. Their paper uses model-based clustering and synthetic oversampling to balance multiclass training datasets, although other resampling methods are provided in this package.

Generates a random quotation from a database of quotes on topics in statistics, data visualization and science. Other functions allow searching the quotes database by key term tags, or authors or creating a word cloud. The output is designed to be suitable for use at the console, in Rmarkdown and LaTeX.

This package implements a set of distribution modeling methods that are suited to species with small sample sizes (e.g., poorly sampled species or rare species). While these methods can also be used on well-sampled taxa, they are united by the fact that they can be utilized with relatively few data points. More details on the currently implemented methodologies can be found in Maitner et al. (2026) <doi:10.1002/ecog.08112>, Drake and Richards (2018) <doi:10.1002/ecs2.2373>, Drake (2015) <doi:10.1098/rsif.2015.0086>, and Drake (2014) <doi:10.1890/ES13-00202.1>.

Takes as input a stable oxygen isotope (d18O) profile measured in growth direction (D) through a shell + uncertainties in both variables (d18O_err & D_err). It then models the seasonality in the d18O record by fitting a combination of a growth and temperature sine wave to year-length chunks of the data (see Judd et al., (2018) <doi:10.1016/j.palaeo.2017.09.034>). This modeling is carried out along a sliding window through the data and yields estimates of the day of the year (Julian Day) and local growth rate for each data point. Uncertainties in both modeling routine and the data itself are propagated and pooled to obtain a confidence envelope around the age of each data point in the shell. The end result is a shell chronology consisting of estimated ages of shell formation relative to the annual cycle with their uncertainties. All formulae in the package serve this purpose, but the user can customize the model (e.g. number of days in a year and the mineralogy of the shell carbonate) through input parameters.

Enforcement of field types in lists. A drop-in tool to allow for dynamic input data that might be questionably parsed or cast to be coerced into the specific desired format in a reasonably performant manner.

This package provides developer-focused helper functions and S3 classes to ease the creation of structured subtypes of data frames. Developers can require certain columns and types to be present, and can enforce crossing and nesting relationships between values in different columns. Type-specific metadata and attributes are preserved through common data frame manipulations.

Create a skeleton shiny application with create_template() that is reproducible, can be saved and meets academic standards for attribution. Forked from wallace'. Code is split into modules that are loaded and linked together automatically and each call one function. Guidance pages explain modules to users and flexible logging informs them of any errors. Options enable asynchronous operations, viewing of source code, interactive maps and data tables. Use to create complex analytical applications, following best practices in open science and software development. Includes functions for automating repetitive development tasks and an example application at run_shinyscholar() that requires install.packages("shinyscholar", dependencies = TRUE). A guide to developing applications can be found on the package website.

There are several functions to implement the method for analysis in a randomized clinical trial with strata with following key features. A stratified Mann-Whitney estimator addresses the comparison between two randomized groups for a strictly ordinal response variable. The multivariate vector of such stratified Mann-Whitney estimators for multivariate response variables can be considered for one or more response variables such as in repeated measurements and these can have missing completely at random (MCAR) data. Non-parametric covariance adjustment is also considered with the minimal assumption of randomization. The p-value for hypothesis test and confidence interval are provided.

This package provides functions to take samples of data, sample size estimation and getting useful estimators such as total, mean, proportion about its population using simple random, stratified, systematic and cluster sampling.

This package implements the Savvy Parity Regression savvyPR methodology for multivariate linear regression analysis. The package solves an optimization problem that balances the contribution of each predictor variable to ensure estimation stability in the presence of multicollinearity. It supports two distinct parameterization methods, a Budget-based approach that allocates a fixed loss contribution to each predictor, and a Target-based approach (t-tuning) that utilizes a relative elasticity weight for the response variable. The package provides comprehensive tools for model estimation, risk distribution analysis, and parameter tuning via cross-validation (PR1, PR2, and PR3 model types) to optimize predictive accuracy. Methods are based on Asimit, Chen, Ichim and Millossovich (2026) <https://openaccess.city.ac.uk/id/eprint/37017/>.

Find non-linear formulas that fits your input data. You can systematically explore and memorize the possible formulas and it's cross-validation performance, in an incremental fashion. Three main interoperable search functions are available: 1) random.search() performs a random exploration, 2) genetic.search() employs a genetic optimization algorithm, 3) comb.search() combines best results of the first two. For more details see Tomasoni et al. (2026) <doi:10.1208/s12248-026-01232-z>.

This package provides a classification framework to use expression patterns of pathways as features to identify similarity between biological samples. It provides a new measure for quantifying similarity between expression patterns of pathways.

We develop a new class of distribution free multiple testing rules for false discovery rate (FDR) control under general dependence. A key element in our proposal is a symmetrized data aggregation (SDA) approach to incorporating the dependence structure via sample splitting, data screening and information pooling. The proposed SDA filter first constructs a sequence of ranking statistics that fulfill global symmetry properties, and then chooses a data driven threshold along the ranking to control the FDR. For more information, see the website below and the accompanying paper: Du et al. (2023), "False Discovery Rate Control Under General Dependence By Symmetrized Data Aggregation", <doi:10.1080/01621459.2021.1945459>. Some optional functionality uses the archived R packages â hugeâ and â pfaâ , which are not available from CRANâ s main repositories. Users who need this optional functionality can obtain them from the CRAN Archive as follows: â hugeâ at <https://cran.r-project.org/src/contrib/Archive/huge/>; â pfaâ at <https://cran.r-project.org/src/contrib/Archive/pfa/>.

Analyze public-use micro data from the Survey of Consumer Finances. Provides tools to download prepared data files, construct replicate-weighted multiply imputed survey designs, compute descriptive statistics and model estimates, and produce plots and tables. Methods follow design-based inference for complex surveys and pooling across multiple imputations. See the package website and the code book for background.

Taxonomic dictionaries, formative element lists, and functions related to the maintenance, development and application of U.S. Soil Taxonomy. Data and functionality are based on official U.S. Department of Agriculture sources including the latest edition of the Keys to Soil Taxonomy. Descriptions and metadata are obtained from the National Soil Information System or Soil Survey Geographic databases. Other sources are referenced in the data documentation. Provides tools for understanding and interacting with concepts in the U.S. Soil Taxonomic System. Most of the current utilities are for working with taxonomic concepts at the "higher" taxonomic levels: Order, Suborder, Great Group, and Subgroup.

Maximum-likelihood estimation of the spatial autoregressive stochastic frontier model with individual fixed effects (removed by first differencing) and endogenous regressors handled through a Gaussian control function, as in Giannini (2025) <doi:10.1080/17421772.2024.2414962>. Returns coefficient estimates and standard errors, spatially-corrected technical (in)efficiency scores, and direct, indirect and total marginal impacts. Depends only on base R.

This package implements the SelectSim methodology for identifying patterns of co-occurrence and mutual exclusivity between functional genomic alterations in cancer cohorts. The package processes mutation annotation data, constructs alteration matrices, estimates expected alteration-pair frequencies, and quantifies deviations associated with selective interactions. The methodology is described in Iyer et al. (2026) <doi:10.1038/s41588-026-02661-4>.