The Time-Delay Correlation algorithm (TDCor) reconstructs the topology of a gene regulatory network (GRN) from time-series transcriptomic data. The algorithm is described in details in Lavenus et al., Plant Cell, 2015. It was initially developed to infer the topology of the GRN controlling lateral root formation in Arabidopsis thaliana. The time-series transcriptomic dataset which was used in this study is included in the package to illustrate how to use it.

This package provides a diverse collection of time series datasets spanning various fields such as economics, finance, energy, healthcare, and more. Designed to support time series analysis in R by offering datasets from multiple disciplines, making it a valuable resource for researchers and analysts.

This package performs model-based tensor clustering methods including Tensor Gaussian Mixture Model (TGMM), Tensor Envelope Mixture Model (TEMM) by Deng and Zhang (2021) <DOI: 10.1111/biom.13486>, Doubly-Enhanced EM (DEEM) algorithm by Mai, Zhang, Pan and Deng (2021) <DOI: 10.1080/01621459.2021.1904959>.

Fits Bayesian finite mixtures with an unknown number of components using the telescoping sampler and different component distributions. For more details see Frühwirth-Schnatter et al. (2021) <doi:10.1214/21-BA1294>, Malsiner-Walli et al. (in press) <doi:10.1007/s11634-025-00640-x> and Malsiner-Walli et al. (2026) <doi:10.48550/arXiv.2603.00277>.

This package implements an algorithm for generating maps, known as tile maps, in which each region is represented by a single tile of the same shape and size. The algorithm was first proposed in "Generating Tile Maps" by Graham McNeill and Scott Hale (2017) <doi:10.1111/cgf.13200>. Functions allow users to generate, plot, and compare square or hexagon tile maps.

Download TIGER/Line shapefiles from the United States Census Bureau (<https://www.census.gov/geographies/mapping-files/time-series/geo/tiger-line-file.html>) and load into R as sf objects.

This package provides tools for simulating and modeling traffic flow on road networks using spatial conditional autoregressive (CAR) models. The package represents road systems as graphs derived from OpenStreetMap data <https://www.openstreetmap.org/> and supports network-based spatial dependence, basic preprocessing, and visualization for spatial traffic analysis.

The TEQR package contains software to calculate the operating characteristics for the TEQR and the ACT designs.The TEQR (toxicity equivalence range) design is a toxicity based cumulative cohort design with added safety rules. The ACT (Activity constrained for toxicity) design is also a cumulative cohort design with additional safety rules. The unique feature of this design is that dose is escalated based on lack of activity rather than on lack of toxicity and is de-escalated only if an unacceptable level of toxicity is experienced.

The classical two-sample t-test works well for the normally distributed data or data with large sample size. The tcfu() and tt() tests implemented in this package provide better type-I-error control with more accurate power when testing the equality of two-sample means for skewed populations having unequal variances. These tests are especially useful when the sample sizes are moderate. The tcfu() uses the Cornish-Fisher expansion to achieve a better approximation to the true percentiles. The tt() provides transformations of the Welch's t-statistic so that the sampling distribution become more symmetric. For more technical details, please refer to Zhang (2019) <http://hdl.handle.net/2097/40235>.

Simple definition of time intervals for the current, previous, and next week, month, quarter and year.

When plotting treated-minus-control differences, after-minus-before changes, or difference-in-differences, the ttrans() function symmetrically transforms the positive and negative tails to aid plotting. The package includes an observational study with three control groups and an unaffected outcome; see Rosenbaum (2022) <doi:10.1080/00031305.2022.2063944>.

An R wrapper for the Spotify Web API <https://developer.spotify.com/web-api/>.

Estimation of transition probabilities for the illness-death model and or the three-state progressive model.

Tensor-train is a compact representation for higher-order tensors. Some algorithms for performing tensor-train decomposition are available such as TT-SVD, TT-WOPT, and TT-Cross. For the details of the algorithms, see I. V. Oseledets (2011) <doi:10.1137/090752286>, Yuan Longao, et al (2017) <doi:10.48550/arXiv.1709.02641>, I. V. Oseledets (2010) <doi:10.1016/j.laa.2009.07.024>.

User-friendly analysis of hierarchical multinomial processing tree (MPT) models that are often used in cognitive psychology. Implements the latent-trait MPT approach (Klauer, 2010) <DOI:10.1007/s11336-009-9141-0> and the beta-MPT approach (Smith & Batchelder, 2010) <DOI:10.1016/j.jmp.2009.06.007> to model heterogeneity of participants. MPT models are conveniently specified by an .eqn-file as used by other MPT software and data are provided by a .csv-file or directly in R. Models are either fitted by calling JAGS or by an MPT-tailored Gibbs sampler in C++ (only for nonhierarchical and beta MPT models). Provides tests of heterogeneity and MPT-tailored summaries and plotting functions. A detailed documentation is available in Heck, Arnold, & Arnold (2018) <DOI:10.3758/s13428-017-0869-7> and a tutorial on MPT modeling can be found in Schmidt, Erdfelder, & Heck (2023) <DOI:10.1037/met0000561>.

Manage time-series data frames across time zones, resolutions, and date ranges, while filling gaps using weekday/hour patterns or simple fill helpers or plotting them interactively. It is designed to work seamlessly with the tidyverse and dygraphs environments.

This package provides a hypothesis test and variable selection algorithm for use in time-varying, concurrent regression models. The hypothesis test function is also accompanied by a plotting function which will show the estimated beta(s) and confidence band(s) from the hypothesis test. The hypothesis test function helps the user identify significant covariates within the scope of a time-varying concurrent model. The plots will show the amount of area that falls outside the confidence band(s) which is used for the test statistic within the hypothesis test.

Perform two types of analysis: 1) checking the goodness-of-fit of tree models to your single-cell gene expression data; and 2) deciding which tree best fits your data.

Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques). The package is based on the method described in Massa M.S., Chiogna M., Romualdi C. (2010) <doi:10.1186/1752-0509-4-121>.

Pre-process for discrete time series data set which is not continuous at the column of date'. Refilling records of missing date and other columns to the hollow data set so that final data set is able to be dealt with time series analysis.

Package designed for working with vectors and lists of vectors, mainly for turning them into other indexed data structures.

Different multiple testing procedures for correlation tests are implemented. These procedures were shown to theoretically control asymptotically the Family Wise Error Rate (Roux (2018) <https://tel.archives-ouvertes.fr/tel-01971574v1>) or the False Discovery Rate (Cai & Liu (2016) <doi:10.1080/01621459.2014.999157>). The package gather four test statistics used in correlation testing, four FWER procedures with either single step or stepdown versions, and four FDR procedures.

Calculates the number of true positives and false positives from a dataset formatted for Jackknife alternative free-response receiver operating characteristic which is used for statistical analysis which is explained in the book Chakraborty DP (2017), "Observer Performance Methods for Diagnostic Imaging - Foundations, Modeling, and Applications with R-Based Examples", Taylor-Francis <https://www.crcpress.com/9781482214840>.

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.