Estimate vaccine efficacy (VE) using immunogenicity data. The inclusion of immunogenicity data in regression models can increase precision in VE. The methods are described in the publications "Elucidating vaccine efficacy using a correlate of protection, demographics, and logistic regression" and "Improving precision of vaccine efficacy evaluation using immune correlate data in time-to-event models" by Julie Dudasova, Zdenek Valenta, and Jeffrey R. Sachs (2024).

Visual contour and 2D point and contour plots for binary classification modeling under algorithms such as glm', rf', gbm', nnet and svm', presented over two dimensions generated by famd and mca methods. Package FactoMineR for multivariate reduction functions and package MBA for interpolation functions are used. The package can be used to visualize the discriminant power of input variables and algorithmic modeling, explore outliers, compare algorithm behaviour, etc. It has been created initially for teaching purposes, but it has also many practical uses under the XAI paradigm.

Utilizes multiple variable selection methods to estimate Average Treatment Effect.

Using frequency matrices, very low frequency variants (VLFs) are assessed for amino acid and nucleotide sequences. The VLFs are then compared to see if they occur in only one member of a species, singleton VLFs, or if they occur in multiple members of a species, shared VLFs. The amino acid and nucleotide VLFs are then compared to see if they are concordant with one another. Amino acid VLFs are also assessed to determine if they lead to a change in amino acid residue type, and potential changes to protein structures. Based on Stoeckle and Kerr (2012) <doi:10.1371/journal.pone.0043992> and Phillips et al. (2023) <doi:10.3897/BDJ.11.e96480>.

This package creates Vertex Similarity matrix of an undirected graph based on the method stated by E. A. Leicht, Petter Holme, AND M. E. J. Newman in their paper <DOI:10.1103/PhysRevE.73.026120>.

This package provides tools to generate virtual environmental drivers with a given temporal autocorrelation, and to simulate pollen curves at annual resolution over millennial time-scales based on these drivers and virtual taxa with different life traits and niche features. It also provides the means to simulate quasi-realistic pollen-data conditions by applying simulated accumulation rates and given depth intervals between consecutive samples.

This package provides methods for calculating the variance scale exponent to identify memory patterns in time series data. Includes tests for white noise, short memory, and long memory. See Fu, H. et al. (2018) <doi:10.1016/j.physa.2018.06.092>.

Data version management on the file system for smaller projects. Manage data pipeline outputs with symbolic folder links, structured logging and reports, using R6 classes for encapsulation and data.table for speed. Directory-specific logs used as source of truth to allow portability of versioned data folders.

This package contains logic for cell-specific gene set scoring of single cell RNA sequencing data.

Uses large language models to create poems about R packages. Currently contains the roses() function to make "roses are red, ..." style poems and the prompt() function to only assemble the prompt without submitting it to the model.

Fits generalized additive models (GAMs) using a variational approximations (VA) framework. In brief, the VA framework provides a fully or at least closed to fully tractable lower bound approximation to the marginal likelihood of a GAM when it is parameterized as a mixed model (using penalized splines, say). In doing so, the VA framework aims offers both the stability and natural inference tools available in the mixed model approach to GAMs, while achieving computation times comparable to that of using the penalized likelihood approach to GAMs. See Hui et al. (2018) <doi:10.1080/01621459.2018.1518235>.

Predicate helper functions for testing atomic vectors in R. All functions take a single argument x and check whether it's of the target type of base-R atomic vector (i.e. no class extensions nor attributes other than names'), returning TRUE or FALSE. Some additionally check for value (e.g. absence of missing values, infinities, blank characters, or names attribute; or having length 1).

This package provides tools for visibility analysis in geospatial data. It offers functionality to perform isovist calculations, using arbitrary geometries as both viewpoints and occluders.

Models categorical time series through a Markov Chain when a) covariates are predictors for transitioning into the next state/symbol and b) when the dependence in the past states has variable length. The probability of transitioning to the next state in the Markov Chain is defined by a multinomial regression whose parameters depend on the past states of the chain and, moreover, the number of states in the past needed to predict the next state also depends on the observed states themselves. See Zambom, Kim, and Garcia (2022) <doi:10.1111/jtsa.12615>.

Simulates and evaluates stochastic scenarios of death and lapse events in life reinsurance contracts with profit commissions. The methodology builds on materials published by the Institute of Actuaries of Japan <https://www.actuaries.jp/examin/textbook/pdf/modeling.pdf>. A paper describing the detailed algorithms will be published by the author within a few months after the initial release of this package.

Offers a wide range of functions for reading and writing data in various file formats, including CSV, RDS, Excel and ZIP files. Additionally, it provides functions for retrieving metadata associated with files, such as file size and creation date, making it easy to manage and organize large data sets. This package is designed to simplify data import and export tasks, and provide users with a comprehensive set of tools to work with different types of data files.

This package implements a maximum likelihood estimation (MLE) method for estimation and prediction of Gaussian process-based spatially varying coefficient (SVC) models (Dambon et al. (2021a) <doi:10.1016/j.spasta.2020.100470>). Covariance tapering (Furrer et al. (2006) <doi:10.1198/106186006X132178>) can be applied such that the method scales to large data. Further, it implements a joint variable selection of the fixed and random effects (Dambon et al. (2021b) <doi:10.1080/13658816.2022.2097684>). The package and its capabilities are described in (Dambon et al. (2021c) <doi:10.48550/arXiv.2106.02364>).

Variational Autoencoded Multivariate Spatial Fay-Herriot models are designed to efficiently estimate population parameters in small area estimation. This package implements the variational generalized multivariate spatial Fay-Herriot model (VGMSFH) using NumPyro and PyTorch backends, as demonstrated by Wang, Parker, and Holan (2025) <doi:10.48550/arXiv.2503.14710>. The vmsae package provides utility functions to load weights of the pretrained variational autoencoders (VAEs) as well as tools to train custom VAEs tailored to users specific applications.

Extendable R6 file comparison classes, including a shiny app for combining the comparison functionality into a file comparison application. The package idea originates from pharma companies drug development processes, where statisticians and statistical programmers need to review and compare different versions of the same outputs and datasets. The package implementation itself is not tied to any specific industry and can be used in any context for easy file comparisons between different file version sets.

Debugging pipe chains often consists of viewing the output after each step. This package adds RStudio addins and two functions that allow outputing each or select steps in a convenient way.

Elaboration of vehicular emissions inventories, consisting in four stages, pre-processing activity data, preparing emissions factors, estimating the emissions and post-processing of emissions in maps and databases. More details in Ibarra-Espinosa et al (2018) <doi:10.5194/gmd-11-2209-2018>. Before using VEIN you need to know the vehicular composition of your study area, in other words, the combination of of type of vehicles, size and fuel of the fleet. Then, it is recommended to start with the project to download a template to create a structure of directories and scripts.

Simplifies and largely automates practical voice analytics for social science research. This package offers an accessible and easy-to-use interface, including an interactive Shiny app, that simplifies the processing, extraction, analysis, and reporting of voice recording data in the behavioral and social sciences. The package includes batch processing capabilities to read and analyze multiple voice files in parallel, automates the extraction of key vocal features for further analysis, and automatically generates APA formatted reports for typical between-group comparisons in experimental social science research. A more extensive methodological introduction that inspired the development of the voiceR package is provided in Hildebrand et al. 2020 <doi:10.1016/j.jbusres.2020.09.020>.

The biomarker data set by Vermeulen et al. (2009) <doi:10.1016/S1470-2045(09)70154-8> is provided. The data source, however, is by Ruijter et al. (2013) <doi:10.1016/j.ymeth.2012.08.011>. The original data set may be downloaded from <https://medischebiologie.nl/wp-content/uploads/2019/02/qpcrdatamethods.zip>. This data set is for a real-time quantitative polymerase chain reaction (PCR) experiment that comprises the raw fluorescence data of 24,576 amplification curves. This data set comprises 59 genes of interest and 5 reference genes. Each gene was assessed on 366 neuroblastoma complementary DNA (cDNA) samples and on 18 standard dilution series samples (10-fold 5-point dilution series x 3 replicates + no template controls (NTC) x 3 replicates).

This package provides a collection of functions to make R a more effective viewscape analysis tool for calculating viewscape metrics based on computing the viewable area for given a point/multiple viewpoints and a digital elevation model.The method of calculating viewscape metrics implemented in this package are based on the work of Tabrizian et al. (2020) <doi:10.1016/j.landurbplan.2019.103704>. The algorithm of computing viewshed is based on the work of Franklin & Ray. (1994) <https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=555780f6f5d7e537eb1edb28862c86d1519af2be>.