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An educational toolkit for learning statistical concepts through interactive exploration. Provides functions for basic statistics (mean, variance, etc.) and probability distributions with step-by-step explanations and interactive learning modes. Each function can be used for simple calculations, detailed learning with explanations, or interactive practice with feedback.
This package implements empirical Bayes approaches to genotype polyploids from next generation sequencing data while accounting for allele bias, overdispersion, and sequencing error. The main functions are flexdog() and multidog(), which allow the specification of many different genotype distributions. Also provided are functions to simulate genotypes, rgeno(), and read-counts, rflexdog(), as well as functions to calculate oracle genotyping error rates, oracle_mis(), and correlation with the true genotypes, oracle_cor(). These latter two functions are useful for read depth calculations. Run browseVignettes(package = "updog") in R for example usage. See Gerard et al. (2018) <doi:10.1534/genetics.118.301468> and Gerard and Ferrao (2020) <doi:10.1093/bioinformatics/btz852> for details on the implemented methods.
Density, distribution function, quantile function, and random generating function of the Unit-Garima distribution based on Ayuyuen, S., & Bodhisuwan, W. (2024)<doi:10.18187/pjsor.v20i1.4307>.
Supervised classification methods, which (if asked) can provide step-by-step explanations of the algorithms used, as described in PK Josephine et. al., (2021) <doi:10.59176/kjcs.v1i1.1259>; and datasets to test them on, which highlight the strengths and weaknesses of each technique.
The udder quarter infection data set contains infection times of individual cow udder quarters with Corynebacterium bovis (Laevens et al. 1997 <DOI:10.3168/jds.S0022-0302(97)76295-7>). Obviously, the four udder quarters are clustered within a cow, and udder quarters are sampled only approximately monthly, generating interval-censored data. The data set contains both covariates that change within a cow (e.g., front and rear udder quarters) and covariates that change between cows (e.g., parity [the number of previous calvings]). The correlation between udder infection times within a cow also is of interest, because this is a measure of the infectivity of the agent causing the disease. Various models have been applied to address the problem of interdependence for right-censored event times. These models, as applied to this data set, can be found back in the publications found in the reference list.
This package provides functions to query the UniTCM API (<https://unitcm.qfxulab.com>), covering herb exploration, compound/ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) data, disease-formula associations, Traditional Chinese Medicine (TCM) ontology, transcriptomics, and gene-disease analysis (MIDAS, Mining Integrated Disease Association Sources).
Detects values imported from spreadsheets that were auto-converted to Excel date serials and reconstructs the originally intended day.month decimals (for example, 30.3 that Excel displayed as 30/03/2025'). The functions work in a vectorized manner, preserve non-serial values, and support both the 1900 and 1904 date systems.
This is a framework that aims to provide methods and tools for assessing the impact of different sources of uncertainties (e.g.positional uncertainty) on performance of species distribution models (SDMs).).
This program realizes a universal estimation approach that accommodates multi-category variables and effect scales, making up for the deficiencies of the existing approaches when dealing with non-binary exposures and complex models. The estimation via bootstrapping can simultaneously provide results of causal mediation on risk difference (RD), odds ratio (OR) and risk ratio (RR) scales with tests of the effects difference. The estimation is also applicable to many other settings, e.g., moderated mediation, inconsistent covariates, panel data, etc. The high flexibility and compatibility make it possible to apply for any type of model, greatly meeting the needs of current empirical researches.
Implementation of the unity forest (UFO) framework (Hornung & Hapfelmeier, 2026, <doi:10.48550/arXiv.2601.07003>). UFOs are a random forest variant designed to better take covariates with purely interaction-based effects into account, including interactions for which none of the involved covariates exhibits a marginal effect. While this framework tends to improve discrimination and predictive accuracy compared to standard random forests, it also facilitates the identification and interpretation of (marginal or interactive) effects: In addition to the UFO algorithm for tree construction, the package includes the unity variable importance measure (unity VIM), which quantifies covariate effects under the conditions in which they are strongest - either marginally or within subgroups defined by interactions - as well as covariate-representative tree roots (CRTRs) that provide interpretable visualizations of these conditions. Categorical and continuous outcomes are supported. This package is a fork of the R package ranger (main author: Marvin N. Wright), which implements random forests using an efficient C++ backend.
Pseudo-random number generation of 17 univariate distributions proposed by Demirtas. (2005) <DOI:10.22237/jmasm/1114907220>.
In many phase I trials, the design goal is to find the dose associated with a certain target toxicity rate. In some trials, the goal can be to find the dose with a certain weighted sum of rates of various toxicity grades. For others, the goal is to find the dose with a certain mean value of a continuous response. This package provides the setup and calculations needed to run a dose-finding trial with non-binary endpoints and performs simulations to assess designâ s operating characteristics under various scenarios. Three dose finding designs are included in this package: unified phase I design (Ivanova et al. (2009) <doi:10.1111/j.1541-0420.2008.01045.x>), Quasi-CRM/Robust-Quasi-CRM (Yuan et al. (2007) <doi:10.1111/j.1541-0420.2006.00666.x>, Pan et al. (2014) <doi:10.1371/journal.pone.0098147>) and generalized BOIN design (Mu et al. (2018) <doi:10.1111/rssc.12263>). The toxicity endpoints can be handled with these functions including equivalent toxicity score (ETS), total toxicity burden (TTB), general continuous toxicity endpoints, with incorporating ordinal grade toxicity information into dose-finding procedure. These functions allow customization of design characteristics to vary sample size, cohort sizes, target dose-limiting toxicity (DLT) rates, discrete or continuous toxicity score, and incorporate safety and/or stopping rules.
This package provides a generic reference Bayesian analysis of unidimensional mixture distributions obtained by a location-scale parameterisation of the model is implemented. The including functions simulate and summarize posterior samples for location-scale mixture models using a weakly informative prior. There is no need to define priors for scale-location parameters except two hyperparameters in which are associated with a Dirichlet prior for weights and a simplex.
This package provides a variational mapping approach that reveals and expands future temporal dynamics from folded high-dimensional geometric distance spaces, unfold turns a set of time series into a 4D block of pairwise distances between reframed windows, learns a variational mapper that maps those distances to the next reframed window, and produces horizon-wise predictive functions for each input series. In short: it unfolds the future path of each series from a folded geometric distance representation.
Retrieve data from the UNESCO Institute for Statistics (UIS) API <https://api.uis.unesco.org/api/public/documentation/>. UIS provides public access to more than 4,000 indicators focusing on education, science and technology, culture, and communication.
This package provides a classification (decision) tree is constructed from survival data with high-dimensional covariates. The method is a robust version of the logrank tree, where the variance is stabilized. The main function "uni.tree" returns a classification tree for a given survival dataset. The inner nodes (splitting criterion) are selected by minimizing the P-value of the two-sample the score tests. The decision of declaring terminal nodes (stopping criterion) is the P-value threshold given by an argument (specified by user). This tree construction algorithm is proposed by Emura et al. (2021, in review).
The Unmanned Aerial Vehicle Mission Planner provides an easy to use work flow for planning autonomous obstacle avoiding surveys of ready to fly unmanned aerial vehicles to retrieve aerial or spot related data. It creates either intermediate flight control files for the DJI-Litchi supported series or ready to upload control files for the pixhawk-based flight controller. Additionally it contains some useful tools for digitizing and data manipulation.
UNIfied Cross-Omics deconvolution (Unico) deconvolves standard 2-dimensional bulk matrices of samples by features into a 3-dimensional tensors representing samples by features by cell types. Unico stands out as the first principled model-based deconvolution method that is theoretically justified for any heterogeneous genomic data. For more details see Chen and Rahmani et al. (2024) <doi:10.1101/2024.01.27.577588>.
This package provides an overview of the demand for natural gas in the US by state and country level. Data source: US Energy Information Administration <https://www.eia.gov/>.
This package provides an R-based access to the datasets including their resources from the portal <https://umwelt.info>. The package allows for an easy integration of those datasets into your R-based workflows. The functionality of the package mirrors the web-based access as provided at <https://umwelt.info>. You can use the same queries and get the same datasets by accessing our API.
Download and explore datasets from UCSC Xena data hubs, which are a collection of UCSC-hosted public databases such as TCGA, ICGC, TARGET, GTEx, CCLE, and others. Databases are normalized so they can be combined, linked, filtered, explored and downloaded.
Bindings to Uno (Unifying Nonlinear Optimization), a C++ solver for smooth nonlinearly constrained optimization. Uno unifies Lagrange-Newton methods, including sequential quadratic programming and interior-point methods, by decomposing them into interacting building blocks (constraint-relaxation, inequality-handling, Hessian, and globalization strategies) that can be freely combined, either through options or through presets that reproduce established solvers such as filterSQP and IPOPT'. The framework is described in Vanaret and Leyffer (2024) <doi:10.48550/arXiv.2406.13454>.
This package contains a WGS84 datum map of the USA, which includes all Commonwealth and State boundaries & also includes Puerto Rico and the U.S. Virgin Islands. This map is a reprojection of the NAD83 datum map from the USGS National Map. This package contains a subset of the data included in the USA.state.boundaries.data package, which is available in a drat repository. To install that data package, please follow the instructions at <https://gitlab.com/iembry/usa.state.boundaries.data>.
Maximum likelihood estimation of univariate Gaussian Mixture Autoregressive (GMAR), Student's t Mixture Autoregressive (StMAR), and Gaussian and Student's t Mixture Autoregressive (G-StMAR) models, quantile residual tests, graphical diagnostics, forecast and simulate from GMAR, StMAR and G-StMAR processes. Leena Kalliovirta, Mika Meitz, Pentti Saikkonen (2015) <doi:10.1111/jtsa.12108>, Mika Meitz, Daniel Preve, Pentti Saikkonen (2023) <doi:10.1080/03610926.2021.1916531>, Savi Virolainen (2022) <doi:10.1515/snde-2020-0060>.