Generates synonyms from a given word drawing from a synonym list from the moby project <http://moby-thesaurus.org/>.

Explore synesthesia consistency test data, calculate consistency scores, and classify participant data as valid or invalid.

Regression inference for multiple populations by integrating summary-level data using stacked imputations. Gu, T., Taylor, J.M.G. and Mukherjee, B. (2021) A synthetic data integration framework to leverage external summary-level information from heterogeneous populations <arXiv:2106.06835>.

This package implements the synthetic control group method for comparative case studies as described in Abadie and Gardeazabal (2003) and Abadie, Diamond, and Hainmueller (2010, 2011, 2014). The synthetic control method allows for effect estimation in settings where a single unit (a state, country, firm, etc.) is exposed to an event or intervention. It provides a data-driven procedure to construct synthetic control units based on a weighted combination of comparison units that approximates the characteristics of the unit that is exposed to the intervention. A combination of comparison units often provides a better comparison for the unit exposed to the intervention than any comparison unit alone.

There are increasing demands on designing virus mutants with specific dinucleotide or codon composition. This tool can take both dinucleotide preference and/or codon usage bias into account while designing mutants. It is a powerful tool for in silico designs of DNA sequence mutants.

Analysis of metacommunities based on functional traits and phylogeny of the community components. The functions that are offered here implement for the R environment methods that have been available in the SYNCSA application written in C++ (by Valerio Pillar, available at <http://ecoqua.ecologia.ufrgs.br/SYNCSA.html>).

Select hits from synthetic lethal RNAi screen data. For example, there are two identical celllines except one gene is knocked-down in one cellline. The interest is to find genes that lead to stronger lethal effect when they are knocked-down further by siRNA. Quality control and various visualisation tools are implemented. Four different algorithms could be used to pick up the interesting hits. This package is designed based on 384 wells plates, but may apply to other platforms with proper configuration.

Generate the same random numbers in R and Python.

This package provides a set of functions for generating SPSS syntax files from the R environment.

The function syncSubsample subsamples temporal data of different entities so that the result only contains synchronal events. The function mci calculates the Movement Coordination Index (MCI, see reference on help page for function mci') of a data set created with the function syncSubsample'.

The synapter package provides functionality to reanalyse label-free proteomics data acquired on a Synapt G2 mass spectrometer. One or several runs, possibly processed with additional ion mobility separation to increase identification accuracy can be combined to other quantitation files to maximise identification and quantitation accuracy.

syntenet can be used to infer synteny networks from whole-genome protein sequences and analyze them. Anchor pairs are detected with the MCScanX algorithm, which was ported to this package with the Rcpp framework for R and C++ integration. Anchor pairs from synteny analyses are treated as an undirected unweighted graph (i.e., a synteny network), and users can perform: i. network clustering; ii. phylogenomic profiling (by identifying which species contain which clusters) and; iii. microsynteny-based phylogeny reconstruction with maximum likelihood.

Synapsis is a Bioconductor software package for automated (unbiased and reproducible) analysis of meiotic immunofluorescence datasets. The primary functions of the software can i) identify cells in meiotic prophase that are labelled by a synaptonemal complex axis or central element protein, ii) isolate individual synaptonemal complexes and measure their physical length, iii) quantify foci and co-localise them with synaptonemal complexes, iv) measure interference between synaptonemal complex-associated foci. The software has applications that extend to multiple species and to the analysis of other proteins that label meiotic prophase chromosomes. The software converts meiotic immunofluorescence images into R data frames that are compatible with machine learning methods. Given a set of microscopy images of meiotic spread slides, synapsis crops images around individual single cells, counts colocalising foci on strands on a per cell basis, and measures the distance between foci on any given strand.

This package provides a tool for producing synthetic versions of microdata containing confidential information so that they are safe to be released to users for exploratory analysis. The key objective of generating synthetic data is to replace sensitive original values with synthetic ones causing minimal distortion of the statistical information contained in the data set. Variables, which can be categorical or continuous, are synthesised one-by-one using sequential modelling. Replacements are generated by drawing from conditional distributions fitted to the original data using parametric or classification and regression trees models. Data are synthesised via the function syn() which can be largely automated, if default settings are used, or with methods defined by the user. Optional parameters can be used to influence the disclosure risk and the analytical quality of the synthesised data. For a description of the implemented method see Nowok, Raab and Dibben (2016) <doi:10.18637/jss.v074.i11>. Functions to assess identity and attribute disclosure for the original and for the synthetic data are included in the package, and their use is illustrated in a vignette on disclosure (Practical Privacy Metrics for Synthetic Data).

Shared order between genomic sequences provide a great deal of information. Synteny objects produced by the R package DECIPHER provides quantitative information about that shared order. SynExtend provides tools for extracting information from Synteny objects.

This package provides methods for computing spatial, temporal, and spatiotemporal statistics as described in Gouhier and Guichard (2014) <doi:10.1111/2041-210X.12188>. These methods include empirical univariate, bivariate and multivariate variograms; fitting variogram models; phase locking and synchrony analysis; generating autocorrelated and cross-correlated matrices.

Generate synthetic time series from commonly used statistical models, including linear, nonlinear and chaotic systems. Applications to testing methods can be found in Jiang, Z., Sharma, A., & Johnson, F. (2019) <doi:10.1016/j.advwatres.2019.103430> and Jiang, Z., Sharma, A., & Johnson, F. (2020) <doi:10.1029/2019WR026962> associated with an open-source tool by Jiang, Z., Rashid, M. M., Johnson, F., & Sharma, A. (2020) <doi:10.1016/j.envsoft.2020.104907>.

The synchrosqueezed wavelet transform is implemented. The package is a translation of MATLAB Synchrosqueezing Toolbox, version 1.1 originally developed by Eugene Brevdo (2012). The C code for curve_ext was authored by Jianfeng Lu, and translated to Fortran by Dongik Jang. Synchrosqueezing is based on the papers: [1] Daubechies, I., Lu, J. and Wu, H. T. (2011) Synchrosqueezed wavelet transforms: An empirical mode decomposition-like tool. Applied and Computational Harmonic Analysis, 30. 243-261. [2] Thakur, G., Brevdo, E., Fukar, N. S. and Wu, H-T. (2013) The Synchrosqueezing algorithm for time-varying spectral analysis: Robustness properties and new paleoclimate applications. Signal Processing, 93, 1079-1094.

Creation of an individual claims simulator which generates various features of non-life insurance claims. An initial set of test parameters, designed to mirror the experience of an Auto Liability portfolio, were set up and applied by default to generate a realistic test data set of individual claims (see vignette). The simulated data set then allows practitioners to back-test the validity of various reserving models and to prove and/or disprove certain actuarial assumptions made in claims modelling. The distributional assumptions used to generate this data set can be easily modified by users to match their experiences. Reference: Avanzi B, Taylor G, Wang M, Wong B (2020) "SynthETIC: an individual insurance claim simulator with feature control" <arXiv:2008.05693>.

This package provides a critical first step in systematic literature reviews and mining of academic texts is to identify relevant texts from a range of sources, particularly databases such as Web of Science or Scopus'. These databases often export in different formats or with different metadata tags. synthesisr expands on the tools outlined by Westgate (2019) <doi:10.1002/jrsm.1374> to import bibliographic data from a range of formats (such as bibtex', ris', or ciw') in a standard way, and allows merging and deduplication of the resulting dataset.

This package provides a framework for evaluating drug combination effects in preclinical in vivo studies. SynergyLMM provides functions to analyze longitudinal tumor growth experiments using mixed-effects models, perform time-resolved analyses of synergy and antagonism, evaluate model diagnostics and performance, and assess both post-hoc and a priori statistical power. The calculation of drug combination synergy follows the statistical framework provided by Demidenko and Miller (2019, <doi:10.1371/journal.pone.0224137>). The implementation and analysis of linear mixed-effect models is based on the methods described by Pinheiro and Bates (2000, <doi:10.1007/b98882>), and GaÅ ecki and Burzykowski (2013, <doi:10.1007/978-1-4614-3900-4>).

This package provides a set of functions to support experimentation in the utility of partially synthetic data sets. All functions compare an observed data set to one or a set of partially synthetic data sets derived from the observed data to (1) check that data sets have identical attributes, (2) calculate overall and specific variable perturbation rates, (3) check for potential logical inconsistencies, and (4) calculate confidence intervals and standard errors of desired variables in multiple imputed data sets. Confidence interval and standard error formulas have options for either synthetic data sets or multiple imputed data sets. For more information on the formulas and methods used, see Reiter & Raghunathan (2007) <doi:10.1198/016214507000000932>.

This package implements the revised Synthetic Matching Algorithm of Kreitmeir, Lane, and Raschky (2025) <doi:10.2139/ssrn.3751162>, building on the original approach of Acemoglu, Johnson, Kermani, Kwak, and Mitton (2016) <doi:10.1016/j.jfineco.2015.10.001>, to estimate the cumulative treatment effect of an event on treated firmsâ stock returns.

Synthesize numeric, categorical, mixed and time series data. Data circumstances including mixed (or zero-inflated) distributions and missing data patterns are reproduced in the synthetic data. A single parameter allows balancing between high-quality synthetic data that represents correlations of the original data and lower quality but more privacy safe synthetic data without correlations. Tuning can be done per variable or for the whole dataset.