Defines S3 vector data types for vectors of functional data (grid-based, spline-based or functional principal components-based) with all arithmetic and summary methods, derivation, integration and smoothing, plotting, data import and export, and data wrangling, such as re-evaluating, subsetting, sub-assigning, zooming into sub-domains, or extracting functional features like minima/maxima and their locations. The implementation allows including such vectors in data frames for joint analysis of functional and scalar variables.
The Truncated Factor Model is a statistical model designed to handle specific data structures in data analysis. This R package focuses on the Sparse Online Principal Component Estimation method, which is used to calculate data such as the loading matrix and specific variance matrix for truncated data, thereby better explaining the relationship between common factors and original variables. Additionally, the R package also provides other equations for comparison with the Sparse Online Principal Component Estimation method.The philosophy of the package is described in thesis. (2023) <doi:10.1007/s00180-022-01270-z>.
Statistical interpretation of forensic glass transfer (Simulation of the probability distribution of recovered glass fragments).
Interface to TensorFlow
IO', Datasets and filesystem extensions maintained by `TensorFlow
SIG-IO` <https://github.com/tensorflow/community/blob/master/sigs/io/CHARTER.md>.
Provide functions to estimate the coefficients in high-dimensional linear regressions via a tuning-free and robust approach. The method was published in Wang, L., Peng, B., Bradic, J., Li, R. and Wu, Y. (2020), "A Tuning-free Robust and Efficient Approach to High-dimensional Regression", Journal of the American Statistical Association, 115:532, 1700-1714(JASAâ s discussion paper), <doi:10.1080/01621459.2020.1840989>. See also Wang, L., Peng, B., Bradic, J., Li, R. and Wu, Y. (2020), "Rejoinder to â A tuning-free robust and efficient approach to high-dimensional regression". Journal of the American Statistical Association, 115, 1726-1729, <doi:10.1080/01621459.2020.1843865>; Peng, B. and Wang, L. (2015), "An Iterative Coordinate Descent Algorithm for High-Dimensional Nonconvex Penalized Quantile Regression", Journal of Computational and Graphical Statistics, 24:3, 676-694, <doi:10.1080/10618600.2014.913516>; Clémençon, S., Colin, I., and Bellet, A. (2016), "Scaling-up empirical risk minimization: optimization of incomplete u-statistics", The Journal of Machine Learning Research, 17(1):2682â 2717; Fan, J. and Li, R. (2001), "Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties", Journal of the American Statistical Association, 96:456, 1348-1360, <doi:10.1198/016214501753382273>.
It searches for relevant associations of transcription factors with a transcription factor target, in specific genomic regions. It also allows to evaluate the Importance Index distribution of transcription factors (and combinations of transcription factors) in association rules.
This package creates a framework to store and apply display metadata to Analysis Results Datasets (ARDs). The use of tfrmt allows users to define table format and styling without the data, and later apply the format to the data.
In Cox's proportional hazard model, covariates are modeled as linear function and may not be flexible. This package implements additive trend filtering Cox proportional hazards model as proposed in Jiacheng Wu & Daniela Witten (2019) "Flexible and Interpretable Models for Survival Data", Journal of Computational and Graphical Statistics, <DOI:10.1080/10618600.2019.1592758>. The fitted functions are piecewise polynomial with adaptively chosen knots.
TensorFlow
Hub is a library for the publication, discovery, and consumption of reusable parts of machine learning models. A module is a self-contained piece of a TensorFlow
graph, along with its weights and assets, that can be reused across different tasks in a process known as transfer learning. Transfer learning train a model with a smaller dataset, improve generalization, and speed up training.
It finds trascription factor (TF) high accumulation DNA zones, i.e., regions along the genome where there is a high presence of different transcription factors. Starting from a dataset containing the genomic positions of TF binding regions, for each base of the selected chromosome the accumulation of TFs is computed. Three different types of accumulation (TF, region and base accumulation) are available, together with the possibility of considering, in the single base accumulation computing, the TFs present not only in that single base, but also in its neighborhood, within a window of a given width. Two different methods for the search of TF high accumulation DNA zones, called "binding regions" and "overlaps", are available. In addition, some functions are provided in order to analyze, visualize and compare results obtained with different input parameters.
Create and manage unique directories for each TensorFlow training run. This package provides a unique, time stamped directory for each run along with functions to retrieve the directory of the latest run or latest several runs.
Utilities for simple manipulation and quick plotting of time series data. These utilities use the tframe package which provides a programming kernel for time series. Extensions to tframe provided in tframePlus
can also be used. See the Guide vignette for examples.
This package provides a kernel of functions for programming time series methods in a way that is relatively independently of the representation of time. Also provides plotting, time windowing, and some other utility functions which are specifically intended for time series. See the Guide distributed as a vignette, or ?tframe.Intro for more details. (User utilities are in package tfplot.).
This package helps users to work with TF metadata from various sources. Significant catalogs of TFs and classifications thereof are made available. Tools for working with motif scans are also provided.
This package provides the cumulative distribution function (CDF), quantile, and statistical power calculator for a collection of thresholding Fisher's p-value combination methods, including Fisher's p-value combination method, truncated product method and, in particular, soft-thresholding Fisher's p-value combination method which is proven to be optimal in some context of signal detection. The p-value calculator for the omnibus version of these tests are also included.
Building customized transfer function and ARIMA models with multiple operators and parameter restrictions. Functions for model identification, model estimation (exact or conditional maximum likelihood), model diagnostic checking, automatic outlier detection, calendar effects, forecasting and seasonal adjustment. See Bell and Hillmer (1983) <doi:10.1080/01621459.1983.10478005>, Box, Jenkins, Reinsel and Ljung <ISBN:978-1-118-67502-1>, Box, Pierce and Newbold (1987) <doi:10.1080/01621459.1987.10478430>, Box and Tiao (1975) <doi:10.1080/01621459.1975.10480264>, Chen and Liu (1993) <doi:10.1080/01621459.1993.10594321>.
R implementation of TFactS
to predict which are the transcription factors (TFs), regulated in a biological condition based on lists of differentially expressed genes (DEGs) obtained from transcriptome experiments. This package is based on the TFactS
concept by Essaghir et al. (2010) <doi:10.1093/nar/gkq149> and expands it. It allows users to perform TFactS'-like
enrichment approach. The package can import and use the original catalogue file from the TFactS
as well as users defined catalogues of interest that are not supported by TFactS
(e.g., Arabidopsis).
This package provides tools to deploy TensorFlow
<https://www.tensorflow.org/> models across multiple services. Currently, it provides a local server for testing cloudml compatible services.
This package provides a convenient way to log scalars, images, audio, and histograms in the tfevent record file format. Logged data can be visualized on the fly using TensorBoard
', a web based tool that focuses on visualizing the training progress of machine learning models.
Extension of funHDDC
Schmutz et al. (2018) <doi:10.1007/s00180-020-00958-4> for cases including outliers by fitting t-distributions for robust groups. TFunHDDC
can cluster univariate or multivariate data produced by the fda package for data using a b-splines or Fourier basis.
TensorFlow
SIG Addons <https://www.tensorflow.org/addons> is a repository of community contributions that conform to well-established API patterns, but implement new functionality not available in core TensorFlow
'. TensorFlow
natively supports a large number of operators, layers, metrics, losses, optimizers, and more. However, in a fast moving field like Machine Learning, there are many interesting new developments that cannot be integrated into core TensorFlow
(because their broad applicability is not yet clear, or it is mostly used by a smaller subset of the community).
Package to analize transcription factor enrichment in a gene set using data from ChIP-Seq
experiments.
TFBSTools is a package for the analysis and manipulation of transcription factor binding sites. It includes matrices conversion between Position Frequency Matrix (PFM), Position Weight Matrix (PWM) and Information Content Matrix (ICM). It can also scan putative TFBS from sequence/alignment, query JASPAR database and provides a wrapper of de novo motif discovery software.
In putative Transcription Factor Binding Sites (TFBSs) identification from sequence/alignments, we are interested in the significance of certain match scores. TFMPvalue provides the accurate calculation of a p-value with a score threshold for position weight matrices, or the score with a given p-value. It is an interface to code originally made available by Helene Touzet and Jean-Stephane Varre, 2007, Algorithms Mol Biol:2, 15. Touzet and Varre (2007).