SPsimSeq uses a specially designed exponential family for density estimation to constructs the distribution of gene expression levels from a given real RNA sequencing data (single-cell or bulk), and subsequently simulates a new dataset from the estimated marginal distributions using Gaussian-copulas to retain the dependence between genes. It allows simulation of multiple groups and batches with any required sample size and library size.

This is an R package for spell checking common document formats including LaTeX, markdown, manual pages, and DESCRIPTION files. It includes utilities to automate checking of documentation and vignettes as a unit test during R CMD check. Both British and American English are supported out of the box and other languages can be added. In addition, packages may define a wordlist to allow custom terminology without having to abuse punctuation.

This package provides functions to compute split generalized linear models. The approach fits generalized linear models that split the covariates into groups. The optimal split of the variables into groups and the regularized estimation of the coefficients are performed by minimizing an objective function that encourages sparsity within each group and diversity among them. Example applications can be found in Christidis et al. (2021) <doi:10.48550/arXiv.2102.08591>.

Statistical pattern recognition and dating using archaeological artefacts assemblages. Package of statistical tools for archaeology. hclustcompro()/perioclust(): Bellanger Lise, Coulon Arthur, Husi Philippe (2021, ISBN:978-3-030-60103-4). mapclust(): Bellanger Lise, Coulon Arthur, Husi Philippe (2021) <doi:10.1016/j.jas.2021.105431>. seriograph(): Desachy Bruno (2004) <doi:10.3406/pica.2004.2396>. cerardat(): Bellanger Lise, Husi Philippe (2012) <doi:10.1016/j.jas.2011.06.031>.

This package provides interface to sparsepp - fast, memory efficient hash map. It is derived from Google's excellent sparsehash implementation. We believe sparsepp provides an unparalleled combination of performance and memory usage, and will outperform your compiler's unordered_map on both counts. Only Google's dense_hash_map is consistently faster, at the cost of much greater memory usage (especially when the final size of the map is not known in advance).

This package provides a spatio-dynamic modelling package that focuses on three characteristic wetland plant communities in a semiarid Mediterranean wetland in response to hydrological pressures from the catchment. The package includes the data on watershed hydrological pressure and the initial raster maps of plant communities but also allows for random initial distribution of plant communities. For more detailed info see: Martinez-Lopez et al. (2015) <doi:10.1016/j.ecolmodel.2014.11.024>.

This package implements the Smoothness-Penalized Deconvolution method for estimating a probability density under measurement error of Kent and Ruppert (2023) <doi:10.1080/01621459.2023.2259028>. The estimator is formed by computing a histogram of the error-contaminated data, and then finding an estimate that minimizes a reconstruction error plus a smoothness-inducing penalty term. The primary function, sped(), takes the data and error distribution, and returns the estimator as a function.

On discrete data spectral analysis is performed by Fourier and Hilbert transforms as well as with model based analysis called Lomb-Scargle method. Fragmented and irregularly spaced data can be processed in almost all methods. Both, FFT as well as LOMB methods take multivariate data and return standardized PSD. For didactic reasons an analytical approach for deconvolution of noise spectra and sampling function is provided. A user friendly interface helps to interpret the results.

This package provides a novel spatial topic model to integrate both cell type and spatial information to identify the complex spatial tissue architecture on multiplexed tissue images without human intervention. The Package implements a collapsed Gibbs sampling algorithm for inference. The method is highly scalable to large-scale image datasets without extracting neighborhood information for every single cell. The package supports spatially resolved cell-level data analysis, topic inference, visualization, and downstream biological interpretation of tissue microenvironments.

Efficient implementation of sparse group lasso with optional bound constraints on the coefficients; see <doi:10.18637/jss.v110.i06>. It supports the use of a sparse design matrix as well as returning coefficient estimates in a sparse matrix. Furthermore, it correctly calculates the degrees of freedom to allow for information criteria rather than cross-validation with very large data. Finally, the interface to compiled code avoids unnecessary copies and allows for the use of long integers.

Fitting dimension reduction methods to data lying on two-dimensional sphere. This package provides principal geodesic analysis, principal circle, principal curves proposed by Hauberg, and spherical principal curves. Moreover, it offers the method of locally defined principal geodesics which is underway. The detailed procedures are described in Lee, J., Kim, J.-H. and Oh, H.-S. (2021) <doi:10.1109/TPAMI.2020.3025327>. Also see Kim, J.-H., Lee, J. and Oh, H.-S. (2020) <arXiv:2003.02578>.

This package provides functions for computing split regularized estimators defined in Christidis, Lakshmanan, Smucler and Zamar (2019) <doi:10.48550/arXiv.1712.03561>. The approach fits linear regression models that split the set of covariates into groups. The optimal split of the variables into groups and the regularized estimation of the regression coefficients are performed by minimizing an objective function that encourages sparsity within each group and diversity among them. The estimated coefficients are then pooled together to form the final fit.

This package provides a set of RStudio addins that are designed to be used in combination with user-defined RStudio keyboard shortcuts. These addins either: 1) insert text at a cursor position (e.g. insert operators %>%, <<-, %$%, etc.), 2) replace symbols in selected pieces of text (e.g., convert backslashes to forward slashes which results in stings like "c:\data\" converted into "c:/data/") or 3) enclose text with special symbols (e.g., converts "bold" into "**bold**") which is convenient for editing R Markdown files.

This package provides a comprehensive toolbox for analysing Spatial Point Patterns. It is focused mainly on two-dimensional point patterns, including multitype/marked points, in any spatial region. It also supports three-dimensional point patterns, space-time point patterns in any number of dimensions, point patterns on a linear network, and patterns of other geometrical objects. It supports spatial covariate data such as pixel images and contains over 2000 functions for plotting spatial data, exploratory data analysis, model-fitting, simulation, spatial sampling, model diagnostics, and formal inference.

This package provides a self-tuning spectral clustering method for single or multi-view data. Spectrum uses a new type of adaptive density aware kernel that strengthens connections in the graph based on common nearest neighbours. It uses a tensor product graph data integration and diffusion procedure to integrate different data sources and reduce noise. Spectrum uses either the eigengap or multimodality gap heuristics to determine the number of clusters. The method is sufficiently flexible so that a wide range of Gaussian and non-Gaussian structures can be clustered with automatic selection of K.

This package provides a spline based scRNA-seq method for identifying differentially variable (DV) genes across two experimental conditions. Spline-DV constructs a 3D spline from 3 key gene statistics: mean expression, coefficient of variance, and dropout rate. This is done for both conditions. The 3D spline provides the “expected” behavior of genes in each condition. The distance of the observed mean, CV and dropout rate of each gene from the expected 3D spline is used to measure variability. As the final step, the spline-DV method compares the variabilities of each condition to identify differentially variable (DV) genes.

This package implements variational Bayesian algorithms to perform scalable variable selection for sparse, high-dimensional linear and logistic regression models. Features include a novel prioritized updating scheme, which uses a preliminary estimator of the variational means during initialization to generate an updating order prioritizing large, more relevant, coefficients. Sparsity is induced via spike-and-slab priors with either Laplace or Gaussian slabs. By default, the heavier-tailed Laplace density is used. Formal derivations of the algorithms and asymptotic consistency results may be found in Kolyan Ray and Botond Szabo (JASA 2020) and Kolyan Ray, Botond Szabo, and Gabriel Clara (NeurIPS 2020).

Recently, regularized variable selection has emerged as a powerful tool to identify and dissect gene-environment interactions. Nevertheless, in longitudinal studies with high dimensional genetic factors, regularization methods for GÃ E interactions have not been systematically developed. In this package, we provide the implementation of sparse group variable selection, based on both the quadratic inference function (QIF) and generalized estimating equation (GEE), to accommodate the bi-level selection for longitudinal GÃ E studies with high dimensional genomic features. Alternative methods conducting only the group or individual level selection have also been included. The core modules of the package have been developed in C++.

This package provides an R interface to the sparseLM C library for large-scale nonlinear least squares problems with arbitrarily sparse Jacobians. The underlying solver implements a sparse variant of the Levenberg-Marquardt algorithm for minimizing sum-of-squares objective functions, supports user-supplied analytic Jacobians or finite-difference approximation, and is designed to exploit sparsity for improved memory use and performance. This package exposes the solver in R and uses sparse matrix classes and the CHOLMOD sparse Cholesky factorization routines through the Matrix package interface. Methods from the C library are described in Lourakis (2010) <doi:10.1007/978-3-642-15552-9_4>.

Contemporary software commonly used to design stated preference experiments are expensive and the code is closed source. This is a free software package with an easy to use interface to make flexible stated preference experimental designs using state-of-the-art methods. For an overview of stated choice experimental design theory, see e.g., Rose, J. M. & Bliemer, M. C. J. (2014) in Hess S. & Daly. A. <doi:10.4337/9781781003152>. The package website can be accessed at <https://spdesign.edsandorf.me>. We acknowledge funding from the European Unionâ s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant INSPiRE (Grant agreement ID: 793163).

Data visualization tours animates linear projection of multivariate data as its basis (ie. orientation) changes. The spinifex packages generates paths for manual tours by manipulating the contribution of a single variable at a time Cook & Buja (1997) <doi:10.1080/10618600.1997.10474754>. Other types of tours, such as grand (random walk) and guided (optimizing some objective function) are available in the tourr package Wickham et al. <doi:10.18637/jss.v040.i02>. spinifex builds on tourr and can render tours with gganimate and plotly graphics, and allows for exporting as an .html widget and as an .gif, respectively. This work is fully discussed in Spyrison & Cook (2020) <doi:10.32614/RJ-2020-027>.

This package implements the algorithm described in Barron, M., Zhang, S. and Li, J. 2017, "A sparse differential clustering algorithm for tracing cell type changes via single-cell RNA-sequencing data", Nucleic Acids Research, gkx1113, <doi:10.1093/nar/gkx1113>. This algorithm clusters samples from two different populations, links the clusters across the conditions and identifies marker genes for these changes. The package was designed for scRNA-Seq data but is also applicable to many other data types, just replace cells with samples and genes with variables. The package also contains functions for estimating the parameters for SparseDC as outlined in the paper. We recommend that users further select their marker genes using the magnitude of the cluster centers.

This package implements the Stratigraphic Plug Alignment (SPA) procedure for integrating sparsely sampled plug-based measurements (e.g., total organic carbon, porosity, mineralogy) with high-resolution X-ray fluorescence (XRF) geochemical data. SPA uses linear interpolation via the base approx() function with constrained extrapolation (rule = 1) to preserve stratigraphic order and avoid estimation beyond observed depths. The method aligns all datasets to a common depth grid, enabling high-resolution multivariate analysis and stratigraphic interpretation of core-based datasets such as those from the Utica and Point Pleasant formations. See R Core Team (2025) <https://stat.ethz.ch/R-manual/R-devel/library/stats/html/stats-package.html> and Omodolor (2025) <http://rave.ohiolink.edu/etdc/view?acc_num=case175262671767524> for methodological background and geological context.

Analyse light spectra for visual and non-visual (often called melanopic) needs, wrapped up in a Shiny App. Spectran allows for the import of spectra in various CSV forms but also provides a wide range of example spectra and even the creation of own spectral power distributions. The goal of the app is to provide easy access and a visual overview of the spectral calculations underlying common parameters used in the field. It is thus ideal for educational purposes or the creation of presentation ready graphs in lighting research and application. Spectran uses equations and action spectra described in CIE S026 (2018) <doi:10.25039/S026.2018>, DIN/TS 5031-100 (2021) <doi:10.31030/3287213>, and ISO/CIE 23539 (2023) <doi:10.25039/IS0.CIE.23539.2023>.