Allows practitioners and researchers a wholesale approach for deriving magnitude-based inferences from raw data. A major goal of mbir is to programmatically detect appropriate statistical tests to run in lieu of relying on practitioners to determine correct stepwise procedures independently.

Efficient procedures for computing a new Multi-Class Sparse Discriminant Analysis method that estimates all discriminant directions simultaneously. It is an implementation of the work proposed by Mai, Q., Yang, Y., and Zou, H. (2019) <doi:10.5705/ss.202016.0117>.

This package provides a novel mediation analysis approach to address zero-inflated mediators containing true zeros and false zeros. See Jiang et al (2023) "A Novel Causal Mediation Analysis Approach for Zero-Inflated Mediators" <arXiv:2301.10064> for more details.

Estimation, inference and diagnostics for Univariate Autoregressive Markov Switching Models for Linear and Generalized Models. Distributions for the series include gaussian, Poisson, binomial and gamma cases. The EM algorithm is used for estimation (see Perlin (2012) <doi:10.2139/ssrn.1714016>).

Fits the Multivariate Cluster Elastic Net (MCEN) presented in Price & Sherwood (2018) <arXiv:1707.03530>. The MCEN model simultaneously estimates regression coefficients and a clustering of the responses for a multivariate response model. Currently accommodates the Gaussian and binomial likelihood.

Package to select best model among several linear and nonlinear models. The main function uses the gnls() function from the nlme package to fit the data to nine regression models, named: "linear", "quadratic", "cubic", "logistic", "exponential", "power", "monod", "haldane", "logit".

Computes the pdf, cdf, quantile function, hazard function and generating random numbers for Odd log-logistic family (OLL-G). This family have been developed by different authors in the recent years. See Alizadeh (2019) <doi:10.31801/cfsuasmas.542988> for example.

Estimating parameters of site clusters on 2D & 3D square lattice with various lattice sizes, relative fractions of open sites (occupation probability), iso- & anisotropy, von Neumann & Moore (1,d)-neighborhoods, described by Moskalev P.V. et al. (2011) <arXiv:1105.2334v1>.

Efficient procedure for solving the soft maximin problem for large scale heterogeneous data, see Lund, Mogensen and Hansen (2022) <doi:10.1111/sjos.12580>. Currently Lasso and SCAD penalized estimation is implemented. Note this package subsumes and replaces the SMMA package.

This package provides a collection of functions for visualizing,exploring and annotating genetic association results.Association results from multiple traits can be viewed simultaneously along with gene annotation, over the entire genome (Manhattan plot) or in the more detailed regional view.

The tinytest package offers a light-weight zero-dependency unit-testing framework to which this package adds support via the diffobj package for diff'-style textual comparison of R objects, as well as via tinysnapshot package for visual differences in plots.

This package provides functions that can be used to calculate time-dependent state and parameter sensitivities for both continuous- and discrete-time deterministic models. See Ng et al. (2023) <doi:10.1086/726143> for more information about time-dependent sensitivity analysis.

The purpose of this package is to provide methods to interpret multiple linear regression and canonical correlation results including beta weights,structure coefficients, validity coefficients, product measures, relative weights, all-possible-subsets regression, dominance analysis, commonality analysis, and adjusted effect sizes.

This package provides a two-part zero-inflated Beta regression model with random effects (ZIBR) for testing the association between microbial abundance and clinical covariates for longitudinal microbiome data. Eric Z. Chen and Hongzhe Li (2016) <doi:10.1093/bioinformatics/btw308>.

This package provides several methods for performing permutation tests. It has three main functions, to perform linear permutation tests. These tests are tests where the test statistic is the sum of the product of a covariate (usually group indicator) and the scores.

This package lets you calculate power for generalized linear mixed models, using simulation. It was designed to work with models fit using the lme4 package. The package is described in Green and MacLeod (2016).

Efficient framework for ridge redundancy analysis (rrda), tailored for high-dimensional omics datasets where the number of predictors exceeds the number of samples. The method leverages Singular Value Decomposition (SVD) to avoid direct inversion of the covariance matrix, enhancing scalability and performance. It also introduces a memory-efficient storage strategy for coefficient matrices, enabling practical use in large-scale applications. The package supports cross-validation for selecting regularization parameters and reduced-rank dimensions, making it a robust and flexible tool for multivariate analysis in omics research. Please refer to our article (Yoshioka et al., 2025) for more details.

The Rcpp package provides R functions as well as C++ classes which offer a seamless integration of R and C++. Many R data types and objects can be mapped back and forth to C++ equivalents which facilitates both writing of new code as well as easier integration of third-party libraries. Documentation about Rcpp is provided by several vignettes included in this package, via the Rcpp Gallery site at <http://gallery.rcpp.org>, the paper by Eddelbuettel and Francois (2011, JSS), and the book by Eddelbuettel (2013, Springer); see citation("Rcpp") for details on these last two.

Utility functions that provides wrapper to descriptive base functions like cor, mean and table. It makes use of the formula interface to pass variables to functions. It also provides operators to concatenate (%+%), to repeat (%n%) and manage character vectors for nice display.

Simulating multi-arm cluster-randomized, multi-site, and simple randomized trials. Includes functions for conducting multilevel analyses using both Bayesian and Frequentist methods. Supports futility and superiority analyses through Bayesian approaches, along with visualization tools to aid interpretation and presentation of results.

This package provides a GraphQL client, with an R6 interface for initializing a connection to a GraphQL instance, and methods for constructing queries, including fragments and parameterized queries. Queries are checked with the libgraphqlparser C++ parser via the gaphql package.

Build Open Geospatial Consortium GeoPackage files (<https://www.geopackage.org/>). GDAL utilities for reading and writing spatial data are provided by the terra package. Additional GeoPackage and SQLite features for attributes and tabular data are implemented with the RSQLite package.

Calculate expected relative risk and proportion protected assuming normally distributed log10 transformed antibody dose for a several component vaccine. Uses Hill models for each component which are combined under Bliss independence. See Saul and Fay, 2007 <DOI:10.1371/journal.pone.0000850>.

Hierarchical Modelling of Species Communities (HMSC) is a model-based approach for analyzing community ecological data. This package implements it in the Bayesian framework with Gibbs Markov chain Monte Carlo (MCMC) sampling (Tikhonov et al. (2020) <doi:10.1111/2041-210X.13345>).