Statistical methods for the modeling and monitoring of time series of counts, proportions and categorical data, as well as for the modeling of continuous-time point processes of epidemic phenomena. The monitoring methods focus on aberration detection in count data time series from public health surveillance of communicable diseases, but applications could just as well originate from environmetrics, reliability engineering, econometrics, or social sciences. The package implements many typical outbreak detection procedures such as the (improved) Farrington algorithm, or the negative binomial GLR-CUSUM method of Hoehle and Paul (2008) <doi:10.1016/j.csda.2008.02.015>. A novel CUSUM approach combining logistic and multinomial logistic modeling is also included. The package contains several real-world data sets, the ability to simulate outbreak data, and to visualize the results of the monitoring in a temporal, spatial or spatio-temporal fashion. A recent overview of the available monitoring procedures is given by Salmon et al. (2016) <doi:10.18637/jss.v070.i10>. For the retrospective analysis of epidemic spread, the package provides three endemic-epidemic modeling frameworks with tools for visualization, likelihood inference, and simulation. hhh4() estimates models for (multivariate) count time series following Paul and Held (2011) <doi:10.1002/sim.4177> and Meyer and Held (2014) <doi:10.1214/14-AOAS743>. twinSIR() models the susceptible-infectious-recovered (SIR) event history of a fixed population, e.g, epidemics across farms or networks, as a multivariate point process as proposed by Hoehle (2009) <doi:10.1002/bimj.200900050>. twinstim() estimates self-exciting point process models for a spatio-temporal point pattern of infective events, e.g., time-stamped geo-referenced surveillance data, as proposed by Meyer et al. (2012) <doi:10.1111/j.1541-0420.2011.01684.x>. A recent overview of the implemented space-time modeling frameworks for epidemic phenomena is given by Meyer et al. (2017) <doi:10.18637/jss.v077.i11>.

Algorithms for checking the accuracy of a clustering result with known classes, computing cluster validity indices, and generating plots for comparing them. The package is compatible with K-means, fuzzy C means, EM clustering, and hierarchical clustering (single, average, and complete linkage). The details of the indices in this package can be found in: J. C. Bezdek, M. Moshtaghi, T. Runkler, C. Leckie (2016) <doi:10.1109/TFUZZ.2016.2540063>, T. Calinski, J. Harabasz (1974) <doi:10.1080/03610927408827101>, C. H. Chou, M. C. Su, E. Lai (2004) <doi:10.1007/s10044-004-0218-1>, D. L. Davies, D. W. Bouldin (1979) <doi:10.1109/TPAMI.1979.4766909>, J. C. Dunn (1973) <doi:10.1080/01969727308546046>, F. Haouas, Z. Ben Dhiaf, A. Hammouda, B. Solaiman (2017) <doi:10.1109/FUZZ-IEEE.2017.8015651>, M. Kim, R. S. Ramakrishna (2005) <doi:10.1016/j.patrec.2005.04.007>, S. H. Kwon (1998) <doi:10.1049/EL:19981523>, S. H. Kwon, J. Kim, S. H. Son (2021) <doi:10.1049/ell2.12249>, G. W. Miligan (1980) <doi:10.1007/BF02293907>, M. K. Pakhira, S. Bandyopadhyay, U. Maulik (2004) <doi:10.1016/j.patcog.2003.06.005>, M. Popescu, J. C. Bezdek, T. C. Havens, J. M. Keller (2013) <doi:10.1109/TSMCB.2012.2205679>, S. Saitta, B. Raphael, I. Smith (2007) <doi:10.1007/978-3-540-73499-4_14>, A. Starczewski (2017) <doi:10.1007/s10044-015-0525-8>, Y. Tang, F. Sun, Z. Sun (2005) <doi:10.1109/ACC.2005.1470111>, N. Wiroonsri (2024) <doi:10.1016/j.patcog.2023.109910>, N. Wiroonsri, O. Preedasawakul (2023) <doi:10.48550/arXiv.2308.14785>, C. H. Wu, C. S. Ouyang, L. W. Chen, L. W. Lu (2015) <doi:10.1109/TFUZZ.2014.2322495>, X. Xie, G. Beni (1991) <doi:10.1109/34.85677> and Rousseeuw (1987) and Kaufman and Rousseeuw(2009) <doi:10.1016/0377-0427(87)90125-7> and <doi:10.1002/9780470316801> C. Alok. (2010).

Descriptive Statistics is essential for publishing articles. This package can perform descriptive statistics according to different data types. If the data is a continuous variable, the mean and standard deviation or median and quartiles are automatically output; if the data is a categorical variable, the number and percentage are automatically output. In addition, if you enter two variables in this package, the two variables will be described and their relationships will be tested automatically according to their data types. For example, if one of the two input variables is a categorical variable, another variable will be described hierarchically based on the categorical variable and the statistical differences between different groups will be compared using appropriate statistical methods. And for groups of more than two, the post hoc test will be applied. For more information on the methods we used, please see the following references: Libiseller, C. and Grimvall, A. (2002) <doi:10.1002/env.507>, Patefield, W. M. (1981) <doi:10.2307/2346669>, Hope, A. C. A. (1968) <doi:10.1111/J.2517-6161.1968.TB00759.X>, Mehta, C. R. and Patel, N. R. (1983) <doi:10.1080/01621459.1983.10477989>, Mehta, C. R. and Patel, N. R. (1986) <doi:10.1145/6497.214326>, Clarkson, D. B., Fan, Y. and Joe, H. (1993) <doi:10.1145/168173.168412>, Cochran, W. G. (1954) <doi:10.2307/3001616>, Armitage, P. (1955) <doi:10.2307/3001775>, Szabo, A. (2016) <doi:10.1080/00031305.2017.1407823>, David, F. B. (1972) <doi:10.1080/01621459.1972.10481279>, Joanes, D. N. and Gill, C. A. (1998) <doi:10.1111/1467-9884.00122>, Dunn, O. J. (1964) <doi:10.1080/00401706.1964.10490181>, Copenhaver, M. D. and Holland, B. S. (1988) <doi:10.1080/00949658808811082>, Chambers, J. M., Freeny, A. and Heiberger, R. M. (1992) <doi:10.1201/9780203738535-5>, Shaffer, J. P. (1995) <doi:10.1146/annurev.ps.46.020195.003021>, Myles, H. and Douglas, A. W. (1973) <doi:10.2307/2063815>, Rahman, M. and Tiwari, R. (2012) <doi:10.4236/health.2012.410139>, Thode, H. J. (2002) <doi:10.1201/9780203910894>, Jonckheere, A. R. (1954) <doi:10.2307/2333011>, Terpstra, T. J. (1952) <doi:10.1016/S1385-7258(52)50043-X>.

The data that is generated from independent and consecutive GillespieSSA runs for a generic biochemical network is formatted as rows and constitutes an observation. The first column of each row is the computed timestep for each run. Subsequent columns are used for the number of molecules of each participating molecular species or "metabolite" of a generic biochemical network. In this way TemporalGSSA', is a wrapper for the R-package GillespieSSA'. The number of observations must be at least 30. This will generate data that is statistically significant. TemporalGSSA', transforms this raw data into a simulation time-dependent and metabolite-specific trial. Each such trial is defined as a set of linear models (n >= 30) between a timestep and number of molecules for a metabolite. Each linear model is characterized by coefficients such as the slope, arbitrary constant, etc. The user must enter an integer from 1-4. These specify the statistical modality utilized to compute a representative timestep (mean, median, random, all). These arguments are mandatory and will be checked. Whilst, the numeric indicator "0" indicates suitability, "1" prompts the user to revise and re-enter their data. An optional logical argument controls the output to the console with the default being "TRUE" (curtailed) whilst "FALSE" (verbose). The coefficients of each linear model are averaged (mean slope, mean constant) and are incorporated into a metabolite-specific linear regression model as the dependent variable. The independent variable is the representative timestep chosen previously. The generated data is the imputed molecule number for an in silico experiment with (n >=30) observations. These steps can be replicated with multiple set of observations. The generated "technical replicates" can be statistically evaluated (mean, standard deviation) and will constitute simulation time-dependent molecules for each metabolite. For SSA-generated datasets with varying simulation times TemporalGSSA will generate a simulation time-dependent trajectory for each metabolite of the biochemical network under study. The relevant publication with the mathematical derivation of the algorithm is (2022, Journal of Bioinformatics and Computational Biology) <doi:10.1142/S0219720022500184>. The algorithm has been deployed in the following publications (2021, Heliyon) <doi:10.1016/j.heliyon.2021.e07466> and (2016, Journal of Theoretical Biology) <doi:10.1016/j.jtbi.2016.07.002>.

The main goal of the R package treeDbalance is to provide functions for the computation of several measurements of 3D node imbalance and their respective 3D tree imbalance indices, as well as to introduce the new phylo3D format for rooted 3D tree objects. Moreover, it encompasses an example dataset of 3D models of 63 beans in phylo3D format. Please note that this R package was developed alongside the project described in the manuscript Measuring 3D tree imbalance of plant models using graph-theoretical approaches by M. Fischer, S. Kersting, and L. Kühn (2023) <doi:10.48550/arXiv.2307.14537>, which provides precise mathematical definitions of the measurements. Furthermore, the package contains several helpful functions, for example, some auxiliary functions for computing the ancestors, descendants, and depths of the nodes, which ensures that the computations can be done in linear time, or functions that convert existing formats of 3D tree models of other software into the phylo3D format. Moreover, it comprises functions to extract the graph-theoretical topology without vertices of in- and out-degree 1 of rooted 3D trees as well as to adapt node enumerations to the common phylo format. Most functions of treeDbalance require as input a rooted tree in the phylo3D format, an extended phylo format (as introduced in the R package ape 1.9 in November 2006). Such a phylo3D object must have at least two new attributes next to those required by the phylo format: node.coord', the coordinates of the nodes, as well as edge.weight', the literal weight or volume of the edges. Optional attributes are edge.diam', the diameter of the edges, and edge.length', the length of the edges. For visualization purposes one can also specify edge.type', which ranges from normal cylinder to bud to leaf, as well as edge.color to change the color of the edge depiction. This project was supported by the joint research project DIG-IT! funded by the European Social Fund (ESF), reference: ESF/14-BM-A55-0017/19, and the Ministry of Education, Science and Culture of Mecklenburg-Western Pomerania, Germany, as well as by the project ArtIGROW, which is a part of the WIR!-Alliance ArtIFARM â Artificial Intelligence in Farming funded by the German Federal Ministry of Education and Research (FKZ: 03WIR4805).

Crop production systems are increasingly challenged by climate variability, resource limitations, and bioticâ abiotic stresses. In this context, stress tolerance indices and physiological trait estimators are essential tools to identify stable and superior genotypes, quantify yield stability under stress versus non-stress conditions, and understand plant adaptive responses. The PhysioIndexR package provides a unified framework to compute commonly used stress indices, physiological traits, and derived metrics that are critical in crop improvement, crop physiology, and other agricultural sciences. The package includes functions to calculate classical stress tolerance indices (See Lamba et al., 2023; <doi:10.1038/s41598-023-37634-8>) such as Tolerance (TOL), Stress Tolerance Index (STI), Stress Susceptibility Percentage Index (SSPI), Yield Index (YI), Yield Stability Index (YSI), Relative Stress Index (RSI), Mean Productivity (MP), Geometric Mean Productivity (GMP), Harmonic Mean (HM), Mean Relative Performance (MRP), and Percent Yield Reduction (PYR), along with a convenience wrapper all_indices() that returns all indices simultaneously. The function mfvst_from_indices() integrates these indices into a composite stress score using direction-aware membership values (0â 1 scaling) and also averaging, facilitating genotype ranking and selection (See Vinu et al., 2025; <doi:10.1007/s12355-025-01595-1>). The package also implements two novel composite functions: WMFVST(), which computes the Weighted Mean Membership Function Value for Stress Tolerance, and WASI(), which computes the Weighted Average Stress Index, both derived from membership function values (MFV) and raw stress index values, respectively. Beyond stress indices, the package provides functions for key physiological traits relevant to sugarcane and other crops: bmap() computes biomass accumulation and partitioning between leaf, cane/shoot, and root fractions. chl() estimates total chlorophyll content from Soil-Plant Analysis Development (SPAD) and Chlorophyll Content Index (CCI) values using validated quadratic models particularly for sugarcane (See Krishnapriya et al., 2020; <doi:10.37580/JSR.2019.2.9.150-163>). ctd() calculates canopy temperature depression (CTD) from ambient and canopy temperatures, an important indicator of transpiration efficiency. growth() computes key growth analysis parameters, including Leaf Area Index (LAI), Net Assimilation Rate (NAR), and Crop Growth Rate (CGR) across crop growth stages (See Watson, 1958; <doi:10.1093/oxfordjournals.aob.a083596>). ranking() provides flexible ranking utilities for genotype performance with multiple tie-handling and NA-placement options. Through these tools, the package enables researchers to: (i) quantify crop responses to stress environments, (ii) partition physiological components of yield, (iii) integrate multiple indices into composite metrics for genotype evaluation, and (iv) facilitate informed decision making in breeding pipelines, and plant physiology experiments. By combining physiology-based traits with quantitative stress indices, PhysioIndexR supports comprehensive crop evaluation and helps researchers identify multi-stress-resilient superior genotypes, thereby contributing to genetic improvement and ensuring sustainable production of food, fuel, and fibre in the era of limited resources and climate change.

Minimal embedded v8 engine for Ruby

Minimal embedded v8 engine for Ruby

Minimal embedded v8 engine for Ruby

Various databases of microRNA Targets.

Electrical properties of resistor networks using matrix methods.

RDF.rb plugin for parsing/serializing NTriples, RDF/XML, Turtle and RDFa data using the Raptor RDF Parser library.

Rspec-core provides the RSpec test runner and example groups.

Rspec-core provides the RSpec test runner and example groups.

This package provides a fully YAML 1.2 compliant YAML parser.

This library integrates the SASS stylesheet language into Ruby on Rails.

This library provides Ruby bindings for the Mac OSX FSEvents API.

The function RepaymentPlan() calculates repayment schedule for repayment/mortgage plans.

Robust methods for estimating the parameters of multivariate Gaussian linear models.

Provide function for work with AcademyOcean API <https://academyocean.com/api>.

This plugin provides support for handling non-OTP applications as a dependent libraries.

RSpec::Wait strives to make it easier to test asynchronous or slow interactions.

Extension to REddyProc that allows reading data from netCDF files.

This package provides functions for reading mass spectrometry data in mzXML format.