Carries out model-based clustering or classification using parsimonious Gaussian mixture models. McNicholas and Murphy (2008) <doi:10.1007/s11222-008-9056-0>, McNicholas (2010) <doi:10.1016/j.jspi.2009.11.006>, McNicholas and Murphy (2010) <doi:10.1093/bioinformatics/btq498>, McNicholas et al. (2010) <doi:10.1016/j.csda.2009.02.011>.

This package provides a collection of functions to do model-based phylogenetic analysis. It includes functions to calculate community phylogenetic diversity, to estimate correlations among functional traits while accounting for phylogenetic relationships, and to fit phylogenetic generalized linear mixed models. The Bayesian phylogenetic generalized linear mixed models are fitted with the INLA package (<https://www.r-inla.org>).

Load the Just Another Gibbs Sampling (JAGS) module pexm'. The module provides the tools to work with the Piecewise Exponential (PE) distribution in a Bayesian model with the corresponding Markov Chain Monte Carlo algorithm (Gibbs Sampling) implemented via JAGS. Details about the module implementation can be found in Mayrink et al. (2021) <doi:10.18637/jss.v100.i08>.

This package provides simple and powerful interfaces that facilitate interaction with ODBC data sources. Each data source gets its own unique and dedicated interface, wrapped around RODBC'. Communication settings are remembered between queries, and are managed silently in the background. The interfaces support multi-statement SQL scripts, which can be parameterised via metaprogramming structures and embedded R expressions.

This package provides functions to produce a fully fledged geo-spatial object extent as a SpatialPolygonsDataFrame'. Also included are functions to generate polygons from raster data using quadmesh techniques, a round number buffered extent, and general spatial-extent and raster-like extent helpers missing from the originating packages. Some latitude-based tools for polar maps are included.

This package provides a collection of functions that enable easy access and updating of a database of data over time. More specifically, the package facilitates type-2 history for data-warehouses and provides a number of Quality of life improvements for working on SQL databases with R. For reference see Ralph Kimball and Margy Ross (2013, ISBN 9781118530801).

This package provides functions for performing time domain signal coding as used in Chesmore (2001) <doi:10.1016/S0003-682X(01)00009-3>, and related tasks. This package creates the standard S-matrix and A-matrix (with variable lag), has tools to convert coding matrices into distributed matrices, provides published codebooks and allows for extraction of code sequences.

Link R with Transformers from Hugging Face to transform text variables to word embeddings; where the word embeddings are used to statistically test the mean difference between set of texts, compute semantic similarity scores between texts, predict numerical variables, and visual statistically significant words according to various dimensions etc. For more information see <https://www.r-text.org>.

Binary ties limit the richness of network analyses as relations are unique. The two-mode structure contains a number of features lost when projection it to a one-mode network. Longitudinal datasets allow for an understanding of the causal relationship among ties, which is not the case in cross-sectional datasets as ties are dependent upon each other.

This package provides a tool to define the rare biosphere. ulrb solves the problem of the definition of rarity by replacing arbitrary thresholds with an unsupervised machine learning algorithm (partitioning around medoids, or k-medoids). This algorithm works for any type of microbiome data, provided there is an abundance table. This method also works for non-microbiome data.

Semiparametric modeling of lifetime data with crossing survival curves via Yang and Prentice model with piecewise exponential baseline distribution. Details about the model can be found in Demarqui and Mayrink (2019) <arXiv:1910.02406>. Model fitting carried out via likelihood-based and Bayesian approaches. The package also provides point and interval estimation for the crossing survival times.

Fit and simulate any kind of physiologically-based kinetic ('PBK') models whatever the number of compartments. Moreover, it allows to account for any link between pairs of compartments, as well as any link of each of the compartments with the external medium. Such generic PBK models have today applications in pharmacology (PBPK models) to describe drug effects, in toxicology and ecotoxicology (PBTK models) to describe chemical substance effects. In case of exposure to a parent compound (drug or chemical) the rPBK package allows to consider metabolites, whatever their number and their phase (I, II, ...). Last but not least, package rPBK can also be used for dynamic flux balance analysis (dFBA) to deal with metabolic networks. See also Charles et al. (2022) <doi:10.1101/2022.04.29.490045>.

This package contains utilities for the analysis of Michaelian kinetic data. Beside the classical linearization methods (Lineweaver-Burk, Eadie-Hofstee, Hanes-Woolf and Eisenthal-Cornish-Bowden), features include the ability to carry out weighted regression analysis that, in most cases, substantially improves the estimation of kinetic parameters (Aledo (2021) <doi:10.1002/bmb.21522>). To avoid data transformation and the potential biases introduced by them, the package also offers functions to directly fitting data to the Michaelis-Menten equation, either using ([S], v) or (time, [S]) data. Utilities to simulate substrate progress-curves (making use of the Lambert W function) are also provided. The package is accompanied of vignettes that aim to orientate the user in the choice of the most suitable method to estimate the kinetic parameter of an Michaelian enzyme.

This package simulates continuous distributions of random vectors using Markov chain Monte Carlo (MCMC). Users specify the distribution by an R function that evaluates the log unnormalized density. Algorithms are random walk Metropolis algorithm (function metrop), simulated tempering (function temper), and morphometric random walk Metropolis (function morph.metrop), which achieves geometric ergodicity by change of variable.

mlr3 enables efficient, object-oriented programming on the building blocks of machine learning. It provides R6 objects for tasks, learners, resamplings, and measures. The package is geared towards scalability and larger datasets by supporting parallelization and out-of-memory data-backends like databases. While mlr3 focuses on the core computational operations, add-on packages provide additional functionality.

Similarly to Schafer's package pan, jomo is a package for multilevel joint modelling multiple imputation http://doi.org/10.1002/9781119942283. Novel aspects of jomo are the possibility of handling binary and categorical data through latent normal variables, the option to use cluster-specific covariance matrices and to impute compatibly with the substantive model.

The snow package provides support for simple parallel computing on a network of workstations using R. A master R process calls makeCluster to start a cluster of worker processes; the master process then uses functions such as clusterCall and clusterApply to execute R code on the worker processes and collect and return the results on the master.

Denoising Algorithm based on Relevance network Topology (DART) is an algorithm designed to evaluate the consistency of prior information molecular signatures (e.g in-vitro perturbation expression signatures) in independent molecular data (e.g gene expression data sets). If consistent, a pruning network strategy is then used to infer the activation status of the molecular signature in individual samples.

Allows you to connect to an Alfresco content management repository and interact with its contents using simple and intuitive functions. You will be able to establish a connection session to the Alfresco repository, read and upload content and manage folder hierarchies. For more details on the Alfresco content management repository see <https://www.alfresco.com/ecm-software/document-management>.

Adaptive Gauss Hermite Quadrature for Bayesian inference. The AGHQ method for normalizing posterior distributions and making Bayesian inferences based on them. Functions are provided for doing quadrature and marginal Laplace approximations, and summary methods are provided for making inferences based on the results. See Stringer (2021). "Implementing Adaptive Quadrature for Bayesian Inference: the aghq Package" <arXiv:2101.04468>.

This package performs logistic regression for binary longitudinal data, allowing for serial dependence among observations from a given individual and a random intercept term. Estimation is via maximization of the exact likelihood of a suitably defined model. Missing values and unbalanced data are allowed, with some restrictions. M. Helena Goncalves et al.(2007) <DOI: 10.18637/jss.v046.i09>.

CEU (CEU San Pablo University) Mass Mediator is an on-line tool for aiding researchers in performing metabolite annotation. cmmr (CEU Mass Mediator RESTful API) allows for programmatic access in R: batch search, batch advanced search, MS/MS (tandem mass spectrometry) search, etc. For more information about the API Endpoint please go to <https://github.com/YaoxiangLi/cmmr>.

Connect and pull data from the CJA API, which powers CJA Workspace <https://github.com/AdobeDocs/cja-apis>. The package was developed with the analyst in mind and will continue to be developed with the guiding principles of iterative, repeatable, timely analysis. New features are actively being developed and we value your feedback and contribution to the process.

Improves the balance of optimal matching with near-fine balance by giving penalties on the unbalanced covariates with the unbalanced directions. Many directional penalties can also be viewed as Lagrange multipliers, pushing a matched sample in the direction of satisfying a linear constraint that would not be satisfied without penalization. Yu and Rosenbaum (2019) <doi:10.1111/biom.13098>.