This comprehensive toolkit for skewed regression is designated as "SLIC" (The LIC for Distributed Skewed Regression Analysis). It is predicated on the assumption that the error term follows a skewed distribution, such as the Skew-Normal, Skew-t, or Skew-Laplace. The methodology and theoretical foundation of the package are described in Guo G.(2020) <doi:10.1080/02664763.2022.2053949>.

This package provides a workflow based on scTenifoldNet to perform in-silico knockout experiments using single-cell RNA sequencing (scRNA-seq) data from wild-type (WT) control samples as input. First, the package constructs a single-cell gene regulatory network (scGRN) and knocks out a target gene from the adjacency matrix of the WT scGRN by setting the geneâ s outdegree edges to zero. Then, it compares the knocked out scGRN with the WT scGRN to identify differentially regulated genes, called virtual-knockout perturbed genes, which are used to assess the impact of the gene knockout and reveal the geneâ s function in the analyzed cells.

This package provides a convenient interface to the staticrypt by Robin Moisson <https://github.com/robinmoisson/staticrypt>---'Node.js package for adding a password protection layer to static HTML pages. This package can be integrated into the post-render process of quarto documents to secure them with a password.

An R API providing access to a relational database with macroeconomic time series data for South Africa, obtained from the South African Reserve Bank (SARB) and Statistics South Africa (STATSSA), and updated on a weekly basis via the EconData <https://www.econdata.co.za/> platform and automated scraping of the SARB and STATSSA websites. The database is maintained at the Department of Economics at Stellenbosch University.

Density, distribution function, quantile function and random generation for the skewed t distribution of Fernandez and Steel.

This package provides functions for fitting Cliff-Ord-type spatial autoregressive models with and without heteroskedastic innovations using Generalized Method of Moments estimation are provided. Some support is available for fitting spatial HAC models, and for fitting with non-spatial endogeneous variables using instrumental variables.

This package provides an imputation pipeline for single-cell RNA sequencing data. The scISR method uses a hypothesis-testing technique to identify zero-valued entries that are most likely affected by dropout events and estimates the dropout values using a subspace regression model (Tran et.al. (2022) <DOI:10.1038/s41598-022-06500-4>).

Allows to retrieve time series of all indicators available in the Bank of Mexico's Economic Information System (<http://www.banxico.org.mx/SieInternet/>).

An implementation of Simultaneous Truth and Performance Level Estimation (STAPLE) <doi:10.1109/TMI.2004.828354>. This method is used when there are multiple raters for an object, typically an image, and this method fuses these ratings into one rating. It uses an expectation-maximization method to estimate this rating and the individual specificity/sensitivity for each rater.

Population genetics package for designing diagnostic panels. Candidate markers, marker combinations, and different panel sizes are assessed for how well they can predict the source population of known samples. Requires a genotype file of candidate markers in STRUCTURE format. Methods for population cross-validation are described in Jombart (2008) <doi:10.1093/bioinformatics/btn129>.

Implementation of a model-based bootstrap approach for testing whether two formulations are similar. The package provides a function for fitting a pharmacokinetic model to time-concentration data and comparing the results for all five candidate models regarding the Residual Sum of Squares (RSS). The candidate set contains a First order, Hixson-Crowell, Higuchi, Weibull and a logistic model. The assessment of similarity implemented in this package is performed regarding the maximum deviation of the profiles. See Moellenhoff et al. (2018) <doi:10.1002/sim.7689> for details.

An efficient tool for fitting nested mixture models based on a shared set of atoms via Markov Chain Monte Carlo and variational inference algorithms. Specifically, the package implements the common atoms model (Denti et al., 2023), its finite version (similar to D'Angelo et al., 2023), and a hybrid finite-infinite model (D'Angelo and Denti, 2024). All models implement univariate nested mixtures with Gaussian kernels equipped with a normal-inverse gamma prior distribution on the parameters. Additional functions are provided to help analyze the results of the fitting procedure. References: Denti, Camerlenghi, Guindani, Mira (2023) <doi:10.1080/01621459.2021.1933499>, Dâ Angelo, Canale, Yu, Guindani (2023) <doi:10.1111/biom.13626>, Dâ Angelo, Denti (2024) <doi:10.1214/24-BA1458>.

Get started with new projects by dropping a skeleton of a new project into a new or existing directory, initialise git repositories, and create reproducible environments with the renv package. The package allows for dynamically named files, folders, file content, as well as the functionality to drop individual template files into existing projects.

This package creates a data specification that describes the columns of a table (data.frame). Provides methods to read, write, and update the specification. Checks whether a table matches its specification. See specification.data.frame(),read.spec(), write.spec(), as.csv.spec(), respecify.character(), and %matches%.data.frame().

Sonification (or audification) is the process of representing data by sounds in the audible range. This package provides the R function sonify() that transforms univariate data, sampled at regular or irregular intervals, into a continuous sound with time-varying frequency. The ups and downs in frequency represent the ups and downs in the data. Sonify provides a substitute for R's plot function to simplify data analysis for the visually impaired.

Fork of vote_2.3-2', Raftery et al. (2021) <DOI:10.32614/RJ-2021-086>, with additional support for stochastic experimentation.

Fast multi-trait and multi-trail Genome Wide Association Studies (GWAS) following the method described in Zhou and Stephens. (2014), <doi:10.1038/nmeth.2848>. One of a series of statistical genetic packages for streamlining the analysis of typical plant breeding experiments developed by Biometris.

This package provides utilities for generating SQL queries (particularly CREATE TABLE statements) from R model objects. The most important use case is generating SQL to score a generalized linear model or related model represented as an R object, in which case the package handles parsing formula operators and including the model's response function.

Efficiently estimate shape parameters of periodic time series imagery with which a statistical seasonal trend analysis (STA) is subsequently performed. STA output can be exported in conventional raster formats. Methods to visualize STA output are also implemented as well as the calculation of additional basic statistics. STA is based on (R. Eastman, F. Sangermano, B. Ghimire, H. Zhu, H. Chen, N. Neeti, Y. Cai, E. Machado and S. Crema, 2009) <doi:10.1080/01431160902755338>.

Chat with large language models on your machine without internet with complete privacy via ollama', powered by R shiny interface. For more information on ollama', visit <https://ollama.com>.

Exploratory analysis on any input data describing the structure and the relationships present in the data. The package automatically select the variable and does related descriptive statistics. Analyzing information value, weight of evidence, custom tables, summary statistics, graphical techniques will be performed for both numeric and categorical predictors.

This package provides functions for dimension reduction through the seeded canonical correlation analysis are provided. A classical canonical correlation analysis (CCA) is one of useful statistical methods in multivariate data analysis, but it is limited in use due to the matrix inversion for large p small n data. To overcome this, a seeded CCA has been proposed in Im, Gang and Yoo (2015) \doi10.1002/cem.2691. The seeded CCA is a two-step procedure. The sets of variables are initially reduced by successively projecting cov(X,Y) or cov(Y,X) onto cov(X) and cov(Y), respectively, without loss of information on canonical correlation analysis, following Cook, Li and Chiaromonte (2007) \doi10.1093/biomet/asm038 and Lee and Yoo (2014) \doi10.1111/anzs.12057. Then, the canonical correlation is finalized with the initially-reduced two sets of variables.

Simulates the cultural evolution of quantitative traits of bird song. SongEvo is an individual- (agent-) based model. SongEvo is spatially-explicit and can be parameterized with, and tested against, measured song data. Functions are available for model implementation, sensitivity analyses, parameter optimization, model validation, and hypothesis testing.

High dimensional time to events data analysis with variable selection technique. Currently support LASSO, clustering and Bonferroni's correction.